Niosomal Plumbagin with Reduced Toxicity and Improved Anticancer Activity in BALB/C Mice

Journal of Pharmacy and Pharmacology

Volumn 48, Issue 11, 1996, Pages 1128-1132

  Raja Naresh, R A ^a   Udupa, N ^a   Uma Devi, P ^a  

^a MANIPAL COLLEGE OF PHARMACEUTICAL SCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DRUG CARRIER; LIPOSOME; NAPHTHOQUINONE; PLUMBAGIN; SURFACTANT;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; CHEMISTRY; DOSE RESPONSE; DRUG SCREENING; EHRLICH ASCITES TUMOR; MICROCAPSULE; MOUSE; PATHOLOGY; SARCOMA 180;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CAPSULES; CARCINOMA, EHRLICH TUMOR; CHEMISTRY, PHARMACEUTICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG CARRIERS; DRUG SCREENING ASSAYS, ANTITUMOR; LIPOSOMES; MICE; MICE, INBRED BALB C; NAPHTHOQUINONES; SARCOMA 180; SURFACE-ACTIVE AGENTS;

EID: 0030276749     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-7158.1996.tb03907.x     Document Type: Article

References (21)

1. Alving, C. R. (1983) Delivery of liposome-encapsulated drugs to macrophages. Pharmacol. Ther. 22: 407-424
2. Azmin, M. N., Florence, A. T., Handjani Vila, R. M., Stewart, J. F., Vanlerberghe, G., Whittaker, J. S. (1985) The effect of non ionic surfactant vesicle (niosome) entrapment on the absorption and distribution of methotrexate in mice. J. Pharm. Pharmacol. 37: 237-242
3. Baillie, A. J., Florence, A. T., Hume, L. R., Muirhead, G. T., Rogerson, A. (1984) The effect of cholesterol on single chain, non-ionic surfactant vesicles. J. Pharm. Pharmacol (Suppl.) 36: 488P
4. Baillie, A. J., Florence, A. T., Hume, L. R., Muirhead, G. T., Rogerson, A. (1985) The preparation and properties of niosomes-non-ionic surfactant vesicles. J. Pharm. Pharmacol. 37: 863-868
5. Baillie, A. J., Coombs, G. H., Dolan, T. F., Laurio, J. (1986) Non ionic surfactant vesicle, niosomes, as delivery system for the anti-leishmanial drug, sodium stibogluconate. J. Pharm. Pharmacol. 38: 502-505
6. Carter, S. K. (1984) Some thoughts on resistance to cancer chemotherapy. Cancer Treat Rev. II (Suppl. A): 3-7
7. Couvreur, P., Kante, B., Lenaerts, V., Scaitteur, V., Ronald M., Speiser, P. (1980) Tissue distribution of antitumor drug associated with polyalkyl cyano acrylate nanoparticles. J. Pharm. Sci. 69: 199-202
8. Gabizon, A., Dagan, A., Goren, D., Barenholz, Y., Fuks, Z. (1982) Liposomes as in vivo carriers of adriamycin; reduced cardiac uptake and preserved antitumor activity in mice. Cancer Res. 42: 4734-4739
9. Gregoriadis, G., Florence, A. T. (1993) Liposomes in drug delivery, clinical, diagnostic and ophthalmic potential. Drugs 45: 15-28
10. Handjani-Vila, R. M., Ribier, A., Rondot, B., Vanerberghe, G. (1979) Dispersion of lamellar phases of non-ionic lipids in cosmetic products. Int. J. Cosmetic Sci. 1: 303-314
11. Lewis, D. A. (1984a) Red blood cells for drug delivery. Pharm. J. 233: 384-385
12. Lewis, D. A. (1984b) Therapeutic possibilities of drugs encapsulated in erythrocytes. Int. J. Pharm. 22: 137-146
13. Nagarajan, B., Chandrasekaran, B. (1985) Plant extracts echitamine and plumbagin possess antitumor activity. Abstracts of papers presented. Satellite symposium on traditional medicine as adjunct to Asian congress of Pharmacology.
14. Olson, F., Mayhew, E., Maslow, D., Rustom, Y., Szoke, F. (1982) Characterization toxicity and therapeutic efficacy of adriamycin encapsulated in liposomes. Eur. J. Clin. Oncol. 18: 167-176
15. Parimala, R., Sachdanandam, P. (1993) Effect of plumbagin on some glucose metabolizing enzymes studied in rats in experimental hepatoma. Mol. Cell. Biochem. 18: 125-159
16. Purushothaman, K. K., Mohana, K., Susan, T. (1985) Biological profile of plumbagin. Bull. Med. Ethno-Bot. Res. 6: 177
17. Rahman, A., White, G., More, N., Schein, P. S. (1985) Pharmacological, toxicological and therapeutic evaluation in mice of doxorubicin entrapped in cardiolipin liposomes. Cancer Res. 45: 796-803
18. Rogerson, A., Cummings, J., Willmott, N., Florence, A.T. (1988) The distribution of doxorubicin in mice following administration in niosomes. J. Pharm. Pharmacol. 40: 337-342
19. Santhakumari, G., Saralamma, P. G., Radhakrishnan, N. (1980) Effect of plumbagin on cell growth and mitosis, Indian J. Exp. Biol. 18: 215-218
20. Widder, K. J., Senyei, A. E., Sears, B. (1982) Experimental methods in cancer therapeutics. J. Pharm. Sci. 71: 379-387
21. Zimmerman, U., Pilwat, G., Esser, B. (1978) The effect of encapsulation in red blood cells on the distribution of methotrexate in mice. J. Clin. Chem. Biochem. 16: 135-147