-
2
-
-
84990082204
-
Cataract, deafness, cerebellar ataxia, psychosis and dementia- a new syndrome
-
Strömgren E, Dalby A, Dalby MA, Ranheim B, (1970) Cataract, deafness, cerebellar ataxia, psychosis and dementia- a new syndrome. Acta Neurol Scand 46 (S43) (): 261.
-
(1970)
Acta Neurol Scand
, vol.46
, Issue.S43
, pp. 261
-
-
Strömgren, E.1
Dalby, A.2
Dalby, M.A.3
Ranheim, B.4
-
3
-
-
0033600228
-
A stop-codon mutation in the BRI gene associated with familial British dementia
-
Vidal R, Frangione B, Rostagno A, Mead S, Revesz T, et al. (1999) A stop-codon mutation in the BRI gene associated with familial British dementia. Nature 399: 776-781.
-
(1999)
Nature
, vol.399
, pp. 776-781
-
-
Vidal, R.1
Frangione, B.2
Rostagno, A.3
Mead, S.4
Revesz, T.5
-
4
-
-
0034712749
-
A decamer duplication in the 3′ region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred
-
Vidal R, Revesz T, Rostagno A, Kim E, Holton JL, et al. (2000) A decamer duplication in the 3′ region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred. Proc Natl Acad Sci USA 97: 4920-4925.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 4920-4925
-
-
Vidal, R.1
Revesz, T.2
Rostagno, A.3
Kim, E.4
Holton, J.L.5
-
5
-
-
3843069669
-
Neurodegeneration caused by proteins with an aberrant carboxyl-terminus
-
Vidal R, Delisle MB, Ghetti B, (2004) Neurodegeneration caused by proteins with an aberrant carboxyl-terminus. J Neuropathol Exp Neurol 63: 787-800.
-
(2004)
J Neuropathol Exp Neurol
, vol.63
, pp. 787-800
-
-
Vidal, R.1
Delisle, M.B.2
Ghetti, B.3
-
6
-
-
0035925577
-
Sequence, genomic structure and tissue expression of Human BRI3, a member of the BRI gene family
-
Vidal R, Calero M, Revesz T, Plant G, Ghiso J, et al. (2001) Sequence, genomic structure and tissue expression of Human BRI3, a member of the BRI gene family. Gene 266: 95-102.
-
(2001)
Gene
, vol.266
, pp. 95-102
-
-
Vidal, R.1
Calero, M.2
Revesz, T.3
Plant, G.4
Ghiso, J.5
-
7
-
-
0033352083
-
Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia
-
Kim SH, Wang R, Gordon DJ, Bass J, Steiner DF, et al. (1999) Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia. Nat Neurosci 2: 984-988.
-
(1999)
Nat Neurosci
, vol.2
, pp. 984-988
-
-
Kim, S.H.1
Wang, R.2
Gordon, D.J.3
Bass, J.4
Steiner, D.F.5
-
8
-
-
0037127261
-
Proteolytic processing of familial British dementia-associated BRI variants: evidence for enhanced intracellular accumulation of amyloidogenic peptides
-
Kim SH, Creemers JW, Chu S, Thinakaran G, Sisodia SS, (2002) Proteolytic processing of familial British dementia-associated BRI variants: evidence for enhanced intracellular accumulation of amyloidogenic peptides. J Biol Chem 277: 1872-1877.
-
(2002)
J Biol Chem
, vol.277
, pp. 1872-1877
-
-
Kim, S.H.1
Creemers, J.W.2
Chu, S.3
Thinakaran, G.4
Sisodia, S.S.5
-
9
-
-
1442265701
-
Axonal transport of British and Danish amyloid peptides via secretory vesicles
-
Choi SI, Vidal R, Frangione B, Levy E, (2004) Axonal transport of British and Danish amyloid peptides via secretory vesicles. FASEB J 18: 373-375.
