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Volumn 155, Issue 9, 2014, Pages 3624-3637

Lgr4 gene regulates corpus luteum maturation through modulation of the WNT-mediated EGFR-ERK signaling pathway

Author keywords

[No Author keywords available]

Indexed keywords

CADHERIN; CHORIONIC GONADOTROPIN; EPIDERMAL GROWTH FACTOR RECEPTOR; GELATINASE B; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; PROGESTERONE; BETA CATENIN; EGFR PROTEIN, MOUSE; G PROTEIN COUPLED RECEPTOR; LGR4 PROTEIN, MOUSE; WNT PROTEIN;

EID: 84907059495     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2013-2183     Document Type: Article
Times cited : (31)

References (56)
  • 1
    • 0014452164 scopus 로고
    • The luteo-placental shift, the guardian of pre-natal life
    • Csapo A. The luteo-placental shift, the guardian of pre-natal life. Postgrad Med J. 1969;45:57-64.
    • (1969) Postgrad Med J. , vol.45 , pp. 57-64
    • Csapo, A.1
  • 3
    • 0036200191 scopus 로고    scopus 로고
    • Ovulation: New dimensions and new regulators of the inflammatory-like response
    • Richards JS, Russell DL, Ochsner S, Espey LL. Ovulation: new dimensions and new regulators of the inflammatory-like response. Annu Rev Physiol. 2002;64:69-92.
    • (2002) Annu Rev Physiol. , vol.64 , pp. 69-92
    • Richards, J.S.1    Russell, D.L.2    Ochsner, S.3    Espey, L.L.4
  • 4
    • 0036150876 scopus 로고    scopus 로고
    • Intact follicular maturation and defective luteal function in mice deficient for cyclin-de-pendent kinase-4
    • Moons DS, Jirawatnotai S, Tsutsui T, et al. Intact follicular maturation and defective luteal function in mice deficient for cyclin-de-pendent kinase-4. Endocrinology. 2002;143:647-654.
    • (2002) Endocrinology. , vol.143 , pp. 647-654
    • Moons, D.S.1    Jirawatnotai, S.2    Tsutsui, T.3
  • 6
    • 61449101551 scopus 로고    scopus 로고
    • Epidermal growth factor-like growth factors in the follicular fluid: Role in oocyte development and maturation
    • Hsieh M, Zamah AM, Conti M. Epidermal growth factor-like growth factors in the follicular fluid: role in oocyte development and maturation. Semin Reprod Med. 2009;27:52-61.
    • (2009) Semin Reprod Med. , vol.27 , pp. 52-61
    • Hsieh, M.1    Zamah, A.M.2    Conti, M.3
  • 8
    • 0942301323 scopus 로고    scopus 로고
    • EGF-like growth factors as mediators of LH action in the ovulatory follicle
    • Park JY, Su YQ, Ariga M, Law E, Jin SL, Conti M. EGF-like growth factors as mediators of LH action in the ovulatory follicle. Science. 2004;303:682-684.
    • (2004) Science. , vol.303 , pp. 682-684
    • Park, J.Y.1    Su, Y.Q.2    Ariga, M.3    Law, E.4    Jin, S.L.5    Conti, M.6
  • 9
    • 41649091053 scopus 로고    scopus 로고
    • Luteinizing hormone signaling in preovulatory follicles involves early activation of the epidermal growth factor receptor pathway
    • Panigone S, Hsieh M, Fu M, Persani L, Conti M. Luteinizing hormone signaling in preovulatory follicles involves early activation of the epidermal growth factor receptor pathway. Mol Endocrinol. 2008;22:924-936.
