-
1
-
-
33845235459
-
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
-
Bartkova J, Rezaei N, Liontos M, Karakaidos P, Kletsas D, Issaeva N, Vassiliou LV, Kolettas E, Niforou K, Zoumpourlis VC, Takaoka M, Nakagawa H, Tort F, Fugger K, Johansson F, Sehested M, Andersen CL, Dyrskjot L, Orntoft T, Lukas J, Kittas C, Helleday T, Halazonetis TD, Bartek J, and Gorgoulis VG. Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints. Nature 444: 633-637, 2006.
-
(2006)
Nature
, vol.444
, pp. 633-637
-
-
Bartkova, J.1
Rezaei, N.2
Liontos, M.3
Karakaidos, P.4
Kletsas, D.5
Issaeva, N.6
Vassiliou, L.V.7
Kolettas, E.8
Niforou, K.9
Zoumpourlis, V.C.10
Takaoka, M.11
Nakagawa, H.12
Tort, F.13
Fugger, K.14
Johansson, F.15
Sehested, M.16
Andersen, C.L.17
Dyrskjot, L.18
Orntoft, T.19
Lukas, J.20
Kittas, C.21
Helleday, T.22
Halazonetis, T.D.23
Bartek, J.24
Gorgoulis, V.G.25
more..
-
2
-
-
0025642434
-
Transformed and nontransformed cells differ in stability and cell cycle regulation of a binding activity to the murine thymidine kinase promoter
-
Bradley DW, Dou QP, Fridovich-Keil JL, and Pardee AB. Transformed and nontransformed cells differ in stability and cell cycle regulation of a binding activity to the murine thymidine kinase promoter. Proc Natl Acad Sci U S A 87: 9310-9314, 1990.
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 9310-9314
-
-
Bradley, D.W.1
Dou, Q.P.2
Fridovich-Keil, J.L.3
Pardee, A.B.4
-
3
-
-
53749108053
-
Short telomeres, telomerase reverse transcriptase gene amplification, and increased telomerase activity in the blood of familial papillary thyroid cancer patients
-
Capezzone M, Cantara S, Marchisotta S, Filetti S, De Santi MM, Rossi B, Ronga G, Durante C, and Pacini F. Short telomeres, telomerase reverse transcriptase gene amplification, and increased telomerase activity in the blood of familial papillary thyroid cancer patients. J Clin Endocrinol Metab 93: 3950-3957, 2008.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 3950-3957
-
-
Capezzone, M.1
Cantara, S.2
Marchisotta, S.3
Filetti, S.4
De Santi, M.M.5
Rossi, B.6
Ronga, G.7
Durante, C.8
Pacini, F.9
-
4
-
-
0030902506
-
Tpl-2 is an oncogenic kinase that is activated by carboxyterminal truncation
-
Ceci JD, Patriotis CP, Tsatsanis C, Makris AM, Kovatch R, Swing DA, Jenkins NA, Tsichlis PN, and Copeland NG. Tpl-2 is an oncogenic kinase that is activated by carboxyterminal truncation. Genes Dev 11: 688-700, 1997.
-
(1997)
Genes Dev
, vol.11
, pp. 688-700
-
-
Ceci, J.D.1
Patriotis, C.P.2
Tsatsanis, C.3
Makris, A.M.4
Kovatch, R.5
Swing, D.A.6
Jenkins, N.A.7
Tsichlis, P.N.8
Copeland, N.G.9
-
5
-
-
33845269825
-
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
-
Di Micco R, Fumagalli M, Cicalese A, Piccinin S, Gasparini P, Luise C, Schurra C, Garre M, Nuciforo PG, Bensimon A, Maestro R, Pelicci PG, and d'Adda di Fagagna F. Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication. Nature 444: 638-642, 2006.
-
(2006)
Nature
, vol.444
, pp. 638-642
-
-
Di Micco, R.1
Fumagalli, M.2
Cicalese, A.3
Piccinin, S.4
Gasparini, P.5
Luise, C.6
Schurra, C.7
Garre, M.8
Nuciforo, P.G.9
Bensimon, A.10
Maestro, R.11
Pelicci, P.G.12
D'adda Di Fagagna, F.13
-
6
-
-
0345036072
-
DNA damage related to increased hydrogen peroxide generation by hypolipidemic drug-induced liver peroxisomes
-
Fahl WE, Lalwani ND, Watanabe T, Goel SK, and Reddy JK. DNA damage related to increased hydrogen peroxide generation by hypolipidemic drug-induced liver peroxisomes. Proc Natl Acad Sci U S A 81: 7827-7830, 1984.
