-
1
-
-
34548400209
-
Model fusion, the next phase in developing animal models for Parkinson's disease
-
Manning-Bog, A. B., & Langston, J. W. Model fusion, the next phase in developing animal models for Parkinson's disease. Neurotox. Res. 11, 219-240 (2007).
-
(2007)
Neurotox. Res.
, vol.11
, pp. 219-240
-
-
Manning-Bog, A.B.1
Langston, J.W.2
-
2
-
-
77956226230
-
Gene-environment interactions in Parkinson's disease and other forms of parkinsonism
-
doi:10.1016/j.neuro.2010.04.007
-
Vance, J. M., Ali, S., Bradley, W. G., Singer, C., & Di Monte, D. A. Gene-environment interactions in Parkinson's disease and other forms of parkinsonism. Neurotoxicology. 31, 598-602, doi:10.1016/j.neuro.2010.04.007 (2010).
-
(2010)
Neurotoxicology.
, vol.31
, pp. 598-602
-
-
Vance, J.M.1
Ali, S.2
Bradley, W.G.3
Singer, C.4
Di Monte, D.A.5
-
3
-
-
0021280826
-
Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine in mice
-
Heikkila, R. E., Hess, A., & Duvoisin, R. C. Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine in mice. Science. 224, 1451-1453 (1984).
-
(1984)
Science.
, vol.224
, pp. 1451-1453
-
-
Heikkila, R.E.1
Hess, A.2
Duvoisin, R.C.3
-
4
-
-
84868577749
-
Differential contribution of lipoxygenase isozymes to nigrostriatal vulnerability
-
doi:10.1016/j.neuroscience.2012.10.009
-
Chou, V. P., Holman, T. R., & Manning-Bog, A. B. Differential contribution of lipoxygenase isozymes to nigrostriatal vulnerability. Neuroscience. 228, 73-82, doi:10.1016/j.neuroscience.2012.10.009 (2013).
-
(2013)
Neuroscience.
, vol.228
, pp. 73-82
-
-
Chou, V.P.1
Holman, T.R.2
Manning-Bog, A.B.3
-
5
-
-
33646177187
-
Baicalein is a potent in vitro inhibitor against both reticulocyte 15-human and platelet 12-human lipoxygenases
-
doi:10.1016/j.bmc.2006.01.057
-
Deschamps, J. D., Kenyon, V. A., & Holman, T. R. Baicalein is a potent in vitro inhibitor against both reticulocyte 15-human and platelet 12-human lipoxygenases. Bioorg. Med. Chem. 14, 4295-4301, doi:10.1016/j.bmc.2006.01.057 (2006).
-
(2006)
Bioorg. Med. Chem.
, vol.14
, pp. 4295-4301
-
-
Deschamps, J.D.1
Kenyon, V.A.2
Holman, T.R.3
-
6
-
-
84860488264
-
Integration of pro-inflammatory cytokines, 12-lipoxygenase and NOX-1 in pancreatic islet beta cell dysfunction
-
doi:10.1016/j.mce.2012.03.004
-
Weaver, J. R. et al. Integration of pro-inflammatory cytokines, 12-lipoxygenase and NOX-1 in pancreatic islet beta cell dysfunction. Mol. Cell Endocrinol.358, 88-95, doi:10.1016/j.mce.2012.03.004 (2012).
-
(2012)
Mol. Cell Endocrinol.
, vol.358
, pp. 88-95
-
-
Weaver, J.R.1
-
7
-
-
84873411666
-
Inhibition of 12/15-lipoxygenase as therapeutic strategy to treat stroke
-
doi:10.1002/ana.23734
-
Yigitkanli, K. et al. Inhibition of 12/15-lipoxygenase as therapeutic strategy to treat stroke. Ann. Neurol. 73, 129-135, doi:10.1002/ana.23734 (2013).
-
(2013)
Ann. Neurol.
, vol.73
, pp. 129-135
-
-
Yigitkanli, K.1
-
8
-
-
40549137151
-
Novel lipoxygenase inhibitors as neuroprotective reagents
-
doi:10.1002/jnr.21543
-
van Leyen, K. et al. Novel lipoxygenase inhibitors as neuroprotective reagents. J Neurosci. Res. 86, 904-909, doi:10.1002/jnr.21543 (2008).
-
(2008)
J Neurosci. Res.
