Protein interacting with C-kinase 1 (PICK1) binding promiscuity relies on unconventional PSD-95/discs-large/ZO-1 homology (PDZ) binding modes for nonclass II PDZ ligands

Journal of Biological Chemistry

Volumn 289, Issue 36, 2014, Pages 25327-25340

  Erlendsson, Simon ^a,b   Rathje, Mette ^a   Heidarsson, Pétur O ^b   Poulsen, Flemming M ^b   Madsen, Kenneth L ^a   Teilum, Kaare ^b   Gether, Ulrik ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; ENZYMES; ION EXCHANGE; LIGANDS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEINS;

DOPAMINE TRANSPORTERS; FLUORESCENT POLARIZATION; MULTIPLE CELLULAR FUNCTIONS; MUTATIONAL ANALYSIS; PROTEIN COMPLEXES; PROTEIN RECOGNITION; STRUCTURAL MECHANISMS; TERMINAL RESIDUES;

C (PROGRAMMING LANGUAGE);

PROTEIN INTERACTING WITH PROTEIN KINASE C; PROTEIN KINASE C ALPHA; CARRIER PROTEIN; LIGAND; NUCLEAR PROTEIN; PEPTIDE; PICK1 PROTEIN, HUMAN; PROTEIN BINDING;

ARTICLE; BINDING AFFINITY; HYDROGEN BOND; HYDROPHOBICITY; LIGAND BINDING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; AMINO ACID SEQUENCE; BINDING COMPETITION; BINDING SITE; CHEMISTRY; FLUORESCENCE POLARIZATION; GENETICS; HUMAN; METABOLISM; MOLECULAR DOCKING; MUTATION; PDZ DOMAIN; PROCEDURES;

AMINO ACID SEQUENCE; BINDING SITES; BINDING, COMPETITIVE; CARRIER PROTEINS; FLUORESCENCE POLARIZATION; HUMANS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR DOCKING SIMULATION; MUTATION; NUCLEAR PROTEINS; PDZ DOMAINS; PEPTIDES; PROTEIN BINDING; PROTEIN KINASE C-ALPHA;

EID: 84906987332     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.548743     Document Type: Article

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