-
(1984)
Proc Natl Acad Sci U S A
, vol.81
, pp. 7827-7830
-
-
Fahl, W.E.1
Lalwani, N.D.2
Watanabe, T.3
Goel, S.K.4
Reddy, J.K.5
-
7
-
-
0032954805
-
Extracellular superoxide dismutase in the airways of transgenic mice reduces inflammation and attenuates lung toxicity following hyperoxia
-
Folz RJ, Abushamaa AM, and Suliman HB. Extracellular superoxide dismutase in the airways of transgenic mice reduces inflammation and attenuates lung toxicity following hyperoxia. J Clin Invest 103: 1055-1066, 1999.
-
(1999)
J Clin Invest
, vol.103
, pp. 1055-1066
-
-
Folz, R.J.1
Abushamaa, A.M.2
Suliman, H.B.3
-
8
-
-
0022486653
-
In vitro establishment is not a sufficient prerequisite for transformation by activated ras oncogenes
-
Franza BR, Jr., Maruyama K, Garrels JI, and Ruley HE. In vitro establishment is not a sufficient prerequisite for transformation by activated ras oncogenes. Cell 44: 409-418, 1986.
-
(1986)
Cell
, vol.44
, pp. 409-418
-
-
Franza, B.R.1
Maruyama, K.2
Garrels, J.I.3
Ruley, H.E.4
-
9
-
-
33646268429
-
Delineation, functional validation, and bioinformatic evaluation of gene expression in thyroid follicular carcinomas with the PAX8-PPARG translocation
-
Giordano TJ, Au AY, Kuick R, Thomas DG, Rhodes DR, Wilhelm KG, Jr., Vinco M, Misek DE, Sanders D, Zhu Z, Ciampi R, Hanash S, Chinnaiyan A, Clifton-Bligh RJ, Robinson BG, Nikiforov YE, and Koenig RJ. Delineation, functional validation, and bioinformatic evaluation of gene expression in thyroid follicular carcinomas with the PAX8-PPARG translocation. Clin Cancer Res 12: 1983-1993, 2006.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 1983-1993
-
-
Giordano, T.J.1
Au, A.Y.2
Kuick, R.3
Thomas, D.G.4
Rhodes, D.R.5
Wilhelm, K.G.6
Vinco, M.7
Misek, D.E.8
Sanders, D.9
Zhu, Z.10
Ciampi, R.11
Hanash, S.12
Chinnaiyan, A.13
Clifton-Bligh, R.J.14
Robinson, B.G.15
Nikiforov, Y.E.16
Koenig, R.J.17
-
10
-
-
40449120350
-
An oncogene-induced DNA damage model for cancer development
-
Halazonetis TD, Gorgoulis VG, and Bartek J. An oncogene-induced DNA damage model for cancer development. Science 319: 1352-1355, 2008.
-
(2008)
Science
, vol.319
, pp. 1352-1355
-
-
Halazonetis, T.D.1
Gorgoulis, V.G.2
Bartek, J.3
-
11
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D and Weinberg RA. Hallmarks of cancer: the next generation. Cell 144: 646-674, 2011.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
12
-
-
33645511274
-
Activation of canonical Wnt pathway promotes proliferation of retinal stem cells derived from adult mouse ciliary margin
-
Inoue T, Kagawa T, Fukushima M, Shimizu T, Yoshinaga Y, Takada S, Tanihara H, and Taga T. Activation of canonical Wnt pathway promotes proliferation of retinal stem cells derived from adult mouse ciliary margin. Stem Cells 24: 95-104, 2006.
-
(2006)
Stem Cells
, vol.24
, pp. 95-104
-
-
Inoue, T.1
Kagawa, T.2
Fukushima, M.3
Shimizu, T.4
Yoshinaga, Y.5
Takada, S.6
Tanihara, H.7
Taga, T.8
-
13
-
-
0030980641
-
Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts
-
Irani K, Xia Y, Zweier JL, Sollott SJ, Der CJ, Fearon ER, Sundaresan M, Finkel T, and Goldschmidt-Clermont PJ. Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts. Science 275: 1649-1652, 1997.
-
(1997)
Science
, vol.275
, pp. 1649-1652
-
-
Irani, K.1
Xia, Y.2
Zweier, J.L.3
Sollott, S.J.4
Der, C.J.5
Fearon, E.R.6
Sundaresan, M.7
Finkel, T.8
Goldschmidt-Clermont, P.J.9
-
14
-
-
0025276807
-
CDNA cloning and characterization of ret activated in a human papillary thyroid carcinoma cell line
-
Ishizaka Y, Ushijima T, Sugimura T, and Nagao M. cDNA cloning and characterization of ret activated in a human papillary thyroid carcinoma cell line. Biochem Biophys Res Commun 168: 402-408, 1990.
