Extracellular superoxide dismutase is a thyroid differentiation marker down-regulated in cancer

Endocrine-Related Cancer

Volumn 17, Issue 3, 2010, Pages 785-796

  Laatikainen, Lilja E ^a   Castellone, Maria D ^b   Hebrant, Aline ^c   Hoste, Candice ^c   Cantisani, Maria C ^b   Laurila, Juha P ^a   Salvatore, Giuliana ^d   Salerno, Paolo ^b   Basolo, Fulvio ^e   Näsman, Johnny ^f   Dumont, Jacques E ^c   Santoro, Massimo ^b   Laukkanen, Mikko O ^a,g  

^a UNIVERSITY OF TURKU   (Finland)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^d UNIVERSITY OF NAPLES PARTHENOPE   (Italy)

^e UNIVERSITY OF PISA   (Italy)

^f ÅBO AKADEMI UNIVERSITY   (Finland)

^g IRCCS SDN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; BROXURIDINE; CALCIUM ION; COMPLEMENTARY DNA; COPPER ZINC SUPEROXIDE DISMUTASE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; DOXYCYCLINE; EXTRACELLULAR SUPEROXIDE DISMUTASE; FORSKOLIN; HYDROGEN PEROXIDE; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHOSPHOLIPASE C; PROPYLTHIOURACIL; THAPSIGARGIN; THYROTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CARCINOGENESIS; CELL DIFFERENTIATION; CELL PROLIFERATION; CHEMOLUMINESCENCE; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; FLUOROMETRY; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN TISSUE; MALE; MOUSE; NONHUMAN; ONCOGENE RET; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; THYROID CANCER;

EID: 77956380952     PISSN: 13510088     EISSN: 14796821     Source Type: Journal    
DOI: 10.1677/ERC-10-0021     Document Type: Article

References (48)

