-
1
-
-
84882891103
-
Cadmium
-
Nordberg GF, Fowler BA, Nordberg M, Friberg LT (eds). Academic Press: Burlington, MA, USA
-
Nordberg GF, Nogawa K, Nordberg M, Friberg LT. Cadmium. In: Nordberg GF, Fowler BA, Nordberg M, Friberg LT (eds). Handbook on the Toxicology of Metals. Academic Press: Burlington, MA, USA, 2007, pp 445-486.
-
(2007)
Handbook on the Toxicology of Metals
, pp. 445-486
-
-
Nordberg, G.F.1
Nogawa, K.2
Nordberg, M.3
Friberg, L.T.4
-
2
-
-
84866309713
-
Mechanisms of cadmium-induced proximal tubule injury: New insights with implications for biomonitoring and therapeutic interventions
-
Prozialeck WC, Edwards JR. Mechanisms of cadmium-induced proximal tubule injury: new insights with implications for biomonitoring and therapeutic interventions. J Pharmacol Exp Ther 2012; 343: 2-12.
-
(2012)
J Pharmacol Exp Ther
, vol.343
, pp. 2-12
-
-
Prozialeck, W.C.1
Edwards, J.R.2
-
3
-
-
0037603262
-
Cadmium alters the localization of N-cadherin, E-cadherin, and β-catenin in the proximal tubule epithelium
-
Prozialeck WC, Lamar PC, Lynch SM. Cadmium alters the localization of N-cadherin, E-cadherin, and β-catenin in the proximal tubule epithelium. Toxicol Appl Pharmacol 2003; 189: 180-195.
-
(2003)
Toxicol Appl Pharmacol
, vol.189
, pp. 180-195
-
-
Prozialeck, W.C.1
Lamar, P.C.2
Lynch, S.M.3
-
5
-
-
84873404635
-
Effects of cadmium on the sub-cellular localization of β-catenin and β-catenin-regulated gene expression in NRK-52E cells
-
Edwards JR, Kolman K, Lamar PC, Chandar N, Fay MJ, Prozialeck WC. Effects of cadmium on the sub-cellular localization of β-catenin and β-catenin-regulated gene expression in NRK-52E cells. Biometals 2013; 26: 33-42.
-
(2013)
Biometals
, vol.26
, pp. 33-42
-
-
Edwards, J.R.1
Kolman, K.2
Lamar, P.C.3
Chandar, N.4
Fay, M.J.5
Prozialeck, W.C.6
-
6
-
-
34548329097
-
Cadmium induces nuclear translocation of β-catenin and increases expression of c-myc and Abcb1a in kidney proximal tubule cells
-
Thévenod F, Wolff NA, Bork U, Lee W-K, Abouhamed M. Cadmium induces nuclear translocation of β-catenin and increases expression of c-myc and Abcb1a in kidney proximal tubule cells. Biometals 2007; 20: 807-820.
-
(2007)
Biometals
, vol.20
, pp. 807-820
-
-
Thévenod, F.1
Wolff, N.A.2
Bork, U.3
Lee, W.-K.4
Abouhamed, M.5
-
7
-
-
77954215506
-
Notch signaling: Emerging molecular targets for cancer therapy
-
Yin L, Velazquez OC, Liu Z-J. Notch signaling: emerging molecular targets for cancer therapy. Biochem Pharmacol 2010; 80: 690-701.
-
(2010)
Biochem Pharmacol
, vol.80
, pp. 690-701
-
-
Yin, L.1
Velazquez, O.C.2
Liu, Z.-J.3
-
9
-
-
84880306937
-
The Notch signaling pathway as a mediator of tumor survival
-
Capaccione KM, Pine SR. The Notch signaling pathway as a mediator of tumor survival. Carcinogenesis 2013; 34: 1420-1430.
-
(2013)
Carcinogenesis
, vol.34
, pp. 1420-1430
-
-
Capaccione, K.M.1
Pine, S.R.2
-
11
-
-
77956309916
-
Notch targets and their regulation
-
Bray S, Bernard F. Notch targets and their regulation. Curr Top Dev Biol 2010; 92: 253-275.
-
(2010)
Curr Top Dev Biol
, vol.92
, pp. 253-275
-
-
Bray, S.1
Bernard, F.2
-
12
-
-
79955481383
-
The Notch signaling pathway: Molecular basis of cell context dependency
-
Schwanbeck R, Martini S, Bernoth K, Just U. The Notch signaling pathway: molecular basis of cell context dependency. Eur J Cell Biol 2011; 90: 572-581.