-
(1990)
Biochem Biophys Res Commun
, vol.168
, pp. 402-408
-
-
Ishizaka, Y.1
Ushijima, T.2
Sugimura, T.3
Nagao, M.4
-
15
-
-
0030052368
-
Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS
-
Joneson T, White MA, Wigler MH, and Bar-Sagi D. Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS. Science 271: 810-812, 1996.
-
(1996)
Science
, vol.271
, pp. 810-812
-
-
Joneson, T.1
White, M.A.2
Wigler, M.H.3
Bar-Sagi, D.4
-
16
-
-
39749137048
-
Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer
-
Kaiser S, Park YK, Franklin JL, Halberg RB, Yu M, Jessen WJ, Freudenberg J, Chen X, Haigis K, Jegga AG, Kong S, Sakthivel B, Xu H, Reichling T, Azhar M, Boivin GP, Roberts RB, Bissahoyo AC, Gonzales F, Bloom GC, Eschrich S, Carter SL, Aronow JE, Kleimeyer J, Kleimeyer M, Ramaswamy V, Settle SH, Boone B, Levy S, Graff JM, Doetschman T, Groden J, Dove WF, Threadgill DW, Yeatman TJ, Coffey RJ, Jr., and Aronow BJ. Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer. Genome Biol 8: R131, 2007.
-
(2007)
Genome Biol
, vol.8
, pp. R131
-
-
Kaiser, S.1
Park, Y.K.2
Franklin, J.L.3
Halberg, R.B.4
Yu, M.5
Jessen, W.J.6
Freudenberg, J.7
Chen, X.8
Haigis, K.9
Jegga, A.G.10
Kong, S.11
Sakthivel, B.12
Xu, H.13
Reichling, T.14
Azhar, M.15
Boivin, G.P.16
Roberts, R.B.17
Bissahoyo, A.C.18
Gonzales, F.19
Bloom, G.C.20
Eschrich, S.21
Carter, S.L.22
Aronow, J.E.23
Kleimeyer, J.24
Kleimeyer, M.25
Ramaswamy, V.26
Settle, S.H.27
Boone, B.28
Levy, S.29
Graff, J.M.30
Doetschman, T.31
Groden, J.32
Dove, W.F.33
Threadgill, D.W.34
Yeatman, T.J.35
Coffey, R.J.36
Aronow, B.J.37
more..
-
17
-
-
77950219816
-
FOXQ1 is overexpressed in colorectal cancer and enhances tumorigenicity and tumor growth
-
Kaneda H, Arao T, Tanaka K, Tamura D, Aomatsu K, Kudo K, Sakai K, De Velasco MA, Matsumoto K, Fujita Y, Yamada Y, Tsurutani J, Okamoto I, Nakagawa K, and Nishio K. FOXQ1 is overexpressed in colorectal cancer and enhances tumorigenicity and tumor growth. Cancer Res 70: 2053-2063, 2010.
-
(2010)
Cancer Res
, vol.70
, pp. 2053-2063
-
-
Kaneda, H.1
Arao, T.2
Tanaka, K.3
Tamura, D.4
Aomatsu, K.5
Kudo, K.6
Sakai, K.7
De Velasco, M.A.8
Matsumoto, K.9
Fujita, Y.10
Yamada, Y.11
Tsurutani, J.12
Okamoto, I.13
Nakagawa, K.14
Nishio, K.15
-
18
-
-
32044460439
-
Overexpression of extracellular superoxide dismutase (EC-SOD) in mouse skin plays a protective role in DMBA/ TPA-induced tumor formation
-
Kim SH, Kim MO, Gao P, Youm CA, Park HR, Lee TS, Kim KS, Suh JG, Lee HT, Park BJ, Ryoo ZY, and Lee TH. Overexpression of extracellular superoxide dismutase (EC-SOD) in mouse skin plays a protective role in DMBA/ TPA-induced tumor formation. Oncol Res 15: 333-341, 2005.
-
(2005)
Oncol Res
, vol.15
, pp. 333-341
-
-
Kim, S.H.1
Kim, M.O.2
Gao, P.3
Youm, C.A.4
Park, H.R.5
Lee, T.S.6
Kim, K.S.7
Suh, J.G.8
Lee, H.T.9
Park, B.J.10
Ryoo, Z.Y.11
Lee, T.H.12
-
19
-
-
77956380952
-
Extracellular superoxide dismutase is a thyroid differentiation marker down-regulated in cancer
-
Laatikainen LE, Castellone MD, Hebrant A, Hoste C, Cantisani MC, Laurila JP, Salvatore G, Salerno P, Basolo F, Nasman J, Dumont JE, Santoro M, and Laukkanen MO. Extracellular superoxide dismutase is a thyroid differentiation marker down-regulated in cancer. Endocr Relat Cancer 17: 785-796, 2010.
