Nitrogen source activates TOR (Target of Rapamycin) complex 1 via glutamine and independently of Gtr/Rag proteins

Journal of Biological Chemistry

Volumn 289, Issue 36, 2014, Pages 25010-25020

  Stracka, Daniele ^a   Jozefczuk, Szymon ^b   Rudroff, Florian ^b   Sauer, Uwe ^b   Hall, Michael N ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CHEMICAL ACTIVATION; MAMMALS; PHOSPHORYLATION; YEAST;

COMPLEX 1; DIFFERENT MECHANISMS; GTPASES; NITROGEN SOURCES; ORTHOLOGS; TARGET OF RAPAMYCIN; TRANSIENT STIMULATION;

NITROGEN;

AMMONIA; GLUTAMINE; GUANOSINE TRIPHOSPHATASE; LEUCINE; NITROGEN; PEPTIDES AND PROTEINS; PHOSPHOTRANSFERASE; PROTEIN GTR; PROTEIN GTR1; PROTEIN RAG; PROTEIN SCH9; PROTEIN VAM6; TARGET OF RAPAMYCIN COMPLEX 1; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; AMMONIUM DERIVATIVE; GTR1 PROTEIN, S CEREVISIAE; GTR2 PROTEIN, S CEREVISIAE; METHIONINE SULFOXIMINE; MONOMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; PROLINE; PROTEIN SERINE THREONINE KINASE; RAPAMYCIN; SACCHAROMYCES CEREVISIAE PROTEIN; SCH9 PROTEIN, S CEREVISIAE; TORC1 PROTEIN COMPLEX, S CEREVISIAE;

ARTICLE; CELL GROWTH; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; FUNGAL CELL; FUNGAL METABOLISM; FUNGUS GROWTH; GROWTH RATE; NONHUMAN; NUTRIENT; SIGNAL TRANSDUCTION; YEAST; DRUG EFFECTS; GENETICS; GROWTH, DEVELOPMENT AND AGING; IMMUNOBLOTTING; METABOLISM; MUTATION; PHOSPHORYLATION; SACCHAROMYCES CEREVISIAE;

AMMONIUM COMPOUNDS; GLUTAMINE; IMMUNOBLOTTING; LEUCINE; METHIONINE SULFOXIMINE; MONOMERIC GTP-BINDING PROTEINS; MUTATION; NITROGEN; PHOSPHORYLATION; PROLINE; PROTEIN-SERINE-THREONINE KINASES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SIROLIMUS; TRANSCRIPTION FACTORS;

EID: 84906971940     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.574335     Document Type: Article

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