-
(2011)
Eur J Cell Biol
, vol.90
, pp. 572-581
-
-
Schwanbeck, R.1
Martini, S.2
Bernoth, K.3
Just, U.4
-
13
-
-
68849097965
-
Expression and clinical significance of Notch receptors in human renal cell carcinoma
-
Sun S, Du R, Gao J, Ning X, Xie H, Lin X et al. Expression and clinical significance of Notch receptors in human renal cell carcinoma. Pathology 2009; 41: 335-341.
-
(2009)
Pathology
, vol.41
, pp. 335-341
-
-
Sun, S.1
Du, R.2
Gao, J.3
Ning, X.4
Xie, H.5
Lin, X.6
-
14
-
-
0033784843
-
The transcription factor Snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
-
Cano A, Pérez-Moreno MA, Rodrigo I, Locascio A, Blanco MJ, del Barrio MG et al. The transcription factor Snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat Cell Biol 2000; 2: 76-83.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 76-83
-
-
Cano, A.1
Pérez-Moreno, M.A.2
Rodrigo, I.3
Locascio, A.4
Blanco, M.J.5
Del Barrio, M.G.6
-
15
-
-
0033789680
-
The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells
-
Batlle E, Sancho E, Franci C, Domínguez D, Monfar M, Baulida J et al. The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nat Cell Biol 2000; 2: 84-89.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 84-89
-
-
Batlle, E.1
Sancho, E.2
Franci, C.3
Domínguez, D.4
Monfar, M.5
Baulida, J.6
-
16
-
-
77953541796
-
Notch mediated epithelial to mesenchymal transformation is associated with increased expression of the Snail transcription factor
-
Saad S, Stanners SR, Yong R, Tang O, Pollock CA. Notch mediated epithelial to mesenchymal transformation is associated with increased expression of the Snail transcription factor. Int J Biochem Cell Biol 2010; 42: 1115-1122.
-
(2010)
Int J Biochem Cell Biol
, vol.42
, pp. 1115-1122
-
-
Saad, S.1
Stanners, S.R.2
Yong, R.3
Tang, O.4
Pollock, C.A.5
-
17
-
-
84859485240
-
Notch, apoptosis and cancer
-
Dang TP. Notch, apoptosis and cancer. Adv Exp Med Biol 2012; 727: 199-209.
-
(2012)
Adv Exp Med Biol
, vol.727
, pp. 199-209
-
-
Dang, T.P.1
-
18
-
-
34248175814
-
Regulation of Notch1 gene expression by p53 in epithelial cells
-
Yugawa T, Handa K, Narisawa-Saito M, Ohno S, Fujita M, Kiyono T. Regulation of Notch1 gene expression by p53 in epithelial cells. Mol Cell Biol 2007; 27: 3732-3742.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 3732-3742
-
-
Yugawa, T.1
Handa, K.2
Narisawa-Saito, M.3
Ohno, S.4
Fujita, M.5
Kiyono, T.6
-
19
-
-
70450257539
-
P53-dependent control of transactivation of the Pen2 promoter by presenilins
-
Dunys J, Sevalle J, Giaime E, Pardossi-Piquard R, Vitek MP, Renbaum P et al. p53-dependent control of transactivation of the Pen2 promoter by presenilins. J Cell Sci 2009; 122: 4003-4008.
-
(2009)
J Cell Sci
, vol.122
, pp. 4003-4008
-
-
Dunys, J.1
Sevalle, J.2
Giaime, E.3
Pardossi-Piquard, R.4
Vitek, M.P.5
Renbaum, P.6
-
21
-
-
84876705197
-
Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxia
-
Díaz B, Yuen A, Iizuka S, Higashiyama S, Courtneidge SA. Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxia. J Cell Biol 2013; 201: 279-292.
-
(2013)
J Cell Biol
, vol.201
, pp. 279-292
-
-
Díaz, B.1
Yuen, A.2
Iizuka, S.3
Higashiyama, S.4
Courtneidge, S.A.5
-
22
-
-
1642576036
-
The anti-apoptotic effect of Notch-1 requires p56lck-dependent, Akt/PKB-mediated signaling in T cells
-
Sade H, Krishna S, Sarin A. The anti-apoptotic effect of Notch-1 requires p56lck-dependent, Akt/PKB-mediated signaling in T cells. J Biol Chem 2004; 279: 2937-2944.
-
(2004)
J Biol Chem
, vol.279
, pp. 2937-2944
-
-
Sade, H.1
Krishna, S.2
Sarin, A.3
-
23
-
-
84887242051
-
New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: Targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia
-
Hales EC, Taub JW, Matherly LH. New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia. Cell Signal 2014; 26: 149-161.
-
(2014)
Cell Signal
, vol.26
, pp. 149-161
-
-
Hales, E.C.1
Taub, J.W.2
Matherly, L.H.3
-
24
-
-
84883193377
-
Notch activation promotes endothelial survival through a PI3K-Slug axis
-
Chang L, Wong F, Niessen K, Karsan A. Notch activation promotes endothelial survival through a PI3K-Slug axis. Microvasc Res 2013; 89: 80-85.