-
(2010)
Endocr Relat Cancer
, vol.17
, pp. 785-796
-
-
Laatikainen, L.E.1
Castellone, M.D.2
Hebrant, A.3
Hoste, C.4
Cantisani, M.C.5
Laurila, J.P.6
Salvatore, G.7
Salerno, P.8
Basolo, F.9
Nasman, J.10
Dumont, J.E.11
Santoro, M.12
Laukkanen, M.O.13
-
20
-
-
80052312525
-
SOD3 decreases ischemic injury derived apoptosis through phosphorylation of Erk1/ 2, Akt, and FoxO3a
-
Laatikainen LE, Incoronato M, Castellone MD, Laurila JP, Santoro M, and Laukkanen MO. SOD3 decreases ischemic injury derived apoptosis through phosphorylation of Erk1/ 2, Akt, and FoxO3a. PLoS One 6: e24456.
-
PLoS One
, vol.6
, pp. e24456
-
-
Laatikainen, L.E.1
Incoronato, M.2
Castellone, M.D.3
Laurila, J.P.4
Santoro, M.5
Laukkanen, M.O.6
-
21
-
-
0037044416
-
Adenovirus-mediated extracellular superoxide dismutase gene therapy reduces neointima formation in balloondenuded rabbit aorta
-
Laukkanen MO, Kivela A, Rissanen T, Rutanen J, Karkkainen MK, Leppanen O, Brasen JH, and Yla-Herttuala S. Adenovirus-mediated extracellular superoxide dismutase gene therapy reduces neointima formation in balloondenuded rabbit aorta. Circulation 106: 1999-2003, 2002.
-
(2002)
Circulation
, vol.106
, pp. 1999-2003
-
-
Laukkanen, M.O.1
Kivela, A.2
Rissanen, T.3
Rutanen, J.4
Karkkainen, M.K.5
Leppanen, O.6
Brasen, J.H.7
Yla-Herttuala, S.8
-
22
-
-
0034702876
-
Rabbit extracellular superoxide dismutase: Expression and effect on LDL oxidation
-
Laukkanen MO, Lehtolainen P, Turunen P, Aittomaki S, Oikari P, Marklund SL, and Yla-Herttuala S. Rabbit extracellular superoxide dismutase: expression and effect on LDL oxidation. Gene 254: 173-179, 2000.
-
(2000)
Gene
, vol.254
, pp. 173-179
-
-
Laukkanen, M.O.1
Lehtolainen, P.2
Turunen, P.3
Aittomaki, S.4
Oikari, P.5
Marklund, S.L.6
Yla-Herttuala, S.7
-
23
-
-
0035404419
-
EC-SOD gene therapy reduces paracetamol-induced liver damage in mice
-
Laukkanen MO, Leppanen P, Turunen P, Tuomisto T, Naarala J, and Yla-Herttuala S. EC-SOD gene therapy reduces paracetamol-induced liver damage in mice. J Gene Med 3: 321-325, 2001.
-
(2001)
J Gene Med
, vol.3
, pp. 321-325
-
-
Laukkanen, M.O.1
Leppanen, P.2
Turunen, P.3
Tuomisto, T.4
Naarala, J.5
Yla-Herttuala, S.6
-
24
-
-
61649125373
-
Extracellular superoxide dismutase is a growth regulatory mediator of tissue injury recovery
-
Laurila JP, Castellone MD, Curcio A, Laatikainen LE, Haaparanta-Solin M, Gronroos TJ, Marjamaki P, Martikainen S, Santoro M, and Laukkanen MO. Extracellular superoxide dismutase is a growth regulatory mediator of tissue injury recovery. Mol Ther 17: 448-454, 2009.
-
(2009)
Mol Ther
, vol.17
, pp. 448-454
-
-
Laurila, J.P.1
Castellone, M.D.2
Curcio, A.3
Laatikainen, L.E.4
Haaparanta-Solin, M.5
Gronroos, T.J.6
Marjamaki, P.7
Martikainen, S.8
Santoro, M.9
Laukkanen, M.O.10
-
25
-
-
0033583242
-
Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species
-
Lee AC, Fenster BE, Ito H, Takeda K, Bae NS, Hirai T, Yu ZX, Ferrans VJ, Howard BH, and Finkel T. Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species. J Biol Chem 274: 7936-7940, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 7936-7940
-
-
Lee, A.C.1
Fenster, B.E.2
Ito, H.3
Takeda, K.4
Bae, N.S.5
Hirai, T.6
Yu, Z.X.7
Ferrans, V.J.8
Howard, B.H.9
Finkel, T.10
-
26
-
-
77953160837
-
A novel senescence-evasion mechanism involving Grap2 and Cyclin D interacting protein inactivation by Ras associated with diabetes in cancer cells under doxorubicin treatment
-
Lee I, Yeom SY, Lee SJ, Kang WK, and Park C. A novel senescence-evasion mechanism involving Grap2 and Cyclin D interacting protein inactivation by Ras associated with diabetes in cancer cells under doxorubicin treatment. Cancer Res 70: 4357-4365, 2010.
