Development of novel fast-dissolving tacrolimus solid dispersion-loaded prolonged release tablet

European Journal of Pharmaceutical Sciences

Volumn 54, Issue 1, 2014, Pages 1-7

  Cho, Jung Hyun ^a   Kim, Yong Il ^a,b   Kim, Dong Wuk ^c   Yousaf, Abid Mehmood ^c   Kim, Jong Oh ^a   Woo, Jong Soo ^b   Yong, Chul Soon ^a   Choi, Han Gon ^a,c  

^a Yeungnam University   (South Korea)

^b Hanmi Pharmaceutical Co Ltd   (South Korea)

^c Hanyang University   (South Korea)

Author keywords

Bioequivalence in beagle dogs; Ethylcellulose; Fast dissolving solid dispersion; Hydroxypropyl methylcellulose; Prolonged release tablet; Tacrolimus

Indexed keywords

ETHYL CELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE; TACROLIMUS; TALC;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; DOG; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG RELEASE; DRUG SOLUBILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; TABLET FORMULATION; TIME TO MAXIMUM PLASMA CONCENTRATION;

BIOEQUIVALENCE IN BEAGLE DOGS; ETHYLCELLULOSE; FAST-DISSOLVING SOLID DISPERSION; HYDROXYPROPYL METHYLCELLULOSE; PROLONGED RELEASE TABLET; TACROLIMUS;

ADMINISTRATION, ORAL; ANIMALS; BETA-CYCLODEXTRINS; BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DIOCTYL SULFOSUCCINIC ACID; DOGS; DRUG CARRIERS; DRUG DESIGN; IMMUNOSUPPRESSIVE AGENTS; RATS; SOLUBILITY; TABLETS; TACROLIMUS; TALC;

EID: 84892687255     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2013.12.016     Document Type: Article

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