-
(2013)
Microvasc Res
, vol.89
, pp. 80-85
-
-
Chang, L.1
Wong, F.2
Niessen, K.3
Karsan, A.4
-
25
-
-
55849139852
-
Notch1 is an effector of Akt and hypoxia in melanoma development
-
Bedogni B, Warneke JA, Nickoloff BJ, Giaccia AJ, Powell MB. Notch1 is an effector of Akt and hypoxia in melanoma development. J Clin Invest 2008; 118: 3660-3670.
-
(2008)
J Clin Invest
, vol.118
, pp. 3660-3670
-
-
Bedogni, B.1
Warneke, J.A.2
Nickoloff, B.J.3
Giaccia, A.J.4
Powell, M.B.5
-
26
-
-
41749121487
-
Reciprocal regulation of Notch and PI3K/Akt signalling in T-ALL cells in vitro
-
Calzavara E, Chiaramonte R, Cesana D, Basile A, Sherbet GV, Comi P. Reciprocal regulation of Notch and PI3K/Akt signalling in T-ALL cells in vitro. J Cell Biochem 2008; 103: 1405-1412.
-
(2008)
J Cell Biochem
, vol.103
, pp. 1405-1412
-
-
Calzavara, E.1
Chiaramonte, R.2
Cesana, D.3
Basile, A.4
Sherbet, G.V.5
Comi, P.6
-
27
-
-
79953131280
-
Angiopoietin-1/Tie2 signal augments basal Notch signal controlling vascular quiescence by inducing delta-like 4 expression through AKT-mediated activation of β-catenin
-
Zhang J, Fukuhara S, Sako K, Takenouchi T, Kitani H, Kume T et al. Angiopoietin-1/Tie2 signal augments basal Notch signal controlling vascular quiescence by inducing delta-like 4 expression through AKT-mediated activation of β-catenin. J Biol Chem 2011; 286: 8055-8066.
-
(2011)
J Biol Chem
, vol.286
, pp. 8055-8066
-
-
Zhang, J.1
Fukuhara, S.2
Sako, K.3
Takenouchi, T.4
Kitani, H.5
Kume, T.6
-
28
-
-
84863317139
-
Notch1 activation promotes renal cell carcinoma growth via PI3K/Akt signaling
-
Xu L, Zhu Y, Xu J, Wu K, Li J, Xu W et al. Notch1 activation promotes renal cell carcinoma growth via PI3K/Akt signaling. Cancer Sci 2012; 103: 1253-1258.
-
(2012)
Cancer Sci
, vol.103
, pp. 1253-1258
-
-
Xu, L.1
Zhu, Y.2
Xu, J.3
Wu, K.4
Li, J.5
Xu, W.6
-
29
-
-
0034805815
-
Cadmium induces phosphorylation of p53 at serine 15 in MCF-7 cells
-
Matsuoka M, Igisu H. Cadmium induces phosphorylation of p53 at serine 15 in MCF-7 cells. Biochem Biophys Res Commun 2001; 282: 1120-1125.
-
(2001)
Biochem Biophys Res Commun
, vol.282
, pp. 1120-1125
-
-
Matsuoka, M.1
Igisu, H.2
-
30
-
-
84893947811
-
PI3K signaling mediates diverse regulation of ATF4 expression for the survival of HK-2 cells exposed to cadmium
-
Fujiki K, Inamura H, Matsuoka M. PI3K signaling mediates diverse regulation of ATF4 expression for the survival of HK-2 cells exposed to cadmium. Arch Toxicol 2014; 88: 403-414.
-
(2014)
Arch Toxicol
, vol.88
, pp. 403-414
-
-
Fujiki, K.1
Inamura, H.2
Matsuoka, M.3
-
31
-
-
33747874155
-
Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors
-
Fan X, Matsui W, Khaki L, Stearns D, Chun J, Li Y-M et al. Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors. Cancer Res 2006; 66: 7445-7452.
-
(2006)
Cancer Res
, vol.66
, pp. 7445-7452
-
-
Fan, X.1
Matsui, W.2
Khaki, L.3
Stearns, D.4
Chun, J.5
Li, Y.-M.6
-
32
-
-
79952005667
-
Cadmium induces phosphorylation and stabilization of c-Fos in HK-2 renal proximal tubular cells
-
Iwatsuki M, Inageda K, Matsuoka M. Cadmium induces phosphorylation and stabilization of c-Fos in HK-2 renal proximal tubular cells. Toxicol Appl Pharmacol 2011; 251: 209-216.
