Trigonelline and diosgenin attenuate ER stress, oxidative stress-mediated damage in pancreas and enhance adipose tissue PPARγ activity in type 2 diabetic rats

Molecular and Cellular Biochemistry

Volumn 396, Issue 1-2, 2014, Pages 161-174

  Tharaheswari, M ^a   Jayachandra Reddy, N ^a   Kumar, R ^b   Varshney, K C ^b   Kannan, M ^a   Sudha Rani, S ^a  

^a PONDICHERRY UNIVERSITY   (India)

^b Rajiv Gandhi College of Yeterinary and Animal Sciences   (India)

Author keywords

Adipokines; Diosgenin; ER stress; PPARs; T2DM; Trigonelline

Indexed keywords

ALKALOID; DIOSGENIN; INSULIN; INTERLEUKIN 6; LEPTIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRIGONELLINE; TUMOR NECROSIS FACTOR ALPHA;

ADIPOSE TISSUE; ANIMAL; BLOOD; CHEMISTRY; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DRUG EFFECTS; ENDOPLASMIC RETICULUM STRESS; GENETICS; LIPID DIET; MALE; METABOLISM; MOLECULAR DOCKING; OXIDATIVE STRESS; PANCREAS; PATHOLOGY; SPRAGUE DAWLEY RAT;

ADIPOSE TISSUE; ALKALOIDS; ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DIET, HIGH-FAT; DIOSGENIN; ENDOPLASMIC RETICULUM STRESS; INSULIN; INTERLEUKIN-6; LEPTIN; MALE; MOLECULAR DOCKING SIMULATION; OXIDATIVE STRESS; PANCREAS; PPAR GAMMA; RATS, SPRAGUE-DAWLEY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84907594292     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-014-2152-x     Document Type: Article

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