PKCα mediates acetylcholine-induced activation of TRPV4-dependent calcium influx in endothelial cells

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 301, Issue 3, 2011, Pages

  Adapala, Ravi K ^a   Talasila, Phani K ^a   Bratz, Ian N ^a   Zhang, David X ^b   Suzuki, Makoto ^c   Gary Meszaros, J ^a   Thodeti, Charles K ^a  

^a Northeast Ohio Medical University   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

^c JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Acetylcholine; Calcium influx; Endothelial cell; Protein kinase C; Transient receptor potential vanilloid channel 4

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; AB 159908; ACETYLCHOLINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C ALPHA; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 4; VANILLOID RECEPTOR ANTAGONIST;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM SIGNALING; CALCIUM TRANSPORT; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; MALE; MESENTERIC ARTERY; MICROVASCULAR ENDOTHELIAL CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; VASODILATATION;

ACETYLCHOLINE; ANIMALS; CALCIUM SIGNALING; CARBAZOLES; CELLS, CULTURED; ENDOTHELIAL CELLS; ENZYME ACTIVATION; MALE; MESENTERIC ARTERIES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTATION; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHORYLATION; PROTEIN KINASE C-ALPHA; PROTEIN KINASE INHIBITORS; TETRADECANOYLPHORBOL ACETATE; TIME FACTORS; TRANSFECTION; TRPV CATION CHANNELS; VASODILATION; VASODILATOR AGENTS;

EID: 80052324633     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00142.2011     Document Type: Article

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