-
1
-
-
33847076849
-
Chromatin modifications and their function
-
Kouzarides T. 2007. Chromatin modifications and their function. Cell 128:693-705. http://dx.doi.org/10.1016/j.cell.2007.02.005.
-
(2007)
Cell
, vol.128
, pp. 693-705
-
-
Kouzarides, T.1
-
2
-
-
68249088114
-
Specific loss of histone H3 lysine 9 trimethylation and HP1gamma/cohesin binding at D4Z4 repeats is associated with facioscapulohumeral dystrophy (FSHD)
-
Zeng W, de Greef JC, Chen YY, Chien R, Kong X, Gregson HC, Winokur ST, Pyle A, Robertson KD, Schmiesing JA, Kimonis VE, Balog J, Frants RR, Ball AR, Jr, Lock LF, Donovan PJ, van der Maarel SM, Yokomori K. 2009. Specific loss of histone H3 lysine 9 trimethylation and HP1gamma/cohesin binding at D4Z4 repeats is associated with facioscapulohumeral dystrophy (FSHD). PLoS Genet. 5(7):e1000559. http://dx.doi.org/10.1371/journal.pgen.1000559.
-
(2009)
PLoS Genet.
, vol.5
, Issue.7
, pp. e1000559
-
-
Zeng, W.1
de Greef, J.C.2
Chen, Y.Y.3
Chien, R.4
Kong, X.5
Gregson, H.C.6
Winokur, S.T.7
Pyle, A.8
Robertson, K.D.9
Schmiesing, J.A.10
Kimonis, V.E.11
Balog, J.12
Frants, R.R.13
Ball Jr, A.R.14
Lock, L.F.15
Donovan, P.J.16
van der Maarel, S.M.17
Yokomori, K.18
-
3
-
-
84866115963
-
Telomere length regulates TERRA levels through increased trimethylation of telomeric H3K9 and HP1α
-
Arnoult N, Van Beneden A, Decottignies A. 2012. Telomere length regulates TERRA levels through increased trimethylation of telomeric H3K9 and HP1α. Nat. Struct. Mol. Biol. 19:948-956. http://dx.doi.org/10.1038/nsmb.2364.
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 948-956
-
-
Arnoult, N.1
Van Beneden, A.2
Decottignies, A.3
-
4
-
-
70949099119
-
Epigenetic silencing in Friedreich ataxia is associated with depletion of CTCF (CCCTC-Binding Factor) and antisense transcription
-
De Biase I, Chutake YK, Rindler PM, Bidichandani SI. 2009. Epigenetic silencing in Friedreich ataxia is associated with depletion of CTCF (CCCTC-Binding Factor) and antisense transcription. PLoS One 4(11): e7914. http://dx.doi.org/10.1371/journal.pone.0007914.
-
(2009)
PLoS One
, vol.4
, Issue.11
, pp. e7914
-
-
De Biase, I.1
Chutake, Y.K.2
Rindler, P.M.3
Bidichandani, S.I.4
-
5
-
-
66749172219
-
Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21
-
Derks S, Bosch LJ, Niessen HE, Moerkerk PT, van den Bosch SM, Carvalho B, Mongera S, Voncken JW, Meijer GA, de Brui¨ne AP, Herman JG, van Engeland M. 2009. Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21. Carcinogenesis 30:1041-1048. http://dx.doi.org/10.1093/carcin/bgp073.
-
(2009)
Carcinogenesis
, vol.30
, pp. 1041-1048
-
-
Derks, S.1
Bosch, L.J.2
Niessen, H.E.3
Moerkerk, P.T.4
van den Bosch, S.M.5
Carvalho, B.6
Mongera, S.7
Voncken, J.W.8
Meijer, G.A.9
de Brui¨ne, A.P.10
Herman, J.G.11
van Engeland, M.12
-
6
-
-
70350686180
-
SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state
-
Bilodeau S, Kagey MH, Frampton GM, Rahl PB, Young RA. 2009. SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state. Genes Dev. 23:2484-2489. http://dx.doi.org/10.1101/gad.1837309.
-
(2009)
Genes Dev.
, vol.23
, pp. 2484-2489
-
-
Bilodeau, S.1
Kagey, M.H.2
Frampton, G.M.3
Rahl, P.B.4
Young, R.A.5
-
7
-
-
77953809032
-
Distinct epigenomic landscapes of pluripotent and lineage- committed human cells
-
Hawkins RD, Hon GC, Lee LK, Ngo Q, Lister R, Pelizzola M, Edsall LE, Kuan S, Luu Y, Klugman S, Antosiewicz-Bourget J, Ye Z, Espinoza C, Agarwahl S, Shen L, Ruotti V, Wang W, Stewart R, Thomson JA, Ecker JR, Ren B. 2010. Distinct epigenomic landscapes of pluripotent and lineage- committed human cells. Cell Stem Cell 6:479-491. http://dx.doi.org/10.1016/j.stem.2010.03.018.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 479-491
-
-
Hawkins, R.D.1
Hon, G.C.2
Lee, L.K.3
Ngo, Q.4
Lister, R.5
Pelizzola, M.6
Edsall, L.E.7
Kuan, S.8
Luu, Y.9
Klugman, S.10
Antosiewicz-Bourget, J.11
Ye, Z.12
Espinoza, C.13
Agarwahl, S.14
Shen, L.15
Ruotti, V.16
Wang, W.17
Stewart, R.18
Thomson, J.A.19
Ecker, J.R.20
Ren, B.21
more..
