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Volumn 193, Issue 8, 2014, Pages 4203-4213

TLR2-dependent activation of β-catenin pathway in dendritic cells induces regulatory responses and attenuates autoimmune inflammation

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CYTOKINE; INTERLEUKIN 10; PROTEIN KINASE B; RETINAL DEHYDROGENASE; RETINALDEHYDE DEHYDROGENASE 2; T CELL FACTOR 4 PROTEIN; T CELL FACTOR PROTEIN; TOLL LIKE RECEPTOR 2; UNCLASSIFIED DRUG; ZYMOSAN; AKT1 PROTEIN, MOUSE; ALDEHYDE DEHYDROGENASE; ALDH1A2 PROTEIN, MOUSE; DECTIN 1; IL10 PROTEIN, MOUSE; LECTIN; TCF7L2 PROTEIN, MOUSE; TLR2 PROTEIN, MOUSE; TRANSCRIPTION FACTOR 7 LIKE 2;

EID: 84907481833     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1400614     Document Type: Article
Times cited : (65)

References (68)
  • 1
    • 0036518287 scopus 로고    scopus 로고
    • Mouse and human dendritic cell subtypes
    • Shortman, K., and Y. J. Liu. 2002. Mouse and human dendritic cell subtypes. Nat. Rev. Immunol. 2: 151-161.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 151-161
    • Shortman, K.1    Liu, Y.J.2
  • 2
    • 2942516628 scopus 로고    scopus 로고
    • Modulating vaccine responses with dendritic cells and Tolllike receptors
    • Pulendran, B. 2004. Modulating vaccine responses with dendritic cells and Tolllike receptors. Immunol. Rev. 199: 227-250.
    • (2004) Immunol. Rev. , vol.199 , pp. 227-250
    • Pulendran, B.1
  • 3
    • 34250159927 scopus 로고    scopus 로고
    • Development of dendritic-cell lineages
    • Wu, L., and Y. J. Liu. 2007. Development of dendritic-cell lineages. Immunity 26: 741-750.
    • (2007) Immunity , vol.26 , pp. 741-750
    • Wu, L.1    Liu, Y.J.2
  • 4
    • 35748978808 scopus 로고    scopus 로고
    • Taming cancer by inducing immunity via dendritic cells
    • Palucka, A. K., H. Ueno, J. W. Fay, and J. Banchereau. 2007. Taming cancer by inducing immunity via dendritic cells. Immunol. Rev. 220: 129-150.
    • (2007) Immunol. Rev. , vol.220 , pp. 129-150
    • Palucka, A.K.1    Ueno, H.2    Fay, J.W.3    Banchereau, J.4
  • 5
    • 34848837386 scopus 로고    scopus 로고
    • Taking dendritic cells into medicine
    • Steinman, R. M., and J. Banchereau. 2007. Taking dendritic cells into medicine. Nature 449: 419-426.
    • (2007) Nature , vol.449 , pp. 419-426
    • Steinman, R.M.1    Banchereau, J.2
  • 7
    • 79954506102 scopus 로고    scopus 로고
    • Dendritic cell control of tolerogenic responses
    • Manicassamy, S., and B. Pulendran. 2011. Dendritic cell control of tolerogenic responses. Immunol. Rev. 241: 206-227.
    • (2011) Immunol. Rev. , vol.241 , pp. 206-227
    • Manicassamy, S.1    Pulendran, B.2
  • 8
    • 0742324857 scopus 로고    scopus 로고
    • Toll-like receptors and acquired immunity
    • Pasare, C., and R. Medzhitov. 2004. Toll-like receptors and acquired immunity. Semin. Immunol. 16: 23-26.
    • (2004) Semin. Immunol. , vol.16 , pp. 23-26
    • Pasare, C.1    Medzhitov, R.2
  • 10
    • 0141688292 scopus 로고    scopus 로고
    • DC-SIGN: Escape mechanism for pathogens
    • van Kooyk, Y., and T. B. Geijtenbeek. 2003. DC-SIGN: escape mechanism for pathogens. Nat. Rev. Immunol. 3: 697-709.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 697-709
    • Van Kooyk, Y.1    Geijtenbeek, T.B.2
  • 11
    • 0035817818 scopus 로고    scopus 로고
    • Immune recognition: A new receptor for β-glucans
    • Brown, G. D., and S. Gordon. 2001. Immune recognition: a new receptor for β-glucans. Nature 413: 36-37.
