Plumbagin reduces human colon cancer cell survival by inducing cell cycle arrest and mitochondria-mediated apoptosis

International Journal of Oncology

Volumn 45, Issue 5, 2014, Pages 1913-1920

  Eldhose, Binil ^a,b   Gunawan, Mia ^b   Rahman, Mahbubur ^b   Latha, Mukalel S ^a   Notario, Vicente ^b  

^a MAHATMA GANDHI UNIVERSITY   (India)

^b GEORGETOWN UNIVERSITY   (United States)

Author keywords

Apoptosis; Cell cycle; Colorectal cancer; Medicinal herbs; Plumbagin

Indexed keywords

PLUMBAGIN; REACTIVE OXYGEN METABOLITE; ANTINEOPLASTIC AGENT; NAPHTHOQUINONE;

APOPTOSIS; ARTICLE; CANCER SURVIVAL; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL DEATH; CELL PROLIFERATION; CIRCULATING TUMOR CELL; COLON CANCER; CONTROLLED STUDY; DRUG CYTOTOXICITY; HCT116 CELL LINE; HUMAN; HUMAN CELL; MITOCHONDRION; PRIMARY TUMOR; CELL CYCLE CHECKPOINT; CELL SURVIVAL; COLONIC NEOPLASMS; DRUG EFFECTS; METABOLISM; PATHOLOGY;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL PROLIFERATION; CELL SURVIVAL; COLONIC NEOPLASMS; HCT116 CELLS; HUMANS; MITOCHONDRIA; NAPHTHOQUINONES; REACTIVE OXYGEN SPECIES;

EID: 84907200180     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2014.2592     Document Type: Article

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