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Volumn 73, Issue 1, 2013, Pages 129-135

Inhibition of 12/15-lipoxygenase as therapeutic strategy to treat stroke

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 15 LIPOXYGENASE; LIPOXYGENASE INHIBITOR; LOXBLOCK 1; UNCLASSIFIED DRUG;

EID: 84873411666     PISSN: 03645134     EISSN: 15318249     Source Type: Journal    
DOI: 10.1002/ana.23734     Document Type: Article
Times cited : (94)

References (33)
  • 1
    • 13944280025 scopus 로고    scopus 로고
    • Prioritizing interventions to improve rates of thrombolysis for ischemic stroke
    • California Acute Stroke Pilot Registry (CASPR) Investigators.
    • California Acute Stroke Pilot Registry (CASPR) Investigators. Prioritizing interventions to improve rates of thrombolysis for ischemic stroke. Neurology 2005; 64: 654-659.
    • (2005) Neurology , vol.64 , pp. 654-659
  • 2
    • 79751531393 scopus 로고    scopus 로고
    • Heart disease and stroke statistics - 2011 update: A report from the American Heart Association
    • Roger VL, Go AS, Lloyd-Jones DM, et al. Heart disease and stroke statistics-2011 update: a report from the American Heart Association. Circulation 2011; 123: e18-e209.
    • (2011) Circulation , vol.123
    • Roger, V.L.1    Go, A.S.2    Lloyd-Jones, D.M.3
  • 3
    • 77955487488 scopus 로고    scopus 로고
    • The science of stroke: Mechanisms in search of treatments
    • Moskowitz MA, Lo EH, Iadecola C,. The science of stroke: mechanisms in search of treatments. Neuron 2010; 67: 181-198.
    • (2010) Neuron , vol.67 , pp. 181-198
    • Moskowitz, M.A.1    Lo, E.H.2    Iadecola, C.3
  • 4
    • 64349101903 scopus 로고    scopus 로고
    • Oxidative stress and mitochondrial dysfunction as determinants of ischemic neuronal death and survival
    • Niizuma K, Endo H, Chan PH,. Oxidative stress and mitochondrial dysfunction as determinants of ischemic neuronal death and survival. J Neurochem 2009; 109 (suppl 1): 133-138.
    • (2009) J Neurochem , vol.109 , Issue.SUPPL. 1 , pp. 133-138
    • Niizuma, K.1    Endo, H.2    Chan, P.H.3
  • 5
    • 24644511604 scopus 로고    scopus 로고
    • Oxidative stress and neuronal death/survival signaling in cerebral ischemia
    • Saito A, Maier CM, Narasimhan P, et al. Oxidative stress and neuronal death/survival signaling in cerebral ischemia. Mol Neurobiol 2005; 31: 105-116.
    • (2005) Mol Neurobiol , vol.31 , pp. 105-116
    • Saito, A.1    Maier, C.M.2    Narasimhan, P.3
  • 6
    • 79952857040 scopus 로고    scopus 로고
    • Regulation of neuronal oxidative and nitrosative stress by endogenous protective pathways and disease processes
    • Hardingham GE, Lipton SA,. Regulation of neuronal oxidative and nitrosative stress by endogenous protective pathways and disease processes. Antioxid Redox Signal 2011; 14: 1421-1424.
    • (2011) Antioxid Redox Signal , vol.14 , pp. 1421-1424
    • Hardingham, G.E.1    Lipton, S.A.2
  • 7
    • 52449086378 scopus 로고    scopus 로고
    • Protecting against cerebrovascular injury: Contributions of 12/15-lipoxygenase to edema formation after transient focal ischemia
    • Jin G, Arai K, Murata Y, et al. Protecting against cerebrovascular injury: contributions of 12/15-lipoxygenase to edema formation after transient focal ischemia. Stroke 2008; 39: 2538-2543.
    • (2008) Stroke , vol.39 , pp. 2538-2543
    • Jin, G.1    Arai, K.2    Murata, Y.3
  • 8
    • 33845442015 scopus 로고    scopus 로고
    • Baicalein and 12/15-lipoxygenase in the ischemic brain
    • van Leyen K, Kim HY, Lee SR, et al. Baicalein and 12/15-lipoxygenase in the ischemic brain. Stroke 2006; 37: 3014-3018.
