MAPK3/1 (ERK1/2) in ovarian granulosa cells are essential for female fertility

Science

Volumn 324, Issue 5929, 2009, Pages 938-941

  Fan, Heng Yu ^a   Liu, Zhilin ^a   Shimada, Masayuki ^b   Sterneck, Esta ^c   Johnson, Peter F ^c   Hedrick, Stephen M ^d   Richards, Joanne S ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b HIROSHIMA UNIVERSITY   (Japan)

^c NATIONAL CANCER INSTITUTE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; LUTEINIZING HORMONE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3;

CYTOLOGY; FERTILITY; HORMONE; MAMMAL; REPRODUCTIVE CYCLE; REPRODUCTIVE SUCCESS; RODENT;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CEBPB GENE; CHEMICAL ANALYSIS; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; FEMALE FERTILITY; GENE; GENE DISRUPTION; GRANULOSA CELL; IN VIVO STUDY; LUTEINIZATION; MEIOSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; OVULATION; PRIORITY JOURNAL; ANIMAL; C57BL MOUSE; ENZYMOLOGY; FERTILITY; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; OVARY FOLLICLE; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

MAMMALIA;

ANIMALS; CCAAT-ENHANCER-BINDING PROTEIN-BETA; ENZYME ACTIVATION; FEMALE; FERTILITY; GENE EXPRESSION PROFILING; GRANULOSA CELLS; LUTEINIZING HORMONE; MAP KINASE SIGNALING SYSTEM; MEIOSIS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; OOCYTES; OVARIAN FOLLICLE; OVULATION; PHOSPHORYLATION;

EID: 66149129235     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1171396     Document Type: Article

References (20)

1. M. Hunzicker-Dunn, E. T. Maizels, Cell. Signal. 18, 1351 (2006).
2. M. M. Matzuk, K. H. Burns, M. M. Viveiros, J. J. Eppig, Science 296, 2178 (2002).
3. J. Y. Park et al., Science 303, 682 (2004).
4. M. Hsieh et al., Mol. Cell. Biol. 27, 1914 (2007).
5. M. Shimada, I. Hernandez-Gonzalez, I. Gonzalez-Robayna, J. S. Richards, Mol. Endocrinol. 20, 1352 (2006).
6. Y. Q. Su, K. Wigglesworth, F. L. Pendola, M. J. O'Brien, J. J. Eppig, Endocrinology 143, 2221 (2002).
7. Z. Chen et al., Chem. Rev. 101, 2449 (2001).
8. G. Pages et al., Science 286, 1374 (1999).
9. M. Aouadi, B. Binetruy, L. Caron, Y. Le Marchand-Brustel, F. Bost, Biochimie 88, 1091 (2006).
10. A. M. Fischer, C. D. Katayama, G. Pages, J. Pouyssegur, S. M. Hedrick, Immunity23, 431 (2005).
11. H. Y. Fan et al., Development 135, 2127 (2008).
12. S. Panigone, M. Hsieh, M. Fu, L. Persani, M. Conti, Mol. Endocrinol. 22, 924 (2008).
13. E. Gershon, A. Hourvitz, S. Reikhav, E. Maman, N. Dekel, FASEB J. 21, 1893 (2007).
14. J. S. Richards, Endocrinology 142, 2184 (2001).
15. E. Sterneck, L. Tessarollo, P. F. Johnson, Genes Dev. 11, 2153 (1997).
16. M. Buck, V. Poli, P. vander Geer, M. Chojkier, T. Hunter, Mol. Cell 4, 1087 (1999).
17. E. Sterneck, S. Zhu, A. Ramirez, J. L. Jorcano, R. C. Smart, Oncogene 25, 1272 (2006).
18. S. Sela-Abramovich, E. Chorev, D. Galiani, N. Dekel, Endocrinology 146, 1236 (2005).
19. E. T. Maizels, J. Cottom, J. C. Jones, M. Hunzicker-Dunn, Endocrinology 139, 3353 (1998).
20. -/- mice and adenoviral vector of C/EBPβ, respectively. This work was supported by NIH grants NIH-HD16229, NIH-HD07495, Project II (J.S.R.), Grant-in-Aid for Scientific Research No. 18688016 from the Japan Society for the Promotion of Science (M.S.), Intramural Research Program of NIH, National Cancer Institute, Center for Cancer Research (P.F.J. and E.S.), and NIH Postdoctoral Training Grant NIH-HD07165 (H.-Y.F.). The Gene Expression Omnibus accession number for microarray data is GSE15135.