Grape seed proanthocyanidin extract (GSPE) attenuates collagen-induced arthritis

Immunology Letters

Volumn 124, Issue 2, 2009, Pages 102-110

  Cho, Mi La ^a   Heo, Yu Jung ^a   Park, Mi Kyung ^a   Oh, Hye Jwa ^a   Park, Jin Sil ^a   Woo, Yun Ju ^a   Ju, Ji Hyeon ^a   Park, Sung Hwan ^a   Kim, Ho Youn ^a   Min, Jun Ki ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

Antioxidant; Autoimmune arthritis; Collagen induced arthritis (CIA); Grape seed proanthocyanidin extract (GSPE); Oxidative stress

Indexed keywords

8 ISOPROSTANE; ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; CD4 ANTIGEN; COLONY STIMULATING FACTOR 1; GRAPE SEED EXTRACT; HYDROGEN PEROXIDE; IMMUNOGLOBULIN G2A; INTERLEUKIN 17; OSTEOCLAST DIFFERENTIATION FACTOR; PROANTHOCYANIDIN; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BONE EROSION; BONE MARROW CELL; CARTILAGE DEGENERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG DOSE COMPARISON; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; OSTEOCLAST; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SPLEEN CELL; SYNOVITIS;

ACID PHOSPHATASE; ANIMALS; ANKLE JOINT; ANTIBODIES; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; CELLS, CULTURED; COLLAGEN TYPE II; DISEASE MODELS, ANIMAL; HYDROGEN PEROXIDE; INTERLEUKIN-17; ISOENZYMES; ISOPROSTANES; MACROPHAGE COLONY-STIMULATING FACTOR; MICE; MICE, INBRED DBA; OSTEOCLASTS; PLANT EXTRACTS; PROANTHOCYANIDINS; RANK LIGAND; SPLEEN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 67349283330     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imlet.2009.05.001     Document Type: Article

References (58)

