Quantitation and localization of intracellular redox active metals by X-ray fluorescence microscopy in cortical neurons derived from APP and APLP2 knockout tissue

Metallomics

Volumn 6, Issue 10, 2014, Pages 1894-1904

  Ciccotosto, Giuseppe D ^a   James, Simon A ^b,c   Altissimo, Matteo ^d   Paterson, David ^b   Vogt, Stefan ^e   Lai, Barry ^e   De Jonge, Martin D ^b   Howard, Daryl L ^b   Bush, Ashley I ^f   Cappai, Roberto ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b AUSTRALIAN SYNCHROTRON   (Australia)

^c CSIRO   (Australia)

^d SINCROTRONE TRIESTE   (Italy)

^e ARGONNE NATIONAL LABORATORY   (United States)

^f UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; COPPER; FLUORESCENCE; FLUORESCENCE MICROSCOPY; GLYCOPROTEINS; METAL IONS; METALS; PHYSIOLOGY; REDOX REACTIONS; ZINC;

AMYLOID PRECURSOR PROTEINS; CORTICAL NEURONS; METAL BINDING SITES; METAL HOMEOSTASIS; PHYSIOLOGICAL ROLES; REDOX-ACTIVE METALS; SUBCELLULAR DISTRIBUTION; X-RAY FLUORESCENCE MICROSCOPY;

PROTEINS;

AMYLOID PRECURSOR LIKE PROTEIN 1; AMYLOID PRECURSOR PROTEIN; CALCIUM; COPPER; IRON; METALLOPROTEIN; UNCLASSIFIED DRUG; ZINC; APLP2 PROTEIN, MOUSE; METAL;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; BRAIN NERVE CELL; BRAIN SLICE; BRAIN TISSUE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GENE INACTIVATION; GENOTYPE; HOMEOSTASIS; IMAGE PROCESSING; KNOCKOUT MOUSE; MOUSE; NERVE CELL CULTURE; NONHUMAN; PROTEIN EXPRESSION; X RAY FLUORESCENCE; X RAY FLUORESCENCE MICROSCOPY; ANIMAL; BRAIN; C57BL MOUSE; CYTOLOGY; FLUORESCENCE MICROSCOPY; GENETICS; METABOLISM; NERVE CELL; OXIDATION REDUCTION REACTION; X RAY;

AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BRAIN; CALCIUM; COPPER; GENE KNOCKOUT TECHNIQUES; GENOTYPE; IRON; METALS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; NEURONS; OXIDATION-REDUCTION; X-RAYS; ZINC;

EID: 84907666974     PISSN: 17565901     EISSN: 1756591X     Source Type: Journal    
DOI: 10.1039/c4mt00176a     Document Type: Article

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