-
(2010)
Cancer Res
, vol.70
, pp. 4357-4365
-
-
Lee, I.1
Yeom, S.Y.2
Lee, S.J.3
Kang, W.K.4
Park, C.5
-
27
-
-
0006157248
-
Human copper-containing superoxide dismutase of high molecular weight
-
Marklund SL. Human copper-containing superoxide dismutase of high molecular weight. Proc Natl Acad Sci U S A 79: 7634-7638, 1982.
-
(1982)
Proc Natl Acad Sci U S A
, vol.79
, pp. 7634-7638
-
-
Marklund, S.L.1
-
28
-
-
0032484084
-
Linkage of ATM to cell cycle regulation by the Chk2 protein kinase
-
Matsuoka S, Huang M, and Elledge SJ. Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. Science 282: 1893-1897, 1998.
-
(1998)
Science
, vol.282
, pp. 1893-1897
-
-
Matsuoka, S.1
Huang, M.2
Elledge, S.J.3
-
29
-
-
65949119310
-
How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?
-
Mebratu Y and Tesfaigzi Y. How ERK1/2 activation controls cell proliferation and cell death: is subcellular localization the answer? Cell Cycle 8: 1168-1175, 2009.
-
(2009)
Cell Cycle
, vol.8
, pp. 1168-1175
-
-
Mebratu, Y.1
Tesfaigzi, Y.2
-
30
-
-
23244447037
-
BRAFE600-associated senescence-like cell cycle arrest of human naevi
-
Michaloglou C, Vredeveld LC, Soengas MS, Denoyelle C, Kuilman T, van der Horst CM, Majoor DM, Shay JW, Mooi WJ, and Peeper DS. BRAFE600-associated senescence-like cell cycle arrest of human naevi. Nature 436: 720-724, 2005.
-
(2005)
Nature
, vol.436
, pp. 720-724
-
-
Michaloglou, C.1
Vredeveld, L.C.2
Soengas, M.S.3
Denoyelle, C.4
Kuilman, T.5
Van Der Horst, C.M.6
Majoor, D.M.7
Shay, J.W.8
Mooi, W.J.9
Peeper, D.S.10
-
31
-
-
2442693092
-
The superoxidegenerating oxidase Nox1 is functionally required for Ras oncogene transformation
-
Mitsushita J, Lambeth JD, and Kamata T. The superoxidegenerating oxidase Nox1 is functionally required for Ras oncogene transformation. Cancer Res 64: 3580-3585, 2004.
-
(2004)
Cancer Res
, vol.64
, pp. 3580-3585
-
-
Mitsushita, J.1
Lambeth, J.D.2
Kamata, T.3
-
32
-
-
0020521611
-
Fibroblast immortality is a prerequisite for transformation by EJ c-Ha-ras oncogene
-
Newbold RF and Overell RW. Fibroblast immortality is a prerequisite for transformation by EJ c-Ha-ras oncogene. Nature 304: 648-651, 1983.
-
(1983)
Nature
, vol.304
, pp. 648-651
-
-
Newbold, R.F.1
Overell, R.W.2
-
33
-
-
77956328596
-
Extracellular SOD-derived H2O2 promotes VEGF signaling in caveolae/lipid rafts and post-ischemic angiogenesis in mice
-
Oshikawa J, Urao N, Kim HW, Kaplan N, Razvi M, McKinney R, Poole LB, Fukai T, and Ushio-Fukai M. Extracellular SOD-derived H2O2 promotes VEGF signaling in caveolae/lipid rafts and post-ischemic angiogenesis in mice. PLoS One 5: e10189, 2010.
