메뉴 건너뛰기




Volumn 110, Issue 4, 2011, Pages 892-900

Chronic heart failure reduces Akt phosphorylation in human skeletal muscle: Relationship to muscle size and function

Author keywords

Atrophy; Cachexia; Myosin; Sarcopenia

Indexed keywords

EIF4EBP1 PROTEIN, HUMAN; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; PHOSPHOPROTEIN; PROTEIN KINASE B; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SOMATOMEDIN C; TARGET OF RAPAMYCIN KINASE;

EID: 79954607087     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00545.2010     Document Type: Article
Times cited : (37)

References (60)
  • 1
    • 15444369228 scopus 로고    scopus 로고
    • Resistance training increases total daily energy expenditure in disabled older women with coronary heart disease
    • DOI 10.1152/japplphysiol.00360.2004
    • Ades PA, Savage PD, Brochu M, Tischler MD, Lee NM, Poehlman ET. Resistance training increases total daily energy expenditure in disabled older women with coronary disease. J Appl Physiol 98: 1280-1285, 2005. (Pubitemid 40396501)
    • (2005) Journal of Applied Physiology , vol.98 , Issue.4 , pp. 1280-1285
    • Ades, P.A.1    Savage, P.D.2    Brochu, M.3    Tischler, M.D.4    Lee, N.M.5    Poehlman, E.T.6
  • 7
    • 0037381535 scopus 로고    scopus 로고
    • Defective signaling through Akt-2 and -3 but not Akt-1 in insulin-resistant human skeletal muscle: Potential role in insulin resistance
    • DOI 10.2337/diabetes.52.4.935
    • Brozinick JT, Roberts BR, Dohm GL. Defective signaling through Akt-2 and -3 but not Akt-1 in insulin-resistant human skeletal muscle. Diabetes 52: 935-941, 2003. (Pubitemid 36384263)
    • (2003) Diabetes , vol.52 , Issue.4 , pp. 935-941
    • Brozinick Jr., J.T.1    Roberts, B.R.2    Dohm, G.L.3
  • 8
    • 1942469564 scopus 로고    scopus 로고
    • 2446 Is a Novel Mammalian Target of Rapamycin (mTOR) Phosphorylation Site Regulated by Nutrient Status
    • DOI 10.1074/jbc.C300534200
    • Cheng SWY, Fryer LGD, Carling D, Shepherd PR. Thr2446 Is a novel mammalian target of rapamycin (mTOR) phosphorylation site regulated by nutrient status. J Biol Chem 279: 15719-15722, 2004. (Pubitemid 38509255)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.16 , pp. 15719-15722
    • Cheng, S.W.Y.1    Fryer, L.G.D.2    Carling, D.3    Shepherd, P.R.4
  • 9
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • DOI 10.1038/378785a0
    • Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378: 785-789, 1995. (Pubitemid 26004411)
    • (1995) Nature , vol.378 , Issue.6559 , pp. 785-789
    • Cross, D.A.E.1    Alessi, D.R.2    Cohen, P.3    Andjelkovich, M.4    Hemmings, B.A.5
  • 13
    • 0019508224 scopus 로고
    • Relation of the renin-angiotensin-aldosterone system to clinical state in congestive heart failure
    • Dzau VJ, Colucci WS, Hollenberg NK, Williams GH. Relation of the renin-angiotensin-aldosterone system to clinical state in congestive heart failure. Circulation 63: 645-651, 1981. (Pubitemid 11139875)