1. Filippin L.I., Vercelino R., Marroni N.P., and Xavier R.M. Redox signalling and the inflammatory response in rheumatoid arthritis. Clin Exp Immunol 152 (2008) 415-422
2. Dröge W. Free radicals in the physiological control of cell function. Physiol Rev 82 (2002) 47-95
3. Valko M., Leibfritz D., Moncol J., Cronin M.T., Mazur M., and Telser J. Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 39 (2007) 44-84
4. Bae S.C., Kim S.J., and Sung M.K. Inadequate antioxidant nutrient intake and altered plasma antioxidant status of rheumatoid arthritis patients. J Am Coll Nutr 22 (2003) 311-315
5. Comstock G.W., Burke A.E., Hoffman S.C., Helzlsouer K.J., Bendich A., Masi A.T., et al. Serum concentrations of alpha-tocopherol, beta-carotene, and retinol preceding the diagnosis of rheumatoid arthritis and systemic lupus erythematosus. Ann Rheum Dis 56 (1997) 323-325
6. Paredes S., Girona J., Hurt-Camejo E., Vallvé J.C., Olivé S., Heras M., et al. Antioxidant vitamins and lipid peroxidation in patients with rheumatoid arthritis: association with inflammatory markers. J Rheumatol 29 (2002) 2271-2277
7. van Vugt R.M., Rijken P.J., Rietveld A.G., van Vugt A.C., and Dijkmans B.A. Antioxidant intervention in rheumatoid arthritis: results of an open pilot study. Clin Rheumatol 27 (2008) 771-775
8. Ozkan Y., Yardým-Akaydýn S., Sepici A., Keskin E., Sepici V., and Simsek B. Oxidative status in rheumatoid arthritis. Clin Rheumatol 26 (2007) 64-68
9. Seven A., Güzel S., Aslan M., and Hamuryudan V. Lipid, protein, DNA oxidation and antioxidant status in rheumatoid arthritis. Clin Biochem 41 (2008) 538-543
10. Choi E.M. Oxidative status of DBA/1J mice with type II collagen-induced arthritis. J Appl Toxicol 27 (2007) 472-481
11. McCubbin M.D., Hou G., Abrams G.D., Dick R., Zhang Z., and Brewer G.J. Tetrathiomolybdate is effective in a mouse model of arthritis. J Rheumatol 33 (2006) 2501-2506
12. Bandt M.D., Grossin M., Driss F., Pincemail J., Babin-Chevaye C., and Pasquier C. Vitamin E uncouples joint destruction and clinical inflammation in a transgenic mouse model of rheumatoid arthritis. Arthritis Rheum 46 (2002) 522-532
13. Cuzzocrea S., McDonald M.C., Mota-Filipe H., Mazzon E., Costantino G., Britti D., et al. Beneficial effects of tempol, a membrane-permeable radical scavenger, in a rodent model of collagen-induced arthritis. Arthritis Rheum 43 (2000) 320-328
14. Lee E.Y., Lee C.K., Lee K.U., Park J.Y., Cho K.J., Cho Y.S., et al. Alpha-lipoic acid suppresses the development of collagen-induced arthritis and protects against bone destruction in mice. Rheumatol Int 27 (2007) 225-233
15. Kröger H., Miesel R., Dietrich A., Ohde M., Altrichter S., Braun C., et al. Suppression of type II collagen-induced arthritis by N-acetyl-l-cysteine in mice. Gen Pharmacol 29 (1997) 671-674
16. Haqqi T.M., Anthony D.D., Gupta S., Ahmad N., Lee M.S., Kumar G.K., et al. Prevention of collagen-induced arthritis in mice by a polyphenolic fraction from green tea. Proc Natl Acad Sci USA 96 (1999) 4524-4529
17. Morinobu A., Biao W., Tanaka S., Horiuchi M., Jun L., Tsuji G., et al. (-)-Epigalloc-atechin-3-gallate suppresses osteoclast differentiation and ameliorates experimental arthritis in mice. Arthritis Rheum 58 (2008) 2012-2018
18. Fine A.M. Oligomeric proanthocyanidin complexes: history, structure, and phytopharmaceutical applications. Altern Med Rev 5 (2000) 144-151
19. Ariga T. The antioxidative function, preventive action on disease and utilization of proanthocyanidins. Biofactors 21 (2004) 197-201
20. Bagchi D., Bagchi M., Stohs S.J., Das D.K., Ray S.D., Kuszynski C.A., et al. Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention. Toxicology 148 (2000) 187-197
21. Shi J., Yu J., Pohorly J.E., and Kakuda Y. Polyphenolics in grape seeds-biochemistry and functionality. J Med Food 6 (2003) 291-299
22. Sano A., Uchida R., Saito M., Shioya N., Komori Y., Tho Y., et al. Beneficial effects of grape seed extract on malondialdehyde-modified LDL. J Nutr Sci Vitaminol (Tokyo) 53 (2007) 174-182
