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Volumn 61, Issue 12, 2007, Pages 991-1001

Behavioral and histopathological consequences of paraquat intoxication in mice: Effects of α-synuclein over-expression

Author keywords

Locus coeruleus; Mice; Parkinson's disease; Pesticide; Striatum; Substantia nigra

Indexed keywords

ALPHA SYNUCLEIN; BRAIN PROTEIN; PARAQUAT; TYROSINE 3 MONOOXYGENASE;

EID: 37249011444     PISSN: 08874476     EISSN: 10982396     Source Type: Journal    
DOI: 10.1002/syn.20456     Document Type: Article
Times cited : (161)

References (55)
  • 1
    • 7244236320 scopus 로고    scopus 로고
    • Inclusion body formation reduces levels of mutant Huntingtin and the risk of neuronal death
    • Arrasate M, Mitra S, Schweitzer ES, Segal MR, Finkbeiner S. 2004. Inclusion body formation reduces levels of mutant Huntingtin and the risk of neuronal death. Nature 431:805-810.
    • (2004) Nature , vol.431 , pp. 805-810
    • Arrasate, M.1    Mitra, S.2    Schweitzer, E.S.3    Segal, M.R.4    Finkbeiner, S.5
  • 2
    • 17644375851 scopus 로고    scopus 로고
    • Toxicity of redox cycling pesticides in primary mesencephalic cultures
    • Bonneh-Barkay D, Langston WJ, Di Monte DA. 2005. Toxicity of redox cycling pesticides in primary mesencephalic cultures. Antioxid Redox Signal 7:649-653.
    • (2005) Antioxid Redox Signal , vol.7 , pp. 649-653
    • Bonneh-Barkay, D.1    Langston, W.J.2    Di Monte, D.A.3
  • 3
    • 0032815531 scopus 로고    scopus 로고
    • Early effects of intrastriatal injections of quinolinic acid on microtubule-associated protein-2 and neuropeptides in rat basal ganglia
    • Bordelon YM, Chesselet MF. 1999. Early effects of intrastriatal injections of quinolinic acid on microtubule-associated protein-2 and neuropeptides in rat basal ganglia. Neuroscience 93:843-853.
    • (1999) Neuroscience , vol.93 , pp. 843-853
    • Bordelon, Y.M.1    Chesselet, M.F.2
  • 5
    • 33846419768 scopus 로고    scopus 로고
    • Stanley Fahn Lecture 2005: The staging procedure for the inclusion body pathology associated with sporadic Parkinson's disease reconsidered
    • Braak H, Bohl JR, Muller CM, Rub U, de Vos RA, Del Tredici K. 2006. Stanley Fahn Lecture 2005: The staging procedure for the inclusion body pathology associated with sporadic Parkinson's disease reconsidered. Mov Disord 21:2042-2051.
    • (2006) Mov Disord , vol.21 , pp. 2042-2051
    • Braak, H.1    Bohl, J.R.2    Muller, C.M.3    Rub, U.4    de Vos, R.A.5    Del Tredici, K.6
  • 6
    • 17844406856 scopus 로고    scopus 로고
    • α-Synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease
    • Chen L, Feany MB. 2005. α-Synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease. Nat Neurosci 8:657-663.
    • (2005) Nat Neurosci , vol.8 , pp. 657-663
    • Chen, L.1    Feany, M.B.2
  • 7
    • 33745140532 scopus 로고    scopus 로고
    • Proteasome dysfunction in aged human α-synuclein transgenic mice
    • Chen L, Thiruchelvam MJ, Madura K, Richfield EK. 2006. Proteasome dysfunction in aged human α-synuclein transgenic mice. Neurobiol Dis 23:120-126.
    • (2006) Neurobiol Dis , vol.23 , pp. 120-126
    • Chen, L.1    Thiruchelvam, M.J.2    Madura, K.3    Richfield, E.K.4
  • 8
    • 0035834360 scopus 로고    scopus 로고
    • Kinetic stabilization of the α-synuclein protofibril by a dopamine-α- synuclein adduct
    • Conway KA, Rochet JC, Bieganski RM, Lansbury PT Jr. 2001. Kinetic stabilization of the α-synuclein protofibril by a dopamine-α- synuclein adduct. Science 294:1346-1349.