1. Abalovich M, Llesuy S, Gutierrez S & Repetto M 2003 Peripheral parameters of oxidative stress in Graves' disease: the effects of methimazole and 131 iodine treatments. Clinical Endocrinology 59 321-327. (Pubitemid 37046985)
2. al-Alawi N, Rose DW, Buckmaster C, Ahn N, Rapp U, Meinkoth J & Feramisco JR 1995 Thyrotropin-induced mitogenesis is Ras dependent but appears to bypass the Raf-dependent cytoplasmic kinase cascade. Molecular Cell Biology 15 1162-1168.
3. Aslan M & Ozben T 2003 Oxidants in receptor tyrosine kinase signal transduction pathways. Antioxidants & Redox Signaling 5 5781-5788.
4. Benard B & Brault J 1971 Production of peroxide in the thyroid. Canadian Medical Association 100 701-705.
5. Brasen JH, Leppanen O, Inkala M, Heikura T, Levin M, Ahrens F, Rutanen J, Pietsch H, Bergqvist D, Levonen AL et al. 2007 Extracellular superoxide dismutase accelerates endothelial recovery and inhibits in-stent restenosis in stented atherosclerotic Watanabe heritable hyperlipidemic rabbit aorta. Journal of the American College of Cardiology 50 2249-2253.
6. 2-generating system modulates protein iodination and the activity of the pentose phosphate pathway in dog thyroid. Endocrinology 128 779-785.
7. 2+ cascades in mediating the effects of thyrotropin and iodide on hormone synthesis and secretion in human thyroid slices. Journal of Clinical Endocrinology and Metabolism 79 152-159.
8. De Deken X, Wang D, Dumont JE & Miot F 2002 Characterization of ThOX proteins as components of the thyroid H(2)O(2)-generating system. Experimental Cell Research 273 187-196.
9. Dumont JE, Jauniaux JC & Roger PP 1989 The cyclic AMP-mediated stimulation of cell proliferation. Trends in Biochemical Sciences 14 67-71.
10. Dumont JE, Lamy F, Roger P & Maenhaut C 1992 Physiological and pathological regulation of thyroid cell proliferation and differentiation by thyrotropin and other factors. Physiological Reviews 72 667-697.
11. Duprez L, Parma J, Van Sande J, Allgeier A, Leclere J, Schvartz C, Delisle MJ, Decoulx M, Orgiazzi J, Dumont J et al. 1994 Germline mutations in the thyrotropin receptor gene cause non-autoimmune autosomal dominant hyperthyroidism. Nature Genetics 7 396-401.
12. Dupuy C, Virion A, Ohayon R, Kaniewski J, Deme D & Pommier J 1991 Mechanism of hydrogen peroxide formation catalyzed by NADPH oxidase in thyroid plasma membrane. Journal of Biological Chemistry 266 3739-3743. (Pubitemid 21909275)
13. Dupuy C, Pomerance M, Ohayon R, Noel-Hudson MS, Deme D, Chaaraoui M, Francon J & Virion A 2000 Thyroid oxidase (THOX2) gene expression in the rat thyroid cell line FRTL-5. Biochemical and Biophysical Research Communications 277 287-292.
14. Fusco A, Berlingieri MT, Di Fiore PP, Portella G, Grieco M & Vecchio G 1987 One- and two-step transformations of rat thyroid epithelial cells by retroviral oncogenes. Molecular Cell Biology 7 3365-3370.
15. 2. Role in cell survival following oxidant injury. Journal of Biological Chemistry 271 4138-4142.
16. Hatori N, Sjoquist PO, Marklund SL & Ryden L 1992 Effects of recombinant human extracellular-superoxide dismutase type C on myocardial infarct size in pigs. Free Radical Biology & Medicine 13 221-230.
17. Hebrant A, Van Sande J, Roger PP, Patey M, Klein M, Bournaud C, Savagner F, Leclere J, Dumont JE, van Staveren WC et al. 2009 Thyroid gene expression in familial nonautoimmune hyperthyroidism shows common characteristics with hyperfunctioning autonomous adenomas. Journal of Clinical Endocrinology and Metabolism 94 2602-2609.
18. Karlsson K & Marklund SL 1987 Heparin-induced release of extracellular superoxide dismutase to human blood plasma. Biochemical Journal 242 55-59. (Pubitemid 17015446)
19. Kogai T, Endo T, Saito T, Miyazaki A, Kawaguchi A & Onaya T 1997 Regulation by thyroid-stimulating hormone of sodium/iodide symporter gene expression and protein levels in FRTL-5 cells. Endocrinology 138 2227-2232. (Pubitemid 27215219)
20. Kondo T, Ezzat S & Asa SL 2006 Pathogenetic mechanisms in thyroid follicular-cell neoplasia. Nature Reviews. Cancer 6 292-306.
21. Konishi A, Aizawa T, Mohan A, Korshunov VA & Berk BC 2004 Hydrogen peroxide activates the Gas6-Axl pathway in vascular smooth muscle cells. Journal of Biological Chemistry 279 28766-28770. (Pubitemid 38900161)
22. Kuroki M, Voest EE, Amano S, Beerepoot LV, Takashima S, Tolentino M, Kim RY, Rohan RM, Colby KA, Yeo KT et al. 1996 Reactive oxygen intermediates increase vascular endothelial growth factor expression in vitro and in vivo. Journal of Clinical Investigation 98 1667-1675.
23. Laezza C, Mazziotti G, Fiorentino L, Gazzerro P, Portella G, Gerbasio D, Carella C, Matarese G & Bifulco M 2006 HMG-CoA reductase inhibitors inhibit rat propylthiouracil-induced goiter by modulating the ras-MAPK pathway. Journal of Molecular Medicine 84 967-973.
24. Laugwitz KL, Allgeier A, Offermanns S, Spicher K, Van Sande J, Dumont JE & Schultz G 1996 The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein families. PNAS 93 116-120.
25. Laukkanen MO, Lehtolainen P, Turunen P, Aittomaki S, Oikari P, Marklund SL & Yla-Herttuala S 2000 Rabbit extracellular superoxide dismutase: expression and effect on LDL oxidation. Gene 254 173-179.
