Gene transfection of H25A mutant heme oxygenase-1 protects cells against hydroperoxide-induced cytotoxicity

Journal of Biological Chemistry

Volumn 277, Issue 12, 2002, Pages 10712-10718

  Hori, Rio ^a   Kashiba, Misato ^b   Toma, Tomoko ^c   Yachie, Akihiro ^c   Goda, Nobuhito ^a   Makino, Nobuya ^b   Soejima, Akinori ^c   Nagasawa, Toshihiko ^c   Nakabayashi, Kimimasa ^a   Suematsu, Makoto ^a  

^a KEIO UNIVERSITY   (Japan)

^b KYORIN UNIVERSITY   (Japan)

^c KANAZAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; CELLS; ENZYMES; GENES; OXIDATION;

GENE TRANSFECTION;

BIOCHEMISTRY;

BILIRUBIN; CATALASE; GLUTATHIONE; HEME OXYGENASE 1; HYDROGEN PEROXIDE; IRON; MUTANT PROTEIN; OXIDIZING AGENT; TERT BUTYL HYDROPEROXIDE;

ANIMAL CELL; ARTICLE; CATALYSIS; CELL PROTECTION; CELL STRAIN U937; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME ACTIVITY; GENETIC TRANSFECTION; GLUTATHIONE METABOLISM; HUMAN; HUMAN CELL; MUTANT; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; CATALASE; CELL DEATH; CELLS, CULTURED; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE; HEME OXYGENASE (DECYCLIZING); HEME OXYGENASE-1; HEMIN; HUMANS; HYDROGEN PEROXIDE; IRON; MEMBRANE PROTEINS; MUTATION; OXIDANTS; OXIDATIVE STRESS; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; TIME FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED; U937 CELLS; UP-REGULATION;

ANIMALIA;

EID: 0037155806     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M107749200     Document Type: Article

References (27)