The role of gonadotropins in the follicular phase

Annals of the New York Academy of Sciences

Volumn 1205, Issue , 2010, Pages 5-11

  Messinis, Ioannis E ^a   Messini, Christina I ^a   Dafopoulos, Konstantinos ^a  

^a UNIVERSITY OF THESSALY   (Greece)

Author keywords

follicle; follicular phase; FSH; LH

Indexed keywords

ANDROGEN; CETRORELIX; CLOMIFENE CITRATE; ESTROGEN; FOLLITROPIN; GONADORELIN AGONIST; GONADORELIN ANTAGONIST; GONADOTROPIN; LUTEINIZING HORMONE;

ANDROGEN SYNTHESIS; CONFERENCE PAPER; ESTROGEN SYNTHESIS; FERTILIZATION IN VITRO; FOLLICULAR PHASE; HUMAN; LUTEINIZING HORMONE RELEASE; OVARY FOLLICLE DEVELOPMENT; OVARY FOLLICLE MATURATION; OVULATION INDUCTION; SINGLE DRUG DOSE; STEROIDOGENESIS; BIOLOGICAL MODEL; CELL SIZE; DRUG EFFECTS; FEMALE; GROWTH, DEVELOPMENT AND AGING; METABOLISM; OVARY FOLLICLE; PHYSIOLOGY;

CELL SIZE; FEMALE; FOLLICULAR PHASE; GONADOTROPINS; HUMANS; LUTEINIZING HORMONE; MODELS, BIOLOGICAL; OVARIAN FOLLICLE;

EID: 77957078801     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2010.05660.x     Document Type: Conference Paper

References (47)