, vol.86
, pp. 904-909
-
-
van Leyen, K.1
-
9
-
-
79551473183
-
5-lipoxygenase as an endogenous modulator of amyloid beta formation in vivo
-
doi:10.1002/ana.22234
-
Chu, J., & Pratico, D. 5-lipoxygenase as an endogenous modulator of amyloid beta formation in vivo. Ann. Neurol. 69, 34-46, doi:10.1002/ana.22234 (2011).
-
(2011)
Ann. Neurol.
, vol.69
, pp. 34-46
-
-
Chu, J.1
Pratico, D.2
-
10
-
-
0020680904
-
Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis
-
Langston, J. W., Ballard, P., Tetrud, J. W., & Irwin, I. Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis. Science. 219, 979-980 (1983).
-
(1983)
Science.
, vol.219
, pp. 979-980
-
-
Langston, J.W.1
Ballard, P.2
Tetrud, J.W.3
Irwin, I.4
-
11
-
-
84860615324
-
Neurotoxin-based models of Parkinson's disease
-
doi:10.1016/j.neuroscience.2011.10.057
-
Bove, J., & Perier, C. Neurotoxin-based models of Parkinson's disease. Neuroscience. 211, 51-76, doi:10.1016/j.neuroscience.2011.10.057 (2012).
-
(2012)
Neuroscience.
, vol.211
, pp. 51-76
-
-
Bove, J.1
Perier, C.2
-
12
-
-
80052809265
-
Neuroprotective effects of creatine
-
doi:10.1007/s00726-011-0851-0
-
Beal, M. F. Neuroprotective effects of creatine. Amino Acids. 40, 1305-1313, doi:10.1007/s00726-011-0851-0 (2011).
-
(2011)
Amino Acids.
, vol.40
, pp. 1305-1313
-
-
Beal, M.F.1
-
13
-
-
84858648303
-
Animal models of Parkinson's disease
-
doi:10.1016/S1353-8020(11)70057-8
-
Jackson-Lewis, V., Blesa, J., & Przedborski, S. Animal models of Parkinson's disease. Parkinsonism Relat. Disord. 18 Suppl 1, S183-185, doi:10.1016/S1353-8020(11)70057-8 (2012).
-
(2012)
Parkinsonism Relat. Disord.
, vol.18
, Issue.SUPPL. 1
-
-
Jackson-Lewis, V.1
Blesa, J.2
Przedborski, S.3
-
14
-
-
0141741347
-
Parkinson's disease: Mechanisms and models
-
Dauer, W., & Przedborski, S. Parkinson's disease: mechanisms and models. Neuron. 39, 889-909 (2003).
-
(2003)
Neuron.
, vol.39
, pp. 889-909
-
-
Dauer, W.1
Przedborski, S.2
-
15
-
-
0037713529
-
Apoptosis inducing factor and PARP-mediated injury in the MPTP mouse model of Parkinson's disease
-
Wang, H., Shimoji, M., Yu, S. W., Dawson, T. M., & Dawson, V. L. Apoptosis inducing factor and PARP-mediated injury in the MPTP mouse model of Parkinson's disease. Ann. N.Y. Acad. Sci. 991, 132-139 (2003).
-
(2003)
Ann. N.Y. Acad. Sci.
, vol.991
, pp. 132-139
-
-
Wang, H.1
Shimoji, M.2
Yu, S.W.3
Dawson, T.M.4
Dawson, V.L.5
-
16
-
-
0035960066
-
Mouse model of Parkinsonism: A comparison between subacute MPTP and chronic MPTP/probenecid treatment
-
Petroske, E., Meredith, G. E., Callen, S., Totterdell, S., & Lau, Y. S. Mouse model of Parkinsonism: a comparison between subacute MPTP and chronic MPTP/probenecid treatment. Neuroscience. 106, 589-601 (2001).
-
(2001)
Neuroscience.
, vol.106
, pp. 589-601
-
-
Petroske, E.1
Meredith, G.E.2
Callen, S.3
Totterdell, S.4
Lau, Y.S.5
-
17
-
-
0035091767
-
The parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): A technical review of its utility and safety
-
Przedborski, S. et al. The parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a technical review of its utility and safety. J. Neurochem. 76, 1265-1274 (2001).
