Dimethyl fumarate, an immune modulator and inducer of the antioxidant response, suppresses HIV replication and macrophage-mediated neurotoxicity: A novel candidate for HIV neuroprotection

Journal of Immunology

Volumn 187, Issue 10, 2011, Pages 5015-5025

  Cross, Stephanie A ^a   Cook, Denise R ^a   Chi, Anthony W S ^a   Vance, Patricia J ^a   Kolson, Lorraine L ^a   Wong, Bethany J ^a   Jordan Sciutto, Kelly L ^b   Kolson, Dennis L ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EFAVIRENZ; FUMARIC ACID DERIVATIVE; FUMARIC ACID DIMETHYL ESTER; FUMARIC ACID METHYL ESTER; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUROTOXIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CELL NUCLEUS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EMBRYO; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOMODULATION; IN VITRO STUDY; MACROPHAGE; MONOCYTE DERIVED MACROPHAGE; NEUROPROTECTION; NEUROTOXICITY; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; RAT; VIRUS INHIBITION; VIRUS REPLICATION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANTI-HIV AGENTS; ANTIOXIDANTS; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; FUMARATES; HIV-1; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MACROPHAGES; MONOCYTES; NEURONS; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; VIRUS REPLICATION;

EID: 81455135889     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1101868     Document Type: Article

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