    • (2008) Mol Endocrinol. , vol.22 , pp. 924-936
    • Panigone, S.1    Hsieh, M.2    Fu, M.3    Persani, L.4    Conti, M.5
  • 10
    • 0342264613 scopus 로고    scopus 로고
    • Developmental regulation of effect of epidermal growth factor on porcine oocyte-cumulus cell complexes: Nuclear maturation, expansion, and F-actin remodeling
    • Procházka R, Srsen V, Nagyová E, Miyano T, Flechon JE. Developmental regulation of effect of epidermal growth factor on porcine oocyte-cumulus cell complexes: nuclear maturation, expansion, and F-actin remodeling. Mol Reprod Dev. 2000;56:63-73.
    • (2000) Mol Reprod Dev. , vol.56 , pp. 63-73
    • Procházka, R.1    Srsen, V.2    Nagyová, E.3    Miyano, T.4    Flechon, J.E.5
  • 11
    • 66149129235 scopus 로고    scopus 로고
    • MAPK3/1 (ERK1/2) in ovarian granulosa cells are essential for female fertility
    • Fan HY, Liu Z, Shimada M, et al. MAPK3/1 (ERK1/2) in ovarian granulosa cells are essential for female fertility. Science. 2009;324: 938-941.
    • (2009) Science. , vol.324 , pp. 938-941
    • Fan, H.Y.1    Liu, Z.2    Shimada, M.3
  • 12
    • 79959742666 scopus 로고    scopus 로고
    • Genetic dissection of epidermal growth factor receptor signaling during luteinizing hormone-induced oocyte maturation
    • Hsieh M, Thao K, Conti M. Genetic dissection of epidermal growth factor receptor signaling during luteinizing hormone-induced oocyte maturation. PloS One. 2011;6:e21574.
    • (2011) PloS One. , vol.6 , pp. e21574
    • Hsieh, M.1    Thao, K.2    Conti, M.3
  • 13
    • 33745714456 scopus 로고    scopus 로고
    • ADAMs as mediators of EGF receptor transactivation by G protein-coupled receptors
    • Ohtsu H, Dempsey PJ, Eguchi S. ADAMs as mediators of EGF receptor transactivation by G protein-coupled receptors. Am J Physiol Cell Physiol. 2006;291:C1-C10.
    • (2006) Am J Physiol Cell Physiol. , vol.291 , pp. C1-C10
    • Ohtsu, H.1    Dempsey, P.J.2    Eguchi, S.3
  • 14
    • 40449138006 scopus 로고    scopus 로고
    • Autocrine WNT signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivation
    • Schlange T, Matsuda Y, Lienhard S, Huber A, Hynes NE. Autocrine WNT signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivation. Breast Cancer Res. 2007;9:R63.
    • (2007) Breast Cancer Res. , vol.9 , pp. R63
    • Schlange, T.1    Matsuda, Y.2    Lienhard, S.3    Huber, A.4    Hynes, N.E.5
  • 15
    • 0033599039 scopus 로고    scopus 로고
    • EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF
    • Prenzel N, Zwick E, Daub H, et al. EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. Nature. 1999;402:884-888.
    • (1999) Nature. , vol.402 , pp. 884-888
    • Prenzel, N.1    Zwick, E.2    Daub, H.3
  • 16
    • 0033521967 scopus 로고    scopus 로고
    • Female development in mammals is regulated by Wnt-4 signalling
    • Vainio S, Heikkilä M, Kispert A, Chin N, McMahon AP. Female development in mammals is regulated by Wnt-4 signalling. Nature. 1999;397:405-409.
    • (1999) Nature. , vol.397 , pp. 405-409
    • Vainio, S.1    Heikkilä, M.2    Kispert, A.3    Chin, N.4    McMahon, A.P.5
  • 17
    • 77954989759 scopus 로고    scopus 로고
    • WNT4 is required for normal ovarian follicle development and female fertility
    • Boyer A, Lapointe E, Zheng X, et al. WNT4 is required for normal ovarian follicle development and female fertility. FASEB J. 2010; 24:3010-3025.