-
(2001)
J. Neurochem.
, vol.76
, pp. 1265-1274
-
-
Przedborski, S.1
-
18
-
-
84863229879
-
Mitochondrial permeability transition pore component cyclophilin D distinguishes nigrostriatal dopaminergic death paradigms in the MPTP mouse model of Parkinson's disease
-
doi:10.1089/ars.2010.3849
-
Thomas, B. et al. Mitochondrial permeability transition pore component cyclophilin D distinguishes nigrostriatal dopaminergic death paradigms in the MPTP mouse model of Parkinson's disease. Antioxid. Redox. Signal. 16, 855-868, doi:10.1089/ars.2010.3849 (2012).
-
(2012)
Antioxid. Redox. Signal.
, vol.16
, pp. 855-868
-
-
Thomas, B.1
-
19
-
-
0022480636
-
The influence of dose and dosing interval on MPTP-induced dopaminergic neurotoxicity in mice
-
Sonsalla, P. K., & Heikkila, R. E. The influence of dose and dosing interval on MPTP-induced dopaminergic neurotoxicity in mice. Eur. J. Pharmacol. 129, 339-345 (1986).
-
(1986)
Eur. J. Pharmacol.
, vol.129
, pp. 339-345
-
-
Sonsalla, P.K.1
Heikkila, R.E.2
-
20
-
-
0034114557
-
Relationship among nigrostriatal denervation, parkinsonism, and dyskinesias in the MPTP primate model
-
Di Monte, D. A. et al. Relationship among nigrostriatal denervation, parkinsonism, and dyskinesias in the MPTP primate model. Mov. Disord. 15, 459-466 (2000).
-
(2000)
Mov. Disord.
, vol.15
, pp. 459-466
-
-
Di Monte, D.A.1
-
21
-
-
84855568952
-
Apoptosis signal-regulating kinase 1 mediates MPTP toxicity and regulates glial activation
-
doi:10.1371/journal.pone.0029935
-
Lee, K. W. et al. Apoptosis signal-regulating kinase 1 mediates MPTP toxicity and regulates glial activation. PLoS One. 7, e29935, doi:10.1371/journal.pone.0029935 (2012).
-
(2012)
PLoS One.
, vol.7
-
-
Lee, K.W.1
-
22
-
-
34347259269
-
Protocol for the MPTP mouse model of Parkinson's disease
-
doi:10.1038/nprot.2006.342
-
Jackson-Lewis, V., & Przedborski, S. Protocol for the MPTP mouse model of Parkinson's disease. Nat. Protoc. 2, 141-151, doi:10.1038/nprot.2006.342 (2007).
-
(2007)
Nat. Protoc.
, vol.2
, pp. 141-151
-
-
Jackson-Lewis, V.1
Przedborski, S.2
-
23
-
-
0036789082
-
Increased vulnerability of dopaminergic neurons in MPTP-lesioned interleukin-6 deficient mice
-
Bolin, L. M., Strycharska-Orczyk, I., Murray, R., Langston, J. W., & Di Monte, D. Increased vulnerability of dopaminergic neurons in MPTP-lesioned interleukin-6 deficient mice. J. Neurochem. 83, 167-175 (2002).
-
(2002)
J. Neurochem.
, vol.83
, pp. 167-175
-
-
Bolin, L.M.1
Strycharska-Orczyk, I.2
Murray, R.3
Langston, J.W.4
Di Monte, D.5
-
24
-
-
34447621054
-
Increased vulnerability of nigrostriatal terminals in DJ-1-deficient mice is mediated by the dopamine transporter
-
doi:10.1016/j.nbd.2007.03.014
-
Manning-Bog, A. B. et al. Increased vulnerability of nigrostriatal terminals in DJ-1-deficient mice is mediated by the dopamine transporter. Neurobiol. Dis.27, 141-150, doi:10.1016/j.nbd.2007.03.014 (2007).
-
(2007)
Neurobiol. Dis.
, vol.27
, pp. 141-150
-
-
Manning-Bog, A.B.1
-
25
-
-
0035798302
-
Nicotine administration reduces striatal MPP+ levels in mice
-
Quik, M., & Di Monte, D. A. Nicotine administration reduces striatal MPP+ levels in mice. Brain Res. 917, 219-224 (2001).
-
(2001)
Brain Res.