-
(2004)
FASEB J
, vol.18
, pp. 373-375
-
-
Choi, S.I.1
Vidal, R.2
Frangione, B.3
Levy, E.4
-
10
-
-
0036629254
-
BRICHOS: a conserved domain in proteins associated with dementia, respiratory distress and cancer
-
Sanchez-Pulido L, Devos D, Valencia A, (2002) BRICHOS: a conserved domain in proteins associated with dementia, respiratory distress and cancer. Trends Biochem Sci 27: 329-332.
-
(2002)
Trends Biochem Sci
, vol.27
, pp. 329-332
-
-
Sanchez-Pulido, L.1
Devos, D.2
Valencia, A.3
-
11
-
-
38349144907
-
Regulated intramembrane proteolysis of Bri2 (Itm2b) by ADAM10 and SPPL2a/SPPL2b
-
Martin L, Fluhrer R, Reiss K, Kremmer E, Saftig P, et al. (2008) Regulated intramembrane proteolysis of Bri2 (Itm2b) by ADAM10 and SPPL2a/SPPL2b. J Biol Chem 283: 1644-1652.
-
(2008)
J Biol Chem
, vol.283
, pp. 1644-1652
-
-
Martin, L.1
Fluhrer, R.2
Reiss, K.3
Kremmer, E.4
Saftig, P.5
-
12
-
-
65549161929
-
Substrate requirements for SPPL2b-dependent regulated intramembrane proteolysis
-
Martin L, Fluhrer R, Haass C, (2009) Substrate requirements for SPPL2b-dependent regulated intramembrane proteolysis. J Biol Chem 284: 5662-5670.
-
(2009)
J Biol Chem
, vol.284
, pp. 5662-5670
-
-
Martin, L.1
Fluhrer, R.2
Haass, C.3
-
13
-
-
0035137042
-
Regional distribution of amyloid-Bri deposition and its association with neurofibrillary degeneration in familial British dementia
-
Holton JL, Ghiso J, Lashley T, Rostagno A, Guerin CJ, et al. (2001) Regional distribution of amyloid-Bri deposition and its association with neurofibrillary degeneration in familial British dementia. Am J Pathol 158: 515-526.
-
(2001)
Am J Pathol
, vol.158
, pp. 515-526
-
-
Holton, J.L.1
Ghiso, J.2
Lashley, T.3
Rostagno, A.4
Guerin, C.J.5
-
14
-
-
0036194067
-
Familial Danish dementia: a novel form of cerebral amyloidosis associated with deposition of both amyloid-Dan and amyloid-beta
-
Holton JL, Lashley T, Ghiso J, Braendgaard H, Vidal R, et al. (2002) Familial Danish dementia: a novel form of cerebral amyloidosis associated with deposition of both amyloid-Dan and amyloid-beta. J Neuropathol Exp Neurol 61: 254-267.
-
(2002)
J Neuropathol Exp Neurol
, vol.61
, pp. 254-267
-
-
Holton, J.L.1
Lashley, T.2
Ghiso, J.3
Braendgaard, H.4
Vidal, R.5
-
15
-
-
0024856333
-
Gerstmann-Sträussler-Scheinker disease. II. Neurofibrillary tangles and plaques with PrP-amyloid coexist in an affected family
-
Ghetti B, Tagliavini F, Masters CL, Beyreuther K, Giaccone G, et al. (1989) Gerstmann-Sträussler-Scheinker disease. II. Neurofibrillary tangles and plaques with PrP-amyloid coexist in an affected family. Neurology 39: 1453-1461.
-
(1989)
Neurology
, vol.39
, pp. 1453-1461
-
-
Ghetti, B.1
Tagliavini, F.2
Masters, C.L.3
Beyreuther, K.4
Giaccone, G.5
-
16
-
-
0025013882
-
Neurofibrillary tangles of the Indiana kindred of Gerstmann-Sträussler-Scheinker disease share antigenic determinants with those of Alzheimer disease
-
Giaccone G, Tagliavini F, Verga L, Frangione B, Farlow MR, et al. (1990) Neurofibrillary tangles of the Indiana kindred of Gerstmann-Sträussler-Scheinker disease share antigenic determinants with those of Alzheimer disease. Brain Res 530: 325-329.
