CD163 identifies a unique population of ramified microglia in HIV encephalitis (HIVE)

Journal of Neuropathology and Experimental Neurology

Volumn 63, Issue 12, 2004, Pages 1255-1264

  Roberts, Eleanor S ^a   Masliah, Eleizer ^b   Fox, Howard S ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Alzheimer disease; CD163; HIVE; Microglia; SIVE; Variant Creutzfeldt Jakob disease (vCJD)

Indexed keywords

ANTIGEN; CD163 ANTIGEN; GLUCOSE TRANSPORTER 5; HLA DR ANTIGEN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANTIGEN EXPRESSION; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CREUTZFELDT JAKOB DISEASE; DEMENTIA; DISEASE SEVERITY; ENCEPHALITIS; GRAY MATTER; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; IMMUNOREACTIVITY; MACROPHAGE; MICROGLIA; MONOCYTE; NERVE INJURY; PHAGOCYTOSIS; PRIORITY JOURNAL; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 10044292902     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnen/63.12.1255     Document Type: Article

References (51)

1. Kreutzberg GW. Microglia, the first line of defence in brain pathologies. Arzneimittelforschung 1995;45:357-60
2. Davis EJ, Foster TD, Thomas WE. Cellular forms and functions of brain microglia. Brain Res Bull 1994;34:73-78
3. Boven LA, Middel J, Breij EC, et al. Interactions between HIV-infected monocyte-derived macrophages and human brain microvascular endothelial cells result in increased expression of CC chemokines. J Neurovirol 2000;6:382-89
4. Streit WJ, Walter SA, Pennell NA. Reactive microgliosis. Prog Neurobiol 1999;57:563-81
5. Gehrmann J, Matsumoto Y, Kreutzberg GW. Microglia: Intrinsic immuneffector cell of the brain. Brain Res Brain Res Rev 1995;20:269-87
6. Streit WJ, Sparks DL. Activation of microglia in the brains of humans with heart disease and hypercholesterolemic rabbits. J Mol Med 1997;75:130-38
7. Wilson MA, Molliver ME. Microglial response to degeneration of serotonergic axon terminals. Glia 1994;11:18-34
8. Feigin I, Naoumenko J. Some chemical principles applicable to some silver and gold staining methods for neuropathological studies. J Neuropathol Exp Neurol 1976;35:495-507
9. Roberts ES, Zandonatti MA, Watry DD, et al. Induction of pathogenic sets of genes in macrophages and neurons in NeuroAIDS. Am J Pathol 2003;162:2041-57
10. Horikoshi Y, Sasaki A, Taguchi N, et al. Human GLUT5 immunolabeling is useful for evaluating microglial status in neuropathological study using paraffin sections. Acta Neuropathol (Berl) 2003;105:157-62
11. Law SK, Micklem KJ, Shaw JM, et al. A new macrophage differentiation antigen which is a member of the scavenger receptor superfamily. Eur J Immunol 1993;23:2320-25
12. Hogger P, Dreier J, Droste A, Buck F, Sorg C. Identification of the integral membrane protein RM3/1 on human monocytes as a glucocorticoid-inducible member of the scavenger receptor cysteine-rich family (CD163). J Immunol 1998;161:1883-90
13. Zwadlo G, Voegeli R, Osthoff KS, Sorg C. A monoclonal antibody to a novel differentiation antigen on human macrophages associated with the down-regulatory phase of the inflammatory process. Exp Cell Biol 1987;55:295-304
14. Sulahian TH, Hogger P, Wahner AE, et al. Human monocytes express CD163, which is upregulated by IL-10 and identical to p155. Cytokine 2000;12:I312-21
15. Ritter M, Buechler C, Langmann T, Schmitz G. Genomic organization and chromosomal localization of the human CD163 (M130) gene: A member of the scavenger receptor cysteine-rich superfamily. Biochem Biophys Res Commun 1999;260:466-74
16. Wenzel I, Roth J, Sorg C. Identification of a novel surface molecule, RM3/1, that contributes to the adhesion of glucocorticoid-induced human monocytes to endothelial cells. Eur J Immunol 1996;26:2758-63
17. Djemadji-Oudjiel N, Goerdt S, Kodelja V, Schmuth M, Orfanos CE. Immunohistochemical identification of type II alternatively activated dendritic macrophages (RM 3/1+3, MS-1 ±, 25F9-) in psoriatic dermis. Arch Dermatol Res 1996;288:757-64
18. Okamoto H, Nakano K. Regulation of interleukin-1 synthesis by histamine produced by mouse peritoneal macrophages per se. Immunology 1990;69:162-65
19. Hotermans G, Bury T, Radermecker MF. Effect of histamine on tumor necrosis factor production by human monocytes. Int Arch Allergy Appl Immunol 1991;95:278-81
20. Ritter M, Buechler C, Kapinsky M, Schmilz G. Interaction of CD163 with the regulatory subunit of casein kinase II (CKII) and dependence of CD163 signaling on CKII and protein kinase C. Eur J Immunol 2001;31:999-1009
21. Hamann W, Floter A, Schmutzler W, Zwadlo-Klarwasser G. Characterization of a novel anti-inflammatory factor produced by RM3/1 macrophages derived from glucocorticoid treated human monocytes. Inflamm Res 1995;44:535-40
22. Philippidis P, Mason JC, Evans BJ, et al. Hemoglobin scavenger receptor CD163 mediates interleukin-10 release and heme oxygenase-1 synthesis: Antiinflammatory monocyte-macrophage responses in vitro, in resolving skin blisters in vivo, and after cardiopulmonary bypass surgery. Circ Res 2004;94:119-26
