Heme oxygenase-1 deficiency accompanies neuropathogenesis of HIV-associated neurocognitive disorders

Journal of Clinical Investigation

Volumn 124, Issue 10, 2014, Pages 4459-4472

  Gill, Alexander J ^a   Kovacsics, Colleen E ^a   Cross, Stephanie A ^a   Vance, Patricia J ^a   Kolson, Lorraine L ^a   Jordan Sciutto, Kelly L ^b   Gelman, Benjamin B ^c   Kolson, Dennis L ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA SCHOOL OF DENTAL MEDICINE   (United States)

^c UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUMARIC ACID DIMETHYL ESTER; GAMMA INTERFERON; GLUTAMIC ACID; HEME OXYGENASE 1; HOST FACTOR; SMALL INTERFERING RNA; ANTIOXIDANT; FUMARIC ACID DERIVATIVE; HMOX1 PROTEIN, HUMAN;

ARTICLE; ASTROCYTE; COGNITIVE DEFECT; DISEASE CARRIER; ENZYME DEFICIENCY; ENZYME INHIBITION; HEME OXYGENASE 1 DEFICIENCY; HIV ASSOCIATED DEMENTIA; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IN VITRO STUDY; MACROPHAGE; MACROPHAGE ACTIVATION; MICROGLIA; NERVE DEGENERATION; NEUROPATHOLOGY; NEUROTOXICITY; PROTEIN EXPRESSION; SUPERNATANT; VIRUS REPLICATION; ADULT; AGED; BRAIN; CENTRAL NERVOUS SYSTEM; CHEMISTRY; COHORT ANALYSIS; COMPLICATION; DEFICIENCY; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; INFLAMMATION; MALE; METABOLISM; MIDDLE AGED; NEUROLOGIC DISEASE; OXIDATIVE STRESS; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PREFRONTAL CORTEX; STATISTICAL MODEL; VIROLOGY;

ADULT; AGED; ANTIOXIDANTS; ASTROCYTES; BRAIN; CENTRAL NERVOUS SYSTEM; COGNITION DISORDERS; COHORT STUDIES; DIMETHYL FUMARATE; FEMALE; FUMARATES; HEME OXYGENASE-1; HIV INFECTIONS; HIV-1; HUMANS; INFLAMMATION; LINEAR MODELS; MACROPHAGES; MALE; MICROGLIA; MIDDLE AGED; NERVOUS SYSTEM DISEASES; OXIDATIVE STRESS; PREFRONTAL CORTEX; RNA, SMALL INTERFERING; VIRUS REPLICATION;

EID: 84907486040     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI72279     Document Type: Article

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