Cytotoxicity and apoptosis induced by a plumbagin derivative in estrogen positive MCF-7 breast cancer cells

Anti-Cancer Agents in Medicinal Chemistry

Volumn 14, Issue 1, 2014, Pages 170-180

  Sagar, Sunil ^a   Esau, Luke ^a   Moosa, Basem ^a   Khashab, Niveen M ^a   Bajic, Vladimir B ^a   Kaur, Mandeep ^a  

^a KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Saudi Arabia)

Author keywords

Anticancer; Apoptosis; Breast cancer; Caspase 3 7; Plumbagin

Indexed keywords

ACETYL PLUMBAGIN; BENZOATE PLUMBAGIN; CASPASE 3; CASPASE 7; COMPLEMENTARY DNA; CROTONATE PLUMBAGIN; ESTROGEN; ESTROGEN RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ISOBUTYRATE PLUMBAGIN; MESSENGER RNA; PLUMBAGIN; PROPIONATE PLUMBAGIN; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN MDM2; PROTEIN P53; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPERCENTAGE ASSAY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CELL CYCLE PARAMETERS; CONTROLLED STUDY; CYTOTOXICITY; DNA SYNTHESIS; ENZYME ACTIVITY; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; HUMAN; HUMAN CELL; MCF 7 CELL LINE; QUANTITATIVE ASSAY; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CASPASE 3; CASPASE 7; CELL CYCLE; CELL SURVIVAL; FEMALE; FIBROBLASTS; HEP G2 CELLS; HUMANS; MALE; MCF-7 CELLS; NAPHTHOQUINONES; REACTIVE OXYGEN SPECIES; RECEPTORS, ESTROGEN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84899462020     PISSN: 18715206     EISSN: 18755992     Source Type: Journal    
DOI: 10.2174/18715206113136660369     Document Type: Article

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