An essential role for the K+-dependent Na+/Ca2+-exchanger, NCKX4, in melanocortin-4-receptor-dependent satiety

Journal of Biological Chemistry

Volumn 289, Issue 37, 2014, Pages 25445-25459

  Li, Xiao Fang ^a   Lytton, Jonathan ^a  

^a LIBIN CARDIOVASCULAR INSTITUTE OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; CELL MEMBRANES; CHEMICAL ACTIVATION; GENES; MAMMALS; NEURONS; SODIUM;

EATING DISORDERS; FEEDING BEHAVIOR; HYPERACTIVATION; HYPOTHALAMIC NEURON; PARAVENTRICULAR NUCLEUS; PHOSPHOLIPASE C; PHOSPHOLIPASE C ACTIVATIONS; PHYSIOLOGICAL ROLES;

CALCIUM;

1 [2 (4 METHOXYPHENYL) 2 [3 (4 METHOXYPHENYL)PROPOXY]ETHYL] 1H IMIDAZOLE; 1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; CALCIUM ION; GLUCOSE; HORMONE RECEPTOR BLOCKING AGENT; MELANOCORTIN 4 RECEPTOR; MELANOCORTIN 4 RECEPTOR ANTAGONIST; N ACETYL ALPHA INTERMEDIN[4-10]CYCLO[4 NORLEUCINE 5 ASPARTIC ACID 7 [3 (2 NAPHTHYL)ALANINE] 10 LYSINAMIDE]; OXYTOCIN; PHOSPHOLIPASE C; POTASSIUM DEPENDENT SODIUM CALCIUM EXCHANGE NCKX4 PROTEIN; PROTEIN C FOS; SODIUM CALCIUM EXCHANGE PROTEIN; UNCLASSIFIED DRUG; ANTIPORTER; NCKX4 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANOREXIA; ARTICLE; BODY MASS; BODY WEIGHT; CALCIUM HOMEOSTASIS; CELL ACTIVATION; CELL CULTURE; CELL MEMBRANE; CONTROLLED STUDY; DRUG ACTIVITY; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; FEEDING; FOOD INTAKE; GENE; GENE OVEREXPRESSION; GENE TARGETING; HETEROZYGOSITY; HUMAN; HUMAN CELL; HYPOPHAGIA; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; MALE; MOUSE; NCKX4 GENE; NERVE CELL; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SATIETY; SIGNAL TRANSDUCTION; WEIGHT REDUCTION; ANIMAL; BIOSYNTHESIS; CALCIUM SIGNALING; EATING DISORDERS; FEEDING BEHAVIOR; GENETICS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PSYCHOPHYSIOLOGY;

ANIMALS; ANTIPORTERS; CALCIUM SIGNALING; EATING DISORDERS; FEEDING BEHAVIOR; MICE; MICE, KNOCKOUT; NEURONS; OXYTOCIN; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; RECEPTOR, MELANOCORTIN, TYPE 4; SATIETY RESPONSE;

EID: 84907185234     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.564450     Document Type: Article

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