Anti-metastatic gene therapy utilizing subcutaneous inoculation of EC-SOD gene transduced autologous fibroblast suppressed lung metastasis of Meth-A cells and 3LL cells in mice

Gene Therapy

Volumn 8, Issue 2, 2001, Pages 149-156

  Tanaka, M ^a   Kogawa, K ^a   Nakamura, K ^a   Nishihori, Y ^a   Kuribayashi, K ^a   Hagiwara, S ^a   Muramatsu, H ^a   Sakamaki, S ^a   Niitsu, Y ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Autologous fibroblasts; Extracellular superoxide dismutase; Gene therapy; Metastasis; Retrovirus

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; ISOENZYME; SUPEROXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CELL MOTILITY; CONTROLLED STUDY; EMBRYO; ENZYME RELEASE; EXTRACELLULAR FLUID; FEMALE; FIBROBLAST; GENE THERAPY; GENETIC TRANSFECTION; HALF LIFE TIME; HUMAN; HUMAN TISSUE; INOCULATION; LUNG METASTASIS; MOUSE; NONHUMAN; PLASMA; PRIORITY JOURNAL; RETROVIRUS; TOXICITY; TUMOR CELL;

ANIMALS; CARCINOMA, LEWIS LUNG; CELL CULTURE TECHNIQUES; CELL DIVISION; CULTURE MEDIA; DNA, COMPLEMENTARY; FEASIBILITY STUDIES; FIBROBLASTS; GENE EXPRESSION; GENE THERAPY; ISOENZYMES; LUNG NEOPLASMS; MICE; MICE, INBRED BALB C; MICE, INBRED STRAINS; NEOPLASM TRANSPLANTATION; RNA, MESSENGER; SARCOMA, EXPERIMENTAL; SUPEROXIDE DISMUTASE; TRANSDUCTION, GENETIC;

ANIMALIA; RNA VIRUSES; UNIDENTIFIED RETROVIRUS;

EID: 0035138146     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301362     Document Type: Article

References (28)

1. Critical factors in the biology of human cancer metastasis. Twenty-eighth GHA Clowes memorial award lecture
2. Tumor invasion and metastases: Biochemical mechanisms
3. Metabolic suicide genes in gene therapy
4. Overexpression of manganese superoxide dismutase mRNA may correlate with aggressiveness in gastric and colorectal adenocarcinomas
5. MnSOD expression is increased in metastatic gastric cancer
6. Prognostic estimation of survival of colorectal cancer patients with the quantitative histochemical assay of G6PDH activity and the multiparameter classification program CLASSIF1
7. Production of superoxide by human malignant melanoma cells
8. Suppressive effect of recombinant human Cu, Zn-superoxide dismutase on lung metastasis of murine tumro cells
9. Sinusoidal endothelium release of hydrogen peroxide enhances very late antigen-4-mediated melanoma cell adherence and tumor cytotoxicity during interleukin-1 promotion of hepatic melanoma metastasis in mice
10. Experimental study on the role of osteoclasts and free radicals in the mandibular invasion of VX2 carcinoma in Japanese white rabbits
11. Superoxide dismutase in SAS human tongue carcinoma cell line is a factor defining invasiveness and cell motility
12. Suppression of intracellular Cu-Zn SOD results in enhanced motility and metastasis of Meth A sarcoma cells
13. Effect of lecithinized superoxide dismutase (PC-SOD) on experimental pulmonary metastasis in mice
14. Synthesis of a superoxide dismutase derivative that circulates bound to albumin and accumulates in tissues whose pH is decreased
15. Enhanced inhibition of experimental metastasis by the combination chemotherapy of Cu-Zn SOD and Adriamycin
16. Human copper-containing superoxide dismutase of high molecular weight
17. Plasma clearance of human extra-cellular-superoxide dismutase C in rabbits
18. Safety and plasma concentrations of bovine superoxide dismutase administered to human premature infants
19. Antimetastatic effects of synthetic polypeptides containing repeated structure of the cell adhesive Arg-Gly-Asp(RGD) and Tyr-Ile-Gly-Ser-Arg(YigSr) sequences
20. Intramuscular injection of expression plasmid DNA via an affective means of long-term systemic delivery of interleukin-5
21. Gene transduction for disseminated intraperitoneal tumor using cationic liposomes containing non-histone chromatin proteins: Cationic liposomal gene therapy of carcinomatosa
22. Efficient retrovirus-mediated cytokine-gene transduction of primary-cultured human glioma cells for tumor vaccination therapy
23. P53 tumor suppressor gene therapy for cancer
24. Immune and gene therapy for melanoma, and the immuno biology of melanoma
25. Gene therapy-future is here: A buide to the practicing urologist
26. Extracellular superoxide dismutase in the vascular system of mammals
27. Interactions between human extracellular superoxide dismutase C and sulfated polysaccharides
28. Vascular expression of extracellular dismutase in atherosclerosis