-
(2010)
PLoS One
, vol.5
, pp. e10189
-
-
Oshikawa, J.1
Urao, N.2
Kim, H.W.3
Kaplan, N.4
Razvi, M.5
McKinney, R.6
Poole, L.B.7
Fukai, T.8
Ushio-Fukai, M.9
-
34
-
-
0035156849
-
Escape from premature senescence is not sufficient for oncogenic transformation by Ras
-
Peeper DS, Dannenberg JH, Douma S, te Riele H, and Bernards R. Escape from premature senescence is not sufficient for oncogenic transformation by Ras. Nat Cell Biol 3: 198-203, 2001.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 198-203
-
-
Peeper, D.S.1
Dannenberg, J.H.2
Douma, S.3
Te Riele, H.4
Bernards, R.5
-
35
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou CM, Sorlie T, Eisen MB, van de Rijn M, Jeffrey SS, Rees CA, Pollack JR, Ross DT, Johnsen H, Akslen LA, Fluge O, Pergamenschikov A, Williams C, Zhu SX, Lonning PE, Borresen-Dale AL, Brown PO, and Botstein D. Molecular portraits of human breast tumours. Nature 406: 747-752, 2000.
-
(2000)
Nature
, vol.406
, pp. 747-752
-
-
Perou, C.M.1
Sorlie, T.2
Eisen, M.B.3
Van De Rijn, M.4
Jeffrey, S.S.5
Rees, C.A.6
Pollack, J.R.7
Ross, D.T.8
Johnsen, H.9
Akslen, L.A.10
Fluge, O.11
Pergamenschikov, A.12
Williams, C.13
Zhu, S.X.14
Lonning, P.E.15
Borresen-Dale, A.L.16
Brown, P.O.17
Botstein, D.18
-
36
-
-
1342288971
-
Opinion: Comparative biology of mouse versus human cells: Modelling human cancer in mice
-
Rangarajan A and Weinberg RA. Opinion: comparative biology of mouse versus human cells: modelling human cancer in mice. Nat Rev Cancer 3: 952-959, 2003.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 952-959
-
-
Rangarajan, A.1
Weinberg, R.A.2
-
37
-
-
0015732254
-
Quantitative and qualitative studies of chemical transformation of cloned C3H mouse embryo cells sensitive to postconfluence inhibition of cell division
-
Reznikoff CA, Bertram JS, Brankow DW, and Heidelberger C. Quantitative and qualitative studies of chemical transformation of cloned C3H mouse embryo cells sensitive to postconfluence inhibition of cell division. Cancer Res 33: 3239-3249, 1973.
-
(1973)
Cancer Res
, vol.33
, pp. 3239-3249
-
-
Reznikoff, C.A.1
Bertram, J.S.2
Brankow, D.W.3
Heidelberger, C.4
-
38
-
-
37849013557
-
Transcriptome profile of human colorectal adenomas
-
Sabates-Bellver J, Van der Flier LG, de Palo M, Cattaneo E, Maake C, Rehrauer H, Laczko E, Kurowski MA, Bujnicki JM, Menigatti M, Luz J, Ranalli TV, Gomes V, Pastorelli A, Faggiani R, Anti M, Jiricny J, Clevers H, and Marra G. Transcriptome profile of human colorectal adenomas. Mol Cancer Res 5: 1263-1275, 2007.
-
(2007)
Mol Cancer Res
, vol.5
, pp. 1263-1275
-
-
Sabates-Bellver, J.1
Van Der Flier, L.G.2
De Palo, M.3
Cattaneo, E.4
Maake, C.5
Rehrauer, H.6
Laczko, E.7
Kurowski, M.A.8
Bujnicki, J.M.9
Menigatti, M.10
Luz, J.11
Ranalli, T.V.12
Gomes, V.13
Pastorelli, A.14
Faggiani, R.15
Anti, M.16
Jiricny, J.17
Clevers, H.18
Marra, G.19
-
39
-
-
34247897276
-
Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis
-
Sarkisian CJ, Keister BA, Stairs DB, Boxer RB, Moody SE, and Chodosh LA. Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis. Nat Cell Biol 9: 493-505, 2007.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 493-505
-
-
Sarkisian, C.J.1
Keister, B.A.2
Stairs, D.B.3
Boxer, R.B.4
Moody, S.E.5
Chodosh, L.A.6
-
40
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
-
Serrano M, Lin AW, McCurrach ME, Beach D, and Lowe SW. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 88: 593-602, 1997.