-
(1990)
Brain Res
, vol.530
, pp. 325-329
-
-
Giaccone, G.1
Tagliavini, F.2
Verga, L.3
Frangione, B.4
Farlow, M.R.5
-
17
-
-
53849100694
-
Tauopathy in human and experimental variant Creutzfeldt-Jakob disease
-
Giaccone G, Mangieri M, Capobianco R, Limido L, Hauw JJ, et al. (2008) Tauopathy in human and experimental variant Creutzfeldt-Jakob disease. Neurobiol Aging 29: 1864-1873.
-
(2008)
Neurobiol Aging
, vol.29
, pp. 1864-1873
-
-
Giaccone, G.1
Mangieri, M.2
Capobianco, R.3
Limido, L.4
Hauw, J.J.5
-
18
-
-
77950461334
-
Modeling familial British and Danish dementia
-
Garringer HJ, Murrell J, D'Adamio L, Ghetti B, Vidal R, (2010) Modeling familial British and Danish dementia. Brain Struct Funct 214: 235-244.
-
(2010)
Brain Struct Funct
, vol.214
, pp. 235-244
-
-
Garringer, H.J.1
Murrell, J.2
D'Adamio, L.3
Ghetti, B.4
Vidal, R.5
-
19
-
-
0041689948
-
Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease
-
Gamblin TC, Chen F, Zambrano A, Abraha A, Lagalwar S, et al. (2003) Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease. Proc Natl Acad Sci USA 100: 10032-10037.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 10032-10037
-
-
Gamblin, T.C.1
Chen, F.2
Zambrano, A.3
Abraha, A.4
Lagalwar, S.5
-
20
-
-
3242749074
-
Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology
-
Rissman RA, Poon WW, Blurton-Jones M, Oddo S, Torp R, et al. (2004) Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology. J Clin Invest 114: 121-130.
-
(2004)
J Clin Invest
, vol.114
, pp. 121-130
-
-
Rissman, R.A.1
Poon, W.W.2
Blurton-Jones, M.3
Oddo, S.4
Torp, R.5
-
21
-
-
67349191008
-
Truncated tau at D421 is associated with neurodegeneration and tangle formation in the brain of Alzheimer transgenic models
-
Zhang Q, Zhang X, Sun A, (2009) Truncated tau at D421 is associated with neurodegeneration and tangle formation in the brain of Alzheimer transgenic models. Acta Neuropathol 117: 687-697.
-
(2009)
Acta Neuropathol
, vol.117
, pp. 687-697
-
-
Zhang, Q.1
Zhang, X.2
Sun, A.3
-
22
-
-
77951540816
-
Caspase activation precedes and leads to tangles
-
de Calignon A, Fox LM, Pitstick R, Carlson GA, Bacskai BJ, et al. (2010) Caspase activation precedes and leads to tangles. Nature 464: 1201-1204.
-
(2010)
Nature
, vol.464
, pp. 1201-1204
-
-
de Calignon, A.1
Fox, L.M.2
Pitstick, R.3
Carlson, G.A.4
Bacskai, B.J.5
-
23
-
-
57449090951
-
Cerebral amyloid angiopathy and parenchymal amyloid deposition in transgenic mice expressing the Danish mutant form of human BRI2
-
Vidal R, Barbeito AG, Miravalle L, Ghetti B, (2009) Cerebral amyloid angiopathy and parenchymal amyloid deposition in transgenic mice expressing the Danish mutant form of human BRI2. Brain Pathol 19: 58-68.