    • (2010) FASEB J. , vol.24 , pp. 3010-3025
    • Boyer, A.1    Lapointe, E.2    Zheng, X.3
  • 18
    • 28144449280 scopus 로고    scopus 로고
    • -/-) are infertile and exhibit impaired corpora lutea formation and function
    • -/-) are infertile and exhibit impaired corpora lutea formation and function. Biol Reprod. 2005;73:1135-1146.
    • (2005) Biol Reprod. , vol.73 , pp. 1135-1146
    • Hsieh, M.1    Boerboom, D.2    Shimada, M.3
  • 19
    • 84880799266 scopus 로고    scopus 로고
    • Lhcgr expression in granulosa cells: Roles for PKA-phosphorylated β-catenin TCF3 and FOXO1
    • Law NC, Weck J, Kyriss B, Nilson JH, Hunzicker-Dunn M. Lhcgr expression in granulosa cells: roles for PKA-phosphorylated β-catenin, TCF3, and FOXO1. Mol Endocrinol. 2013;27:1295-1310.
    • (2013) Mol Endocrinol. , vol.27 , pp. 1295-1310
    • Law, N.C.1    Weck, J.2    Kyriss, B.3    Nilson, J.H.4    Hunzicker-Dunn, M.5
  • 20
    • 80051926611 scopus 로고    scopus 로고
    • Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling
    • de Lau W, Barker N, Low TY, et al. Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling. Nature. 2011;476: 293-297.
    • (2011) Nature. , vol.476 , pp. 293-297
    • De Lau, W.1    Barker, N.2    Low, T.Y.3
  • 21
    • 79960990066 scopus 로고    scopus 로고
    • R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling
    • Carmon KS, Gong X, Lin Q, Thomas A, Liu Q. R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling. Proc Natl Acad Sci USA. 2011;108: 11452-11457.
    • (2011) Proc Natl Acad Sci USA. , vol.108 , pp. 11452-11457
    • Carmon, K.S.1    Gong, X.2    Lin, Q.3    Thomas, A.4    Liu, Q.5
  • 22
    • 84858332552 scopus 로고    scopus 로고
    • An evolutionary comparison of leucine-rich repeat containing G protein-coupled receptors reveals a novel LGR subtype
    • Van Hiel MB, Vandersmissen HP, Van Loy T, Vanden Broeck J. An evolutionary comparison of leucine-rich repeat containing G protein-coupled receptors reveals a novel LGR subtype. Peptides. 2012; 34:193-200.
    • (2012) Peptides. , vol.34 , pp. 193-200
    • Van Hiel, M.B.1    Vandersmissen, H.P.2    Van Loy, T.3    Vanden Broeck, J.4
  • 23
    • 0000437998 scopus 로고    scopus 로고
    • Characterization of two LGR genes homologous to gonadotropin and thyrotropin receptors with extracellular leucine-rich repeats and a G protein-coupled, seven-transmembrane region
    • Hsu SY, Liang SG, Hsueh AJ. Characterization of two LGR genes homologous to gonadotropin and thyrotropin receptors with extracellular leucine-rich repeats and a G protein-coupled, seven-transmembrane region. Mol Endocrinol. 1998;12:1830-1845.
    • (1998) Mol Endocrinol. , vol.12 , pp. 1830-1845
    • Hsu, S.Y.1    Liang, S.G.2    Hsueh, A.J.3
  • 24
    • 4544238417 scopus 로고    scopus 로고
    • Leucine-rich repeat-containing G protein-coupled receptor 4 null mice exhibit intrauterine growth retardation associated with embryonic and perinatal lethality
    • Mazerbourg S, Bouley DM, Sudo S, et al. Leucine-rich repeat-containing, G protein-coupled receptor 4 null mice exhibit intrauterine growth retardation associated with embryonic and perinatal lethality. Mol Endocrinol. 2004;18:2241-2254.
