Apoptosis inducing effect of Plumbagin on colonic cancer cells depends on expression of COX-2

PLoS ONE

Volumn 6, Issue 4, 2011, Pages

  Subramaniya, Bharathi Raja ^a   Srinivasan, Gayathri ^a   Sadullah, Sakeena Sadullah Mohammed ^a   Davis, Nimitha ^a   Subhadara, Lakshmi Baddi Reddi ^b   Halagowder, Devaraj ^a   Sivasitambaram, Niranjali Devaraj ^a  

^a UNIVERSITY OF MADRAS   (India)

^b ANNA UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CYCLIN D1; CYCLINE; CYCLOOXYGENASE 2; CYTOCHROME C; GLYCOGEN SYNTHASE KINASE 3BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PLUMBAGIN; PROTEIN KINASE B; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN RECEPTOR; ANTINEOPLASTIC AGENT; NAPHTHOQUINONE; PROSTAGLANDIN SYNTHASE INHIBITOR; SMALL INTERFERING RNA; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CELL STRAIN HCT15; CELL STRAIN HT29; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IC 50; PROTEIN EXPRESSION; BIOSYNTHESIS; CELL CYCLE; COLON TUMOR; COMET ASSAY; DRUG EFFECT; ENZYMOLOGY; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; METABOLISM; METHODOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE;

PLUMBAGINACEAE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; COLONIC NEOPLASMS; COMET ASSAY; CYCLOOXYGENASE 2; CYCLOOXYGENASE INHIBITORS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INHIBITORY CONCENTRATION 50; NAPHTHOQUINONES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; TETRAZOLIUM SALTS; THIAZOLES;

EID: 79955737810     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0018695     Document Type: Article

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