-
(2009)
Brain Pathol
, vol.19
, pp. 58-68
-
-
Vidal, R.1
Barbeito, A.G.2
Miravalle, L.3
Ghetti, B.4
-
24
-
-
77950460827
-
Pathology of a Transgenic Mouse Expressing Human P301S Tau
-
Murrell JR, Gnezda AG, Green A, Greally J, Grahame N, et al. (2006) Pathology of a Transgenic Mouse Expressing Human P301S Tau. Brain Pathol 16: S44.
-
(2006)
Brain Pathol
, vol.16
-
-
Murrell, J.R.1
Gnezda, A.G.2
Green, A.3
Greally, J.4
Grahame, N.5
-
26
-
-
38149140232
-
Expression of a mutant form of the ferritin light chain gene induces neurodegeneration and iron overload in transgenic mice
-
Vidal R, Miravalle L, Gao X, Barbeito AG, Baraibar MA, et al. (2008) Expression of a mutant form of the ferritin light chain gene induces neurodegeneration and iron overload in transgenic mice. J Neurosci 28: 60-67.
-
(2008)
J Neurosci
, vol.28
, pp. 60-67
-
-
Vidal, R.1
Miravalle, L.2
Gao, X.3
Barbeito, A.G.4
Baraibar, M.A.5
-
27
-
-
84863201651
-
The Psen1-L166P-knock-in mutation leads to amyloid deposition in human wild-type amyloid precursor protein YAC transgenic mice
-
Vidal R, Sammeta N, Garringer HJ, Sambamurti K, Miravalle L, et al. (2012) The Psen1-L166P-knock-in mutation leads to amyloid deposition in human wild-type amyloid precursor protein YAC transgenic mice. FASEB J 26: 2899-2910.
-
(2012)
FASEB J
, vol.26
, pp. 2899-2910
-
-
Vidal, R.1
Sammeta, N.2
Garringer, H.J.3
Sambamurti, K.4
Miravalle, L.5
-
28
-
-
0036850725
-
Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein
-
Allen B, Ingram E, Takao M, Smith MJ, Jakes R, et al. (2002) Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein. J Neurosci 22: 9340-9351.
-
(2002)
J Neurosci
, vol.22
, pp. 9340-9351
-
-
Allen, B.1
Ingram, E.2
Takao, M.3
Smith, M.J.4
Jakes, R.5
-
29
-
-
0036904519
-
Assembly of tau in transgenic animals expressing P301L tau: alteration of phosphorylation and solubility
-
Sahara N, Lewis J, DeTure M, McGowan E, Dickson DW, et al. (2002) Assembly of tau in transgenic animals expressing P301L tau: alteration of phosphorylation and solubility. J Neurochem 83: 1498-1508.
-
(2002)
J Neurochem
, vol.83
, pp. 1498-1508
-
-
Sahara, N.1
Lewis, J.2
DeTure, M.3
McGowan, E.4
Dickson, D.W.5
-
30
-
-
65649154118
-
Abnormal iron metabolism and oxidative stress in mice expressing a mutant form of the ferritin light polypeptide gene
-
Barbeito AG, Garringer HJ, Baraibar MA, Gao X, Arredondo M, et al. (2009) Abnormal iron metabolism and oxidative stress in mice expressing a mutant form of the ferritin light polypeptide gene. J Neurochem 109: 1067-1078.
-
(2009)
J Neurochem
, vol.109
, pp. 1067-1078
-
-
Barbeito, A.G.1
Garringer, H.J.2
Baraibar, M.A.3
Gao, X.4
Arredondo, M.5
-
31
-
-
78049506839
-
Danish dementia mice suggest that loss of function and not the amyloid cascade causes synaptic plasticity and memory deficits
-
Tamayev R, Matsuda S, Fà M, Arancio O, D'Adamio L, (2010) Danish dementia mice suggest that loss of function and not the amyloid cascade causes synaptic plasticity and memory deficits. Proc Natl Acad Sci USA 107: 20822-20827.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 20822-20827
-
-
Tamayev, R.1
Matsuda, S.2
Fà, M.3
Arancio, O.4
D'Adamio, L.5
-
32
-
-
0347093672
-
Expression of BRI, the normal precursor of the amyloid protein of familial British dementia, in human brain
-
Akiyama H, Kondo H, Arai T, Ikeda K, Kato M, et al. (2004) Expression of BRI, the normal precursor of the amyloid protein of familial British dementia, in human brain. Acta Neuropathol 107: 53-58.