    • (1981) Circulation , vol.63 , Issue.3 , pp. 645-651
    • Dzau, V.J.1    Colucci, W.S.2    Hollenberg, N.K.3    Williams, G.H.4
  • 15
    • 0037097863 scopus 로고    scopus 로고
    • Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E
    • DOI 10.1101/gad.995802
    • Fingar DC, Salama S, Tsou C, Harlow E, Blenis J. Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/ eIF4E. Genes Dev 16: 1472-1487, 2002. (Pubitemid 34686329)
    • (2002) Genes and Development , vol.16 , Issue.12 , pp. 1472-1487
    • Fingar, D.C.1    Salama, S.2    Tsou, C.3    Harlow, E.4    Blenis, J.5
  • 16
    • 34447644976 scopus 로고    scopus 로고
    • Protein kinase B/Akt: A nexus of growth factor and cytokine signaling in determining muscle mass
    • DOI 10.1152/japplphysiol.00089.2007
    • Frost RA, Lang CH. Protein kinase B/Akt: A nexus of growth and cytokine signaling in determining muscle mass. J Appl Physiol 103: 378-387, 2007. (Pubitemid 47092315)
    • (2007) Journal of Applied Physiology , vol.103 , Issue.1 , pp. 378-387
    • Frost, R.A.1    Lang, C.H.2
  • 17
    • 0033871523 scopus 로고    scopus 로고
    • Maximum specific force depends on myosin heavy chain content in rat diaphragm muscle fibers
    • Geiger PC, Cody MJ, Macken RL, Sieck GC. Maximum specific force depends on myosin heavy chain content in rat diaphragm muscle fibers. J Appl Physiol 89: 695-703, 2000. (Pubitemid 30637120)
    • (2000) Journal of Applied Physiology , vol.89 , Issue.2 , pp. 695-703
    • Geiger, P.C.1    Cody, M.J.2    Macken, R.L.3    Sieck, G.C.4
  • 18
    • 33751348056 scopus 로고    scopus 로고
    • Ablation in Mice of the mTORC Components raptor, rictor, or mLST8 Reveals that mTORC2 Is Required for Signaling to Akt-FOXO and PKCα, but Not S6K1
    • DOI 10.1016/j.devcel.2006.10.007, PII S153458070600459X
    • Guertin DA, Stevens DM, Thoreen CC, Burds AA, Kalaany NY, Moffat J, Brown M, Fitzgerald KJ, Sabatini DM. Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 Is required for signaling to Akt-FOXO and PKC[alpha], but not S6K1. Dev Cell 11: 859-871, 2006. (Pubitemid 44804279)
    • (2006) Developmental Cell , vol.11 , Issue.6 , pp. 859-871
    • Guertin, D.A.1    Stevens, D.M.2    Thoreen, C.C.3    Burds, A.A.4    Kalaany, N.Y.5    Moffat, J.6    Brown, M.7    Fitzgerald, K.J.8    Sabatini, D.M.9
  • 21
    • 1542269757 scopus 로고    scopus 로고
    • The effect of recombinant human growth hormone and resistance training on IGF-I mRNA expression in the muscles of elderly men
    • DOI 10.1113/jphysiol.2003.051722
    • Hameed M, Lange KHW, Anderson JL, Schjerling P, Kjaer M, Harridge SDR, Goldspink G. The effect of recombinant human growth hormone and resistance training on IGF-I mRNA expression in the muscles of elderly men. J Physiol 555: 231-240, 2004. (Pubitemid 38313073)
    • (2004) Journal of Physiology , vol.555 , Issue.1 , pp. 231-240
    • Hameed, M.1    Lange, K.H.W.2    Andersen, J.L.3    Schjerling, P.4    Kjaer, M.5    Harridge, S.D.R.6    Goldspink, G.7
  • 22
