Transcription factor Nrf1 negatively regulates the cystine/glutamate transporter and lipid-metabolizing enzymes

Molecular and Cellular Biology

Volumn 34, Issue 20, 2014, Pages 3800-3816

  Tsujita, Tadayuki ^a,d   Peirce, V Vivian ^b   Baird, Liam ^d   Matsuyama, Yuka ^d   Takaku, Misaki ^d   Walsh, Shawn V ^c   Griffin, Julian L ^b   Uruno, Akira ^d   Yamamoto, Masayuki ^d   Hayesa, John D ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c NINEWELLS HOSPITAL   (United Kingdom)

^d TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLCHOLANTHRENE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BETA ACTIN; CD36 ANTIGEN; CRE RECOMBINASE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYSTINE; CYTOCHROME P450 1A1; FATTY ACID; GLUTAMATE TRANSPORTER; GLUTATHIONE; LACTATE DEHYDROGENASE; LIPID; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; THROMBOXANE SYNTHASE; TRANSCRIPTION FACTOR NRF1; TRANSCRIPTION FACTOR NRF2; VERY LOW DENSITY LIPOPROTEIN RECEPTOR; ACYL COENZYME A DESATURASE; AMINO ACID TRANSPORTER; LIPOPROTEIN RECEPTOR; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; NRF1 PROTEIN, MOUSE; NUCLEAR RESPIRATORY FACTOR 1; SLC7A11 PROTEIN, MOUSE; TRIACYLGLYCEROL; XCT PROTEIN, RAT;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CONTROLLED STUDY; ELECTROPHILIC STRESS; ENZYME ACTIVITY; FATTY ACID METABOLISM; GENE EXPRESSION; IMMUNOBLOTTING; KNOCKOUT MOUSE; LIPID METABOLISM; LIVER CELL; LIVER HISTOLOGY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROMOTER REGION; REAL TIME POLYMERASE CHAIN REACTION; TRANSACTIVATION; UPREGULATION; WILD TYPE; ANIMAL; C57BL MOUSE; CELL LINE; CYTOLOGY; DNA RESPONSIVE ELEMENT; FEMALE; GENE EXPRESSION REGULATION; GENETICS; LIVER; MALE; METABOLISM; PHYSIOLOGY; PROTEIN BINDING; RAT; TRANSCRIPTION INITIATION; TRANSGENIC MOUSE;

AMINO ACID TRANSPORT SYSTEM Y+; AMINO ACID TRANSPORT SYSTEMS, ACIDIC; ANIMALS; CELL LINE; CYSTINE; CYTOCHROME P-450 CYP1A1; FATTY ACID DESATURASES; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTATHIONE; HEPATOCYTES; LDL-RECEPTOR RELATED PROTEINS; LIPID METABOLISM; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NUCLEAR RESPIRATORY FACTOR 1; PROTEIN BINDING; RATS; RECEPTORS, LIPOPROTEIN; RESPONSE ELEMENTS; TRANSCRIPTIONAL ACTIVATION; TRIGLYCERIDES;

EID: 84907149982     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00110-14     Document Type: Article

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