    • (2006) Stroke , vol.37 , pp. 3014-3018
    • Van Leyen, K.1    Kim, H.Y.2    Lee, S.R.3
  • 9
    • 26444609074 scopus 로고    scopus 로고
    • Neuroprotective properties of the natural vitamin e alpha-tocotrienol
    • Khanna S, Roy S, Slivka A, et al. Neuroprotective properties of the natural vitamin E alpha-tocotrienol. Stroke 2005; 36: 2258-2264.
    • (2005) Stroke , vol.36 , pp. 2258-2264
    • Khanna, S.1    Roy, S.2    Slivka, A.3
  • 10
    • 77956059859 scopus 로고    scopus 로고
    • Baicalein is neuroprotective in rat MCAO model: Role of 12/15-lipoxygenase, mitogen-activated protein kinase and cytosolic phospholipase A2
    • Cui L, Zhang X, Yang R, et al. Baicalein is neuroprotective in rat MCAO model: role of 12/15-lipoxygenase, mitogen-activated protein kinase and cytosolic phospholipase A2. Pharmacol Biochem Behav 2010; 96: 469-475.
    • (2010) Pharmacol Biochem Behav , vol.96 , pp. 469-475
    • Cui, L.1    Zhang, X.2    Yang, R.3
  • 11
    • 33748802214 scopus 로고    scopus 로고
    • Caffeic acid ameliorates early and delayed brain injuries after focal cerebral ischemia in rats
    • Zhou Y, Fang SH, Ye YL, et al. Caffeic acid ameliorates early and delayed brain injuries after focal cerebral ischemia in rats. Acta Pharmacol Sin 2006; 27: 1103-1110.
    • (2006) Acta Pharmacol Sin , vol.27 , pp. 1103-1110
    • Zhou, Y.1    Fang, S.H.2    Ye, Y.L.3
  • 12
    • 0026503717 scopus 로고
    • The lipoxygenase inhibitor phenidone protects against proteinuria and stroke in stroke-prone spontaneously hypertensive rats
    • Munsiff AV, Chander PN, Levine S, Stier CT Jr,. The lipoxygenase inhibitor phenidone protects against proteinuria and stroke in stroke-prone spontaneously hypertensive rats. Am J Hypertens 1992; 5: 56-63.
    • (1992) Am J Hypertens , vol.5 , pp. 56-63
    • Munsiff, A.V.1    Chander, P.N.2    Levine, S.3    Stier, Jr.C.T.4
  • 13
    • 0024414674 scopus 로고
    • Effect of MCI-186 on brain edema in rats
    • Nishi H, Watanabe T, Sakurai H, et al. Effect of MCI-186 on brain edema in rats. Stroke 1989; 20: 1236-1240.
    • (1989) Stroke , vol.20 , pp. 1236-1240
    • Nishi, H.1    Watanabe, T.2    Sakurai, H.3
  • 14
    • 0023947826 scopus 로고
    • Strong attenuation of ischemic and postischemic brain edema in rats by a novel free radical scavenger
    • Abe K, Yuki S, Kogure K,. Strong attenuation of ischemic and postischemic brain edema in rats by a novel free radical scavenger. Stroke 1988; 19: 480-485.
    • (1988) Stroke , vol.19 , pp. 480-485
    • Abe, K.1    Yuki, S.2    Kogure, K.3
  • 15
    • 36749068009 scopus 로고    scopus 로고
    • Baicalein, an antioxidant 12/15-lipoxygenase inhibitor improves clinical rating scores following multiple infarct embolic strokes
    • Lapchak PA, Maher P, Schubert D, Zivin JA,. Baicalein, an antioxidant 12/15-lipoxygenase inhibitor improves clinical rating scores following multiple infarct embolic strokes. Neuroscience 2007; 150: 585-591.
    • (2007) Neuroscience , vol.150 , pp. 585-591
    • Lapchak, P.A.1    Maher, P.2    Schubert, D.3    Zivin, J.A.4
  • 16
    • 40549137151 scopus 로고    scopus 로고
    • Novel lipoxygenase inhibitors as neuroprotective reagents
    • van Leyen K, Arai K, Jin G, et al. Novel lipoxygenase inhibitors as neuroprotective reagents. J Neurosci Res 2008; 86: 904-909.
