Lgr4 gene deficiency increases susceptibility and severity of dextran sodium sulfate-induced inflammatory bowel disease in mice

Journal of Biological Chemistry

Volumn 288, Issue 13, 2013, Pages 8794-8803

  Liu, Shijie ^a   Qian, Yu ^a   Li, Liang ^a   Wei, Gaigai ^a   Guan, Yuting ^a   Pan, Hongjie ^a   Guan, Xin ^a   Zhang, Long ^a   Lu, Xiaoling ^b   Zhao, Yongxiang ^b   Liu, Mingyao ^a,c   Li, Dali ^a  

^a EAST CHINA NORMAL UNIVERSITY   (China)

^b GUANGXI MEDICAL UNIVERSITY   (China)

^c TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATENIN SIGNALING; DEXTRAN SULFATE SODIUM; INFLAMMATORY BOWEL DISEASE; INTESTINAL EPITHELIAL CELLS; INTESTINAL INFLAMMATION; MOLECULAR MECHANISM; RECOVERY PERIODS; REGENERATION PROCESS;

ACTIVATION ANALYSIS; CELL DEATH; CELL PROLIFERATION; MAMMALS; PATHOLOGY; PHYSIOLOGY; STEM CELLS;

CELL SIGNALING;

BETA CATENIN; BETA DEFENSIN 5; DEXTRAN SULFATE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MATRILYSIN; MESSENGER RNA; MICROORGANISM PROTEIN; PROTEIN CRS1C; PROTEIN CRS4C; PROTEIN LYZ2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; WNT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL POPULATION; CELL PROLIFERATION; COLITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; DOWN REGULATION; ENTERITIS; GENE; GENE DELETION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE IDENTIFICATION; GENETIC SUSCEPTIBILITY; INTRACELLULAR SIGNALING; LGR4 GENE; MOLECULAR PATHOLOGY; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PANETH CELL; PRIORITY JOURNAL; SURVIVAL RATE;

ANIMALS; BETA CATENIN; BONE MARROW TRANSPLANTATION; COLITIS; DEXTRANS; DRUG DISCOVERY; GENE DELETION; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; HOMEOSTASIS; INFLAMMATORY BOWEL DISEASES; MICE; MICE, TRANSGENIC; RECEPTORS, G-PROTEIN-COUPLED; REGENERATION; SIGNAL TRANSDUCTION; STEM CELLS; SULFATES; THROMBOSPONDINS; WNT PROTEINS;

ANIMALIA; MUS;

EID: 84876010537     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.436204     Document Type: Article

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