23. Natella F., Belelli F., Gentili V., Ursini F., and Scaccini C. Grape seed proanthocyanidins prevent plasma postprandial oxidative stress in humans. J Agric Food Chem 50 (2002) 7720-7725
24. Yamakoshi J., Sano A., Tokutake S., Saito M., Kikuchi M., Kubota Y., et al. Oral intake of proanthocyanidin-rich extract from grape seeds improves chloasma. Phytother Res 18 (2004) 895-899
25. Stuart J.M., Cremer M.A., Kang A.H., and Townes A.S. Collagen-induced arthritis in rats. Evaluation of early immunologic events. Arthritis Rheum 22 (1979) 1344-1351
26. Park M.J., Min S.Y., Park K.S., Cho Y.G., Cho M.L., Jung Y.O., et al. Indoleamine 2,3-dioxygenase-expressing dendritic cells are involved in the generation of CD4+CD25+ regulatory T cells in Peyer's patches in an orally tolerized, collagen-induced arthritis mouse model. Arthritis Res Ther 10 (2008) R134
27. Rosloniec E.F., Cremer M., Kang A., and Myers L.K. Collagen-induced arthritis. In: Coligan J.E., Kruisbeek A.M., Margulies D.H., Shevach E.M., and Strober W. (Eds). Current protocols in immunology vol. 3 (1996), Wiley, New York 15.5.1-15.5.19
28. Camps M., Rückle T., Ji H., Ardissone V., Rintelen F., Shaw J., et al. Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis. Nat Med 11 (2005) 936-943
29. Pettit A.R., Ji H., von Stechow D., Müller R., Goldring S.R., Choi Y., et al. TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis. Am J Pathol 159 (2001) 1689-1699
30. Bendele A., McAbee T., Sennello G., Frazier J., Chlipala E., and McCabe D. Efficacy of sustained blood levels of interleukin-1 receptor antagonist in animal models of arthritis: comparison of efficacy in animal models with human clinical data. Arthritis Rheum 42 (1999) 498-506
31. Ju J.H., Cho M.L., Jhun J.Y., Park M.J., Oh H.J., Min S.Y., et al. Oral administration of type-II collagen suppresses IL-17-associated RANKL expression of CD4+ T cells in collagen-induced arthritis. Immunol Lett 117 (2008) 16-25
32. Ju J.H., Cho M.L., Moon Y.M., Oh H.J., Park J.S., Jhun J.Y., et al. IL-23 induces receptor activator of NF-kappaB ligand expression on CD4+ T cells and promotes osteoclastogenesis in an autoimmune arthritis model. J Immunol 181 (2008) 1507-1518
33. Brand D.D., Marion T.N., Myers L.K., Rosloniec E.F., Watson W.C., Stuart J.M., et al. Autoantibodies to murine type II collagen in collagen-induced arthritis: a comparison of susceptible and nonsusceptible strains. J Immunol 157 (1996) 5178-5184
34. Mageed R.A., Adams G., Woodrow D., Podhajcer O.L., and Chernajovsky Y. Prevention of collagen-induced arthritis by gene delivery of soluble p75 tumour necrosis factor receptor. Gene Ther 5 (1998) 1584-1592
35. Roark C.L., French J.D., Taylor M.A., Bendele A.M., Born W.K., and O'Brien R.L. Exacerbation of collagen-induced arthritis by oligoclonal, IL-17-producing gamma delta T cells. J Immunol 179 (2007) 5576-5583
36. Canter P.H., Wider B., and Ernst E. The antioxidant vitamins A, C, E and selenium in the treatment of arthritis: a systematic review of randomized clinical trials. Rheumatology (Oxford) 46 (2007) 1223-1233
37. Sehirli O., Ozel Y., Dulundu E., Topaloglu U., Ercan F., and Sener G. Grape seed extract treatment reduces hepatic ischemia-reperfusion injury in rats. Phytother Res 22 (2008) 43-48
38. Saavedra M.C., Dharajiya N.G., Redding D.R., Boldogh I., Lee C.Y., and Sur S. Scavenging of reactive oxidative species (ROS) generated by pollen NADPH oxidases inhibits Th2 and Th17 cytokine production from Johnson Grass (JG) sensitized human peripheral blood mononuclear cells (PBMCs). J Allergy Clin Immunol 119 Suppl. 1 (2007) 290
39. Elias K.M., Laurence A., Davidson T.S., Stephens G., Kanno Y., Shevach E.M., et al. Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway. Blood 111 (2008) 1013-1020
40. Nakae S., Nambu A., Sudo K., and Iwakura Y. Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice. J Immunol 171 (2003) 6173-6174
