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Volumn 64, Issue , 2014, Pages 387-395

Chemopreventive effects of standardized papaya leaf fraction on oxidatively stressed human liver cells

Author keywords

Antioxidant; Carica papaya L; hmox 1; nqo 1; nrf 2; Oxidative stress

Indexed keywords

OXIDATIVE STRESS;

EID: 84907726387     PISSN: 09639969     EISSN: None     Source Type: Journal    
DOI: 10.1016s/j.foodres.2014.06.040     Document Type: Article
Times cited : (1)

References (39)
  • 1
    • 17644390182 scopus 로고    scopus 로고
    • Response of the antioxidant defense system to tert-butyl hydroperoxide and hydrogen peroxide in a human hepatoma cell line (HepG2)
    • Alía M., Ramos S., Mateos R., Bravo L., Goya L. Response of the antioxidant defense system to tert-butyl hydroperoxide and hydrogen peroxide in a human hepatoma cell line (HepG2). Journal of Biochemical and Molecular Toxicology 2005, 19:119-128.
    • (2005) Journal of Biochemical and Molecular Toxicology , vol.19 , pp. 119-128
    • Alía, M.1    Ramos, S.2    Mateos, R.3    Bravo, L.4    Goya, L.5
  • 3
    • 0032469832 scopus 로고    scopus 로고
    • Oxidative stress and superoxide dismutase in development, aging and gene regulation
    • Allen R.G. Oxidative stress and superoxide dismutase in development, aging and gene regulation. Age 1998, 21:47-76.
    • (1998) Age , vol.21 , pp. 47-76
    • Allen, R.G.1
  • 4
    • 84904757228 scopus 로고    scopus 로고
    • Future treatments: Antifibrotic agents, nitric oxide donors, and gene therapy in the treatment of portal hypertension
    • Humana Press Inc, New Jersey, A.J. Sanyal, V.H. Shah (Eds.) Clinical gastroenterology
    • Bansal M.B., Friedman S.L. Future treatments: Antifibrotic agents, nitric oxide donors, and gene therapy in the treatment of portal hypertension. Portal hypertension 2005, 485-503. Humana Press Inc, New Jersey. A.J. Sanyal, V.H. Shah (Eds.).
    • (2005) Portal hypertension , pp. 485-503
    • Bansal, M.B.1    Friedman, S.L.2
  • 5
    • 0033795435 scopus 로고    scopus 로고
    • Inhibition of tert-butyl hydroperoxide-induced cell membrane bleb formation by alpha-tocopherol and glutathione
    • Chen H.W., Chiang T., Wang C.Y., Lii C.K. Inhibition of tert-butyl hydroperoxide-induced cell membrane bleb formation by alpha-tocopherol and glutathione. Food and Chemical Toxicology 2000, 38:1089-1096.
    • (2000) Food and Chemical Toxicology , vol.38 , pp. 1089-1096
    • Chen, H.W.1    Chiang, T.2    Wang, C.Y.3    Lii, C.K.4
  • 6
    • 18844402874 scopus 로고    scopus 로고
    • Resveratrol upregulates heme oxygenase-1 expression via activation of NF-E2-related factor 2 in PC12 cells
    • Chen C.Y., Jang J.H., Li M.H., Surh Y.J. Resveratrol upregulates heme oxygenase-1 expression via activation of NF-E2-related factor 2 in PC12 cells. Biochemical and Biophysical Research Communications 2005, 331:993-1000.
    • (2005) Biochemical and Biophysical Research Communications , vol.331 , pp. 993-1000
    • Chen, C.Y.1    Jang, J.H.2    Li, M.H.3    Surh, Y.J.4
  • 7
    • 84861994776 scopus 로고    scopus 로고
    • Effect of flaxseed oil fortified with vitamin E and phytosterols on antioxidant defense capacities and lipids profile in rats
    • Deng Q., Yu X., Xu J., Liu C., Huang F., Huang Q., et al. Effect of flaxseed oil fortified with vitamin E and phytosterols on antioxidant defense capacities and lipids profile in rats. Journal of Food Science 2012, 77:135-140.