23. Van den Heuvel MM, Tensen CP, van As JH, et al. Regulation of CD 163 on human macrophages: Cross-linking of CD163 induces signaling and activation. J Leukoc Biol 1999;66:858-66
24. Hauptmann S, Bernauer J, Zwadlo-Klarwasser G, Klosterhalfen B, Kirkpatrick CJ. Differential adherence of the human monocyte subsets 27E10 and RM3/1 to cytokine- or glucocorticoid-treated endothelial cells. Pathobiology 1994;62:262-68
25. Rezaie P, Lantos PL. Microglia and the pathogenesis of spongiform encephalopathies. Brain Res Brain Res Rev 2001;35:55-72
26. Sasaki A, Hirato J, Nakazato Y. Immunohistochemical study of microglia in the Creutzfeldt-Jakob diseased brain. Acta Neuropathol (Berl) 1993;86:337-44
27. Eikelenboom P, Veerhuis R. The role of complement and activated microglia in the pathogenesis of Alzheimer's disease. Neurobiol Aging 1996;17:673-80
28. Cagnin A, Brooks DJ, Kennedy AM, et al. In-vivo measurement of activated microglia in dementia. Lancet 2001;358:461-67
29. Eikelenboom P, Bate C, Van Gool WA, et al. Neuroinflammation in Alzheimer's disease and prion disease. Glia 2002;40:232-39
30. Services UDoHaH, Prevention CfDCa, Health NIo. Biosafety in microbiological and biomedical laboratories. Washington DC: US Government Printing Office, May 1999
31. Perry VH, Gordon S. Macrophages and microglia in the nervous system. Trends Neurosci 1988;11:273-77
32. Everall IP, Heaton RK, Marcotte TD, et al. Cortical synaptic density is reduced in mild to moderate human immunodeficiency virus neurocognitive disorder. HNRC Group. HIV Neurobehavioral Research Center. Brain Pathol 1999;9:209-17
33. Masliah E, Heaton RK, Marcotte TD, et al. Dendritic injury is a pathological substrate for human immunodeficiency virus-related cognitive disorders. HNRC Group. The HIV Neurobehavioral Research Center. Ann Neurol 1997;42:963-72
34. Glass JD, Fedor H, Wesselingh SL, McArthur JC. Immunocytochemical quantitation of human immunodeficiency virus in the brain: Correlations with dementia. Ann Neurol 1995;38:755-62
35. Blinzinger K, Kreutzberg G. Displacement of synaptic terminals from regenerating motoneurons by microglial cells. Z Zellforsch Mikrosk Anat 1968;85:145-57
36. Gehrmann J, Schoen SW, Kreutzberg GW. Lesion of the rat entorhinal cortex leads to a rapid microglial reaction in the dentate gyrus. A light and electron microscopical study. Acta Neuropathol (Berl) 1991;82:442-55
37. Colasanti M, Persichini T, Di Pucchio T, Gremo F, Lauro GM. Human ramified microglial cells produce nitric oxide upon Escherichia coli lipopolysaccharide and tumor necrosis factor alpha stimulation. Neurosci Lett 1995;200:144-46
38. Gendelman HE, Lipton SA, Tardieu M, Bukrinsky MI, Nottet HS. The neuropathogenesis of HIV-1 infection. J Leukoc Biol 1994;56:389-98
39. Morgan MJ, Kimes AS, London ED. Possible roles for nitric oxide in AIDS and associated pathology. Med Hypotheses 1992;38:189-93
40. Boche D, Khatissian E, Gray F, Falanga P, Montagnier L, Hurtrel B. Viral load and neuropathology in the SIV model. J Neurovirol 1999;5:232-40
41. Zwadlo-Klarwasser G, Bent S, Haubeck HD, Sorg C, Schmutzler W. Glucocorticoid-induced appearance of the macrophage subtype RM 3/1 in peripheral blood of man. Int Arch Allergy Appl Immunol 1990;91:175-80
42. Goerdt S, Politz O, Schledzewski K, et al. Alternative versus classical activation of macrophages. Pathobiology 1999;67:222-26
43. Kodelja V, Muller C, Tenorio S, Schebesch C, Orfanos CE, Goerdt S. Differences in angiogenic potential of classically vs alternatively activated macrophages. Immunobiology 1997;197:478-93
44. Topoll HH, Zwadlo G, Lange DE, Sorg C. Phenotypic dynamics of macrophage subpopulations during human experimental gingivitis. J Periodontal Res 1989;24:106-12
45. Hogger P, Sorg C. Soluble CD163 inhibits phorbol ester-induced lymphocyte proliferation. Biochem Biophys Res Commun 2001;288:841-43
46. Chang MD, Pollard JW, Khalili H, Goyert SM, Diamond B. Mouse placental macrophages have a decreased ability to present antigen. Proc Natl Acad Sci U S A 1993;90:462-66
47. Mues B, Langer D, Zwadlo G, Sorg C. Phenotypic characterization of macrophages in human term placenta. Immunology 1989;67:303-7
48. Baker CA, Martin D, Manuelidis L. Microglia from Creutzfeldt-Jakob disease-infected brains are infectious and show specific mRNA activation profiles. J Virol 2002;76:10905-13
49. Peyrin JM, Lasmezas CI, Haik S, et al. Microglial cells respond to amyloidogenic PrP peptide by the production of inflammatory cytokines. Neuroreport 1999;10:723-29
50. Carpenter AF, Carpenter PW, Markesbery WR. Morphometric analysis of microglia in Alzheimer's disease. J Neuropathol Exp Neurol 1993;52:601-8
51. Gebicke-Haerter PJ, Van Calker D, Norenberg W, Illes P. Molecular mechanisms of microglial activation. A. Implications for regeneration and neurodegenerative diseases. Neurochem Int 1996;29:1-12