, vol.917
, pp. 219-224
-
-
Quik, M.1
Di Monte, D.A.2
-
26
-
-
0021137683
-
Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism
-
Markey, S. P., Johannessen, J. N., Chiueh, C. C., Burns, R. S., & Herkenham, M. A. Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism. Nature. 311, 464-467 (1984).
-
(1984)
Nature.
, vol.311
, pp. 464-467
-
-
Markey, S.P.1
Johannessen, J.N.2
Chiueh, C.C.3
Burns, R.S.4
Herkenham, M.A.5
-
27
-
-
0021224694
-
Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors
-
Heikkila, R. E., Manzino, L., Cabbat, F. S., & Duvoisin, R. C. Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors. Nature. 311, 467-469 (1984).
-
(1984)
Nature.
, vol.311
, pp. 467-469
-
-
Heikkila, R.E.1
Manzino, L.2
Cabbat, F.S.3
Duvoisin, R.C.4
-
28
-
-
0023848664
-
MPTP in mice: Treatment, distribution and possible source of contamination
-
Crampton, J. M., Runice, C. E., Doyle, T. J., Lau, Y. S., & Wilson, J. A. MPTP in mice: treatment, distribution and possible source of contamination. Life Sci. 42, 73-78 (1988).
-
(1988)
Life Sci.
, vol.42
, pp. 73-78
-
-
Crampton, J.M.1
Runice, C.E.2
Doyle, T.J.3
Lau, Y.S.4
Wilson, J.A.5
-
29
-
-
0024095706
-
Recommended safe practices for using the neurotoxin MPTP in animal experiments
-
Yang, S. C., Markey, S. P., Bankiewicz, K. S., London, W. T., & Lunn, G. Recommended safe practices for using the neurotoxin MPTP in animal experiments. Lab. Anim. Sci. 38, 563-567 (1988).
-
(1988)
Lab. Anim. Sci.
, vol.38
, pp. 563-567
-
-
Yang, S.C.1
Markey, S.P.2
Bankiewicz, K.S.3
London, W.T.4
Lunn, G.5
-
30
-
-
21444451858
-
MPTP treatment in mice does not transmit and cause Parkinsonian neurotoxicity in non-treated cagemates through close contact
-
doi:10.1016/j.neures.2005.04.010
-
Lau, Y. S., Novikova, L., & Roels, C. MPTP treatment in mice does not transmit and cause Parkinsonian neurotoxicity in non-treated cagemates through close contact. Neuroscience research. 52, 371-378, doi:10.1016/j.neures.2005.04.010 (2005).
-
(2005)
Neuroscience research.
, vol.52
, pp. 371-378
-
-
Lau, Y.S.1
Novikova, L.2
Roels, C.3
-
31
-
-
0023214348
-
Central hypothermic effects of some analogues of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 1-methyl-4-phenylpyridinium ion (MPP+)
-
Satoh, N. et al. Central hypothermic effects of some analogues of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 1-methyl-4-phenylpyridinium ion (MPP+). Neurosci. Lett. 80, 100-105 (1987).
-
(1987)
Neurosci. Lett.
, vol.80
, pp. 100-105
-
-
Satoh, N.1
-
32
-
-
37249011444
-
Behavioral and histopathological consequences of paraquat intoxication in mice: Effects of alpha-synuclein over-expression
-
doi:10.1002/syn.20456
-
Fernagut, P. O. et al. Behavioral and histopathological consequences of paraquat intoxication in mice: effects of alpha-synuclein over-expression. Synapse.61, 991-1001, doi:10.1002/syn.20456 (2007).
-
(2007)
Synapse.
, vol.61
, pp. 991-1001
-
-
Fernagut, P.O.1
-
33
-
-
0038334899
-
Alpha-synuclein overexpression protects against paraquat-induced neurodegeneration
-
Manning-Bog, A. B., McCormack, A. L., Purisai, M. G., Bolin, L. M., & Di Monte, D. A. Alpha-synuclein overexpression protects against paraquat-induced neurodegeneration. J. Neurosci. 23, 3095-3099 (2003).
-
(2003)
J. Neurosci.
, vol.23
, pp. 3095-3099
-
-
Manning-Bog, A.B.1
McCormack, A.L.2
Purisai, M.G.3
Bolin, L.M.4
Di Monte, D.A.5
-
34
-
-
0036245056
-
Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice
-
doi:10.1006/exnr.2002.7882
-
Richfield, E. K. et al. Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice. Exp. Neurol. 175, 35-48, doi:10.1006/exnr.2002.7882 (2002).
