Epigenetic alterations associated with cellular senescence: A barrier against tumorigenesis or a red carpet for cancer?

Seminars in Cancer Biology

Volumn 21, Issue 6, 2011, Pages 360-366

  Decottignies, Anabelle ^a   d'Adda di Fagagna, Fabrizio ^b  

^a DE DUVE INSTITUTE   (Belgium)

^b FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

Author keywords

Ageing; Cellular senescence; Chromatin; Epigenetic alterations; Heterochromatin; Methylation; Oncogene

Indexed keywords

DNA METHYLTRANSFERASE 1; GENOMIC DNA; HETEROCHROMATIN PROTEIN 1; UNTRANSLATED RNA;

CANCER CELL; CANCER GROWTH; CANCER RISK; CARCINOGENESIS; CELL AGING; CELL CYCLE ARREST; CELL DIVISION; CELL PROLIFERATION; CELL RENEWAL; CELLULAR STRESS RESPONSE; CHROMATIN; CPG ISLAND; DNA DAMAGE; DNA METHYLATION; EPIGENETICS; GENE EXPRESSION; GENE FUNCTION; HISTONE MODIFICATION; HUMAN; NONHUMAN; PHENOTYPE; PROMOTER REGION; REVIEW; RNA INTERFERENCE; TUMOR GROWTH; TUMOR SUPPRESSOR GENE; UPREGULATION;

CELL AGING; CELL TRANSFORMATION, NEOPLASTIC; CPG ISLANDS; DNA METHYLATION; EPIGENESIS, GENETIC; HUMANS; NEOPLASMS; ONCOGENES; PROMOTER REGIONS, GENETIC;

EID: 82755160671     PISSN: 1044579X     EISSN: 10963650     Source Type: Journal    
DOI: 10.1016/j.semcancer.2011.09.003     Document Type: Review

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