-
(2004)
Acta Neuropathol
, vol.107
, pp. 53-58
-
-
Akiyama, H.1
Kondo, H.2
Arai, T.3
Ikeda, K.4
Kato, M.5
-
33
-
-
0025987048
-
Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment
-
Terry R D, Masliah E, Salmon D P, Butters N, DeTeresa R, et al. (1991) Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment. Ann Neurol 30: 572-580.
-
(1991)
Ann Neurol
, vol.30
, pp. 572-580
-
-
Terry, R.D.1
Masliah, E.2
Salmon, D.P.3
Butters, N.4
DeTeresa, R.5
-
34
-
-
0030872413
-
Loss of the presynaptic vesicle protein synaptophysin in hippocampus correlates with cognitive decline in Alzheimer disease
-
Sze C-I, Troncoso JC, Kawas C, Mouton P, Price DL, et al. (1997) Loss of the presynaptic vesicle protein synaptophysin in hippocampus correlates with cognitive decline in Alzheimer disease. J Neuropathol Exp Neurol 56: 933-944.
-
(1997)
J Neuropathol Exp Neurol
, vol.56
, pp. 933-944
-
-
Sze, C.-I.1
Troncoso, J.C.2
Kawas, C.3
Mouton, P.4
Price, D.L.5
-
35
-
-
7044220336
-
Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches
-
Tsai J, Grutzendler J, Duff K, Gan WB, (2004) Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches. Nat Neurosci 7: 1181-1183.
-
(2004)
Nat Neurosci
, vol.7
, pp. 1181-1183
-
-
Tsai, J.1
Grutzendler, J.2
Duff, K.3
Gan, W.B.4
-
36
-
-
23444448170
-
Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy
-
Spires TL, Meyer-Luehmann M, Stern EA, McLean PJ, Skoch J, et al. (2005) Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy. J Neurosci 25: 7278-7287.
-
(2005)
J Neurosci
, vol.25
, pp. 7278-7287
-
-
Spires, T.L.1
Meyer-Luehmann, M.2
Stern, E.A.3
McLean, P.J.4
Skoch, J.5
-
37
-
-
59749104724
-
Widespread changes in dendritic spines in a model of Alzheimer's disease
-
Knafo S, Alonso-Nanclares L, Gonzalez-Soriano J, Merino-Serrais P, Fernaud-Espinosa I, et al. (2009) Widespread changes in dendritic spines in a model of Alzheimer's disease. Cereb Cortex 19: 586-92.
-
(2009)
Cereb Cortex
, vol.19
, pp. 586-592
-
-
Knafo, S.1
Alonso-Nanclares, L.2
Gonzalez-Soriano, J.3
Merino-Serrais, P.4
Fernaud-Espinosa, I.5
-
38
-
-
33845565678
-
Spatial relationship between synapse loss and β-amyloid deposition in Tg2576 mice
-
Dong H, Martin MV, Chambers S, Csernansky JG, (2007) Spatial relationship between synapse loss and β-amyloid deposition in Tg2576 mice. J Comp Neurol 500: 311-321.
-
(2007)
J Comp Neurol
, vol.500
, pp. 311-321
-
-
Dong, H.1
Martin, M.V.2
Chambers, S.3
Csernansky, J.G.4
-
39
-
-
0035943436
-
Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils
-
Götz J, Chen F, van Dorpe J, Nitsch RM, (2001) Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils. Science 293: 1491-1495.