-
(2002)
Exp. Neurol.
, vol.175
, pp. 35-48
-
-
Richfield, E.K.1
-
35
-
-
79551619339
-
Resistance to MPTP-neurotoxicity in alpha-synuclein knockout mice is complemented by human alpha-synuclein and associated with increased beta-synuclein and Akt activation
-
doi:10.1371/journal.pone.0016706
-
Thomas, B. et al. Resistance to MPTP-neurotoxicity in alpha-synuclein knockout mice is complemented by human alpha-synuclein and associated with increased beta-synuclein and Akt activation. PloS one. 6, e16706, doi:10.1371/journal.pone.0016706 (2011).
-
(2011)
PloS one.
, vol.6
-
-
Thomas, B.1
-
36
-
-
0035870598
-
Strain-dependent susceptibility to MPTP and MPP(+)-induced parkinsonism is determined by glia
-
Smeyne, M., Goloubeva, O., & Smeyne, R. J. Strain-dependent susceptibility to MPTP and MPP(+)-induced parkinsonism is determined by glia. Glia. 34, 73-80 (2001).
-
(2001)
Glia.
, vol.34
, pp. 73-80
-
-
Smeyne, M.1
Goloubeva, O.2
Smeyne, R.J.3
-
37
-
-
0033562891
-
Differential strain susceptibility following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration acts in an autosomal dominant fashion: Quantitative analysis in seven strains of Mus musculus
-
Hamre, K., Tharp, R., Poon, K., Xiong, X., & Smeyne, R. J. Differential strain susceptibility following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration acts in an autosomal dominant fashion: quantitative analysis in seven strains of Mus musculus. Brain Res. 828, 91-103 (1999).
-
(1999)
Brain Res.
, vol.828
, pp. 91-103
-
-
Hamre, K.1
Tharp, R.2
Poon, K.3
Xiong, X.4
Smeyne, R.J.5
-
38
-
-
0033749345
-
MPTP susceptibility in the mouse: Behavioral, neurochemical, and histological analysis of gender and strain differences
-
Sedelis, M. et al. MPTP susceptibility in the mouse: behavioral, neurochemical, and histological analysis of gender and strain differences. Behav. Genet. 30, 171-182 (2000).
-
(2000)
Behav. Genet.
, vol.30
, pp. 171-182
-
-
Sedelis, M.1
-
39
-
-
34848855366
-
Response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) differs in mouse strains and reveals a divergence in JNK signaling and COX-2 induction prior to loss of neurons in the substantia nigra pars compacta
-
doi:10.1016/j.brainres.2007.07.067
-
Boyd, J. D. et al. Response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) differs in mouse strains and reveals a divergence in JNK signaling and COX-2 induction prior to loss of neurons in the substantia nigra pars compacta. Brain Res. 1175, 107-116, doi:10.1016/j.brainres.2007.07.067 (2007).
-
(2007)
Brain Res.
, vol.1175
, pp. 107-116
-
-
Boyd, J.D.1
-
40
-
-
69249216450
-
Gender differences on MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity in C57BL/6 mice
-
doi:10.1016/j.mce.2009.07.011
-
Ookubo, M., Yokoyama, H., Kato, H., & Araki, T. Gender differences on MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity in C57BL/6 mice. Molecular and cellular endocrinology. 311, 62-68, doi:10.1016/j.mce.2009.07.011 (2009).
-
(2009)
Molecular and cellular endocrinology.
, vol.311
, pp. 62-68
-
-
Ookubo, M.1
Yokoyama, H.2
Kato, H.3
Araki, T.4
-
41
-
-
9444251087
-
Estrogen and neuroprotection: Higher constitutive expression of glutaredoxin in female mice offers protection against MPTP-mediated neurodegeneration
-
doi:10.1096/fj.03-1075fje
-
Kenchappa, R. S., Diwakar, L., Annepu, J., & Ravindranath, V. Estrogen and neuroprotection: higher constitutive expression of glutaredoxin in female mice offers protection against MPTP-mediated neurodegeneration. FASEB J. 18, 1102-1104, doi:10.1096/fj.03-1075fje (2004).