-
8
-
-
84867009687
-
Asymmetrically modified nucleosomes
-
Voigt P, LeRoy G, Drury WJ, III, Zee BM, Son J, Beck DB, Young NL, Garcia BA, Reinberg D. 2012. Asymmetrically modified nucleosomes. Cell 151:181-193. http://dx.doi.org/10.1016/j.cell.2012.09.002.
-
(2012)
Cell
, vol.151
, pp. 181-193
-
-
Voigt, P.1
LeRoy, G.2
Drury III, W.J.3
Zee, B.M.4
Son, J.5
Beck, D.B.6
Young, N.L.7
Garcia, B.A.8
Reinberg, D.9
-
9
-
-
84864923697
-
Proteogenomic characterization and mapping of nucleosomes decoded by Brd and HP1 proteins
-
LeRoy G, Chepelev I, DiMaggio PA, Blanco MA, Zee BM, Zhao K, Garcia BA. 2012. Proteogenomic characterization and mapping of nucleosomes decoded by Brd and HP1 proteins. Genome Biol. 13:R68. http://dx.doi.org/10.1186/gb-2012-13-8-r68.
-
(2012)
Genome Biol.
, vol.13
, pp. R68
-
-
LeRoy, G.1
Chepelev, I.2
DiMaggio, P.A.3
Blanco, M.A.4
Zee, B.M.5
Zhao, K.6
Garcia, B.A.7
-
10
-
-
84892888891
-
Cdyl, a new partner of the inactive X chromosome and potential reader of H3K27me3 and H3K9me2
-
Escamilla-Del-Arenal M, da Rocha ST, Spruijt CG, Masui O, Renaud O, Smits AH, Margueron R, Vermeulen M, Heard E. 2013. Cdyl, a new partner of the inactive X chromosome and potential reader of H3K27me3 and H3K9me2. Mol. Cell. Biol. 33:5005-5020. http://dx.doi.org/10.1128/MCB.00866-13.
-
(2013)
Mol. Cell. Biol.
, vol.33
, pp. 5005-5020
-
-
Escamilla-Del-Arenal, M.1
da Rocha, S.T.2
Spruijt, C.G.3
Masui, O.4
Renaud, O.5
Smits, A.H.6
Margueron, R.7
Vermeulen, M.8
Heard, E.9
-
11
-
-
84892856196
-
The histone H3 lysine 9 methyltransferases G9a and GLP regulate polycomb repressive complex 2-mediated gene silencing
-
Mozzetta C, Pontis J, Fritsch L, Robin P, Portoso M, Proux C, Margueron R, Ait-Si-Ali S. 2014. The histone H3 lysine 9 methyltransferases G9a and GLP regulate polycomb repressive complex 2-mediated gene silencing. Mol. Cell 53:277-289. http://dx.doi.org/10.1016/j.molcel.2013.12.005.
-
(2014)
Mol. Cell
, vol.53
, pp. 277-289
-
-
Mozzetta, C.1
Pontis, J.2
Fritsch, L.3
Robin, P.4
Portoso, M.5
Proux, C.6
Margueron, R.7
Ait-Si-Ali, S.8
-
12
-
-
0034632829
-
Regulation of chromatin structure by site-specific histone H3 methyltransferases
-
Rea S, Eisenhaber F, O'Carroll D, Strahl BD, Sun ZW, Schmid M, Opravil S, Mechtler K, Ponting CP, Allis CD, Jenuwein T. 2000. Regulation of chromatin structure by site-specific histone H3 methyltransferases. Nature 406:593-599. http://dx.doi.org/10.1038/35020506.
-
(2000)
Nature
, vol.406
, pp. 593-599
-
-
Rea, S.1
Eisenhaber, F.2
O'Carroll, D.3
Strahl, B.D.4
Sun, Z.W.5
Schmid, M.6
Opravil, S.7
Mechtler, K.8
Ponting, C.P.9
Allis, C.D.10
Jenuwein, T.11
-
13
-
-
78751662908
-
The Polycomb complex PRC2 and its mark in life
-
Margueron R, Reinberg D. 2011. The Polycomb complex PRC2 and its mark in life. Nature 469:343-349. http://dx.doi.org/10.1038/nature09784.
