Human immunodeficiency virus (HIV)-induced neurotoxicity: Roles for the NMDA receptor subtypes 2A and 2B and the calcium-activated protease calpain by a CSF-derived HIV-1 strain

Journal of Neuroscience

Volumn 26, Issue 3, 2006, Pages 981-990

  O'Donnell, Lauren A ^a   Agrawal, Arpita ^a   Jordan Sciutto, Kelly L ^a   Dichter, Marc A ^a   Lynch, David R ^a   Kolson, Dennis L ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Calpain; Hippocampus; HIV 1; Macrophage; Neurotoxicity; NMDA receptor; Virus

Indexed keywords

CALCIUM; CALPAIN; EXCITOTOXIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; NEUROTOXIN; RECEPTOR BLOCKING AGENT;

ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; BRAIN INFECTION; BRAIN REGION; CELL CULTURE; CELL DIVISION; CEREBROSPINAL FLUID; CONTROLLED STUDY; DEMENTIA; DISEASE PREDISPOSITION; HIPPOCAMPUS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; MACROPHAGE; NERVE CELL NECROSIS; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; VIRUS INFECTION; VIRUS STRAIN;

ANIMALS; ANTI-HIV AGENTS; CALPAIN; CELLS, CULTURED; CYSTEINE PROTEINASE INHIBITORS; EXCITATORY AMINO ACID ANTAGONISTS; HIPPOCAMPUS; HIV-1; HUMANS; MACROPHAGES; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 32544441212     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4617-05.2006     Document Type: Article

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