    • (2001) Nature , vol.413 , pp. 36-37
    • Brown, G.D.1    Gordon, S.2
  • 14
    • 0038558249 scopus 로고    scopus 로고
    • Collaborative induction of inflammatory responses by dectin-1 and Tolllike receptor 2
    • Gantner, B. N., R. M. Simmons, S. J. Canavera, S. Akira, and D. M. Underhill. 2003. Collaborative induction of inflammatory responses by dectin-1 and Tolllike receptor 2. J. Exp. Med. 197: 1107-1117.
    • (2003) J. Exp. Med. , vol.197 , pp. 1107-1117
    • Gantner, B.N.1    Simmons, R.M.2    Canavera, S.J.3    Akira, S.4    Underhill, D.M.5
  • 15
    • 0033592748 scopus 로고    scopus 로고
    • The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens
    • Underhill, D. M., A. Ozinsky, A. M. Hajjar, A. Stevens, C. B. Wilson, M. Bassetti, and A. Aderem. 1999. The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens. Nature 401: 811-815.
    • (1999) Nature , vol.401 , pp. 811-815
    • Underhill, D.M.1    Ozinsky, A.2    Hajjar, A.M.3    Stevens, A.4    Wilson, C.B.5    Bassetti, M.6    Aderem, A.7
  • 19
    • 58849145188 scopus 로고    scopus 로고
    • Induction of innate immune response through TLR2 and dectin 1 prevents type 1 diabetes
    • Karumuthil-Melethil, S., N. Perez, R. Li, and C. Vasu. 2008. Induction of innate immune response through TLR2 and dectin 1 prevents type 1 diabetes. J. Immunol. 181: 8323-8334.
    • (2008) J. Immunol. , vol.181 , pp. 8323-8334
    • Karumuthil-Melethil, S.1    Perez, N.2    Li, R.3    Vasu, C.4
  • 20
    • 34548550594 scopus 로고    scopus 로고
    • Collaboration between the innate immune receptors dectin-1, TLRs, and Nods
    • Underhill, D. M. 2007. Collaboration between the innate immune receptors dectin-1, TLRs, and Nods. Immunol. Rev. 219: 75-87.
    • (2007) Immunol. Rev. , vol.219 , pp. 75-87
    • Underhill, D.M.1
  • 21
    • 64149088746 scopus 로고    scopus 로고
    • Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity
    • Manicassamy, S., R. Ravindran, J. Deng, H. Oluoch, T. L. Denning, S. P. Kasturi, K. M. Rosenthal, B. D. Evavold, and B. Pulendran. 2009. Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity. Nat. Med. 15: 401-409.
    • (2009) Nat. Med. , vol.15 , pp. 401-409
    • Manicassamy, S.1    Ravindran, R.2    Deng, J.3    Oluoch, H.4    Denning, T.L.5    Kasturi, S.P.6    Rosenthal, K.M.7    Evavold, B.D.8    Pulendran, B.9
  • 22
    • 32244442562 scopus 로고    scopus 로고
    • TGFβ in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
    • Veldhoen, M., R. J. Hocking, C. J. Atkins, R. M. Locksley, and B. Stockinger. 2006. TGFβ in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 24: 179-189.
    • (2006) Immunity , vol.24 , pp. 179-189
    • Veldhoen, M.1    Hocking, R.J.2    Atkins, C.J.3    Locksley, R.M.4    Stockinger, B.5
  • 24
    • 42649115767 scopus 로고    scopus 로고
    • TH17 cells in development: An updated view of their molecular identity and genetic programming
    • Dong, C. 2008. TH17 cells in development: an updated view of their molecular identity and genetic programming. Nat. Rev. Immunol. 8: 337-348.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 337-348
    • Dong, C.1
  • 25
    • 77954932467 scopus 로고    scopus 로고
    • Programming dendritic cells to induce T(H)2 and tolerogenic responses
    • Pulendran, B., H. Tang, and S. Manicassamy. 2010. Programming dendritic cells to induce T(H)2 and tolerogenic responses. Nat. Immunol. 11: 647-655.