-
(2001)
Science
, vol.293
, pp. 1491-1495
-
-
Götz, J.1
Chen, F.2
van Dorpe, J.3
Nitsch, R.M.4
-
40
-
-
17944382037
-
Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP
-
Lewis J, Dickson DW, Lin WL, Chisholm L, Corral A, et al. (2001) Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP. Science 293: 1487-1491.
-
(2001)
Science
, vol.293
, pp. 1487-1491
-
-
Lewis, J.1
Dickson, D.W.2
Lin, W.L.3
Chisholm, L.4
Corral, A.5
-
41
-
-
77952418165
-
Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease
-
Coomaraswamy J, Kilger E, Wölfing H, Schäfer C, Kaeser SA, et al. (2010) Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease. Proc Natl Acad Sci USA 107: 7969-7974.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 7969-7974
-
-
Coomaraswamy, J.1
Kilger, E.2
Wölfing, H.3
Schäfer, C.4
Kaeser, S.A.5
-
42
-
-
77957345679
-
Aβ accelerates the spatiotemporal progression of tau pathology and augments tau amyloidosis in an Alzheimer mouse model
-
Hurtado DE, Molina-Porcel L, Iba M, Aboagye AK, Paul SM, et al. (2010) Aβ accelerates the spatiotemporal progression of tau pathology and augments tau amyloidosis in an Alzheimer mouse model. Am J Pathol 177: 1977-1988.
-
(2010)
Am J Pathol
, vol.177
, pp. 1977-1988
-
-
Hurtado, D.E.1
Molina-Porcel, L.2
Iba, M.3
Aboagye, A.K.4
Paul, S.M.5
-
43
-
-
67349087945
-
Misfolded tau protein and disease modifying pathways in transgenic rodent models of human tauopathies
-
Zilka N, Korenova M, Novak M, (2009) Misfolded tau protein and disease modifying pathways in transgenic rodent models of human tauopathies. Acta Neuropathol 118: 71-86.
-
(2009)
Acta Neuropathol
, vol.118
, pp. 71-86
-
-
Zilka, N.1
Korenova, M.2
Novak, M.3
-
44
-
-
38749144389
-
Analysis of tau phosphorylation and truncation in a mouse model of human tauopathy
-
Delobel P, Lavenir I, Fraser G, Ingram E, Holzer M, et al. (2008) Analysis of tau phosphorylation and truncation in a mouse model of human tauopathy. Am J Pathol 172: 123-131.
-
(2008)
Am J Pathol
, vol.172
, pp. 123-131
-
-
Delobel, P.1
Lavenir, I.2
Fraser, G.3
Ingram, E.4
Holzer, M.5
-
45
-
-
38549120646
-
In vivo imaging reveals dissociation between caspase activation and acute neuronal death in tangle-bearing neurons
-
Spires-Jones TL, de Calignon A, Matsui T, Zehr C, Pitstick R, et al. (2008) In vivo imaging reveals dissociation between caspase activation and acute neuronal death in tangle-bearing neurons. J Neurosci 28: 862-867.
-
(2008)
J Neurosci
, vol.28
, pp. 862-867
-
-
Spires-Jones, T.L.1
de Calignon, A.2
Matsui, T.3
Zehr, C.4
Pitstick, R.5
-
46
-
-
44449098256
-
Microglial activation in brain lesions with tau deposits: comparison of human tauopathies and tau transgenic mice TgTauP301L
-
Sasaki A, Kawarabayashi T, Murakami T, Matsubara E, Ikeda M, et al. (2008) Microglial activation in brain lesions with tau deposits: comparison of human tauopathies and tau transgenic mice TgTauP301L. Brain Res 1214: 159-168.
-
(2008)
Brain Res
, vol.1214
, pp. 159-168
-
-
Sasaki, A.1
Kawarabayashi, T.2
Murakami, T.3
Matsubara, E.4
Ikeda, M.5
-
47
-
-
79955871342
-
Presence of reactive microglia and neuroinflammatory mediators in a case of frontotemporal dementia with P301S mutation
-
Bellucci A, Bugiani O, Ghetti B, Spillantini MG, (2011) Presence of reactive microglia and neuroinflammatory mediators in a case of frontotemporal dementia with P301S mutation. Neurodegener Dis 8: 221-829.