-
(2011)
Nature
, vol.469
, pp. 343-349
-
-
Margueron, R.1
Reinberg, D.2
-
14
-
-
55549103314
-
A model for transmission of the H3K27me3 epigenetic mark
-
Hansen KH, Bracken AP, Pasini D, Dietrich N, Gehani SS, Monrad A, Rappsilber J, Lerdrup M, Helin K. 2008. A model for transmission of the H3K27me3 epigenetic mark. Nat. Cell Biol. 10:1291-1300. http://dx.doi.org/10.1038/ncb1787.
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 1291-1300
-
-
Hansen, K.H.1
Bracken, A.P.2
Pasini, D.3
Dietrich, N.4
Gehani, S.S.5
Monrad, A.6
Rappsilber, J.7
Lerdrup, M.8
Helin, K.9
-
15
-
-
70349952171
-
Role of the polycomb protein EED in the propagation of repressive histone marks
-
Margueron R, Justin N, Ohno K, Sharpe ML, Son J, Drury WJ, III, Voigt P, Martin SR, Taylor WR, De Marco V, Pirrotta V, Reinberg D, Gamblin SJ. 2009. Role of the polycomb protein EED in the propagation of repressive histone marks. Nature 461:762-767. http://dx.doi.org/10.1038/nature08398.
-
(2009)
Nature
, vol.461
, pp. 762-767
-
-
Margueron, R.1
Justin, N.2
Ohno, K.3
Sharpe, M.L.4
Son, J.5
Drury III, W.J.6
Voigt, P.7
Martin, S.R.8
Taylor, W.R.9
De Marco, V.10
Pirrotta, V.11
Reinberg, D.12
Gamblin, S.J.13
-
16
-
-
0035282458
-
Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain
-
Bannister AJ, Zegerman P, Partridge JF, Miska EA, Thomas JO, Allshire RC, Kouzarides T. 2001. Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature 410:120-124. http://dx.doi.org/10.1038/35065138.
-
(2001)
Nature
, vol.410
, pp. 120-124
-
-
Bannister, A.J.1
Zegerman, P.2
Partridge, J.F.3
Miska, E.A.4
Thomas, J.O.5
Allshire, R.C.6
Kouzarides, T.7
-
17
-
-
0035282573
-
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
-
Lachner M, O'Carroll D, Rea SR, Mechtler K, Jenuwein T. 2001. Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature 410:116-120. http://dx.doi.org/10.1038/35065132.
-
(2001)
Nature
, vol.410
, pp. 116-120
-
-
Lachner, M.1
O'Carroll, D.2
Rea, S.R.3
Mechtler, K.4
Jenuwein, T.5
-
18
-
-
0035815360
-
Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly
-
Nakayama J, Rice JC, Strahl BD, Allis CD, Grewal SI. 2001. Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly. Science 292:110-113. http://dx.doi.org/10.1126/science.1060118.
-
(2001)
Science
, vol.292
, pp. 110-113
-
-
Nakayama, J.1
Rice, J.C.2
Strahl, B.D.3
Allis, C.D.4
Grewal, S.I.5
-
19
-
-
1842733449
-
HP1 and the dynamics of heterochromatin maintenance
-
Maison C, Almouzni G. 2004. HP1 and the dynamics of heterochromatin maintenance. Nat. Rev. Mol. Cell Biol. 5:296-304. http://dx.doi.org/10.1038/nrm1355.
-
(2004)
Nat. Rev. Mol. Cell Biol.
, vol.5
, pp. 296-304
-
-
Maison, C.1
Almouzni, G.2
-
20
-
-
0037086355
-
Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail
-
Jacobs SA, Khorasanizadeh S. 2002. Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail. Science 295:2080-2083. http://dx.doi.org/10.1126/science.1069473.
-
(2002)
Science
, vol.295
, pp. 2080-2083
-
-
Jacobs, S.A.1
Khorasanizadeh, S.2
-
21
-
-
0037034911
-
Structure of the HP1 chromodomain bound to histone H3 methylated at lysine 9
-
Nielsen PR, Nietlispach D, Mott HR, Callaghan J, Bannister A, Kouzarides T, Murzin AG, Murzina NV, Laue ED. 2002. Structure of the HP1 chromodomain bound to histone H3 methylated at lysine 9. Nature 416:103-107. http://dx.doi.org/10.1038/nature722.
-
(2002)
Nature
, vol.416
, pp. 103-107
-
-
Nielsen, P.R.1
Nietlispach, D.2
Mott, H.R.3
Callaghan, J.4
Bannister, A.5
Kouzarides, T.6
Murzin, A.G.7
Murzina, N.V.8
Laue, E.D.9
-
22
-
-
0032215539
-
The heterochromatin protein 1 prevents telomere fusions in Drosophila.
-
Fanti L, Giovinazzo G, Berloco M, Pimpinelli S. 1998. The heterochromatin protein 1 prevents telomere fusions in Drosophila. Mol. Cell 2:527-538. http://dx.doi.org/10.1016/S1097-2765(00)80152-5.