    • (2004) Mol Endocrinol. , vol.18 , pp. 2241-2254
    • Mazerbourg, S.1    Bouley, D.M.2    Sudo, S.3
  • 25
    • 69049090918 scopus 로고    scopus 로고
    • Regulation of bone formation and remodeling by G-protein-coupled receptor 48
    • Luo J, Zhou W, Zhou X, et al. Regulation of bone formation and remodeling by G-protein-coupled receptor 48. Development. 2009; 136:2747-2756.
    • (2009) Development. , vol.136 , pp. 2747-2756
    • Luo, J.1    Zhou, W.2    Zhou, X.3
  • 26
    • 61449197690 scopus 로고    scopus 로고
    • Inactivation of G-protein-coupled receptor 48 (Gpr48/Lgr4) impairs definitive erythropoiesis atmidg-estation through down-regulation of the ATF4 signaling pathway
    • Song H, Luo J, Luo W, et al. Inactivation of G-protein-coupled receptor 48 (Gpr48/Lgr4) impairs definitive erythropoiesis atmidg-estation through down-regulation of the ATF4 signaling pathway. J Biol Chem. 2008;283:36687-36697.
    • (2008) J Biol Chem. , vol.283 , pp. 36687-36697
    • Song, H.1    Luo, J.2    Luo, W.3
  • 27
    • 84863158405 scopus 로고    scopus 로고
    • GPR48 increases mineralocorticoid receptor gene expression
    • Wang J, Li X, Ke Y, et al. GPR48 increases mineralocorticoid receptor gene expression. J Am Soc Nephrol. 2012;23:281-293.
    • (2012) J Am Soc Nephrol. , vol.23 , pp. 281-293
    • Wang, J.1    Li, X.2    Ke, Y.3
  • 28
    • 84876010537 scopus 로고    scopus 로고
    • Lgr4 gene deficiency increases susceptibility and severity of dextran sodium sulfate-induced inflammatory bowel disease in mice
    • discussion 8804
    • Liu S, Qian Y, Li L, et al. Lgr4 gene deficiency increases susceptibility and severity of dextran sodium sulfate-induced inflammatory bowel disease in mice. J Biol Chem. 2013;288:8794-8803; discussion 8804.
    • (2013) J Biol Chem. , vol.288 , pp. 8794-8803
    • Liu, S.1    Qian, Y.2    Li, L.3
  • 30
    • 84890448010 scopus 로고    scopus 로고
    • LGR4 expressed in uterine epithelium is necessary for uterine gland development and contributes to decidualization in mice
    • Sone M, Oyama K, Mohri Y, Hayashi R, Clevers H, Nishimori K. LGR4 expressed in uterine epithelium is necessary for uterine gland development and contributes to decidualization in mice. FASEB J. 2013;27:4917-4928.
    • (2013) FASEB J. , vol.27 , pp. 4917-4928
    • Sone, M.1    Oyama, K.2    Mohri, Y.3    Hayashi, R.4    Clevers, H.5    Nishimori, K.6
  • 31
    • 43149099246 scopus 로고    scopus 로고
    • Deletion of G protein-coupled receptor 48 leads to ocular anterior segment dysgenesis (ASD) through down-regulation of Pitx2
    • Weng J, Luo J, Cheng X, et al. Deletion of G protein-coupled receptor 48 leads to ocular anterior segment dysgenesis (ASD) through down-regulation of Pitx2. Proc Natl Acad Sci USA. 2008;105: 6081-6086.
    • (2008) Proc Natl Acad Sci USA. , vol.105 , pp. 6081-6086
    • Weng, J.1    Luo, J.2    Cheng, X.3
  • 33
    • 77950404648 scopus 로고    scopus 로고
    • RUNX2 transcription factor regulates gene expression in luteinizing granulosa cells of rat ovaries
    • Park ES, Lind AK, Dahm-Kähler P, et al. RUNX2 transcription factor regulates gene expression in luteinizing granulosa cells of rat ovaries. Mol Endocrinol. 2010;24:846-858.
