Preparation and characterisation of Kolliphor®P 188 and P 237 solid dispersion oral tablets containing the poorly water soluble drug disulfiram

International Journal of Pharmaceutics

Volumn 475, Issue 1, 2014, Pages 514-522

  Ramadhani, Nisrina ^a   Shabir, Mehwish ^a   McConville, Christopher ^a  

^a UNIVERSITY OF WOLVERHAMPTON   (United Kingdom)

Author keywords

Disulfiram; Hot melt; Solid dispersion; Solubility enhancement; Solvent evaporation

Indexed keywords

DISULFIRAM; MAGNESIUM STEARATE; POLYMER; SOLVENT; POLOXAMER; TABLET;

ANGLE OF REPOSE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DISPERSION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG SOLUBILITY; ENTHALPY; EVAPORATION; FLOW KINETICS; HAUSNER RATIO; PARTICLE SIZE; POWDER; SCALE UP; SUSTAINED DRUG RELEASE; SYNTHESIS; TABLET; TABLET COMPRESSION; TABLET FORMULATION; TABLET MANUFACTURE; THERMOGRAPHY; VISCOSITY; CHEMISTRY; DIFFERENTIAL SCANNING CALORIMETRY; PHARMACEUTICS; PROCEDURES; SOLUBILITY; X RAY DIFFRACTION;

CALORIMETRY, DIFFERENTIAL SCANNING; DISULFIRAM; DRUG LIBERATION; POLOXAMER; SOLUBILITY; TABLETS; TECHNOLOGY, PHARMACEUTICAL; X-RAY DIFFRACTION;

EID: 84907261857     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.09.013     Document Type: Article

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