Interaction of the synaptic protein PICK1 (protein interacting with C kinase 1) with the non-voltage gated sodium channels BNC1 (brain Na+ channel 1) and ASIC (acid-sensing ion channel)

Biochemical Journal

Volumn 361, Issue 3, 2002, Pages 443-450

  Hruska Hageman, Alesia M ^a   Wemmie, John A ^a   Price, Margaret P ^a   Welsh, Michael J ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

DEG ENaC channel; Mechanosensation; Mechanotransduction; Nociception; PDZ domain

Indexed keywords

BIOASSAY; BRAIN; CELLS; PH EFFECTS; POSITIVE IONS; SODIUM; YEAST;

MECHANOTRANSDUCTION;

ENZYMES;

CATION CHANNEL; ION CHANNEL; NERVE PROTEIN; PROTEIN INTERACTING WITH PROTEIN KINASE C; SODIUM CHANNEL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CENTRAL NERVOUS SYSTEM; DORSAL ROOT; GENE DELETION; HIPPOCAMPUS; MECHANORECEPTOR; NEMATODE; NOCICEPTION; NONHUMAN; PERIPHERAL NERVOUS SYSTEM; PH; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RAT; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; SYNAPSE; SYNAPTOSOME; TWO HYBRID SYSTEM;

ANIMALS; BINDING SITES; CARRIER PROTEINS; COLLAGEN; COS CELLS; DNA; DNA, COMPLEMENTARY; EPITHELIAL SODIUM CHANNEL; HIPPOCAMPUS; HYDROGEN-ION CONCENTRATION; ION CHANNELS; MEMBRANE PROTEINS; MICROSCOPY, FLUORESCENCE; MUTATION; NERVE TISSUE PROTEINS; NEURONS; NUCLEAR PROTEINS; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; SODIUM CHANNELS; TRANSFECTION; TWO-HYBRID SYSTEM TECHNIQUES;

ANIMALIA; MAMMALIA;

EID: 0036472120     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3610443     Document Type: Article

References (50)

1. + channel
2. The mammalian degenerin MDEG, an amiloride-sensitive cation channel activated by mutations causing neurodegeneration in Caenorhabditis elegans
3. BNaC1 and BNaC2 constitute a new family of human neuronal sodium channels related to degenerins and epithelial sodium channels
4. +-gated cation channels: Neuronal acid sensors in the NaC/DEG family of ion channels
5. A proton-gated cation channel involved in acid-sensing
6. + channel specific for sensory neurons
7. Molecular modeling of mechanotransduction in the nematode Caenorhabditis elegans
8. The mammalian sodium channel BNC1 is required for normal touch sensation
9. A modulatory subunit of acid sensing ion channels in brain and dorsal root ganglion cells
10. + channel 1 by inducing a conformational change that exposes a residue associated with neurodegeneration
11. Neuropeptide FF and FMRFamide potentiate acid-evoked currents from sensory neurons and proton-gated DEG/ENaC channels
12. Membrane topology of the amiloride-sensitive epithelial sodium channel
13. + channel
14. Membrane topology of the epithelial sodium channel in intact cells
15. Ion channel associated proteins
16. Organization and regulation of proteins at synapses
17. MEC-12, an α-tubulin required for touch sensitivity in C. elegans
18. mec-7 is a β-tubulin gene required for the production of 15-protofilament microtubules in Caenorhabditis elegans
19. A stomatin-like protein necessary for mechanosensation in C. elegans
20. Extracellular proteins needed for C. elegans mechanosensation
21. Interactions between subunits of the human epithelial sodium channel
22. Huntingtin-associated protein (HAP1): Discrete neuronal localizations in the brain resemble those of neuronal nitric oxide synthase
23. PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands
24. Viable cultured neurons in ambient carbon dioxide and hibernation storage for a month
25. Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination
26. Calcium influx via the NMDA receptor induces immediate early gene transcription by a MAP kinase/ERK-dependent mechanism
27. Specific interaction of the PDZ domain protein PICK1 with the COOH terminus of protein kinase C-α
28. Clustering of AMPA receptors by the synaptic PDZ domain-containing protein PICK1
29. The protein kinase C alpha binding protein PICK1 interacts with short but not long form alternative splice variants of AMPA receptor subunits
30. PICK1 interacts with and regulates PKC phosphorylation of mGLUR7
31. Presynaptic clustering of mGluR7a requires the PICK1 PDZ domain binding site
32. Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1
33. Crystal structure of a PDZ domain
34. Crystal structures of a complexed and peptide-free membrane protein- binding domain: Molecular basis of peptide recognition by PDZ
35. Recognition of unique carboxyl-terminal motifs by distinct PDZ domains
36. Rim is a putative Rab3 effector in regulating synaptic-vesicle fusion
37. Molecular determinants for PICK1 synaptic aggregation and mGluR7a receptor coclustering: Role of the PDZ, coiled coil, and acidic domains
38. Synaptic targeting of the postsynaptic density protein PSD-95 mediated by lipid and protein motifs
39. Translocation of the α- and β-isoforms of protein kinase C following activation of human T-lymphocytes
40. + exchanger regulatory factor family of PDZ proteins
41. A PDZ-interacting domain in CFTR is an apical membrane polarization signal
42. A sensory neuron-specific, proton-gated ion channel
43. + channel deleted in Liddle's syndrome
44. + channel by interaction of Nedd4 with a PY motif deleted in Liddle's syndrome
45. + channel (αrENaC) mediates its localization at the apical membrane
46. Regulation of the amiloride-sensitive epithelial sodium channel by syntaxin 1A
47. The molecules of mechanosensation
48. Transport and localization of the DEG/ENaC ion channel BNaC1α to peripheral mechanosensory terminals of dorsal root ganglia neurons
49. The cytoskeleton