    • (2012) Journal of Food Science , vol.77 , pp. 135-140
    • Deng, Q.1    Yu, X.2    Xu, J.3    Liu, C.4    Huang, F.5    Huang, Q.6
  • 8
    • 70350571097 scopus 로고    scopus 로고
    • Cytoprotective effects of pu-erh tea on hepatotoxicity in vitro and in vivo induced by tert-butyl-hydroperoxide
    • Duh P.-D., Wang B.S., Liou S.-J., Lin C.-J. Cytoprotective effects of pu-erh tea on hepatotoxicity in vitro and in vivo induced by tert-butyl-hydroperoxide. Food Chemistry 2010, 119:580-585.
    • (2010) Food Chemistry , vol.119 , pp. 580-585
    • Duh, P.-D.1    Wang, B.S.2    Liou, S.-J.3    Lin, C.-J.4
  • 9
    • 78249255217 scopus 로고    scopus 로고
    • α-Tocopherol is an effective phase II enzyme inducer: Protective effects on acrolein-induced oxidative stress and mitochondrial dysfunction in human retinal pigment epithelial cells
    • Feng Z., Liu Z., Li X., Jia H., Sun L., Tian C., et al. α-Tocopherol is an effective phase II enzyme inducer: Protective effects on acrolein-induced oxidative stress and mitochondrial dysfunction in human retinal pigment epithelial cells. Journal of Nutritional Biochemistry 2010, 21:1222-1231.
    • (2010) Journal of Nutritional Biochemistry , vol.21 , pp. 1222-1231
    • Feng, Z.1    Liu, Z.2    Li, X.3    Jia, H.4    Sun, L.5    Tian, C.6
  • 10
    • 20444396613 scopus 로고    scopus 로고
    • Quinone oxidoreductases in protection against myelogenous hyperplasia and benzene toxicity
    • Iskander K., Jaiswal A.K. Quinone oxidoreductases in protection against myelogenous hyperplasia and benzene toxicity. Chemico-Biological Interactions 2005, 153-154:147-157.
    • (2005) Chemico-Biological Interactions , pp. 147-157
    • Iskander, K.1    Jaiswal, A.K.2
  • 11
    • 0037676086 scopus 로고    scopus 로고
    • Screening and comparison of antioxidant activity of solvent extracts of herbal medicines used in Korea
    • Kang D.G., Yun C.K., Lee H.S. Screening and comparison of antioxidant activity of solvent extracts of herbal medicines used in Korea. Journal of Ethnopharmacology 2003, 87:231-236.
    • (2003) Journal of Ethnopharmacology , vol.87 , pp. 231-236
    • Kang, D.G.1    Yun, C.K.2    Lee, H.S.3
  • 13
    • 33749019130 scopus 로고    scopus 로고
    • Mechanism of action of sulforaphane: Inhibition of p38 mitogen-activated protein kinase isoforms contributing to the induction of antioxidant response element-mediated heme oxygenase-1 in human hepatoma HepG2 cells
    • Keum Y.S., Yu S., Chang P.P., Yuan X., Kim J.H., Xu C., et al. Mechanism of action of sulforaphane: Inhibition of p38 mitogen-activated protein kinase isoforms contributing to the induction of antioxidant response element-mediated heme oxygenase-1 in human hepatoma HepG2 cells. Cancer Research 2006, 66:8804-8813.
    • (2006) Cancer Research , vol.66 , pp. 8804-8813
    • Keum, Y.S.1    Yu, S.2    Chang, P.P.3    Yuan, X.4    Kim, J.H.5    Xu, C.6
  • 14
    • 0024263599 scopus 로고
    • Tert-butyl hydroperoxide-induced hemolysis of alpha-tocopherol-decreased erythrocytes from selenium-deficient and selenium-adequate rats
    • Kim C.H., Yasumoto K., Suzuki T., Yoshida M. Tert-butyl hydroperoxide-induced hemolysis of alpha-tocopherol-decreased erythrocytes from selenium-deficient and selenium-adequate rats. Journal of Nutritional Science and Vitaminology 1988, 34:481-490.