-
(2004)
FASEB J.
, vol.18
, pp. 1102-1104
-
-
Kenchappa, R.S.1
Diwakar, L.2
Annepu, J.3
Ravindranath, V.4
-
42
-
-
0028784523
-
Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
-
Jackson-Lewis, V., Jakowec, M., Burke, R. E., & Przedborski, S. Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Neurodegeneration. 4, 257-269 (1995).
-
(1995)
Neurodegeneration.
, vol.4
, pp. 257-269
-
-
Jackson-Lewis, V.1
Jakowec, M.2
Burke, R.E.3
Przedborski, S.4
-
43
-
-
0023186383
-
Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion on activities of the enzymes in the electron transport system in mouse brain
-
Mizuno, Y., Sone, N., & Saitoh, T. Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion on activities of the enzymes in the electron transport system in mouse brain. J. Neurochem. 48, 1787-1793 (1987).
-
(1987)
J. Neurochem.
, vol.48
, pp. 1787-1793
-
-
Mizuno, Y.1
Sone, N.2
Saitoh, T.3
-
44
-
-
0023093745
-
MPTP, MPP+ and mitochondrial function
-
Nicklas, W. J., Youngster, S. K., Kindt, M. V., & Heikkila, R. E. MPTP, MPP+ and mitochondrial function. Life Sci. 40, 721-729 (1987).
-
(1987)
Life Sci.
, vol.40
, pp. 721-729
-
-
Nicklas, W.J.1
Youngster, S.K.2
Kindt, M.V.3
Heikkila, R.E.4
-
45
-
-
0021810979
-
Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine
-
Nicklas, W. J., Vyas, I., & Heikkila, R. E. Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine. Life Sci. 36, 2503-2508 (1985).
-
(1985)
Life Sci.
, vol.36
, pp. 2503-2508
-
-
Nicklas, W.J.1
Vyas, I.2
Heikkila, R.E.3
-
46
-
-
0036522967
-
Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease
-
Wu, D. C. et al. Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease.J. Neurosci. 22, 1763-1771 (2002).
-
(2002)
J. Neurosci.
, vol.22
, pp. 1763-1771
-
-
Wu, D.C.1
-
47
-
-
0344528794
-
The inflammatory reaction following 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine intoxication in mouse
-
doi:10.1006/exnr.1998.6993
-
Kurkowska-Jastrzebska, I., Wronska, A., Kohutnicka, M., Czlonkowski, A., & Czlonkowska, A. The inflammatory reaction following 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine intoxication in mouse. Exp. Neurol. 156, 50-61, doi:10.1006/exnr.1998.6993 (1999).
-
(1999)
Exp. Neurol.
, vol.156
, pp. 50-61
-
-
Kurkowska-Jastrzebska, I.1
Wronska, A.2
Kohutnicka, M.3
Czlonkowski, A.4
Czlonkowska, A.5
-
48
-
-
0030888286
-
In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining
-
Tatton, N. A., & Kish, S. J. In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining. Neuroscience. 77, 1037-1048 (1997).
-
(1997)
Neuroscience.
, vol.77
, pp. 1037-1048
-
-
Tatton, N.A.1
Kish, S.J.2
-
49
-
-
1442275733
-
Caspase-11 mediates inflammatory dopaminergic cell death in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
-
doi:10.1523/JNEUROSCI.3309-03.2004
-
Furuya, T. et al. Caspase-11 mediates inflammatory dopaminergic cell death in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. J Neurosci. 24, 1865-1872, doi:10.1523/JNEUROSCI.3309-03.2004 (2004).
-
(2004)
J Neurosci.
, vol.24
, pp. 1865-1872
-
-
Furuya, T.1
-
50
-
-
33845652290
-
Neuroprotection in Parkinson models varies with toxin administration protocol
-
doi:10.1111/j.1460-9568.2006.05192.x
-
Anderson, D. W., Bradbury, K. A., & Schneider, J. S. Neuroprotection in Parkinson models varies with toxin administration protocol. Eur. J. Neurosci. 24, 3174-3182, doi:10.1111/j.1460-9568.2006.05192.x (2006).
-
(2006)
Eur. J. Neurosci.
, vol.24
, pp. 3174-3182
-
-
Anderson, D.W.1
Bradbury, K.A.2
Schneider, J.S.3
|