-
(1997)
Cell
, vol.88
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
41
-
-
0030871667
-
Highintensity Raf signal causes cell cycle arrest mediated by p21Cip1
-
Sewing A, Wiseman B, Lloyd AC, and Land H. Highintensity Raf signal causes cell cycle arrest mediated by p21Cip1. Mol Cell Biol 17: 5588-5597, 1997.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 5588-5597
-
-
Sewing, A.1
Wiseman, B.2
Lloyd, A.C.3
Land, H.4
-
42
-
-
35348944457
-
Roles of hydrogen peroxide in thyroid physiology and disease
-
Song Y, Driessens N, Costa M, De Deken X, Detours V, Corvilain B, Maenhaut C, Miot F, Van Sande J, Many MC, and Dumont JE. Roles of hydrogen peroxide in thyroid physiology and disease. J Clin Endocrinol Metab 92: 3764-3773, 2007.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 3764-3773
-
-
Song, Y.1
Driessens, N.2
Costa, M.3
De Deken, X.4
Detours, V.5
Corvilain, B.6
Maenhaut, C.7
Miot, F.8
Van Sande, J.9
Many, M.C.10
Dumont, J.E.11
-
43
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
Sorlie T, Perou CM, Tibshirani R, Aas T, Geisler S, Johnsen H, Hastie T, Eisen MB, van de Rijn M, Jeffrey SS, Thorsen T, Quist H, Matese JC, Brown PO, Botstein D, Lonning PE, and Borresen-Dale AL. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A 98: 10869-10874, 2001.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 10869-10874
-
-
Sorlie, T.1
Perou, C.M.2
Tibshirani, R.3
Aas, T.4
Geisler, S.5
Johnsen, H.6
Hastie, T.7
Eisen, M.B.8
Van De Rijn, M.9
Jeffrey, S.S.10
Thorsen, T.11
Quist, H.12
Matese, J.C.13
Brown, P.O.14
Botstein, D.15
Lonning, P.E.16
Borresen-Dale, A.L.17
-
44
-
-
0037478605
-
Repeated observation of breast tumor subtypes in independent gene expression data sets
-
Sorlie T, Tibshirani R, Parker J, Hastie T, Marron JS, Nobel A, Deng S, Johnsen H, Pesich R, Geisler S, Demeter J, Perou CM, Lonning PE, Brown PO, Borresen-Dale AL, and Botstein D. Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci U S A 100: 8418-8423, 2003.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 8418-8423
-
-
Sorlie, T.1
Tibshirani, R.2
Parker, J.3
Hastie, T.4
Marron, J.S.5
Nobel, A.6
Deng, S.7
Johnsen, H.8
Pesich, R.9
Geisler, S.10
Demeter, J.11
Perou, C.M.12
Lonning, P.E.13
Brown, P.O.14
Borresen-Dale, A.L.15
Botstein, D.16
-
45
-
-
78549268199
-
Intrinsic cooperation between p16INK4a and p21Waf1/Cip1 in the onset of cellular senescence and tumor suppression in vivo
-
Takeuchi S, Takahashi A, Motoi N, Yoshimoto S, Tajima T, Yamakoshi K, Hirao A, Yanagi S, Fukami K, Ishikawa Y, Sone S, Hara E, and Ohtani N. Intrinsic cooperation between p16INK4a and p21Waf1/Cip1 in the onset of cellular senescence and tumor suppression in vivo. Cancer Res 70: 9381-9390, 2010.
-
(2010)
Cancer Res
, vol.70
, pp. 9381-9390
-
-
Takeuchi, S.1
Takahashi, A.2
Motoi, N.3
Yoshimoto, S.4
Tajima, T.5
Yamakoshi, K.6
Hirao, A.7
Yanagi, S.8
Fukami, K.9
Ishikawa, Y.10
Sone, S.11
Hara, E.12
Ohtani, N.13
-
46
-
-
78650016651
-
Monoclonal antibody targeting of N-cadherin inhibits prostate cancer growth, metastasis and castration resistance
-
Tanaka H, Kono E, Tran CP, Miyazaki H, Yamashiro J, Shimomura T, Fazli L, Wada R, Huang J, Vessella RL, An J, Horvath S, Gleave M, Rettig MB, Wainberg ZA, and Reiter RE. Monoclonal antibody targeting of N-cadherin inhibits prostate cancer growth, metastasis and castration resistance. Nat Med 16: 1414-1420, 2010.
-
(2010)
Nat Med
, vol.16
, pp. 1414-1420
-
-
Tanaka, H.1
Kono, E.2
Tran, C.P.3
Miyazaki, H.4
Yamashiro, J.5
Shimomura, T.6
Fazli, L.7
Wada, R.8
Huang, J.9
Vessella, R.L.10
An, J.11
Horvath, S.12
Gleave, M.13
Rettig, M.B.14
Wainberg, Z.A.15
Reiter, R.E.16
-
47
-
-
0035138146
-
Anti-metastatic gene therapy utilizing subcutaneous inoculation of EC-SOD gene transduced autologous fibroblast suppressed lung metastasis of Meth-A cells and 3LL cells in mice
-
Tanaka M, Kogawa K, Nakamura K, Nishihori Y, Kuribayashi K, Hagiwara S, Muramatsu H, Sakamaki S, and Niitsu Y. Anti-metastatic gene therapy utilizing subcutaneous inoculation of EC-SOD gene transduced autologous fibroblast suppressed lung metastasis of Meth-A cells and 3LL cells in mice. Gene Ther 8: 149-156, 2001.