1. Gougeon, A. 1986. Dynamics of follicular growth in the human: a model from preliminary results. Hum. Reprod. 1: 81-87.
2. Messinis, I.E. 2008. Mechanisms of follicular development: the role of gonadotropins. In Infertility and Assisted Reproduction. B. Rizk, J. Garcia-Velasco, H. Sallam & A. Makrigiannakis, Eds.: 10-24. Cambridge University Press. New York.
3. McGee, E., N. Spears, S.Minami, et al. 1997. Preantral ovarian follicles in serum-free culture: suppression of apoptosis after activation of the cyclic guanosine 3,5-monophosphate pathway and stimulation of growth and differentiation by follicle-stimulating hormone. Endocrinology 138: 2417-2424.
4. Visser, J.A.&A.P.Themmen. 2005.Anti-Mullerian hormone and folliculogenesis. Mol. Cell. Endocrinol. 234: 81-86.
5. Carlsson, I.B., J.E. Scott, J.A. Visser, et al. 2006. Anti- Mullerian hormone inhibits initiation of growth of human primordial ovarian follicles in vitro.Hum. Reprod. 21: 2223-2227.
6. Erickson, G.F. & S. Shimasaki. 2001. The physiology of folliculogenesis: the role of novel growth factors. Fertil. Steril. 76: 943-949.
7. Erickson, G.F. & S. Shimasaki. 2000. The role of the oocyte in folliculogenesis. Trends Endocrinol. Metab. 11: 193-198.
8. Mais, V., N.S. Cetel, K.N. Muse, et al. 1987. Hormonal dynamics during luteal-follicular transition. J. Clin. Endocrinol. Metab. 64: 1109-1114.
9. Messinis, I.E., D. Koutsoyiannis, S. Milingos, et al. 1993. Changes in pituitary response to GnRH during the lutealfollicular transition of the humanmenstrual cycle. Clin. Endocrinol. (Oxf.). 38: 159-163.
10. McGee, E.A. & A.J. Hsueh. 2000. Initial and cyclic recruitment of ovarian follicles. Endocr. Rev. 21: 200-214.
11. Brown, J.B., J.H. Evans, F.D. Adey & H.P. Taft. 1969. Factors involved in the induction of fertile ovulation with human gonadotrophins. J.Obstet.Gynaecol. Br. Commonw. 76: 289-307.
12. MacNatty, K.P.,W.M.Hunter, A.S.MacNeilly &R.S. Sawers. 1975. Changes in the concentration of pituitary and steroid hormones in the follicular fluid of human graafian follicles throughout the menstrual cycle. J. Endocrinol. 64: 555-571.
13. Hillier, S.G., P.F. Whitelaw & C.D. Smyth. 1994. Follicular oestrogen synthesis: the two-cell, two-gonadotrophin model revisited. Mol. Cell. Endocrinol. 100: 51-54.
14. Whitelaw, P.F., C.D. Smyth, C.M. Howles & S.G. Hillier. 1992. Cell-specific expression of aromatase and LH receptor mRNAs in rat ovary. J Mol. Endocrinol. 9: 309-312.
15. Hillier, S.G. 2001. Gonadotropic control of ovarian follicular growth and development.Mol. Cell. Endocrinol. 179: 39-46.
16. Spicer, L.J. 2004. Proteolytic degradation of insulin-like growth factor binding proteins by ovarian follicles: a control mechanism for selection of dominant follicles. Biol. Reprod. 70: 1223-1230.
17. Magoffin, D.A. & S.R. Weitsman. 1994. Insulin-like growth factor-I regulation of luteinizing hormone (LH) receptor messenger ribonucleic acid expression and LH-stimulated signal transduction in rat ovarian theca-interstitial cells. Biol. Reprod. 51: 766-775.
18. Billig, H., I. Furuta & A.J. Hsueh. 1993. Estrogens inhibit and androgens enhance ovarian granulosa cell apoptosis. Endocrinology. 133: 2204-2212.
19. Tetsuka, M.&S.G.Hillier. 1996. Androgen receptor gene expression in rat granulosa cells: the role of follicle-stimulating hormone and steroid hormones. Endocrinology 137: 4392-4397.
20. Adashi, E.Y.&A.J. Hsueh. 1982. Estrogens augment the stimulation of ovarian aromatase activity by follicle-stimulating hormone in cultured rat granulosa cells. J. Biol. Chem. 257: 6077-6083.
21. Karamouti, M., P. Kollia, A. Kallitsaris, et al. 2008. Growth hormone, insulin-like growth factor I, and leptin interaction in human cultured lutein granulosa cells steroidogenesis. Fertil. Steril. 90(4 Suppl): 1444-1450.
22. Viani, I., A. Vottero, F. Tassi, et al. 2008. Ghrelin inhibits steroid biosynthesis by cultured granulosa-lutein cells.JClin. Endocrinol. Metab. 93: 1476-1481.
23. Van Santbrink, E.J., W.C. Hop, T.J. van Dessel, et al. 1995. Decremental follicle-stimulating hormone and dominant follicle development during the normalmenstrual cycle. Fertil. Steril. 64: 37-43.
24. Templeton, A., I.E. Messinis & D.T. Baird. 1986. Characteristics of ovarian follicles in spontaneous and stimulated cycles in which there was an endogenous luteinizing hormone surge. Fertil. Steril. 46: 1113-1117.
25. Tajima, K., M. Orisaka, T. Mori & F. Kotsuji. 2007. Ovarian theca cells in follicular function. Reprod. Biomed. Online 15: 591-609.
26. Lindeberg, M., K. Carlström, O. Ritvos & O. Hovatta. 2007. Gonadotrophin stimulation of non-luteinized granulose cells increases steroid production and the expression of enzymes involved in estrogen and progesterone synthesis. Hum. Reprod. 22: 401-406.