    • (1988) Journal of Nutritional Science and Vitaminology , vol.34 , pp. 481-490
    • Kim, C.H.1    Yasumoto, K.2    Suzuki, T.3    Yoshida, M.4
  • 15
    • 0036240610 scopus 로고    scopus 로고
    • Enhanced expression of the transcription factor Nrf-2 by cancer chemopreventive agents: Role of antioxidant response element-like sequences in the Nrf-2 promoter
    • Kwak M.K., Itoh K., Yamamoto M., Kensler T.W. Enhanced expression of the transcription factor Nrf-2 by cancer chemopreventive agents: Role of antioxidant response element-like sequences in the Nrf-2 promoter. Molecular and Cellular Biology 2002, 22:2883-2892.
    • (2002) Molecular and Cellular Biology , vol.22 , pp. 2883-2892
    • Kwak, M.K.1    Itoh, K.2    Yamamoto, M.3    Kensler, T.W.4
  • 16
    • 77957331598 scopus 로고    scopus 로고
    • A polyacetylene from Gymnaster koraiensis exerts hepatoprotective effects in vivo and in vitro
    • Lee S.B., Kang K., Oidovsambuu S., Jho E.H., Yun J.H., Yoo J.-H., et al. A polyacetylene from Gymnaster koraiensis exerts hepatoprotective effects in vivo and in vitro. Food and Chemical Toxicology 2010, 48:3035-3041.
    • (2010) Food and Chemical Toxicology , vol.48 , pp. 3035-3041
    • Lee, S.B.1    Kang, K.2    Oidovsambuu, S.3    Jho, E.H.4    Yun, J.H.5    Yoo, J.-H.6
  • 17
    • 33749519154 scopus 로고    scopus 로고
    • Phenolic compounds protect HepG2 cells from oxidative damage: Relevance of glutathione levels
    • Lima C.F., Fernandes-Ferreira M., Pereira-Wilson C. Phenolic compounds protect HepG2 cells from oxidative damage: Relevance of glutathione levels. Life Sciences 2006, 79:2056-2068.
    • (2006) Life Sciences , vol.79 , pp. 2056-2068
    • Lima, C.F.1    Fernandes-Ferreira, M.2    Pereira-Wilson, C.3
  • 18
    • 9744222928 scopus 로고    scopus 로고
    • Potential synergy of phytochemicals in cancer prevention: Mechanisms of action
    • Liu R.H. Potential synergy of phytochemicals in cancer prevention: Mechanisms of action. Journal of Nutrition 2004, 134:3479S-3485S.
    • (2004) Journal of Nutrition , vol.134 , pp. 3479S-3485S
    • Liu, R.H.1
  • 21
    • 0033595104 scopus 로고    scopus 로고
    • The antioxidant defense protein ferritin is a novel and specific target for Pentaerithrityl tetranitrate in endothelial cells
    • Oberle S., Schwartz P., Abate A., Schroder H. The antioxidant defense protein ferritin is a novel and specific target for Pentaerithrityl tetranitrate in endothelial cells. Biochemical and Biophysical Research Communications 1999, 261:28-34.
    • (1999) Biochemical and Biophysical Research Communications , vol.261 , pp. 28-34
    • Oberle, S.1    Schwartz, P.2    Abate, A.3    Schroder, H.4
  • 22
    • 68949194687 scopus 로고    scopus 로고
    • Characterization of the antioxidant properties of hydrophilic and lipophilic extracts of Jute (Corchorus olitorius) leaf
    • Oboh G., Raddatz H., Henle T. Characterization of the antioxidant properties of hydrophilic and lipophilic extracts of Jute (Corchorus olitorius) leaf. International Journal of Food Sciences and Nutrition 2009, 60:124-134.