    • (2010) Mol Endocrinol. , vol.24 , pp. 846-858
    • Park, E.S.1    Lind, A.K.2    Dahm-Kähler, P.3
  • 34
    • 33847268280 scopus 로고    scopus 로고
    • Wnt signaling induces matrix metalloproteinase expression and regulates T cell transmigration
    • Wu B, Crampton SP, Hughes CC. Wnt signaling induces matrix metalloproteinase expression and regulates T cell transmigration. Immunity. 2007;26:227-239.
    • (2007) Immunity. , vol.26 , pp. 227-239
    • Wu, B.1    Crampton, S.P.2    Hughes, C.C.3
  • 35
    • 73649092120 scopus 로고    scopus 로고
    • G protein-coupled receptor 48 upregu-lates estrogen receptor alpha expression via cAMP/PKA signaling in the male reproductive tract
    • Li XY, Lu Y, Sun HY, et al. G protein-coupled receptor 48 upregu-lates estrogen receptor alpha expression via cAMP/PKA signaling in the male reproductive tract. Development. 2010;137:151-157.
    • (2010) Development. , vol.137 , pp. 151-157
    • Li, X.Y.1    Lu, Y.2    Sun, H.Y.3
  • 37
    • 79951711601 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding proteins (C/EBP)-a and-/3 are essential for ovulation, luteinization, and the expression of key target genes
    • Fan HY, Liu Z, Johnson PF, Richards JS. CCAAT/enhancer-binding proteins (C/EBP)-a and-/3 are essential for ovulation, luteinization, and the expression of key target genes. Molecular endocrinology. 2011;25:253-268.
    • (2011) Molecular Endocrinology. , vol.25 , pp. 253-268
    • Fan, H.Y.1    Liu, Z.2    Johnson, P.F.3    Richards, J.S.4
  • 38
    • 27144459854 scopus 로고    scopus 로고
    • Gene expression and im-munolocalization of heparin-binding epidermal growth factor-like growth factor and human epidermal growth factor receptors in human corpus luteum
    • Akayama Y, Takekida S, Ohara N, et al. Gene expression and im-munolocalization of heparin-binding epidermal growth factor-like growth factor and human epidermal growth factor receptors in human corpus luteum. Hum Reprod. 2005;20:2708-2714.
    • (2005) Hum Reprod. , vol.20 , pp. 2708-2714
    • Akayama, Y.1    Takekida, S.2    Ohara, N.3
  • 39
    • 34547483968 scopus 로고    scopus 로고
    • Follicle-stimulating hormone induces multiple signaling cascades: Evidence that activation of Rous sarcoma oncogene RAS and the epidermal growth factor receptor are critical for granulosa cell differentiation
    • Wayne CM, Fan HY, Cheng X, Richards JS. Follicle-stimulating hormone induces multiple signaling cascades: evidence that activation of Rous sarcoma oncogene, RAS, and the epidermal growth factor receptor are critical for granulosa cell differentiation. Mol Endocrinol. 2007;21:1940-1957.
    • (2007) Mol Endocrinol. , vol.21 , pp. 1940-1957
    • Wayne, C.M.1    Fan, H.Y.2    Cheng, X.3    Richards, J.S.4
  • 40
    • 73249124003 scopus 로고    scopus 로고
    • WNT signaling in ovarian follicle biology and tumorigenesis
    • Boyer A, Goff AK, Boerboom D. WNT signaling in ovarian follicle biology and tumorigenesis. Trends Endocrinol Metab. 2010; 21:25-32.
    • (2010) Trends Endocrinol Metab. , vol.21 , pp. 25-32
    • Boyer, A.1    Goff, A.K.2    Boerboom, D.3
  • 41
    • 70649105588 scopus 로고    scopus 로고
    • Integration of the beta-catenin-dependent Wnt pathway with integrin signaling through the adaptor molecule Grb2
    • Crampton SP, Wu B, Park EJ, et al. Integration of the beta-catenin-dependent Wnt pathway with integrin signaling through the adaptor molecule Grb2. PloS One. 2009;4:e7841.
