The molecular link between inefficient GluA2 Q/R site-RNA editing and TDP-43 pathology in motor neurons of sporadic amyotrophic lateral sclerosis patients

Brain Research

Volumn 1584, Issue , 2014, Pages 28-38

  Yamashita, Takenari ^a,b   Kwak, Shin ^a,b,c  

^a JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c INTERNATIONAL UNIVERSITY OF HEALTH AND WELFARE   (Japan)

Author keywords

Adenosine deaminase acting on; AMPA receptor; Amyotrophic lateral sclerosis (ALS); Calpain; GluA2; RNA 2 (ADAR2); RNA editing; TAR DNA binding protein of 43 kDa (TDP 43)

Indexed keywords

ADENOSINE; ADENOSINE DEAMINASE ACTING ON RNA 2; AMPA RECEPTOR; ARGININE; CALCIUM; CALPAIN; ENZYME; GLUA2 PROTEIN; GLUTAMINE; INOSINE; PROTEIN; TAR DNA BINDING PROTEIN; UNCLASSIFIED DRUG; ADAR2 PROTEIN, MOUSE; ADARB1 PROTEIN, HUMAN; ADENOSINE DEAMINASE; DNA BINDING PROTEIN; GLUTAMATE RECEPTOR IONOTROPIC, AMPA 2; PROTEIN TDP-43; RNA BINDING PROTEIN;

AMINO TERMINAL SEQUENCE; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CALCIUM TRANSPORT; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE PERMEABILITY; CELLULAR DISTRIBUTION; CHOLINERGIC NERVE CELL; DEATH; DOWN REGULATION; GENE TARGETING; HUMAN; KNOCKOUT MOUSE; MOTONEURON; NERVE CELL NECROSIS; NEUROLOGIC DISEASE; NONHUMAN; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RNA EDITING; SPINAL CORD; TDP 43 PROTEINOPATHY; ANIMAL; CELL DEATH; ENZYMOLOGY; GENETICS; METABOLISM; MOUSE; PATHOLOGY;

ADENOSINE DEAMINASE; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; CALPAIN; CELL DEATH; DNA-BINDING PROTEINS; HUMANS; MICE; MOTOR NEURONS; RECEPTORS, AMPA; RNA EDITING; RNA-BINDING PROTEINS; SPINAL CORD;

EID: 84907688040     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2013.12.011     Document Type: Article

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