    • (2010) Nat. Immunol. , vol.11 , pp. 647-655
    • Pulendran, B.1    Tang, H.2    Manicassamy, S.3
  • 28
    • 48749101937 scopus 로고    scopus 로고
    • WNT signalling in the immune system: WNT is spreading its wings
    • Staal, F. J., T. C. Luis, and M. M. Tiemessen. 2008. WNT signalling in the immune system: WNT is spreading its wings. Nat. Rev. Immunol. 8: 581-593.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 581-593
    • Staal, F.J.1    Luis, T.C.2    Tiemessen, M.M.3
  • 29
    • 67349206122 scopus 로고    scopus 로고
    • Notch and wingless signaling cooperate in regulation of dendritic cell differentiation
    • Zhou, J., P. Cheng, J. I. Youn, M. J. Cotter, and D. I. Gabrilovich. 2009. Notch and wingless signaling cooperate in regulation of dendritic cell differentiation. Immunity 30: 845-859.
    • (2009) Immunity , vol.30 , pp. 845-859
    • Zhou, J.1    Cheng, P.2    Youn, J.I.3    Cotter, M.J.4    Gabrilovich, D.I.5
  • 30
    • 34548448100 scopus 로고    scopus 로고
    • Gene expression profiling during differentiation of human monocytes to macrophages or dendritic cells
    • Lehtonen, A., H. Ahlfors, V. Veckman, M. Miettinen, R. Lahesmaa, and I. Julkunen. 2007. Gene expression profiling during differentiation of human monocytes to macrophages or dendritic cells. J. Leukoc. Biol. 82: 710-720.
    • (2007) J. Leukoc. Biol. , vol.82 , pp. 710-720
    • Lehtonen, A.1    Ahlfors, H.2    Veckman, V.3    Miettinen, M.4    Lahesmaa, R.5    Julkunen, I.6
  • 34
    • 0035914388 scopus 로고    scopus 로고
    • Akt1/ PKBa is required for normal growth but dispensable for maintenance of glucose homeostasis in mice
    • Cho, H., J. L. Thorvaldsen, Q. Chu, F. Feng, and M. J. Birnbaum. 2001. Akt1/ PKBa is required for normal growth but dispensable for maintenance of glucose homeostasis in mice. J. Biol. Chem. 276: 38349-38352.
    • (2001) J. Biol. Chem. , vol.276 , pp. 38349-38352
    • Cho, H.1    Thorvaldsen, J.L.2    Chu, Q.3    Feng, F.4    Birnbaum, M.J.5
  • 35
    • 79953215305 scopus 로고    scopus 로고
    • T-cell factor 4 functions as a tumor suppressor whose disruption modulates colon cell proliferation and tumorigenesis
    • Angus-Hill, M. L., K. M. Elbert, J. Hidalgo, and M. R. Capecchi. 2011. T-cell factor 4 functions as a tumor suppressor whose disruption modulates colon cell proliferation and tumorigenesis. Proc. Natl. Acad. Sci. USA 108: 4914-4919.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 4914-4919
    • Angus-Hill, M.L.1    Elbert, K.M.2    Hidalgo, J.3    Capecchi, M.R.4
  • 36
    • 34447275920 scopus 로고    scopus 로고
    • Notch-RBP-J signaling controls the homeostasis of CD8-dendritic cells in the spleen
    • Caton, M. L., M. R. Smith-Raska, and B. Reizis. 2007. Notch-RBP-J signaling controls the homeostasis of CD8-dendritic cells in the spleen. J. Exp. Med. 204: 1653-1664.
    • (2007) J. Exp. Med. , vol.204 , pp. 1653-1664
    • Caton, M.L.1    Smith-Raska, M.R.2    Reizis, B.3
  • 37
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling in development and disease
    • Clevers, H. 2006. Wnt/β-catenin signaling in development and disease. Cell 127: 469-480.
    • (2006) Cell , vol.127 , pp. 469-480
    • Clevers, H.1
  • 40
    • 84866177483 scopus 로고    scopus 로고
    • Cutting edge: 4-1BB controls regulatory activity in dendritic cells through promoting optimal expression of retinal dehydrogenase
    • Lee, S. W., Y. Park, S. Y. Eun, S. Madireddi, H. Cheroutre, and M. Croft. 2012. Cutting edge: 4-1BB controls regulatory activity in dendritic cells through promoting optimal expression of retinal dehydrogenase. J. Immunol. 189: 2697-2701.