41. Shakhov A.N., Collart M.A., Vassalli P., Nedospasov S.A., and Jongeneel C.V. Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages. J Exp Med 171 (1990) 35-47
42. Shen F., Hu Z., Goswami J., and Gaffen S.L. Identification of common transcriptional regulatory elements in interleukin-17 target genes. J Biol Chem 281 (2006) 24138-24148
43. Karlsen A., Retterstøl L., Laake P., Paur I., Kjølsrud-Bøhn S., Sandvik L., et al. Anthocyanins inhibit nuclear factor-kappaB activation in monocytes and reduce plasma concentrations of pro-inflammatory mediators in healthy adults. J Nutr 137 (2007) 1951-1954
44. Schett G., Stolina M., Bolon B., Middleton S., Adlam M., Brown H., et al. Analysis of the kinetics of osteoclastogenesis in arthritic rats. Arthritis Rheum 52 (2005) 3192-3201
45. Lean J.M., Davies J.T., Fuller K., Jagger C.J., Kirstein B., Partington G.A., et al. A crucial role for thiol antioxidants in estrogen-deficiency bone loss. J Clin Invest 112 (2003) 915-923
46. Koh J.M., Lee Y.S., Byun C.H., Chang E.J., Kim H., Kim Y.H., et al. Alpha-lipoic acid suppresses osteoclastogenesis despite increasing the receptor activator of nuclear factor kappaB ligand/osteoprotegerin ratio in human bone marrow stromal cells. J Endocrinol 185 (2005) 401-413
47. Rabovsky A., Cuomo J., and Eich N. Measurement of plasma antioxidant reserve after supplementation with various antioxidants in healthy subjects. Clin Chim Acta 371 (2006) 55-60
48. Basu S., and Helmersson J. Factors regulating isoprostane formation in vivo. Antioxid Redox Signal 7 (2005) 221-235
49. Wuyts W.A., Vanaudenaerde B.M., Dupont L.J., Van Raemdonck D.E., Demedts M.G., and Verleden G.M. N-acetylcysteine inhibits interleukin-17-induced interleukin-8 production from human airway smooth muscle cells: a possible role for anti-oxidative treatment in chronic lung rejection?. J Heart Lung Transplant 23 (2004) 122-127
50. Shang F.J., Zhao L.Y., Zheng Q.S., Wang J.P., Xu Z., Liang W.B., et al. Simvastatin inhibits lipopolysaccharide-induced tumor necrosis factor-a expression in neonatal rat cardiomyocytes: the role of reactive oxygen species. Biochem Biophys Res Commun 351 (2006) 947-952
51. Miyoshi N., Oubrahim H., Chock P.B., and Stadtman E.R. Age-dependent cell death and the role of ATP in hydrogen peroxide-induced apoptosis and necrosis. Proc Natl Acad Sci USA 103 (2006) 1727-1731
52. Bagchi D., Kuszynski C.A., Balmoori J., Bagchi M., and Stohs S.J. Hydrogen peroxide-induced modulation of intracellular oxidized states in cultured macrophage J774A.1 and neuroactive PC-12 cells, and protection by a novel IH636 grape seed proanthocyanidin extract. Phytother Res 12 (1998) 568-571
53. Bax B.E., Alam A.S., Banerji B., Bax C.M., Bevis P.J., Stevens C.R., et al. Stimulation of osteoclastic bone resorption by hydrogen peroxide. Biochem Biophys Res Commun 183 (1992) 1153-1158
54. Li W.G., Zhang X.Y., Wu Y.J., and Tian X. Anti-inflammatory effect and mechanism of proanthocyanidins from grape seeds. Acta Pharmacol Sin 22 (2001) 1117-1120
55. Hultqvist M., Bäcklund J., Bauer K., Gelderman K.A., and Holmdahl R. Lack of reactive oxygen species breaks T cell tolerance to collagen type II and allows development of arthritis in mice. J Immunol 179 (2007) 1431-1437
56. Gelderman K.A., Hultqvist M., Pizzolla A., Zhao M., Nandakumar K.S., Mattsson R., et al. Macrophages suppress T cell responses and arthritis development in mice by producing reactive oxygen species. J Clin Invest 117 (2007) 3020-3028
57. Lee K.W., and Lee H.J. Biphasic effects of dietary antioxidants on oxidative stress-mediated carcinogenesis. Mech Ageing Dev 127 (2006) 424-431
58. Gelderman K.A., Hultqvist M., Olsson L.M., Bauer K., Pizzolla A., Olofsson P., et al. Rheumatoid arthritis: the role of reactive oxygen species in disease development and therapeutic strategies. Antioxid Redox Signal 9 (2007) 1541-1567