    • (2009) International Journal of Food Sciences and Nutrition , vol.60 , pp. 124-134
    • Oboh, G.1    Raddatz, H.2    Henle, T.3
  • 23
    • 76149088076 scopus 로고    scopus 로고
    • Aqueous extract of Carica papaya leaves exhibits anti-tumor activity and immunomodulatory effects
    • Otsuki N., Dang N.H., Kumagai E., Kondo A., Iwata S., Morimoto C. Aqueous extract of Carica papaya leaves exhibits anti-tumor activity and immunomodulatory effects. Journal of Ethnopharmacology 2010, 127:760-767.
    • (2010) Journal of Ethnopharmacology , vol.127 , pp. 760-767
    • Otsuki, N.1    Dang, N.H.2    Kumagai, E.3    Kondo, A.4    Iwata, S.5    Morimoto, C.6
  • 26
    • 68849110158 scopus 로고    scopus 로고
    • Synergic effects of α-tocopherol and β-carotene on tert-butyl hydroperoxide-induced HepG2 cell injury
    • Park S., Kim A.J., Lee M. Synergic effects of α-tocopherol and β-carotene on tert-butyl hydroperoxide-induced HepG2 cell injury. Toxicology and Industrial Health 2009, 25:311-320.
    • (2009) Toxicology and Industrial Health , vol.25 , pp. 311-320
    • Park, S.1    Kim, A.J.2    Lee, M.3
  • 27
    • 77955472869 scopus 로고    scopus 로고
    • Lipophilic phenolic antioxidants: Correlation between antioxidant profile, partition coefficients and redox properties
    • Roleira F.M., Siquet C., Orrù E., Garrido E.M., Garrido J., Milhazes N., et al. Lipophilic phenolic antioxidants: Correlation between antioxidant profile, partition coefficients and redox properties. Bioorganic and Medicinal Chemistry 2010, 18:5816-5825.
    • (2010) Bioorganic and Medicinal Chemistry , vol.18 , pp. 5816-5825
    • Roleira, F.M.1    Siquet, C.2    Orrù, E.3    Garrido, E.M.4    Garrido, J.5    Milhazes, N.6
  • 29
    • 0029872210 scopus 로고    scopus 로고
    • Apoptosis induced by transforming growth factor-β in fetal hepatocyte primary cultures
    • Sanchez A., Alvarez A.M., Benito M., Fabregat I. Apoptosis induced by transforming growth factor-β in fetal hepatocyte primary cultures. Journal of Biological Chemistry 1996, 271:7416-7422.
    • (1996) Journal of Biological Chemistry , vol.271 , pp. 7416-7422
    • Sanchez, A.1    Alvarez, A.M.2    Benito, M.3    Fabregat, I.4
  • 30
    • 0037093340 scopus 로고    scopus 로고
    • Plant-derived phenolic compounds prevent the DNA single-strand breakage and cytotoxicity induced by tert-butyl hydroperoxide via an iron-chelating mechanism
    • Sestili P., Diamantini G., Bedini A., Cerioni L., Tommasini I., Tarzia G., et al. Plant-derived phenolic compounds prevent the DNA single-strand breakage and cytotoxicity induced by tert-butyl hydroperoxide via an iron-chelating mechanism. Biochemical Journal 2002, 364:121-128.
    • (2002) Biochemical Journal , vol.364 , pp. 121-128
    • Sestili, P.1    Diamantini, G.2    Bedini, A.3    Cerioni, L.4    Tommasini, I.5    Tarzia, G.6
  • 31
    • 56249106571 scopus 로고    scopus 로고
    • Nrf-2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals
    • Surh Y.J., Kundu J.K., Na H.K. Nrf-2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals. Planta Medica 2008, 74:1526-1539.