    • 0037440667 scopus 로고    scopus 로고
    • Expression of IGF-I splice variants in young and old human skeletal muscle after high resistance exercise
    • DOI 10.1113/jphysiol.2002.032136
    • Hameed M, Orrell RW, Cobbold M, Goldspink G, Harridge SDR. Expression of IGF-I splice variants in young and old human skeletal muscle after high resistance exercise. J Physiol 547: 247-254, 2003. (Pubitemid 36285178)
    • (2003) Journal of Physiology , vol.547 , Issue.1 , pp. 247-254
    • Hameed, M.1    Orrell, R.W.2    Cubbold, M.3    Goldspink, G.4    Harridge, S.D.R.5
  • 23
    • 0030781804 scopus 로고    scopus 로고
    • Skeletal muscle abnormalities and evidence for their role in symptom generation in chronic heart failure
    • Harrington D, Coats AJ. Skeletal muscle abnormalities and evidence for their role in symptom generation in chronic heart failure. Eur Heart J 18: 1865-1872, 1997. (Pubitemid 27526116)
    • (1997) European Heart Journal , vol.18 , Issue.12 , pp. 1865-1872
    • Harrington, D.1    Coats, A.J.S.2
  • 26
    • 33749076673 scopus 로고    scopus 로고
    • SIN1/MIP1 Maintains rictor-mTOR Complex Integrity and Regulates Akt Phosphorylation and Substrate Specificity
    • DOI 10.1016/j.cell.2006.08.033, PII S0092867406011470
    • Jacinto E, Facchinetti V, Liu D, Soto N, Wei S, Jung SY, Huang Q, Qin J, Su B. SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell 127: 125-137, 2006. (Pubitemid 44466632)
    • (2006) Cell , vol.127 , Issue.1 , pp. 125-137
    • Jacinto, E.1    Facchinetti, V.2    Liu, D.3    Soto, N.4    Wei, S.5    Jung, S.Y.6    Huang, Q.7    Qin, J.8    Su, B.9
  • 28
    • 0032698470 scopus 로고    scopus 로고
    • Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes
    • Kim YB, Nikoulina SE, Ciaraldi TP, Henry RR, Kahn BB. Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes. J Clin Invest 104: 733-741, 1999. (Pubitemid 29536358)
    • (1999) Journal of Clinical Investigation , vol.104 , Issue.6 , pp. 733-741
    • Kim, Y.-B.1    Nikoulina, S.E.2    Ciaraldi, T.P.3    Henry, R.R.4    Kahn, B.B.5
  • 31
    • 39449100832 scopus 로고    scopus 로고
    • Human sarcopenia reveals an increase in SOCS-3 and myostatin and a reduced efficiency of Akt phosphorylation
    • Leger B, Derave W, De Bock K, Hespel P, Russell AP. Human sarcopenia reveals an increase in SOCS-3 and myostatin and a reduced efficiency of Akt phosphorylation. Rejuv Res 11: 163-175B, 2008.
    • (2008) Rejuv Res , vol.11
    • Leger, B.1    Derave, W.2    De Bock, K.3    Hespel, P.4    Russell, A.P.5
  • 32
    • 67650258512 scopus 로고    scopus 로고
    • Atrogin-1 MuRF-1 and FoXO, as well as phosphorylated GSK-3beta and 4E-BP1 are reduced in skeletal muscle of chronic spinal cord-injured patients
    • Leger B, Senese R, Al-Khodairy AW, Deriaz O, Gobelet C, Giacobino JP, Russell AP. Atrogin-1, MuRF-1, and FoXO, as well as phosphorylated GSK-3beta and 4E-BP1 are reduced in skeletal muscle of chronic spinal cord-injured patients. Muscle Nerve 40: 69-78, 2009.