    • (2012) J. Immunol. , vol.189 , pp. 2697-2701
    • Lee, S.W.1    Park, Y.2    Eun, S.Y.3    Madireddi, S.4    Cheroutre, H.5    Croft, M.6
  • 41
    • 78650178058 scopus 로고    scopus 로고
    • Continuous expression of the transcription factor e2-2 maintains the cell fate of mature plasmacytoid dendritic cells
    • Ghosh, H. S., B. Cisse, A. Bunin, K. L. Lewis, and B. Reizis. 2010. Continuous expression of the transcription factor e2-2 maintains the cell fate of mature plasmacytoid dendritic cells. Immunity 33: 905-916.
    • (2010) Immunity , vol.33 , pp. 905-916
    • Ghosh, H.S.1    Cisse, B.2    Bunin, A.3    Lewis, K.L.4    Reizis, B.5
  • 42
    • 0035034603 scopus 로고    scopus 로고
    • Inactivation of the β-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development
    • Brault, V., R. Moore, S. Kutsch, M. Ishibashi, D. H. Rowitch, A. P. McMahon, L. Sommer, O. Boussadia, and R. Kemler. 2001. Inactivation of the β-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development 128: 1253-1264.
    • (2001) Development , vol.128 , pp. 1253-1264
    • Brault, V.1    Moore, R.2    Kutsch, S.3    Ishibashi, M.4    Rowitch, D.H.5    McMahon, A.P.6    Sommer, L.7    Boussadia, O.8    Kemler, R.9
  • 44
    • 84866179288 scopus 로고    scopus 로고
    • The Akt1 isoform is required for optimal IFN-b transcription through direct phosphorylation of β-catenin
    • Gantner, B. N., H. Jin, F. Qian, N. Hay, B. He, and R. D. Ye. 2012. The Akt1 isoform is required for optimal IFN-b transcription through direct phosphorylation of β-catenin. J. Immunol. 189: 3104-3111.
    • (2012) J. Immunol. , vol.189 , pp. 3104-3111
    • Gantner, B.N.1    Jin, H.2    Qian, F.3    Hay, N.4    He, B.5    Ye, R.D.6
  • 45
    • 77952566304 scopus 로고    scopus 로고
    • The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type i interferon via a β-catenin-dependent pathway
    • Yang, P., H. An, X. Liu, M. Wen, Y. Zheng, Y. Rui, and X. Cao. 2010. The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a β-catenin-dependent pathway. Nat. Immunol. 11: 487-494.
    • (2010) Nat. Immunol. , vol.11 , pp. 487-494
    • Yang, P.1    An, H.2    Liu, X.3    Wen, M.4    Zheng, Y.5    Rui, Y.6    Cao, X.7
  • 46
    • 80052966977 scopus 로고    scopus 로고
    • Interplay between foxo, tor, and akt
    • Hay, N. 2011. Interplay between FOXO, TOR, and Akt. Biochim. Biophys. Acta 1813: 1965-1970.
    • (2011) Biochim. Biophys. Acta , vol.1813 , pp. 1965-1970
    • Hay, N.1
  • 47
    • 78049369030 scopus 로고    scopus 로고
    • Roles for TGF-β and programmed cell death 1 ligand 1 in regulatory T cell expansion and diabetes suppression by zymosan in nonobese diabetic mice
    • Burton, O. T., P. Zaccone, J. M. Phillips, H. De La Peña, Z. Fehérvári, M. Azuma, S. Gibbs, B. Stockinger, and A. Cooke. 2010. Roles for TGF-β and programmed cell death 1 ligand 1 in regulatory T cell expansion and diabetes suppression by zymosan in nonobese diabetic mice. J. Immunol. 185: 2754-2762.
    • (2010) J. Immunol. , vol.185 , pp. 2754-2762
    • Burton, O.T.1    Zaccone, P.2    Phillips, J.M.3    De La Peña, H.4    Fehérvári, Z.5    Azuma, M.6    Gibbs, S.7    Stockinger, B.8    Cooke, A.9
  • 48
    • 84873488653 scopus 로고    scopus 로고
    • TLR-2 activation induces regulatory T cells and long-term suppression of asthma manifestations in mice
    • Nawijn, M. C., A. C. Motta, R. Gras, S. Shirinbak, H. Maazi, and A. J. van Oosterhout. 2013. TLR-2 activation induces regulatory T cells and long-term suppression of asthma manifestations in mice. PLoS One 8: e55307.