-
(1998)
Mol. Cell
, vol.2
, pp. 527-538
-
-
Fanti, L.1
Giovinazzo, G.2
Berloco, M.3
Pimpinelli, S.4
-
23
-
-
57349135362
-
Balance between distinct HP1 family proteins controls heterochromatin assembly in fission yeast
-
Sadaie M, Kawaguchi R, Ohtani Y, Arisaka F, Tanaka K, Shirahige K, Nakayama J. 2008. Balance between distinct HP1 family proteins controls heterochromatin assembly in fission yeast. Mol. Cell. Biol. 28:6973-6988. http://dx.doi.org/10.1128/MCB.00791-08.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 6973-6988
-
-
Sadaie, M.1
Kawaguchi, R.2
Ohtani, Y.3
Arisaka, F.4
Tanaka, K.5
Shirahige, K.6
Nakayama, J.7
-
24
-
-
33846130043
-
HP1 binding to chromatin methylated at H3K9 is enhanced by auxiliary factors
-
Eskeland R, Eberharter A, Imhof A. 2007. HP1 binding to chromatin methylated at H3K9 is enhanced by auxiliary factors. Mol. Cell. Biol. 27: 453-465. http://dx.doi.org/10.1128/MCB.01576-06.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 453-465
-
-
Eskeland, R.1
Eberharter, A.2
Imhof, A.3
-
25
-
-
0037089626
-
SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromaic genes by KRAB zinc-finger proteins
-
Schultz DC, Ayyanathan K, Negorev D, Maul GG, Rauscher 3rd, FJ. 2002. SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromaic genes by KRAB zinc-finger proteins. Genes Dev. 16:919-932. http://dx.doi.org/10.1101/gad.973302.
-
(2002)
Genes Dev.
, vol.16
, pp. 919-932
-
-
Schultz, D.C.1
Ayyanathan, K.2
Negorev, D.3
Maul, G.G.4
Rauscher III, F.J.5
-
26
-
-
0347683447
-
Polycomb group suppressor of zeste 12 links heterochromatin protein 1alpha and enhancer of zeste 2
-
Yamamoto K, Sonoda M, Inokuchi J, Shirasawa S, Sasazuki T. 2004. Polycomb group suppressor of zeste 12 links heterochromatin protein 1alpha and enhancer of zeste 2. J. Biol. Chem. 279:401-406. http://dx.doi.org/10.1074/jbc.M307344200.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 401-406
-
-
Yamamoto, K.1
Sonoda, M.2
Inokuchi, J.3
Shirasawa, S.4
Sasazuki, T.5
-
27
-
-
34248171732
-
The polycomb group protein SUZ12 regulates histone H3 lysine 9 methylation and HP1 alpha distribution
-
de la Cruz CC, Kirmizis A, Simon MD, Isono K, Koseki H, Panning B. 2007. The polycomb group protein SUZ12 regulates histone H3 lysine 9 methylation and HP1 alpha distribution. Chromosome Res. 15:299-314. http://dx.doi.org/10.1007/s10577-007-1126-1.
-
(2007)
Chromosome Res.
, vol.15
, pp. 299-314
-
-
de la Cruz, C.C.1
Kirmizis, A.2
Simon, M.D.3
Isono, K.4
Koseki, H.5
Panning, B.6
-
28
-
-
77956643239
-
Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers
-
Vermeulen M, Eberl HC, Matarese F, Marks H, Denissov S, Butter F, Lee KK, Olsen JV, Hyman AA, Stunnenberg HG, Mann M. 2010. Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers. Cell 142:967-980. http://dx.doi.org/10.1016/j.cell.2010.08.020.
-
(2010)
Cell
, vol.142
, pp. 967-980
-
-
Vermeulen, M.1
Eberl, H.C.2
Matarese, F.3
Marks, H.4
Denissov, S.5
Butter, F.6
Lee, K.K.7
Olsen, J.V.8
Hyman, A.A.9
Stunnenberg, H.G.10
Mann, M.11
-
29
-
-
84872762027
-
A map of general and specialized chromatin readers in mouse tissues generated by label-free interaction proteomics
-
Eberl HC, Spruijt CG, Kelstrup CD, Vermeulen M, Mann M. 2013. A map of general and specialized chromatin readers in mouse tissues generated by label-free interaction proteomics. Mol. Cell 49:368-378. http://dx.doi.org/10.1016/j.molcel.2012.10.026.
-
(2013)
Mol. Cell
, vol.49
, pp. 368-378
-
-
Eberl, H.C.1
Spruijt, C.G.2
Kelstrup, C.D.3
Vermeulen, M.4
Mann, M.5
-
30
-
-
0142105414
-
EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer
-
Bracken AP, Pasini D, Capra M, Prosperini E, Colli E, Helin K. 2003. EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer. EMBO J. 22:5323-5335. http://dx.doi.org/10.1093/emboj/cdg542.
-
(2003)
EMBO J.