    • (2001) Science , vol.294 , pp. 1346-1349
    • Conway, K.A.1    Rochet, J.C.2    Bieganski, R.M.3    Lansbury Jr., P.T.4
  • 11
    • 0025954066 scopus 로고
    • Ageing and Parkinson's disease: Substantia nigra regional selectivity
    • Fearnley JM, Lees AJ. 1991. Ageing and Parkinson's disease: Substantia nigra regional selectivity. Brain 114 (Part 5):2283-2301.
    • (1991) Brain , vol.114 , Issue.PART 5 , pp. 2283-2301
    • Fearnley, J.M.1    Lees, A.J.2
  • 12
    • 5144234034 scopus 로고    scopus 로고
    • α-Synuclein and transgenic mouse models
    • Fernagut PO, Chesselet MF. 2004. α-Synuclein and transgenic mouse models. Neurobiol Dis 17:123-130.
    • (2004) Neurobiol Dis , vol.17 , pp. 123-130
    • Fernagut, P.O.1    Chesselet, M.F.2
  • 17
    • 0023830780 scopus 로고
    • 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonian syndrome in Macaca fascicularis: Which midbrain dopaminergic neurons are lost?
    • German DC, Dubach M, Askari S, Speciale SG, Bowden DM. 1988. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonian syndrome in Macaca fascicularis: Which midbrain dopaminergic neurons are lost? Neuroscience 24:161-174.
    • (1988) Neuroscience , vol.24 , pp. 161-174
    • German, D.C.1    Dubach, M.2    Askari, S.3    Speciale, S.G.4    Bowden, D.M.5
  • 18
    • 0026712160 scopus 로고
    • Midbrain dopaminergic cell loss in Parkinson's disease and MPTP-induced Parkinsonism: Sparing of calbindin-D28k-containing cells
    • German DC, Manaye KF, Sonsalla PK, Brooks BA. 1992. Midbrain dopaminergic cell loss in Parkinson's disease and MPTP-induced Parkinsonism: Sparing of calbindin-D28k-containing cells. Ann N Y Acad Sci 648:42-62.
    • (1992) Ann N Y Acad Sci , vol.648 , pp. 42-62
    • German, D.C.1    Manaye, K.F.2    Sonsalla, P.K.3    Brooks, B.A.4
  • 19
    • 0025261771 scopus 로고
    • Patterns of cell and fiber vulnerability in the mesostriatal system of the mutant mouse weaver. I. Gradients and compartments
    • Graybiel AM, Ohta K, Roffler-Tarlov S. 1990. Patterns of cell and fiber vulnerability in the mesostriatal system of the mutant mouse weaver. I. Gradients and compartments. J Neurosci 10:720-733.
    • (1990) J Neurosci , vol.10 , pp. 720-733
    • Graybiel, A.M.1    Ohta, K.2    Roffler-Tarlov, S.3
  • 20
    • 2442636348 scopus 로고    scopus 로고
    • Biomedicine. Parkinson's - Divergent causes, convergent mechanisms
    • Greenamyre JT, Hastings TG. 2004. Biomedicine. Parkinson's - Divergent causes, convergent mechanisms. Science 304:1120-1122.
    • (2004) Science , vol.304 , pp. 1120-1122
    • Greenamyre, J.T.1    Hastings, T.G.2
  • 21
    • 11844262742 scopus 로고    scopus 로고
    • Gene expression profiling of rat midbrain dopamine neurons: Implications for selective vulnerability in Parkinsonism
    • Greene JG, Dingledine R, Greenamyre JT. 2005. Gene expression profiling of rat midbrain dopamine neurons: Implications for selective vulnerability in Parkinsonism. Neurobiol Dis 18:19-31.
    • (2005) Neurobiol Dis , vol.18 , pp. 19-31
    • Greene, J.G.1    Dingledine, R.2    Greenamyre, J.T.3
  • 22
    • 0018143270 scopus 로고
    • Antidromic identification of dopaminergic and other output neurons of the rat substantia nigra
    • Guyenet PG, Aghajanian GK. 1978. Antidromic identification of dopaminergic and other output neurons of the rat substantia nigra. Brain Res 150:69-84.