    • (2008) J Neurosci Res , vol.86 , pp. 904-909
    • Van Leyen, K.1    Arai, K.2    Jin, G.3
  • 17
    • 79959532959 scopus 로고    scopus 로고
    • Development of neh2-luciferase reporter and its application for high throughput screening and real-time monitoring of nrf2 activators
    • Smirnova NA, Haskew-Layton RE, Basso M, et al. Development of neh2-luciferase reporter and its application for high throughput screening and real-time monitoring of nrf2 activators. Chem Biol 2011; 18: 752-765.
    • (2011) Chem Biol , vol.18 , pp. 752-765
    • Smirnova, N.A.1    Haskew-Layton, R.E.2    Basso, M.3
  • 18
    • 77950936168 scopus 로고    scopus 로고
    • Utilization of an in vivo reporter for high throughput identification of branched small molecule regulators of hypoxic adaptation
    • Smirnova NA, Rakhman I, Moroz N, et al. Utilization of an in vivo reporter for high throughput identification of branched small molecule regulators of hypoxic adaptation. Chem Biol 2010; 17: 380-391.
    • (2010) Chem Biol , vol.17 , pp. 380-391
    • Smirnova, N.A.1    Rakhman, I.2    Moroz, N.3
  • 19
    • 78049328458 scopus 로고    scopus 로고
    • The proteome of human brain after ischemic stroke
    • Cuadrado E, Rosell A, Colome N, et al. The proteome of human brain after ischemic stroke. J Neuropathol Exp Neurol 2010; 69: 1105-1115.
    • (2010) J Neuropathol Exp Neurol , vol.69 , pp. 1105-1115
    • Cuadrado, E.1    Rosell, A.2    Colome, N.3
  • 20
    • 77953139108 scopus 로고    scopus 로고
    • Increased nuclear apoptosis-inducing factor after transient focal ischemia: A 12/15-lipoxygenase-dependent organelle damage pathway
    • Pallast S, Arai K, Pekcec A, et al. Increased nuclear apoptosis-inducing factor after transient focal ischemia: a 12/15-lipoxygenase-dependent organelle damage pathway. J Cereb Blood Flow Metab 2010; 30: 1157-1167.
    • (2010) J Cereb Blood Flow Metab , vol.30 , pp. 1157-1167
    • Pallast, S.1    Arai, K.2    Pekcec, A.3
  • 21
    • 58149357106 scopus 로고    scopus 로고
    • Experimental model of warfarin-associated intracerebral hemorrhage
    • Foerch C, Arai K, Jin G, et al. Experimental model of warfarin-associated intracerebral hemorrhage. Stroke 2008; 39: 3397-3404.
    • (2008) Stroke , vol.39 , pp. 3397-3404
    • Foerch, C.1    Arai, K.2    Jin, G.3
  • 22
    • 46249131382 scopus 로고    scopus 로고
    • Effects of neuroglobin overexpression on acute brain injury and long-term outcomes after focal cerebral ischemia
    • Wang X, Liu J, Zhu H, et al. Effects of neuroglobin overexpression on acute brain injury and long-term outcomes after focal cerebral ischemia. Stroke 2008; 39: 1869-1874.
    • (2008) Stroke , vol.39 , pp. 1869-1874
    • Wang, X.1    Liu, J.2    Zhu, H.3
  • 23
    • 79957929098 scopus 로고    scopus 로고
    • Thrombotic distal middle cerebral artery occlusion produced by topical FeCl(3) application: A novel model suitable for intravital microscopy and thrombolysis studies
    • Karatas H, Erdener SE, Gursoy-Ozdemir Y, et al. Thrombotic distal middle cerebral artery occlusion produced by topical FeCl(3) application: a novel model suitable for intravital microscopy and thrombolysis studies. J Cereb Blood Flow Metab 2011; 31: 1452-1460.
    • (2011) J Cereb Blood Flow Metab , vol.31 , pp. 1452-1460
    • Karatas, H.1    Erdener, S.E.2    Gursoy-Ozdemir, Y.3
  • 24
    • 79451475649 scopus 로고    scopus 로고
    • A mouse model of hemorrhagic transformation by delayed tissue plasminogen activator administration after in situ thromboembolic stroke
    • Garcia-Yebenes I, Sobrado M, Zarruk JG, et al. A mouse model of hemorrhagic transformation by delayed tissue plasminogen activator administration after in situ thromboembolic stroke. Stroke 2011; 42: 196-203.