, vol.22
, pp. 5323-5335
-
-
Bracken, A.P.1
Pasini, D.2
Capra, M.3
Prosperini, E.4
Colli, E.5
Helin, K.6
-
31
-
-
77950866779
-
Polycomb protein EZH2 regulates E2F1-dependent apoptosis through epigenetically modulating Bim expression
-
Wu ZL, Zheng SS, Li ZM, Qiao YY, Aau MY, Yu Q. 2010. Polycomb protein EZH2 regulates E2F1-dependent apoptosis through epigenetically modulating Bim expression. Cell Death Differ. 17:801-810. http://dx.doi.org/10.1038/cdd.2009.162.
-
(2010)
Cell Death Differ.
, vol.17
, pp. 801-810
-
-
Wu, Z.L.1
Zheng, S.S.2
Li, Z.M.3
Qiao, Y.Y.4
Aau, M.Y.5
Yu, Q.6
-
32
-
-
33846225576
-
Histone deacetylase inhibitors deplete enhancer of zeste 2 and associated polycomb repressive complex 2 proteins in human acute leukemia cells
-
Fiskus W, Pranpat M, Balasis M, Herger B, Rao R, Chinnaiyan A, Atadja P, Bhalla K. 2006. Histone deacetylase inhibitors deplete enhancer of zeste 2 and associated polycomb repressive complex 2 proteins in human acute leukemia cells. Mol. Cancer Ther. 5:3096-3104. http://dx.doi.org/10.1158/1535-7163.MCT-06-0418.
-
(2006)
Mol. Cancer Ther.
, vol.5
, pp. 3096-3104
-
-
Fiskus, W.1
Pranpat, M.2
Balasis, M.3
Herger, B.4
Rao, R.5
Chinnaiyan, A.6
Atadja, P.7
Bhalla, K.8
-
33
-
-
0037197845
-
Isoform-specific interaction of HP1 with human TAFII130
-
Vassallo MF, Tanese N. 2002. Isoform-specific interaction of HP1 with human TAFII130. Proc. Natl. Acad. Sci. U. S. A. 99:5919-5924. http://dx.doi.org/10.1073/pnas.092025499.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 5919-5924
-
-
Vassallo, M.F.1
Tanese, N.2
-
34
-
-
35148867907
-
UTX and JMJD3 are H3K27 demethylases involved in HOX gene regulation and development
-
Agger K, Cloos PA, Christensen J, Pasini D, Rose S, Rappsilber J, Issaeva I, Canaani E, Salcini AE, Helin K. 2007. UTX and JMJD3 are H3K27 demethylases involved in HOX gene regulation and development. Nature 449:731-734. http://dx.doi.org/10.1038/nature06145.
-
(2007)
Nature
, vol.449
, pp. 731-734
-
-
Agger, K.1
Cloos, P.A.2
Christensen, J.3
Pasini, D.4
Rose, S.5
Rappsilber, J.6
Issaeva, I.7
Canaani, E.8
Salcini, A.E.9
Helin, K.10
-
36
-
-
0032519809
-
Stage-specific expression of polycomb group genes in human bone marrow cells
-
Lessard J, Baban S, Sauvageau G. 1998. Stage-specific expression of polycomb group genes in human bone marrow cells. Blood 91:1216- 1224.
-
(1998)
Blood
, vol.91
, pp. 1216- 1224
-
-
Lessard, J.1
Baban, S.2
Sauvageau, G.3
-
37
-
-
21844440558
-
PIASx acts as an Elk-1 coactivator by facilitating derepression
-
Yang SH, Sharrocks AD. 2005. PIASx acts as an Elk-1 coactivator by facilitating derepression. EMBO J. 24:2161-2171. http://dx.doi.org/10.1038/sj.emboj.7600690.
-
(2005)
EMBO J.
, vol.24
, pp. 2161-2171
-
-
Yang, S.H.1
Sharrocks, A.D.2
-
38
-
-
18644382388
-
The polycomb group protein EZH2 is involved in progression of prostate cancer
-
Varambally S, Dhanasekaran SM, Zhou M, Barrette TR, Kumar-Sinha C, Sanda MG, Ghosh D, Pienta KJ, Sewalt RG, Otte AP, Rubin MA, Chinnaiyan AM. 2002. The polycomb group protein EZH2 is involved in progression of prostate cancer. Nature 419:624-629. http://dx.doi.org/10.1038/nature01075.
-
(2002)
Nature
, vol.419
, pp. 624-629
-
-
Varambally, S.1
Dhanasekaran, S.M.2
Zhou, M.3
Barrette, T.R.4
Kumar-Sinha, C.5
Sanda, M.G.6
Ghosh, D.7
Pienta, K.J.8
Sewalt, R.G.9
Otte, A.P.10
Rubin, M.A.11
Chinnaiyan, A.M.12
-
39
-
-
60149096212
-
Downregulation of EZH2 decreases growth of estrogen receptor-negative invasive breast carcinoma and requires BRCA1
-
Gonzalez ME, Li X, Toy K, DuPrie M, Ventura AC, Banerjee M, Ljungman M, Merajver SD, Kleer CG. 2009. Downregulation of EZH2 decreases growth of estrogen receptor-negative invasive breast carcinoma and requires BRCA1. Oncogene 28:843-853. http://dx.doi.org/10.1038/onc.2008.433.