    • (2009) PloS One. , vol.4 , pp. e7841
    • Crampton, S.P.1    Wu, B.2    Park, E.J.3
  • 42
    • 79957666660 scopus 로고    scopus 로고
    • GPCR/EGFR cross talk is conserved in gonadal and adrenal steroidogenesis but is uniquely regulated by matrix metalloproteinases 2 and 9 in the ovary
    • Carbajal L, Biswas A, Niswander LM, Prizant H, Hammes SR. GPCR/EGFR cross talk is conserved in gonadal and adrenal steroidogenesis but is uniquely regulated by matrix metalloproteinases 2 and 9 in the ovary. Mol Endocrinol. 2011;25:1055-1065.
    • (2011) Mol Endocrinol. , vol.25 , pp. 1055-1065
    • Carbajal, L.1    Biswas, A.2    Niswander, L.M.3    Prizant, H.4    Hammes, S.R.5
  • 43
    • 0344443646 scopus 로고    scopus 로고
    • Matrix metalloproteinases 2 and 9 mediate epidermal growth factor receptor transactivation by gonadotropin-releasing hormone
    • Roelle S, Grosse R, Aigner A, Krell HW, Czubayko F, Gudermann T. Matrix metalloproteinases 2 and 9 mediate epidermal growth factor receptor transactivation by gonadotropin-releasing hormone. J Biol Chem. 2003;278:47307-47318.
    • (2003) J Biol Chem. , vol.278 , pp. 47307-47318
    • Roelle, S.1    Grosse, R.2    Aigner, A.3    Krell, H.W.4    Czubayko, F.5    Gudermann, T.6
  • 44
    • 78650181939 scopus 로고    scopus 로고
    • Reduced fertility with impairment of early-stage embryos observed in mice lacking Lgr4 in epithelial tissues
    • Mohri Y, Umezu T, Hidema S, et al. Reduced fertility with impairment of early-stage embryos observed in mice lacking Lgr4 in epithelial tissues. Fertil Steril. 2010;94:2878-2881.
    • (2010) Fertil Steril. , vol.94 , pp. 2878-2881
    • Mohri, Y.1    Umezu, T.2    Hidema, S.3
  • 45
    • 80053560465 scopus 로고    scopus 로고
    • LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signalling
    • Glinka A, Dolde C, Kirsch N, et al. LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signalling. EMBO Rep. 2011;12:1055-1061.
    • (2011) EMBO Rep. , vol.12 , pp. 1055-1061
    • Glinka, A.1    Dolde, C.2    Kirsch, N.3
  • 47
    • 77953837003 scopus 로고    scopus 로고
    • WNT2 regulates DNA synthesis in mouse granulosa cells through beta-catenin
    • Wang HX, Li TY, Kidder GM. WNT2 regulates DNA synthesis in mouse granulosa cells through beta-catenin. Biol Reprod. 2010;82: 865-875.
    • (2010) Biol Reprod. , vol.82 , pp. 865-875
    • Wang, H.X.1    Li, T.Y.2    Kidder, G.M.3
  • 48
    • 84886918478 scopus 로고    scopus 로고
    • The canonical WNT2 pathway and FSH interact to regulate gap junction assembly in mouse granulosa cells
    • Wang HX, Gillio-Meina C, Chen S, et al. The canonical WNT2 pathway and FSH interact to regulate gap junction assembly in mouse granulosa cells. Biol Reprod. 2013;89:39.
    • (2013) Biol Reprod. , vol.89 , pp. 39
    • Wang, H.X.1    Gillio-Meina, C.2    Chen, S.3
  • 49
    • 77954983457 scopus 로고    scopus 로고
    • Beta-catenin (CTNNB1) promotes preovulatory follicular development but represses LH-mediated ovulation and luteinization
    • Fan HY, O'Connor A, Shitanaka M, Shimada M, Liu Z, Richards JS. Beta-catenin (CTNNB1) promotes preovulatory follicular development but represses LH-mediated ovulation and luteinization. Mol Endocrinol. 2010;24:1529-1542.