-
(2011)
Neurodegener Dis
, vol.8
, pp. 221-829
-
-
Bellucci, A.1
Bugiani, O.2
Ghetti, B.3
Spillantini, M.G.4
-
48
-
-
33846538660
-
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
-
Yoshiyama Y, Higuchi M, Zhang B, Huang SM, Iwata N, et al. (2007) Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model. Neuron 53: 337-351.
-
(2007)
Neuron
, vol.53
, pp. 337-351
-
-
Yoshiyama, Y.1
Higuchi, M.2
Zhang, B.3
Huang, S.M.4
Iwata, N.5
-
49
-
-
19944432508
-
Accumulation of filamentous tau in the cerebral cortex of human tau R406W transgenic mice
-
Ikeda M, Shoji M, Kawarai T, Kawarabayashi T, Matsubara E, et al. (2005) Accumulation of filamentous tau in the cerebral cortex of human tau R406W transgenic mice. Am J Pathol 166: 521-531.
-
(2005)
Am J Pathol
, vol.166
, pp. 521-531
-
-
Ikeda, M.1
Shoji, M.2
Kawarai, T.3
Kawarabayashi, T.4
Matsubara, E.5
-
50
-
-
79957653811
-
Intraneuronal APP, not free Aβ peptides in 3xTg-AD mice: implications for tau versus Aβ-mediated Alzheimer neurodegeneration
-
Winton MJ, Lee EB, Sun E, Wong MM, Leight S, et al. (2011) Intraneuronal APP, not free Aβ peptides in 3xTg-AD mice: implications for tau versus Aβ-mediated Alzheimer neurodegeneration. J Neurosci 31: 7691-7699.
-
(2011)
J Neurosci
, vol.31
, pp. 7691-7699
-
-
Winton, M.J.1
Lee, E.B.2
Sun, E.3
Wong, M.M.4
Leight, S.5
-
51
-
-
1642578930
-
Characterisation of cytoskeletal abnormalities in mice transgenic for wild-type human tau and familial Alzheimer's disease mutants of APP and presenilin-1
-
Boutajangout A, Authelet M, Blanchard V, Touchet N, Tremp G, et al. (2004) Characterisation of cytoskeletal abnormalities in mice transgenic for wild-type human tau and familial Alzheimer's disease mutants of APP and presenilin-1. Neurobiol Dis 15: 47-60.
-
(2004)
Neurobiol Dis
, vol.15
, pp. 47-60
-
-
Boutajangout, A.1
Authelet, M.2
Blanchard, V.3
Touchet, N.4
Tremp, G.5
-
52
-
-
0037450356
-
PDAPP; YFP double transgenic mice: a tool to study amyloid-beta associated changes in axonal, dendritic, and synaptic structures
-
Brendza RP, O'Brien C, Simmons K, McKeel DW, Bales KR, et al. (2003) PDAPP; YFP double transgenic mice: a tool to study amyloid-beta associated changes in axonal, dendritic, and synaptic structures. J Comp Neurol 456: 375-383.
-
(2003)
J Comp Neurol
, vol.456
, pp. 375-383
-
-
Brendza, R.P.1
O'Brien, C.2
Simmons, K.3
McKeel, D.W.4
Bales, K.R.5
-
53
-
-
5344277556
-
Deciphering the molecular basis of memory failure in Alzheimer's disease
-
Walsh DM, Selkoe DJ, (2004) Deciphering the molecular basis of memory failure in Alzheimer's disease. Neuron 44: 181-193.
-
(2004)
Neuron
, vol.44
, pp. 181-193
-
-
Walsh, D.M.1
Selkoe, D.J.2
-
54
-
-
0042697305
-
Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction
-
Oddo S, Caccamo A, Shepherd JD, Murphy MP, Golde TE, et al. (2003) Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron 39: 409-421.