-
(2009)
Oncogene
, vol.28
, pp. 843-853
-
-
Gonzalez, M.E.1
Li, X.2
Toy, K.3
DuPrie, M.4
Ventura, A.C.5
Banerjee, M.6
Ljungman, M.7
Merajver, S.D.8
Kleer, C.G.9
-
40
-
-
79960266611
-
EZH2 depletion blocks the proliferation of colon cancer cells
-
Fussbroich B, Wagener N, Macher-Goeppinger S, Benner A, Fa¨lth M, Su¨ltmann H, Holzer A, Hoppe-Seyler K, Hoppe-Seyler F. 2011. EZH2 depletion blocks the proliferation of colon cancer cells. PLoS One 6(7): e21651. http://dx.doi.org/10.1371/journal.pone.0021651.
-
(2011)
PLoS One
, vol.6
, Issue.7
, pp. e21651
-
-
Fussbroich, B.1
Wagener, N.2
Macher-Goeppinger, S.3
Benner, A.4
Fa¨lth, M.5
Su¨ltmann, H.6
Holzer, A.7
Hoppe-Seyler, K.8
Hoppe-Seyler, F.9
-
41
-
-
28844477653
-
Regulation of HP1- chromatin binding by histone H3 methylation and phosphorylation
-
Fischle W, Tseng BS, Dormann HL, Ueberheide BM, Garcia BA, Shabanowitz J, Hunt DF, Funabiki H, Allis CD. 2005. Regulation of HP1- chromatin binding by histone H3 methylation and phosphorylation. Nature 438:1116-1122. http://dx.doi.org/10.1038/nature04219.
-
(2005)
Nature
, vol.438
, pp. 1116-1122
-
-
Fischle, W.1
Tseng, B.S.2
Dormann, H.L.3
Ueberheide, B.M.4
Garcia, B.A.5
Shabanowitz, J.6
Hunt, D.F.7
Funabiki, H.8
Allis, C.D.9
-
42
-
-
77956278711
-
Lamin A rod mutants target heterochromatin protein 1alpha and beta for proteasomal degradation by activation of F-box protein, FBXW10
-
Chaturvedi P, Parnaik VK. 2010. Lamin A rod mutants target heterochromatin protein 1alpha and beta for proteasomal degradation by activation of F-box protein, FBXW10. PLoS One 5(5):e10620. http://dx.doi.org/10.1371/journal.pone.0010620.
-
(2010)
PLoS One
, vol.5
, Issue.5
, pp. e10620
-
-
Chaturvedi, P.1
Parnaik, V.K.2
-
43
-
-
84867512138
-
Ubiquitin ligase RNF123 mediates degradation of heterochromatin protein 1a and b in lamin A/C knock-down cells
-
Chaturvedi P, Khanna R, Parnaik VK. 2012. Ubiquitin ligase RNF123 mediates degradation of heterochromatin protein 1a and b in lamin A/C knock-down cells. PLoS One 7(10):e47558. http://dx.doi.org/10.1371/journal.pone.0047558.
-
(2012)
PLoS One
, vol.7
, Issue.10
, pp. e47558
-
-
Chaturvedi, P.1
Khanna, R.2
Parnaik, V.K.3
-
44
-
-
3042801308
-
SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex
-
Cao R, Zhang Y. 2004. SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex. Mol. Cell 15:57-67. http://dx.doi.org/10.1016/j.molcel.2004.06.020.
-
(2004)
Mol. Cell
, vol.15
, pp. 57-67
-
-
Cao, R.1
Zhang, Y.2
-
45
-
-
8144230178
-
Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity
-
Pasini D, Bracken AP, Jensen MR, Lazzerini Denchi E, Helin K. 2004. Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity. EMBO J. 23:4061-4071. http://dx.doi.org/10.1038/sj.emboj.7600402.
-
(2004)
EMBO J.
, vol.23
, pp. 4061-4071
-
-
Pasini, D.1
Bracken, A.P.2
Jensen, M.R.3
Lazzerini Denchi, E.4
Helin, K.5
-
46
-
-
0043127085
-
Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains
-
Fischle W, Wang Y, Jacobs SA, Kim Y, Allis CD, Khorasanizadeh S. 2003. Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains. Genes Dev. 17:1870-1881. http://dx.doi.org/10.1101/gad.1110503.
-
(2003)
Genes Dev.