    • (1978) Brain Res , vol.150 , pp. 69-84
    • Guyenet, P.G.1    Aghajanian, G.K.2
  • 24
    • 33750349255 scopus 로고    scopus 로고
    • Critical appraisal of brain pathology staging related to presymptomatic and symptomatic cases of sporadic Parkinson's disease
    • Halliday GM, Del Tredici K, Braak H. 2006. Critical appraisal of brain pathology staging related to presymptomatic and symptomatic cases of sporadic Parkinson's disease. J Neural Transm Suppl:99-103.
    • (2006) J Neural Transm Suppl , pp. 99-103
    • Halliday, G.M.1    Del Tredici, K.2    Braak, H.3
  • 25
    • 0025230379 scopus 로고
    • Parkinson's disease: A case-control study of occupational and environmental risk factors
    • Hertzman C, Wiens M, Bowering D, Snow B, Calne D. 1990. Parkinson's disease: A case-control study of occupational and environmental risk factors. Am J Ind Med 17:349-355.
    • (1990) Am J Ind Med , vol.17 , pp. 349-355
    • Hertzman, C.1    Wiens, M.2    Bowering, D.3    Snow, B.4    Calne, D.5
  • 26
    • 5644284321 scopus 로고    scopus 로고
    • Polymorphisms of the α-synuclein promoter: Expression analyses and association studies in Parkinson's disease
    • Holzmann C, Kruger R, Saecker AM, Schmitt I, Schols L, Berger K, Riess O. 2003. Polymorphisms of the α-synuclein promoter: Expression analyses and association studies in Parkinson's disease. J Neural Transm 110:67-76.
    • (2003) J Neural Transm , vol.110 , pp. 67-76
    • Holzmann, C.1    Kruger, R.2    Saecker, A.M.3    Schmitt, I.4    Schols, L.5    Berger, K.6    Riess, O.7
  • 27
    • 14244261010 scopus 로고    scopus 로고
    • 3,4-Dihydroxyphenylalanine reverses the motor deficits in Pitx3-deficient aphakia mice: Behavioral characterization of a novel genetic model of Parkinson's disease
    • Hwang DY, Fleming SM, Ardayfio P, Moran-Gates T, Kim H, Tarazi FI, Chesselet MF, Kim KS. 2005. 3,4-Dihydroxyphenylalanine reverses the motor deficits in Pitx3-deficient aphakia mice: Behavioral characterization of a novel genetic model of Parkinson's disease. J Neurosci 25:2132-2137.
    • (2005) J Neurosci , vol.25 , pp. 2132-2137
    • Hwang, D.Y.1    Fleming, S.M.2    Ardayfio, P.3    Moran-Gates, T.4    Kim, H.5    Tarazi, F.I.6    Chesselet, M.F.7    Kim, K.S.8
  • 28
    • 0026348872 scopus 로고
    • Pathology of Parkinson's disease. Changes other than the nigrostriatal pathway
    • Jellinger KA. 1991. Pathology of Parkinson's disease. Changes other than the nigrostriatal pathway. Mol Chem Neuropathol 14:153-197.
    • (1991) Mol Chem Neuropathol , vol.14 , pp. 153-197
    • Jellinger, K.A.1
  • 29
    • 33749240943 scopus 로고    scopus 로고
    • Mechanisms of Parkinson's disease linked to pathological α-synuclein: New targets for drug discovery
    • Lee VM, Trojanowski JQ. 2006. Mechanisms of Parkinson's disease linked to pathological α-synuclein: New targets for drug discovery. Neuron 52:33-38.
    • (2006) Neuron , vol.52 , pp. 33-38
    • Lee, V.M.1    Trojanowski, J.Q.2
  • 30
    • 33746065340 scopus 로고    scopus 로고
    • Endogenous α-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity
    • Leng Y, Chuang DM. 2006. Endogenous α-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity. J Neurosci 26:7502-7512.