    • (2013) PLoS One , vol.8 , pp. e55307
    • Nawijn, M.C.1    Motta, A.C.2    Gras, R.3    Shirinbak, S.4    Maazi, H.5    Van Oosterhout, A.J.6
  • 50
    • 34247555353 scopus 로고    scopus 로고
    • Differentiation and function of Th17 T cells
    • Stockinger, B., and M. Veldhoen. 2007. Differentiation and function of Th17 T cells. Curr. Opin. Immunol. 19: 281-286.
    • (2007) Curr. Opin. Immunol. , vol.19 , pp. 281-286
    • Stockinger, B.1    Veldhoen, M.2
  • 53
    • 84879114342 scopus 로고    scopus 로고
    • Canonical and noncanonical Wnt proteins program dendritic cell responses for tolerance
    • Oderup, C., M. LaJevic, and E. C. Butcher. 2013. Canonical and noncanonical Wnt proteins program dendritic cell responses for tolerance. J. Immunol. 190: 6126-6134.
    • (2013) J. Immunol. , vol.190 , pp. 6126-6134
    • Oderup, C.1    Lajevic, M.2    Butcher, E.C.3
  • 54
    • 35748968209 scopus 로고    scopus 로고
    • In vitro induction of mucosa-type dendritic cells by all-trans retinoic acid
    • Saurer, L., K. C. McCullough, and A. Summerfield. 2007. In vitro induction of mucosa-type dendritic cells by all-trans retinoic acid. J. Immunol. 179: 3504-3514.
    • (2007) J. Immunol. , vol.179 , pp. 3504-3514
    • Saurer, L.1    McCullough, K.C.2    Summerfield, A.3
  • 55
    • 34248169760 scopus 로고    scopus 로고
    • 9-cis-Retinoic acid (9cRA), a retinoid X receptor (RXR) ligand, exerts immunosuppressive effects on dendritic cells by RXR-dependent activation: Inhibition of peroxisome proliferator-activated receptor g blocks some of the 9cRA activities, and precludes them to mature phenotype development
    • Zapata-Gonzalez, F., F. Rueda, J. Petriz, P. Domingo, F. Villarroya, A. de Madariaga, and J. C. Domingo. 2007. 9-cis-Retinoic acid (9cRA), a retinoid X receptor (RXR) ligand, exerts immunosuppressive effects on dendritic cells by RXR-dependent activation: inhibition of peroxisome proliferator-activated receptor g blocks some of the 9cRA activities, and precludes them to mature phenotype development. J. Immunol. 178: 6130-6139.
    • (2007) J. Immunol. , vol.178 , pp. 6130-6139
    • Zapata-Gonzalez, F.1    Rueda, F.2    Petriz, J.3    Domingo, P.4    Villarroya, F.5    De Madariaga, A.6    Domingo, J.C.7
  • 57
    • 33745834029 scopus 로고    scopus 로고
    • Effect of all-trans-retinoic acid on the differentiation, maturation and functions of dendritic cells derived from cord blood monocytes
    • Tao, Y., Y. Yang, and W. Wang. 2006. Effect of all-trans-retinoic acid on the differentiation, maturation and functions of dendritic cells derived from cord blood monocytes. FEMS Immunol. Med. Microbiol. 47: 444-450.
    • (2006) FEMS Immunol. Med. Microbiol. , vol.47 , pp. 444-450
    • Tao, Y.1    Yang, Y.2    Wang, W.3
  • 58
    • 78650642949 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase activation attenuates the TLR2-mediated macrophage proinflammatory cytokine response to Francisella tularensis live vaccine strain
    • Medina, E. A., I. R. Morris, and M. T. Berton. 2010. Phosphatidylinositol 3-kinase activation attenuates the TLR2-mediated macrophage proinflammatory cytokine response to Francisella tularensis live vaccine strain. J. Immunol. 185: 7562-7572.