, vol.17
, pp. 1870-1881
-
-
Fischle, W.1
Wang, Y.2
Jacobs, S.A.3
Kim, Y.4
Allis, C.D.5
Khorasanizadeh, S.6
-
47
-
-
0034599522
-
The structure of mouse HP1 suggests a unique mode of single peptide recognition by the shadow chromo domain dimer
-
Brasher SV, Smith BO, Fogh RH, Nietlispach D, Thiru A, Nielsen PR, Broadhurst RW, Ball LJ, Murzina NV, Laue ED. 2000. The structure of mouse HP1 suggests a unique mode of single peptide recognition by the shadow chromo domain dimer. EMBO J. 19:1587-1597. http://dx.doi.org/10.1093/emboj/19.7.1587.
-
(2000)
EMBO J.
, vol.19
, pp. 1587-1597
-
-
Brasher, S.V.1
Smith, B.O.2
Fogh, R.H.3
Nietlispach, D.4
Thiru, A.5
Nielsen, P.R.6
Broadhurst, R.W.7
Ball, L.J.8
Murzina, N.V.9
Laue, E.D.10
-
48
-
-
0035019466
-
Heterochromatin formation in mammalian cells: interaction between histones and HP1 proteins
-
Nielsen AL, Oulad-Abdelghani M, Ortiz JA, Remboutsika E, Chambon P, Losson R. 2001. Heterochromatin formation in mammalian cells: interaction between histones and HP1 proteins. Mol. Cell 7:729-739. http://dx.doi.org/10.1016/S1097-2765(01)00218-0.
-
(2001)
Mol. Cell
, vol.7
, pp. 729-739
-
-
Nielsen, A.L.1
Oulad-Abdelghani, M.2
Ortiz, J.A.3
Remboutsika, E.4
Chambon, P.5
Losson, R.6
-
49
-
-
23044431656
-
Histone H3 lysine 9 methylation and HP1γ are associated with transcription elongation through mammalian chromatin
-
Vakoc CR, Mandat SA, Olenchock BA, Blobel GA. 2005. Histone H3 lysine 9 methylation and HP1γ are associated with transcription elongation through mammalian chromatin. Mol. Cell 19:381-391. http://dx.doi.org/10.1016/j.molcel.2005.06.011.
-
(2005)
Mol. Cell
, vol.19
, pp. 381-391
-
-
Vakoc, C.R.1
Mandat, S.A.2
Olenchock, B.A.3
Blobel, G.A.4
-
50
-
-
79952704960
-
The changing faces of HP1: from heterochromatin formation and gene silencing to euchromatic gene expression
-
Kwon SH, Workman JL. 2011. The changing faces of HP1: from heterochromatin formation and gene silencing to euchromatic gene expression. Bioessays 33:280-289. http://dx.doi.org/10.1002/bies.201000138.
-
(2011)
Bioessays
, vol.33
, pp. 280-289
-
-
Kwon, S.H.1
Workman, J.L.2
-
51
-
-
84862560519
-
Polycomb protein EZH2 regulates tumor invasion via the transcriptional repression of the metastasis suppressor RKIP in breast and prostate cancer
-
Ren G, Baritaki S, Marathe H, Feng J, Park S, Beach S, Bazeley PS, Beshir AB, Fenteany G, Mehra R, Daignault S, Al-Mulla F, Keller E, Bonavida B, de la Serna I, Yeung KC. 2012. Polycomb protein EZH2 regulates tumor invasion via the transcriptional repression of the metastasis suppressor RKIP in breast and prostate cancer. Cancer Res. 72:3091- 3104. http://dx.doi.org/10.1158/0008-5472.CAN-11-3546.
-
(2012)
Cancer Res.
, vol.72
, pp. 3091- 3104
-
-
Ren, G.1
Baritaki, S.2
Marathe, H.3
Feng, J.4
Park, S.5
Beach, S.6
Bazeley, P.S.7
Beshir, A.B.8
Fenteany, G.9
Mehra, R.10
Daignault, S.11
Al-Mulla, F.12
Keller, E.13
Bonavida, B.14
de la Serna, I.15
Yeung, K.C.16
-
52
-
-
78650734995
-
Chromodomain-mediated oligomerization of HP1 suggests a nucleosome-bridging mechanism for heterochromatin assembly
-
Canzio D, Chang EY, Shankar S, Kuchenbecker KM, Simon MD, Madhani HD, Narlikar GJ, Al-Sady B. 2011. Chromodomain-mediated oligomerization of HP1 suggests a nucleosome-bridging mechanism for heterochromatin assembly. Mol. Cell 41:67-81. http://dx.doi.org/10.1016/j.molcel.2010.12.016.
-
(2011)
Mol. Cell
, vol.41
, pp. 67-81
-
-
Canzio, D.1
Chang, E.Y.2
Shankar, S.3
Kuchenbecker, K.M.4
Simon, M.D.5
Madhani, H.D.6
Narlikar, G.J.7
Al-Sady, B.8
-
53
-
-
77954818442
-
Genome-nuclear lamina interactions and gene regulation
-
Kind J, van Steensel B. 2010. Genome-nuclear lamina interactions and gene regulation. Curr. Opin. Cell Biol. 22:320-325. http://dx.doi.org/10.1016/j.ceb.2010.04.002.