27. Zeleznik, A.J. 2001. Follicle selection in primates:"many are called but few are chosen. " Biol. Reprod. 65: 655-659.
28. Mihm,M., P.J. Baker, J.L. Ireland, et al. 2006.Molecular evidence that growth of dominant follicles involves a reduction in follicle-stimulating hormone dependence and an increase in luteinizing hormone dependence in cattle. Biol. Reprod. 74: 1051-1059.
29. Baker, S.J.&N. Spears. 1999. The role of intra-ovarian interactions in the regulation of follicle dominance.Hum.Reprod. Update 5: 153-165.
30. Leroy, I., M. dAcremont, S. Brailly-Tabard, et al. 1994.Asingle injection of a gonadotropin-releasing hormone (GnRH) antagonist (Cetrorelix) postpones the luteinizing hormone (LH) surge: further evidence for the role of GnRH during the LH surge. Fertil. Steril. 62: 461-467.
31. Sullivan, M.W., A. Stewart-Akers, J.S. Krasnow, et al. 1999. Ovarian responses in women to recombinant folliclestimulating hormone and luteinizing hormone (LH): a role for LH in the final stages of follicular maturation. J. Clin. Endocrinol. Metab. 84: 228-232.
32. Durnerin, C.I., K. Erb, R. Fleming, et al. 2008. Effects of recombinant LH treatment on folliculogenesis and responsiveness to FSH stimulation. Hum. Reprod. 23: 421-426.
33. Shoham, Z., B.Mannaerts,V. Insler&H.Coelingh-Bennink. 1993. Induction of follicular growth using recombinant human follicle-stimulating hormone in two volunteer women with hypogonadotropic hypogonadism. Fertil. Steril. 59: 738-742.
34. Messinis, I.E. 2005. Ovulation induction: a mini review. Hum. Reprod. 20: 2688-2697.
35. Pakarainen, T., F.P. Zhang, L. Nurmi, et al. 2005. Knockout of luteinizing hormone receptor abolishes the effects of follicle-stimulating hormone on preovulatory maturation and ovulation of mouse graafian follicles. Mol. Endocrinol. 19: 2591-2602.
36. Messinis, I.E. 2006 Ovarian feedback, mechanism of action and possible clinical implications. Hum. Reprod. Update 12: 557-571.
37. Messinis, I.E., S. Milingos, K. Zikopoulos, et al. 1998. Luteinizing hormone response to gonadotrophin-releasing hormone in normalwomenundergoing ovulation induction with urinary or recombinant follicle stimulating hormone. Hum. Reprod. 13: 2415-2420.
38. Borm, G. & B. Mannaerts. 2000. Treatment with the gonadotrophin-releasing hormone antagonist ganirelix in women undergoing ovarian stimulation with recombinant follicle stimulating hormone is effective, safe and convenient: results of a controlled, randomized, multicentre trial. The European Orgalutran Study Group. Hum. Reprod. 15: 1490-1498.
39. Messinis, I.E. & A.A. Templeton. 1989. Pituitary response to exogenous LHRH in superovulated women. J. Reprod. Fertil. 87: 633-639.
40. Cedrin-Durnerin, I., J.M. Bidart, P. Robert, et al. 2000. Consequences on gonadotrophin secretion of an early discontinuation of gonadotrophin-releasing hormone agonist administration in short-termprotocol for in-vitro fertilization. Hum. Reprod. 15: 1009-1014.
41. Kolibianakis, E.M., J. Collins, B. Tarlatzis, et al. 2006. Are endogenousLHlevels during ovarian stimulation for IVF using GnRH analogues associated with the probability of ongoing pregnancy? A systematic review. Hum. Reprod. Update 12: 3-12.
42. Tarlatzis, B., E. Tavmergen,M. Szamatowicz, et al. 2006. The use of recombinant human LH (lutropin alfa) in the late stimulation phase of assisted reproduction cycles: a doubleblind, randomized, prospective study. Hum. Reprod. 21: 90-94.
43. Messinis, I.E., D. Loutradis, E. Domali, et al. 2005. Alternate day and daily administration of GnRH antagonist may prevent premature luteinization to a similar extent during FSH treatment. Hum. Reprod. 20: 3192-3197.
44. Messinis, I.E., P. Vanakara, A. Zavos, et al. 2010. Failure of theGnRHantagonist ganirelix to block the positive feedback effect of exogenous estrogen in normal women. Fertil. Steril. Feb 9 (Epub ahead of print).
45. Loumaye, E., P. Engrand, Z. Shoham, et al. 2003. Clinical evidence for an LH ceiling effect induced by administration of recombinant human LH during the late follicular phase of stimulated cycles in World Health Organization type I and type II anovulation. Hum. Reprod. 18: 314-322.
46. Richards, J.S. 1994. Hormonal control of gene expression in the ovary. Endocr. Rev. 15: 725-751.
47. Hugues, J.N., J. Soussis, I. Calderon, et al. 2005.Recombinant LH Study Group. Does the addition of recombinant LH in WHOgroup II anovulatorywomen over-responding to FSH treatment reduce the number of developing follicles?Adosefinding study. Hum. Reprod. 20: 629-635.