    • (2008) Planta Medica , vol.74 , pp. 1526-1539
    • Surh, Y.J.1    Kundu, J.K.2    Na, H.K.3
  • 32
    • 84904739629 scopus 로고    scopus 로고
    • Protective effects of papaya extracts on tert-butyl hydroperoxide mediated oxidative injury to human liver cells (An in-vitro study)
    • Tan S.-A., Ramos S., Martin M.A., Mateos R., Harvey M., Ramanathan S., et al. Protective effects of papaya extracts on tert-butyl hydroperoxide mediated oxidative injury to human liver cells (An in-vitro study). Free Radicals and Antioxidants 2012, 2:10-19.
    • (2012) Free Radicals and Antioxidants , vol.2 , pp. 10-19
    • Tan, S.-A.1    Ramos, S.2    Martin, M.A.3    Mateos, R.4    Harvey, M.5    Ramanathan, S.6
  • 35
    • 0000191753 scopus 로고
    • Lactate dehydrogenase: UV method with pyruvate and NADH
    • Verlag Chemie, Dearfield Beach, H.U. Bergmayer (Ed.)
    • Vassault A. Lactate dehydrogenase: UV method with pyruvate and NADH. Methods of enzymatic analysis 1983, 118-126. Verlag Chemie, Dearfield Beach. H.U. Bergmayer (Ed.).
    • (1983) Methods of enzymatic analysis , pp. 118-126
    • Vassault, A.1
  • 36
    • 0032820452 scopus 로고
    • Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader
    • Wang H., Joseph J.A. Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader. Free Radical Biology and Medicine 1993, 27:612-616.
    • (1993) Free Radical Biology and Medicine , vol.27 , pp. 612-616
    • Wang, H.1    Joseph, J.A.2
  • 37
    • 79951975847 scopus 로고    scopus 로고
    • Anti-inflammatory/anti-oxidative stress activities and differential regulation of Nrf2-mediated genes by non-polar fractions of tea Chrysanthemum zawadskii and licorice Glycyrrhiza uralensis
    • Wu T.Y., Khor T.O., Saw C.L., Loh S.C., Chen A.I., Lim S.S., et al. Anti-inflammatory/anti-oxidative stress activities and differential regulation of Nrf2-mediated genes by non-polar fractions of tea Chrysanthemum zawadskii and licorice Glycyrrhiza uralensis. American Association of Pharmaceutical Scientists Journals 2011, 13:1-13.
    • (2011) American Association of Pharmaceutical Scientists Journals , vol.13 , pp. 1-13
    • Wu, T.Y.1    Khor, T.O.2    Saw, C.L.3    Loh, S.C.4    Chen, A.I.5    Lim, S.S.6
  • 38
    • 34347392509 scopus 로고    scopus 로고
    • Quercetin protects human hepatocytes from ethanol-derived oxidative stress by inducing heme oxygenase-1 via the MAPK/Nrf-2 pathways
    • Yao P., Nussler A., Liu L., Hao L., Song F., Schirmeier A., et al. Quercetin protects human hepatocytes from ethanol-derived oxidative stress by inducing heme oxygenase-1 via the MAPK/Nrf-2 pathways. Journal of Hepatology 2007, 47:253-261.
    • (2007) Journal of Hepatology , vol.47 , pp. 253-261
    • Yao, P.1    Nussler, A.2    Liu, L.3    Hao, L.4    Song, F.5    Schirmeier, A.6
  • 39
    • 33646251405 scopus 로고    scopus 로고
    • The antioxidant effect of free bilirubin on cumene-hydroperoxide treated human leukocytes
    • Yesilkaya A., Altinayak R., Korgun D.K. The antioxidant effect of free bilirubin on cumene-hydroperoxide treated human leukocytes. General Pharmacology 2000, 35:17-20.
    • (2000) General Pharmacology , vol.35 , pp. 17-20
    • Yesilkaya, A.1    Altinayak, R.2    Korgun, D.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.