    • (2009) Muscle Nerve , vol.40 , pp. 69-78
    • Leger, B.1    Senese, R.2    Al-Khodairy, A.W.3    Deriaz, O.4    Gobelet, C.5    Giacobino, J.P.6    Russell, A.P.7
  • 33
    • 33645807350 scopus 로고    scopus 로고
    • Human skeletal muscle atrophy in amyotrophic lateral sclerosis reveals a reduction in Akt and an increase in atrogin-1
    • DOI 10.1096/fj.05-5249fje
    • Leger B, Vergani L, Soraru G, Hespel P, Gobelet C, D'Ascenzio C, Angelini C, Russell AP. Human skeletal muscle atrophy in amyotrophic lateral sclerosis reveals a reduction in Akt and an increase in atrogin-1. FASEB J 20: 583-585, 2006. (Pubitemid 46671257)
    • (2006) FASEB Journal , vol.20 , Issue.3 , pp. 583-585
    • Leger, B.1    Vergani, L.2    Soraru, G.3    Hespel, P.4    Derave, W.5    Gobelet, C.6    D'Ascenzio, C.7    Angelini, C.8    Russell, A.P.9
  • 36
    • 0026092505 scopus 로고
    • Value of peak exercise oxygen consumption for optimal timing of cardiac transplantation in ambulatory patients with heart failure
    • Mancini DM, Eisen H, Kussmaul W, Mull R, Edmunds LH, Wilson JR. Value of peak exercise oxygen consumption for optimal timing of cardiac transplantation in ambulatory patients with heart failure. Circulation 83: 778-786, 1991.
    • (1991) Circulation , vol.83 , pp. 778-786
    • Mancini, D.M.1    Eisen, H.2    Kussmaul, W.3    Mull, R.4    Edmunds, L.H.5    Wilson, J.R.6
  • 37
    • 34250788809 scopus 로고    scopus 로고
    • AKT/PKB Signaling: Navigating Downstream
    • DOI 10.1016/j.cell.2007.06.009, PII S0092867407007751
    • Manning BD, Cantley LC. AKT/PKB signaling: Navigating downstream. Cell 129: 1261-1274, 2007. (Pubitemid 46962095)
    • (2007) Cell , vol.129 , Issue.7 , pp. 1261-1274
    • Manning, B.D.1    Cantley, L.C.2
  • 40
    • 23944480371 scopus 로고    scopus 로고
    • Molecular determinants of skeletal muscle mass: Getting the "AKT" together
    • DOI 10.1016/j.biocel.2005.02.026, PII S1357272505000774
    • Nader GA. Molecular determinants of skeletal muscle mass: Getting the "AKT" together. Int J Biochem Cell Biol 37: 1985-1996, 2005. (Pubitemid 41206816)
    • (2005) International Journal of Biochemistry and Cell Biology , vol.37 , Issue.10 SPEC. ISS. , pp. 1985-1996
    • Nader, G.A.1
  • 42
    • 84941816129 scopus 로고
    • Cardiac disability. The impact of coronary heart disease on patient's daily activities
    • DOI 10.1001/archinte.145.9.1642
    • Neill WA, Branch LG, DeJong G. Cardiac disability-the impact of coronary disease on patients' daily activities. Arch Intern Med 145: 1642-1647, 1985. (Pubitemid 16258206)
    • (1985) Archives of Internal Medicine , vol.145 , Issue.9 , pp. 1642-1647
    • Neill, W.A.1    Branch, L.G.2    De Jong, G.3
  • 43
    • 0025123554 scopus 로고
    • The Framingham disability study: Relationship of various coronary heart disease manifestations to disability in older persons liniving in the community
    • Pinsky JL, Jette AM, Branch LG, Kannel WB, Feinleib M. The Framingham Disability Study: Relationship of various coronary heart disease manifestations to disability in older persons living in the community. Am J Public Health 80: 1363-1368, 1990. (Pubitemid 20375556)
    • (1990) American Journal of Public Health , vol.80 , Issue.11 , pp. 1363-1368
    • Pinsky, J.L.1    Jette, A.M.2    Branch, L.G.3    Kannel, W.B.4    Feinleib, M.5
  • 46
    • 11144356337 scopus 로고    scopus 로고
    • Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy
    • DOI 10.1016/S0092-8674(04)00400-3, PII S0092867404004003
    • Sandri M, Sandri C, Gilbert A, Skurk C, Calabria E, Picard A, Walsh K, Schiaffino S, Lecker SH, Goldberg AL. Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy. Cell 177: 399-412, 2004. (Pubitemid 38534545)
    • (2004) Cell , vol.117 , Issue.3 , pp. 399-412
    • Sandri, M.1    Sandri, C.2    Gilbert, A.3    Skurk, C.4    Calabria, E.5    Picard, A.6    Walsh, K.7    Schiaffino, S.8    Lecker, S.H.9    Goldberg, A.L.10
  • 47
    • 24744446252 scopus 로고    scopus 로고
    • Transgenic overexpression of locally acting insulin-like growth factor-1 inhibits ubiquitin-mediated muscle atrophy in chronic left-ventricular dysfunction
    • DOI 10.1161/01.RES.0000179580.72375.c2
    • Schulze PC, Fang J, Kassik KA, Gannon J, Cupesi M, MacGillivray C, Lee RT, Rosenthal N. Transgenic overexpression of locally acting insulin-like growth factor-1 inhibits ubiquitin-mediated muscle atrophy in chronic left-ventricular dysfunction. Circ Res 97: 418-426, 2005. (Pubitemid 41298171)
    • (2005) Circulation Research , vol.97 , Issue.5 , pp. 418-426
    • Schulze, P.C.1    Fang, J.2    Kassik, K.A.3    Gannon, J.4    Cupesi, M.5    MacGillivray, C.6    Lee, R.T.7    Rosenthal, N.8
  • 51
    • 2042425906 scopus 로고    scopus 로고
    • The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors
    • DOI 10.1016/S1097-2765(04)00211-4, PII S1097276504002114
    • Stitt TN, Drujan D, Clarke BA, Panaro F, Timofeyva Y, Kline WO, Gonzalez M, Yancopoulos GD, Glass DJ. The IGF/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors. Mol Cell 14: 395-403, 2004. (Pubitemid 38591410)
    • (2004) Molecular Cell , vol.14 , Issue.3 , pp. 395-403
    • Stitt, T.N.1    Drujan, D.2    Clarke, B.A.3    Panaro, F.4    Timofeyva, Y.5    Kline, W.O.6    Gonzalez, M.7    Yancopoulos, G.D.8    Glass, D.J.9
  • 53
    • 33644826416 scopus 로고    scopus 로고
    • Skeletal muscle myofibrillar mRNA expression in heart failure: Relationship to local and circulating hormones
    • DOI 10.1152/japplphysiol.00570.2005
    • Toth MJ, Ades PA, LeWinter MM, Tracy RP, Tchernof A. Skeletal muscle myofibrillar mRNA expression in heart failure: Relationship to local and circulating hormones. J Appl Physiol 100: 35-41, 2006. (Pubitemid 43671087)
    • (2006) Journal of Applied Physiology , vol.100 , Issue.1 , pp. 35-41
    • Toth, M.J.1    Ades, P.A.2    LeWinter, M.M.3    Tracy, R.P.4    Tchernof, A.5
  • 59
    • 0032498112 scopus 로고    scopus 로고
    • Regulation of eukaryotic initiation factor eIF2B: Glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin
    • DOI 10.1016/S0014-5793(97)01548-2, PII S0014579397015482
    • Welsh GI, Miller CM, Loughlin AJ, Price NT, Proud CG. Regulation of eukaryotic intiation factor eIF2B: Glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin. FEBS Lett 421: 125-130, 1998. (Pubitemid 28288076)
    • (1998) FEBS Letters , vol.421 , Issue.2 , pp. 125-130
    • Welsh, G.I.1    Miller, C.M.2    Loughlin, A.J.3    Price, N.T.4    Proud, C.G.5
  • 60
    • 0021112289 scopus 로고
    • Quantitative determination of myosin and actin in rabbit skeletal muscle
    • Yates LD, Greaser ML. Quantitative determination of myosin and actin in rabbit skeletal muscle. J Mol Biol 168: 123-141, 1983.
    • (1983) J Mol Biol , vol.168 , pp. 123-141
    • Yates, L.D.1    Greaser, M.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.