    • (2010) J. Immunol. , vol.185 , pp. 7562-7572
    • Medina, E.A.1    Morris, I.R.2    Berton, M.T.3
  • 60
    • 0037629646 scopus 로고    scopus 로고
    • PI3K and negative regulation of TLR signaling
    • Fukao, T., and S. Koyasu. 2003. PI3K and negative regulation of TLR signaling. Trends Immunol. 24: 358-363.
    • (2003) Trends Immunol. , vol.24 , pp. 358-363
    • Fukao, T.1    Koyasu, S.2
  • 61
    • 33646471083 scopus 로고    scopus 로고
    • TLR5-mediated phosphoinositide 3-kinase activation negatively regulates flagellininduced proinflammatory gene expression
    • Yu, Y., S. Nagai, H. Wu, A. S. Neish, S. Koyasu, and A. T. Gewirtz. 2006. TLR5-mediated phosphoinositide 3-kinase activation negatively regulates flagellininduced proinflammatory gene expression. J. Immunol. 176: 6194-6201.
    • (2006) J. Immunol. , vol.176 , pp. 6194-6201
    • Yu, Y.1    Nagai, S.2    Wu, H.3    Neish, A.S.4    Koyasu, S.5    Gewirtz, A.T.6
  • 62
    • 0037199972 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells
    • Guha, M., and N. Mackman. 2002. The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells. J. Biol. Chem. 277: 32124-32132.
    • (2002) J. Biol. Chem. , vol.277 , pp. 32124-32132
    • Guha, M.1    Mackman, N.2
  • 63
    • 0038446051 scopus 로고    scopus 로고
    • Role of the phosphatidylinositol 3 kinase-Akt pathway in the regulation of IL-10 and IL-12 by Porphyromonas gingivalis lipopolysaccharide
    • Martin, M., R. E. Schifferle, N. Cuesta, S. N. Vogel, J. Katz, and S. M. Michalek. 2003. Role of the phosphatidylinositol 3 kinase-Akt pathway in the regulation of IL-10 and IL-12 by Porphyromonas gingivalis lipopolysaccharide. J. Immunol. 171: 717-725.
    • (2003) J. Immunol. , vol.171 , pp. 717-725
    • Martin, M.1    Schifferle, R.E.2    Cuesta, N.3    Vogel, S.N.4    Katz, J.5    Michalek, S.M.6
  • 64
    • 74549167783 scopus 로고    scopus 로고
    • Regulation of adaptive immunity by the innate immune system
    • Iwasaki, A., and R. Medzhitov. 2010. Regulation of adaptive immunity by the innate immune system. Science 327: 291-295.
    • (2010) Science , vol.327 , pp. 291-295
    • Iwasaki, A.1    Medzhitov, R.2
  • 65
    • 79956311926 scopus 로고    scopus 로고
    • The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota
    • Round, J. L., S. M. Lee, J. Li, G. Tran, B. Jabri, T. A. Chatila, and S. K. Mazmanian. 2011. The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota. Science 332: 974-977.
    • (2011) Science , vol.332 , pp. 974-977
    • Round, J.L.1    Lee, S.M.2    Li, J.3    Tran, G.4    Jabri, B.5    Chatila, T.A.6    Mazmanian, S.K.7
  • 66
    • 77954738601 scopus 로고    scopus 로고
    • + regulatory T-cell development by a commensal bacterium of the intestinal microbiota
    • Round, J. L., and S. K. Mazmanian. 2010. Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota. Proc. Natl. Acad. Sci. USA 107: 12204-12209.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 12204-12209
    • Round, J.L.1    Mazmanian, S.K.2
  • 67
    • 84867656021 scopus 로고    scopus 로고
    • Outer membrane vesicles of a human commensal mediate immune regulation and disease protection
    • Shen, Y., M. L. Giardino Torchia, G. W. Lawson, C. L. Karp, J. D. Ashwell, and S. K. Mazmanian. 2012. Outer membrane vesicles of a human commensal mediate immune regulation and disease protection. Cell Host Microbe 12: 509-520.
    • (2012) Cell Host Microbe , vol.12 , pp. 509-520
    • Shen, Y.1    Torchia, M.L.G.2    Lawson, G.W.3    Karp, C.L.4    Ashwell, J.D.5    Mazmanian, S.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.