-
(2001)
Gene Ther
, vol.8
, pp. 149-156
-
-
Tanaka, M.1
Kogawa, K.2
Nakamura, K.3
Nishihori, Y.4
Kuribayashi, K.5
Hagiwara, S.6
Muramatsu, H.7
Sakamaki, S.8
Niitsu, Y.9
-
48
-
-
28444466930
-
Spontaneously immortalized mouse embryo fibroblasts: Growth behavior of wild-type and vimentin-deficient cells in relation to mitochondrial structure and activity
-
Tolstonog GV, Belichenko-Weitzmann IV, Lu JP, Hartig R, Shoeman RL, Traub U, and Traub P. Spontaneously immortalized mouse embryo fibroblasts: growth behavior of wild-type and vimentin-deficient cells in relation to mitochondrial structure and activity. DNA Cell Biol 24: 680-709, 2005.
-
(2005)
DNA Cell Biol
, vol.24
, pp. 680-709
-
-
Tolstonog, G.V.1
Belichenko-Weitzmann, I.V.2
Lu, J.P.3
Hartig, R.4
Shoeman, R.L.5
Traub, U.6
Traub, P.7
-
49
-
-
84855947011
-
Evidence of oncogene-induced senescence in thyroid carcinogenesis
-
Vizioli MG, Possik PA, Tarantino E, Meissl K, Borrello MG, Miranda C, Anania MC, Pagliardini S, Seregni E, Pierotti MA, Pilotti S, Peeper DS, and Greco A. Evidence of oncogene-induced senescence in thyroid carcinogenesis. Endocr Relat Cancer 18: 743-757, 2011.
-
(2011)
Endocr Relat Cancer
, vol.18
, pp. 743-757
-
-
Vizioli, M.G.1
Possik, P.A.2
Tarantino, E.3
Meissl, K.4
Borrello, M.G.5
Miranda, C.6
Anania, M.C.7
Pagliardini, S.8
Seregni, E.9
Pierotti, M.A.10
Pilotti, S.11
Peeper, D.S.12
Greco, A.13
-
50
-
-
0142120588
-
Secretion of extracellular superoxide dismutase from muscle transduced with recombinant adenovirus inhibits the growth of B16 melanomas in mice
-
Wheeler MD, Smutney OM, and Samulski RJ. Secretion of extracellular superoxide dismutase from muscle transduced with recombinant adenovirus inhibits the growth of B16 melanomas in mice. Mol Cancer Res 1: 871-881, 2003.
-
(2003)
Mol Cancer Res
, vol.1
, pp. 871-881
-
-
Wheeler, M.D.1
Smutney, O.M.2
Samulski, R.J.3
-
52
-
-
41049102001
-
Preparation culture, and immortalization of mouse embryonic fibroblasts. Curr Protoc Mol Biol Chapter 28
-
Xu J. Preparation, culture, and immortalization of mouse embryonic fibroblasts. Curr Protoc Mol Biol Chapter 28: Unit 28 21, 2005.
-
(2005)
Unit
, vol.28
, pp. 21
-
-
Xu, J.1
-
53
-
-
84866376633
-
MicroRNA-21 modulates the levels of reactive oxygen species by targeting SOD3 and TNFalpha
-
Zhang X, Ng WL, Wang P, Tian L, Werner E, Wang H, Doetsch P, and Wang Y. MicroRNA-21 modulates the levels of reactive oxygen species by targeting SOD3 and TNFalpha. Cancer Res 72: 4707-4713, 2012.
-
(2012)
Cancer Res
, vol.72
, pp. 4707-4713
-
-
Zhang, X.1
Ng, W.L.2
Wang, P.3
Tian, L.4
Werner, E.5
Wang, H.6
Doetsch, P.7
Wang, Y.8
-
54
-
-
29244449848
-
Stepwise neoplastic transformation of a telomerase immortalized fibroblast cell line
-
Zongaro S, de Stanchina E, Colombo T, D'Incalci M, Giulotto E, and Mondello C. Stepwise neoplastic transformation of a telomerase immortalized fibroblast cell line. Cancer Res 65: 11411-11418, 2005.
-
(2005)
Cancer Res
, vol.65
, pp. 11411-11418
-
-
Zongaro, S.1
De Stanchina, E.2
Colombo, T.3
D'incalci, M.4
Giulotto, E.5
Mondello, C.6
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