    • (2010) Mol Endocrinol. , vol.24 , pp. 1529-1542
    • Fan, H.Y.1    O'Connor, A.2    Shitanaka, M.3    Shimada, M.4    Liu, Z.5    Richards, J.S.6
  • 50
    • 66149125539 scopus 로고    scopus 로고
    • Conditional deletionofbeta-catenin mediated by Amhr2crein mice causes female infertility
    • Hernandez Gifford JA, Hunzicker-Dunn ME, Nilson JH. Conditional deletionofbeta-catenin mediated by Amhr2crein mice causes female infertility. Biol Reprod. 2009;80:1282-1292.
    • (2009) Biol Reprod. , vol.80 , pp. 1282-1292
    • Hernandez Gifford, J.A.1    Hunzicker-Dunn, M.E.2    Nilson, J.H.3
  • 52
    • 33644520252 scopus 로고    scopus 로고
    • Dominant-stable beta-catenin expression causes cell fate alterations and Wnt signaling antagonist expression in a murine granulosa cell tumor model
    • Boerboom D, White LD, Dalle S, Courty J, Richards JS. Dominant-stable beta-catenin expression causes cell fate alterations and Wnt signaling antagonist expression in a murine granulosa cell tumor model. Cancer research. 2006;66:1964-1973.
    • (2006) Cancer Research. , vol.66 , pp. 1964-1973
    • Boerboom, D.1    White, L.D.2    Dalle, S.3    Courty, J.4    Richards, J.S.5
  • 53
    • 84896735708 scopus 로고    scopus 로고
    • Signaling cross-talk in the resistance to HER family receptor targeted therapy
    • Yamaguchi H, Chang SS, Hsu JL, Hung MC. Signaling cross-talk in the resistance to HER family receptor targeted therapy. Oncogene. 2013;33:1073-1081.
    • (2013) Oncogene. , vol.33 , pp. 1073-1081
    • Yamaguchi, H.1    Chang, S.S.2    Hsu, J.L.3    Hung, M.C.4
  • 54
    • 84876581873 scopus 로고    scopus 로고
    • In vitro effects of a small-molecule antagonist of the tcf/ss-catenin complex on endometrial and endometri-otic cells of patients with endometriosis
    • Matsuzaki S, Darcha C. In vitro effects of a small-molecule antagonist of the tcf/ss-catenin complex on endometrial and endometri-otic cells of patients with endometriosis. PloS One. 2013;8:e61690.
    • (2013) PloS One. , vol.8 , pp. e61690
    • Matsuzaki, S.1    Darcha, C.2
  • 55
    • 79955975393 scopus 로고    scopus 로고
    • Matrix metalloproteinase (MMP)-9 induced by Wnt signaling increases the proliferation and migration of embryonic neural stem cells at low O2 levels
    • Ingraham CA, Park GC, Makarenkova HP, Crossin KL. Matrix metalloproteinase (MMP)-9 induced by Wnt signaling increases the proliferation and migration of embryonic neural stem cells at low O2 levels. J Biol Chem. 2011;286:17649-17657.
    • (2011) J Biol Chem. , vol.286 , pp. 17649-17657
    • Ingraham, C.A.1    Park, G.C.2    Makarenkova, H.P.3    Crossin, K.L.4
  • 56
    • 0033818704 scopus 로고    scopus 로고
    • Gelatinase B deficiency impairs reproduction
    • Dubois B, Arnold B, Opdenakker G. Gelatinase B deficiency impairs reproduction. J Clin Invest. 2000;106:627-628.
    • (2000) J Clin Invest. , vol.106 , pp. 627-628
    • Dubois, B.1    Arnold, B.2    Opdenakker, G.3


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