    • (2006) J Neurosci , vol.26 , pp. 7502-7512
    • Leng, Y.1    Chuang, D.M.2
  • 31
    • 0030513477 scopus 로고    scopus 로고
    • Midbrain dopaminergic neurons in the mouse that contain calbindin-D28k exhibit reduced vulnerability to MPTP-induced neurodegeneration
    • Liang CL, Sinton CM, Sonsalla PK, German DC. 1996. Midbrain dopaminergic neurons in the mouse that contain calbindin-D28k exhibit reduced vulnerability to MPTP-induced neurodegeneration. Neurodegeneration 5:313-318.
    • (1996) Neurodegeneration , vol.5 , pp. 313-318
    • Liang, C.L.1    Sinton, C.M.2    Sonsalla, P.K.3    German, D.C.4
  • 33
    • 0037127197 scopus 로고    scopus 로고
    • The herbicide paraquat causes up-regulation and aggregation of α-synuclein in mice: Paraquat and α-synuclein
    • Manning-Bog AB, McCormack AL, Li J, Uversky VN, Fink AL, Di Monte DA. 2002. The herbicide paraquat causes up-regulation and aggregation of α-synuclein in mice: Paraquat and α-synuclein. J Biol Chem 277:1641-1644.
    • (2002) J Biol Chem , vol.277 , pp. 1641-1644
    • Manning-Bog, A.B.1    McCormack, A.L.2    Li, J.3    Uversky, V.N.4    Fink, A.L.5    Di Monte, D.A.6
  • 35
    • 0343052652 scopus 로고    scopus 로고
    • Pole test is a useful method for evaluating the mouse movement disorder caused by striatal dopamine depletion
    • Matsuura K, Kabuto H, Makino H, Ogawa N. 1997. Pole test is a useful method for evaluating the mouse movement disorder caused by striatal dopamine depletion. J Neurosci Methods 73:45-48.
    • (1997) J Neurosci Methods , vol.73 , pp. 45-48
    • Matsuura, K.1    Kabuto, H.2    Makino, H.3    Ogawa, N.4
  • 38
    • 33745988224 scopus 로고    scopus 로고
    • Decreased susceptibility to oxidative stress underlies the resistance of specific dopaminergic cell populations to paraquat-induced degeneration
    • McCormack AL, Atienza JG, Langston JW, Di Monte DA. 2006. Decreased susceptibility to oxidative stress underlies the resistance of specific dopaminergic cell populations to paraquat-induced degeneration. Neuroscience 141:929-937.
    • (2006) Neuroscience , vol.141 , pp. 929-937
    • McCormack, A.L.1    Atienza, J.G.2    Langston, J.W.3    Di Monte, D.A.4
  • 41
    • 33846308531 scopus 로고    scopus 로고
    • Microglial activation as a priming event leading to paraquat-induced dopaminergic cell degeneration
    • Purisai MG, McCormack AL, Cumine S, Li J, Isla MZ, Di Monte DA. 2007. Microglial activation as a priming event leading to paraquat-induced dopaminergic cell degeneration. Neurobiol Dis 25:392-400.
    • (2007) Neurobiol Dis , vol.25 , pp. 392-400
    • Purisai, M.G.1    McCormack, A.L.2    Cumine, S.3    Li, J.4    Isla, M.Z.5    Di Monte, D.A.6
  • 42
    • 0036605566 scopus 로고    scopus 로고
    • Differential neuropathological alterations in transgenic mice expressing α-synuclein from the platelet-derived growth factor and Thy-1 promoters
    • Rockenstein E, Mallory M, Hashimoto M, Song D, Shults CW, Lang I, Masliah E. 2002. Differential neuropathological alterations in transgenic mice expressing α-synuclein from the platelet-derived growth factor and Thy-1 promoters. J Neurosci Res 68:568-578.
    • (2002) J Neurosci Res , vol.68 , pp. 568-578
    • Rockenstein, E.1    Mallory, M.2    Hashimoto, M.3    Song, D.4    Shults, C.W.5    Lang, I.6    Masliah, E.7
  • 43
    • 0030782462 scopus 로고    scopus 로고
    • Dopamine transporter mRNA levels are high in midbrain neurons vulnerable to MPTP
    • Sanghera MK, Manaye K, McMahon A, Sonsalla PK, German DC. 1997. Dopamine transporter mRNA levels are high in midbrain neurons vulnerable to MPTP. Neuroreport 8:3327-3331.