-
(2010)
Curr. Opin. Cell Biol.
, vol.22
, pp. 320-325
-
-
Kind, J.1
van Steensel, B.2
-
54
-
-
0030987777
-
Domain-specific interactions of human HP1-type chromodomain proteins and inner nuclear membrane protein LBR
-
Ye Q, Callebaut I, Pezhman A, Courvalin JC, Howard J, Worman HJ. 1997. Domain-specific interactions of human HP1-type chromodomain proteins and inner nuclear membrane protein LBR. J. Biol. Chem. 272: 14983-14989. http://dx.doi.org/10.1074/jbc.272.23.14983.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 14983-14989
-
-
Ye, Q.1
Callebaut, I.2
Pezhman, A.3
Courvalin, J.C.4
Howard, J.5
Worman, H.J.6
-
55
-
-
30044435641
-
Histone lysine methylation patterns in human cell types are arranged in distinct three-dimensional nuclear zones
-
Zinner R, Albiez H, Walter J, Peters AH, Cremer T, Cremer M. 2006. Histone lysine methylation patterns in human cell types are arranged in distinct three-dimensional nuclear zones. Histochem. Cell Biol. 125:3-19. http://dx.doi.org/10.1007/s00418-005-0049-1.
-
(2006)
Histochem. Cell Biol.
, vol.125
, pp. 3-19
-
-
Zinner, R.1
Albiez, H.2
Walter, J.3
Peters, A.H.4
Cremer, T.5
Cremer, M.6
-
56
-
-
33745016642
-
Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging
-
Shumaker DK, Dechat T, Kohlmaier A, Adam SA, Bozovsky MR, Erdos MR, Eriksson MR, Goldman AE, Khuon S, Collins FS, Jenuwein T, Goldman RD. 2006. Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging. Proc. Natl. Acad. Sci. U. S. A. 103:8703-8708. http://dx.doi.org/10.1073/pnas.0602569103.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 8703-8708
-
-
Shumaker, D.K.1
Dechat, T.2
Kohlmaier, A.3
Adam, S.A.4
Bozovsky, M.R.5
Erdos, M.R.6
Eriksson, M.R.7
Goldman, A.E.8
Khuon, S.9
Collins, F.S.10
Jenuwein, T.11
Goldman, R.D.12
-
57
-
-
66449126030
-
Nuclear lamins and chromatin: when structure meets function
-
Dechat T, Adam SA, Goldman RD. 2009. Nuclear lamins and chromatin: when structure meets function. Adv. Enzyme Regul. 49:157-166. http://dx.doi.org/10.1016/j.advenzreg.2008.12.003.
-
(2009)
Adv. Enzyme Regul.
, vol.49
, pp. 157-166
-
-
Dechat, T.1
Adam, S.A.2
Goldman, R.D.3
-
58
-
-
72149127696
-
Heterochromatin protein 1 is extensively decorated with histone code-like post-translational modifications
-
LeRoy G, Weston JT, Zee BM, Young NL, Plazas-Mayorca MD, Garcia BA. 2009. Heterochromatin protein 1 is extensively decorated with histone code-like post-translational modifications. Mol. Cell. Proteomics 8:2432-2442. http://dx.doi.org/10.1074/mcp.M900160-MCP200.
-
(2009)
Mol. Cell. Proteomics
, vol.8
, pp. 2432-2442
-
-
LeRoy, G.1
Weston, J.T.2
Zee, B.M.3
Young, N.L.4
Plazas-Mayorca, M.D.5
Garcia, B.A.6
-
59
-
-
33750379420
-
Polycomb silencers control cell fate, development and cancer
-
Sparmann A, van Lohuizen M. 2006. Polycomb silencers control cell fate, development and cancer. Nat. Rev. Cancer 6:846-856. http://dx.doi.org/10.1038/nrc1991.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 846-856
-
-
Sparmann, A.1
van Lohuizen, M.2
-
60
-
-
0038412822
-
The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase
-
Fuks F, Hurd PJ, Deplus R, Kouzarides T. 2003. The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase. Nucleic Acids Res. 31:2305-2312. http://dx.doi.org/10.1093/nar/gkg332.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 2305-2312
-
-
Fuks, F.1
Hurd, P.J.2
Deplus, R.3
Kouzarides, T.4
-
61
-
-
82755160671
-
Epigenetic alterations associated with cellular senescence: a barrier against tumorigenesis or a red carpet for cancer?
-
Decottignies A, d'Adda di Fagagna F. 2011. Epigenetic alterations associated with cellular senescence: a barrier against tumorigenesis or a red carpet for cancer? Semin. Cancer Biol. 21:360-366. http://dx.doi.org/10.1016/j.semcancer.2011.09.003.
-
(2011)
Semin. Cancer Biol.
, vol.21
, pp. 360-366
-
-
Decottignies, A.1
d'Adda di Fagagna, F.2
|