PICK1 Deficiency Impairs Secretory Vesicle Biogenesis and Leads to Growth Retardation and Decreased Glucose Tolerance

PLoS Biology

Volumn 11, Issue 4, 2013, Pages

  Holst, Birgitte ^a,b   Madsen, Kenneth L ^b   Jansen, Anna M ^b   Jin, Chunyu ^a,b   Rickhag, Mattias ^b   Lund, Viktor K ^b   Jensen, Morten ^a,b   Bhatia, Vikram ^b   Sørensen, Gunnar ^b   Madsen, Andreas N ^a,b   Xue, Zhichao ^a,b   Møller, Siri K ^b   Woldbye, David ^b   Qvortrup, Klaus ^b   Huganir, Richard ^c   Stamou, Dimitrios ^b   Kjærulff, Ole ^b   Gether, Ulrik ^b  

^a Capital Region   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; INSULIN; MESSENGER RNA; PROTEIN ICA69; PROTEIN INTERACTING WITH PROTEIN KINASE C; SOMATOMEDIN C; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOGENESIS; BODY GROWTH; BODY HEIGHT; BODY WEIGHT; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DROSOPHILA; ELECTRON MICROSCOPY; FEMALE; GLUCOSE TOLERANCE; GROWTH HORMONE RELEASE; GROWTH RETARDATION; HYPOPHYSIS; IN VITRO STUDY; INSULIN RELEASE; LIPID DIET; LIPID STORAGE; MALE; MOUSE; NEUROSECRETORY CELL; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PROTEIN DEFICIENCY; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SECRETORY VESICLE; TRANS GOLGI NETWORK; UPREGULATION;

ANIMALS; AUTOANTIGENS; CARRIER PROTEINS; CELL LINE; CERCOPITHECUS AETHIOPS; COS CELLS; DROSOPHILA MELANOGASTER; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GLUCOSE; GLUCOSE INTOLERANCE; GROWTH DISORDERS; GROWTH HORMONE; HOMEOSTASIS; INSULIN; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NUCLEAR PROTEINS; PITUITARY GLAND; PROTEIN BINDING; PROTEIN TRANSPORT; RATS; SECRETORY VESICLES; TIME-LAPSE IMAGING; TRANS-GOLGI NETWORK;

MUS;

EID: 84876967040     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1001542     Document Type: Article

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