Grape seed proanthocyanidins inhibit H2O2-induced osteoblastic MC3T3-E1 cell apoptosis via ameliorating H2O2-induced mitochondrial dysfunction

Journal of Toxicological Sciences

Volumn 39, Issue 5, 2014, Pages 803-813

  Zhang, Zhifeng ^a   Zheng, Leigang ^a   Zhao, Zhenqun ^a   Shi, Jun ^b   Wang, Xing ^b   Huang, Jian ^a  

^a The Second Affiliated Hospital of Inner Mongolia Medical University   (China)

^b Inner Mongolia Medical University   (China)

Author keywords

Apoptosis; MC3T3 E1 cells; Mitochondrial dysfunction; Proanthocyanidins

Indexed keywords

CASPASE 3; CYTOCHROME C OXIDASE; FREE RADICAL; GRAPE SEED EXTRACT; HYDROGEN PEROXIDE; MITOCHONDRIAL ENZYME; PROANTHOCYANIDIN; PROTEIN BCL 2; PROTEIN P53; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BONE MASS; CELL CULTURE; CELL LEVEL; CELL VIABILITY; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOLYSIS; OSTEOPOROSIS; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; DRUG EFFECTS; ETIOLOGY; METABOLISM; MITOCHONDRION; OXIDATIVE STRESS; PATHOLOGY;

ANIMALS; APOPTOSIS; BONE RESORPTION; CELLS, CULTURED; ELECTRON TRANSPORT COMPLEX IV; FREE RADICALS; GRAPE SEED EXTRACT; HYDROGEN PEROXIDE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MITOCHONDRIA; OSTEOBLASTS; OSTEOPOROSIS; OXIDATIVE STRESS; PROANTHOCYANIDINS;

EID: 84907562802     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.39.803     Document Type: Article

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