26. Laukkanen MO, Leppanen P, Turunen P, Tuomisto T, Naarala J & Yla-Herttuala S 2001 EC-SOD gene therapy reduces paracetamol-induced liver damage in mice. Journal of Gene Medicine 3 321-325. (Pubitemid 33691771)
27. Laukkanen MO, Kivela A, Rissanen T, Rutanen J, Karkkainen MK, Leppanen O, Brasen JH & Yla-Herttuala S 2002 Adenovirus-mediated extracellular superoxide dismutase gene therapy reduces neointima formation in balloon-denuded rabbit aorta. Circulation 106 1999-2003. (Pubitemid 35176308)
28. Laurila JP, Castellone MD, Curcio A, Laatikainen LE, Haaparanta-Solin M, Gronroos TJ, Marjamaki P, Martikainen S, Santoro M & Laukkanen MO 2009 Extracellular superoxide dismutase is a growth regulatory mediator of tissue injury recovery. Molecular Therapy 17 448-454.
29. Levey HA 1963 Relationship of age to pituitary TSH levels and PTU-induced goitrogenesis in the rat. American Journal of Physiology 205 837-841.
30. Ludgate ME & Vassart G 1995 The thyrotropin receptor as a model to illustrate receptor and receptor antibody diseases. Bailliere's Clinical Endocrinology and Metabolism 9 95-113.
31. Maier J, van Steeg H, van Oostrom C, Paschke R, Weiss RE & Krohn K 2007 Iodine deficiency activates antioxidant genes and causes DNA damage in the thyroid gland of rats and mice. Biochimica et Biophysica Acta 1773 990-999.
32. Marklund SL 1984 Extracellular superoxide dismutase and other superoxide dismutase isoenzymes in tissues from nine mammalian species. Biochemical Journal 222 649-655.
33. 2-induced phosphorylation of ERK1/2 and PKB requires tyrosine kinase activity of insulin receptor and c-Src. Antioxidants & Redox Signaling 7 1014-1020.
34. Morand S, Ueyama T, Tsujibe S, Saito N, Korzeniowska A & Leto TL 2009 Duox maturation factors form cell surface complexes with Duox affecting the specificity of reactive oxygen species generation. FASEB Journal 23 1205-1218.
35. Moreno JC, Bikker H, Kempers MJ, van Trotsenburg AS, Baas F, de Vijlder JJ, Vulsma T & Ris-Stalpers C 2002 Inactivating mutations in the gene for thyroid oxidase 2 (THOX2) and congenital hypothyroidism. New England Journal of Medicine 347 95-102. (Pubitemid 34753479)
36. Pierce KL, Premont RT & Lefkowitz RJ 2002 Seven-transmembrane receptors. Nature Reviews. Molecular Cell Biology 3 639-650.
37. Rao GN 1997 Protein tyrosine kinase activity is required for oxidant-induced extracellular signal-regulated protein kinase activation and c-fos and c-jun expression. Cell Signalling 9 181-187.
38. Rao GN & Berk BC 1992 Active oxygen species stimulate vascular smooth muscle cell growth and proto-oncogene expression. Circulation Research 70 593-599.
39. Rigutto S, Hoste C, Dumont JE, Corvilain B, Miot F & De Deken X 2007 Duox1 is the main source of hydrogen peroxide in the rat thyroid cell line PCCl3. Experimental Cell Research 313 3892-3901. (Pubitemid 47566377)
40. Rybus-Kalinowska B, Zwirska-Korczala K, Kalinowski M, Kukla M, Birkner E & Jochem J 2008 Activity of antioxidative enzymes and concentration of malondialdehyde as oxidative status markers in women with newly diagnosed Graves-Basedow disease and after thiamazole therapy leading to euthyroidism. Polish Archives of Internal Medicine 118 420-425.
41. Saito S, Frank GD, Mifune M, Ohba M, Utsunomiya H, Motley ED, Inagami T & Eguchi S 2002 Ligand-independent trans-activation of the platelet-derived growth factor receptor by reactive oxygen species requires protein kinase C-delta and c-Src. Journal of Biological Chemistry 277 44695-44700.
42. Santoro M, Melillo RM, Grieco M, Berlingieri MT, Vecchio G & Fusco A 1993 The TRK and RET tyrosine kinase oncogenes cooperate with ras in the neoplastic transformation of a rat thyroid epithelial cell line. Cell Growth and Differentiation 4 77-84.
43. Sjoquist PO & Marklund SL 1992 Endothelium bound extracellular superoxide dismutase type C reduces damage in reperfused ischaemic rat hearts. Cardiovascular Research 26 347-350.
44. Song Y, Driessens N, Costa M, De Deken X, Detours V, Corvilain B, Maenhaut C, Miot F, Van Sande J, Many MC et al. 2007 Roles of hydrogen peroxide in thyroid physiology and disease. Journal of Clinical Endocrinology and Metabolism 92 3764-3773.
45. van Staveren WC, Solis DW, Delys L, Venet D, Cappello M, Andry G, Dumont JE, Libert F, Detours V & Maenhaut C 2006 Gene expression in human thyrocytes and autonomous adenomas reveals suppression of negative feedbacks in tumorigenesis. PNAS 103 413-418.
46. Wang X, McCullough KD, Franke TF & Holbrook NJ 2000 Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival. Journal of Biological Chemistry 275 14624-14631. (Pubitemid 30339753)
47. Wilson R, Chopra M, Bradley H, McKillop JH, Smith WE & Thomson JA 1989 Free radicals and Graves' disease: the effects of therapy. Clinical Endocrinology 30 429-433. (Pubitemid 19110016)
48. Zamproni I, Grasberger H, Cortinovis F, Vigone MC, Chiumello G, Mora S, Onigata K, Fugazzola L, Refetoff S, Persani L et al. 2008 Biallelic inactivation of the dual oxidase maturation factor 2 (DUOXA2) gene as a novel cause of congenital hypothyroidism. Journal of Clinical Endocrinology and Metabolism 93 605-610.