    • (2011) Stroke , vol.42 , pp. 196-203
    • Garcia-Yebenes, I.1    Sobrado, M.2    Zarruk, J.G.3
  • 25
    • 0025310826 scopus 로고
    • Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoprotein
    • Palinski W, Yla-Herttuala S, Rosenfeld ME, et al. Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoprotein. Arteriosclerosis 1990; 10: 325-335.
    • (1990) Arteriosclerosis , vol.10 , pp. 325-335
    • Palinski, W.1    Yla-Herttuala, S.2    Rosenfeld, M.E.3
  • 26
    • 80053904386 scopus 로고    scopus 로고
    • Complement factor H binds malondialdehyde epitopes and protects from oxidative stress
    • Weismann D, Hartvigsen K, Lauer N, et al. Complement factor H binds malondialdehyde epitopes and protects from oxidative stress. Nature 2011; 478: 76-81.
    • (2011) Nature , vol.478 , pp. 76-81
    • Weismann, D.1    Hartvigsen, K.2    Lauer, N.3
  • 27
    • 0030867994 scopus 로고    scopus 로고
    • A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion
    • Li Y, Maher P, Schubert D,. A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion. Neuron 1997; 19: 453-463.
    • (1997) Neuron , vol.19 , pp. 453-463
    • Li, Y.1    Maher, P.2    Schubert, D.3
  • 28
    • 0242290274 scopus 로고    scopus 로고
    • Molecular basis of vitamin e action: Tocotrienol modulates 12-lipoxygenase, a key mediator of glutamate-induced neurodegeneration
    • Khanna S, Roy S, Ryu H, et al. Molecular basis of vitamin E action: tocotrienol modulates 12-lipoxygenase, a key mediator of glutamate-induced neurodegeneration. J Biol Chem 2003; 278: 43508-43515.
    • (2003) J Biol Chem , vol.278 , pp. 43508-43515
    • Khanna, S.1    Roy, S.2    Ryu, H.3
  • 29
    • 4944264699 scopus 로고    scopus 로고
    • 12-Lipoxygenase plays a key role in cell death caused by glutathione depletion and arachidonic acid in rat oligodendrocytes
    • Wang H, Li J, Follett PL, et al. 12-Lipoxygenase plays a key role in cell death caused by glutathione depletion and arachidonic acid in rat oligodendrocytes. Eur J Neurosci 2004; 20: 2049-2058.
    • (2004) Eur J Neurosci , vol.20 , pp. 2049-2058
    • Wang, H.1    Li, J.2    Follett, P.L.3
  • 30
    • 9344268817 scopus 로고    scopus 로고
    • Peroxynitrite-induced neuronal apoptosis is mediated by intracellular zinc release and 12-lipoxygenase activation
    • Zhang Y, Wang H, Li J, et al. Peroxynitrite-induced neuronal apoptosis is mediated by intracellular zinc release and 12-lipoxygenase activation. J Neurosci 2004; 24: 10616-10627.
    • (2004) J Neurosci , vol.24 , pp. 10616-10627
    • Zhang, Y.1    Wang, H.2    Li, J.3
  • 31
    • 70349898267 scopus 로고    scopus 로고
    • 12/15-Lipoxygenase targets neuronal mitochondria under oxidative stress
    • Pallast S, Arai K, Wang X, et al. 12/15-Lipoxygenase targets neuronal mitochondria under oxidative stress. J Neurochem 2009; 111: 882-889.
    • (2009) J Neurochem , vol.111 , pp. 882-889
    • Pallast, S.1    Arai, K.2    Wang, X.3
  • 32
    • 79961207792 scopus 로고    scopus 로고
    • Oxidative damage in ischemic stroke revealed using multiple biomarkers
    • Seet RC, Lee CY, Chan BP, et al. Oxidative damage in ischemic stroke revealed using multiple biomarkers. Stroke 2011; 42: 2326-2329.
    • (2011) Stroke , vol.42 , pp. 2326-2329
    • Seet, R.C.1    Lee, C.Y.2    Chan, B.P.3
  • 33
    • 33144489526 scopus 로고    scopus 로고
    • Novel human lipoxygenase inhibitors discovered using virtual screening with homology models
    • Kenyon V, Chorny I, Carvajal WJ, et al. Novel human lipoxygenase inhibitors discovered using virtual screening with homology models. J Med Chem 2006; 49: 1356-1363.
    • (2006) J Med Chem , vol.49 , pp. 1356-1363
    • Kenyon, V.1    Chorny, I.2    Carvajal, W.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.