-
(2003)
Neuron
, vol.39
, pp. 409-421
-
-
Oddo, S.1
Caccamo, A.2
Shepherd, J.D.3
Murphy, M.P.4
Golde, T.E.5
-
55
-
-
14644442872
-
Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice
-
Billings LM, Oddo S, Green KN, McGaugh JL, LaFerla FM, (2005) Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice. Neuron 45: 675-688.
-
(2005)
Neuron
, vol.45
, pp. 675-688
-
-
Billings, L.M.1
Oddo, S.2
Green, K.N.3
McGaugh, J.L.4
LaFerla, F.M.5
-
56
-
-
62649174753
-
Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques
-
Koffie RM, Meyer-Luehmann M, Hashimoto T, Adams KW, Mielke ML, et al. (2009) Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques. Proc Natl Acad Sci USA 106: 4012-4017.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 4012-4017
-
-
Koffie, R.M.1
Meyer-Luehmann, M.2
Hashimoto, T.3
Adams, K.W.4
Mielke, M.L.5
-
57
-
-
79957913270
-
Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice
-
Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Clos AL, Jackson GR, Kayed R, (2011) Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice. Mol Neurodegener 6: 39.
-
(2011)
Mol Neurodegener
, vol.6
, pp. 39
-
-
Lasagna-Reeves, C.A.1
Castillo-Carranza, D.L.2
Sengupta, U.3
Clos, A.L.4
Jackson, G.R.5
Kayed, R.6
-
58
-
-
23844491144
-
The familial dementia BRI2 gene binds the Alzheimer gene amyloid-beta precursor protein and inhibits amyloid-beta production
-
Matsuda S, Giliberto L, Matsuda Y, Davies P, McGowan E, et al. (2005) The familial dementia BRI2 gene binds the Alzheimer gene amyloid-beta precursor protein and inhibits amyloid-beta production. J Biol Chem 280: 28912-28916.
-
(2005)
J Biol Chem
, vol.280
, pp. 28912-28916
-
-
Matsuda, S.1
Giliberto, L.2
Matsuda, Y.3
Davies, P.4
McGowan, E.5
-
59
-
-
70849110420
-
Generation and initial characterization of FDD knock in mice
-
Giliberto L, Matsuda S, Vidal R, D'Adamio L, (2009) Generation and initial characterization of FDD knock in mice. PLoS One 4 (11) (): e7900.
-
(2009)
PLoS One
, vol.4
, Issue.11
-
-
Giliberto, L.1
Matsuda, S.2
Vidal, R.3
D'Adamio, L.4
-
60
-
-
78049490869
-
Memory deficits due to familial British dementia BRI2 mutation are caused by loss of BRI2 function rather than amyloidosis
-
Tamayev R, Giliberto L, Li W, d'Abramo C, Arancio O, et al. (2010) Memory deficits due to familial British dementia BRI2 mutation are caused by loss of BRI2 function rather than amyloidosis. J Neurosci 30: 14915-14924.
-
(2010)
J Neurosci
, vol.30
, pp. 14915-14924
-
-
Tamayev, R.1
Giliberto, L.2
Li, W.3
d'Abramo, C.4
Arancio, O.5
-
61
-
-
79958785727
-
APP heterozygosity averts memory deficit in knockin mice expressing the Danish dementia BRI2 mutant
-
Tamayev R, Matsuda S, Giliberto L, Arancio O, D'Adamio L, (2011) APP heterozygosity averts memory deficit in knockin mice expressing the Danish dementia BRI2 mutant. EMBO J 30: 2501-2509.
-
(2011)
EMBO J
, vol.30
, pp. 2501-2509
-
-
Tamayev, R.1
Matsuda, S.2
Giliberto, L.3
Arancio, O.4
D'Adamio, L.5
|