    • (1997) Neuroreport , vol.8 , pp. 3327-3331
    • Sanghera, M.K.1    Manaye, K.2    McMahon, A.3    Sonsalla, P.K.4    German, D.C.5
  • 44
    • 0032475931 scopus 로고    scopus 로고
    • Huntington acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions
    • Saudou F, Finkbeiner S, Devys D, Greenberg ME. 1998. Huntington acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions. Cell 95:55-66.
    • (1998) Cell , vol.95 , pp. 55-66
    • Saudou, F.1    Finkbeiner, S.2    Devys, D.3    Greenberg, M.E.4
  • 45
    • 0026711037 scopus 로고
    • Parkinson's disease and exposure to agricultural work and pesticide chemicals
    • Semchuk KM, Love EJ, Lee RG. 1992. Parkinson's disease and exposure to agricultural work and pesticide chemicals. Neurology 42:1328-1335.
    • (1992) Neurology , vol.42 , pp. 1328-1335
    • Semchuk, K.M.1    Love, E.J.2    Lee, R.G.3
  • 46
    • 0034531475 scopus 로고    scopus 로고
    • The α-synucleinopathies: Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy
    • Spillantini MG, Goedert M. 2000. The α-synucleinopathies: Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy. Ann N Y Acad Sci 920:16-27.
    • (2000) Ann N Y Acad Sci , vol.920 , pp. 16-27
    • Spillantini, M.G.1    Goedert, M.2
  • 48
    • 0035816404 scopus 로고    scopus 로고
    • Pesticides directly accelerate the rate of α-synuclein fibril formation: A possible factor in Parkinson's disease
    • Uversky VN, Li J, Fink AL. 2001. Pesticides directly accelerate the rate of α-synuclein fibril formation: A possible factor in Parkinson's disease. FEBS Lett 500:105-108.
    • (2001) FEBS Lett , vol.500 , pp. 105-108
    • Uversky, V.N.1    Li, J.2    Fink, A.L.3
  • 52
    • 0036457026 scopus 로고    scopus 로고
    • Design-based stereological methods for counting neurons
    • West MJ. 2002. Design-based stereological methods for counting neurons. Prog Brain Res 135:43-51.
    • (2002) Prog Brain Res , vol.135 , pp. 43-51
    • West, M.J.1
  • 53
    • 0026339976 scopus 로고
    • Unbiased stereological estimation of the total number of neurons in thesubdivisions of the rat hippocampus using the optical fractionator
    • West MJ, Slomianka L, Gundersen HJ. 1991. Unbiased stereological estimation of the total number of neurons in thesubdivisions of the rat hippocampus using the optical fractionator. Anat Rec 231:482-497.
    • (1991) Anat Rec , vol.231 , pp. 482-497
    • West, M.J.1    Slomianka, L.2    Gundersen, H.J.3
  • 54
    • 47049125102 scopus 로고    scopus 로고
    • Abnormal glutamate and dopamine receptor function in the striatum of α-synuclein overexpressing mice
    • Washington, DC, November 12-16
    • Wu N, Cepeda C, Masliah E, Levine MS. 2005.Abnormal glutamate and dopamine receptor function in the striatum of α-synuclein overexpressing mice. In: 35th Annual Meeting of the Society for Neuroscience, Washington, DC, November 12-16.
    • (2005) 35th Annual Meeting of the Society for Neuroscience
    • Wu, N.1    Cepeda, C.2    Masliah, E.3    Levine, M.S.4
  • 55
    • 0021235482 scopus 로고
    • Neurochemical compensation after nigrostriatal bundle injury in an animal model of preclinical Parkinsonism
    • Zigmond MJ, Acheson AL, Stachowiak MK, Strieker EM. 1984. Neurochemical compensation after nigrostriatal bundle injury in an animal model of preclinical Parkinsonism. Arch Neurol 41:856-861.
    • (1984) Arch Neurol , vol.41 , pp. 856-861
    • Zigmond, M.J.1    Acheson, A.L.2    Stachowiak, M.K.3    Strieker, E.M.4


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