-
(2011)
Toxicol Appl Pharmacol
, vol.251
, pp. 209-216
-
-
Iwatsuki, M.1
Inageda, K.2
Matsuoka, M.3
-
33
-
-
0030003538
-
Signal transduction by activated mNotch: Importance of proteolytic processing and its regulation by the extracellular domain
-
Kopan R, Schroeter EH, Weintraub H, Nye JS. Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain. Proc Natl Acad Sci USA 1996; 93: 1683-1688.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 1683-1688
-
-
Kopan, R.1
Schroeter, E.H.2
Weintraub, H.3
Nye, J.S.4
-
34
-
-
0030667702
-
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
-
Shieh S-Y, Ikeda M, Taya Y, Prives C. DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell 1997; 91: 325-334.
-
(1997)
Cell
, vol.91
, pp. 325-334
-
-
Shieh, S.-Y.1
Ikeda, M.2
Taya, Y.3
Prives, C.4
-
35
-
-
84859270591
-
Notch signaling mediates TGF-β1-induced epithelial-mesenchymal transition through the induction of Snai1
-
Matsuno Y, Coelho AL, Jarai G, Westwick J, Hogaboam CM. Notch signaling mediates TGF-β1-induced epithelial-mesenchymal transition through the induction of Snai1. Int J Biochem Cell Biol 2012; 44: 776-789.
-
(2012)
Int J Biochem Cell Biol
, vol.44
, pp. 776-789
-
-
Matsuno, Y.1
Coelho, A.L.2
Jarai, G.3
Westwick, J.4
Hogaboam, C.M.5
-
36
-
-
9144246932
-
Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation
-
Timmerman LA, Grego-Bessa J, Raya A, Bertrán E, Pérez-Pomares JM, Díez J et al. Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation. Genes Dev 2004; 18: 99-115.
-
(2004)
Genes Dev
, vol.18
, pp. 99-115
-
-
Timmerman, L.A.1
Grego-Bessa, J.2
Raya, A.3
Bertrán, E.4
Pérez-Pomares, J.M.5
Díez, J.6
-
37
-
-
44049090235
-
Notch signaling mediates hypoxia-induced tumor cell migration and invasion
-
Sahlgren C, Gustafsson MV, Jin S, Poellinger L, Lendahl U. Notch signaling mediates hypoxia-induced tumor cell migration and invasion. Proc Natl Acad Sci USA 2008; 105: 6392-6397.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 6392-6397
-
-
Sahlgren, C.1
Gustafsson, M.V.2
Jin, S.3
Poellinger, L.4
Lendahl, U.5
-
38
-
-
12144266241
-
Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription: Implications for the epithelialmesenchymal transition
-
Bachelder RE, Yoon S-O, Franci C, de Herreros AG, Mercurio AM. Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription: implications for the epithelialmesenchymal transition. J Cell Biol 2005; 168: 29-33.
-
(2005)
J Cell Biol
, vol.168
, pp. 29-33
-
-
Bachelder, R.E.1
Yoon, S.-O.2
Franci, C.3
De Herreros, A.G.4
Mercurio, A.M.5
-
39
-
-
0029587224
-
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
-
Cross DAE, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 1995; 378: 785-789.
-
(1995)
Nature
, vol.378
, pp. 785-789
-
-
Cross, D.A.E.1
Alessi, D.R.2
Cohen, P.3
Andjelkovich, M.4
Hemmings, B.A.5
-
40
-
-
79955535043
-
Numb protects renal proximal tubular cells from puromycin aminonucleoside-induced apoptosis through inhibiting Notch signaling pathway
-
Ding X, Zhu F, Li T, Zhou Q, Hou FF, Nie J. Numb protects renal proximal tubular cells from puromycin aminonucleoside-induced apoptosis through inhibiting Notch signaling pathway. Int J Biol Sci 2011; 7: 269-278.
-
(2011)
Int J Biol Sci
, vol.7
, pp. 269-278
-
-
Ding, X.1
Zhu, F.2
Li, T.3
Zhou, Q.4
Hou, F.F.5
Nie, J.6
-
41
-
-
38149085894
-
Hyperthermia inhibits cell proliferation and induces apoptosis: Relative signaling status of P53, S100A4, and Notch in heat sensitive and resistant cell lines
-
Basile A, Biziato D, Sherbet GV, Comi P, Cajone F. Hyperthermia inhibits cell proliferation and induces apoptosis: relative signaling status of P53, S100A4, and Notch in heat sensitive and resistant cell lines. J Cell Biochem 2008; 103: 212-220.
-
(2008)
J Cell Biochem
, vol.103
, pp. 212-220
-
-
Basile, A.1
Biziato, D.2
Sherbet, G.V.3
Comi, P.4
Cajone, F.5
-
42
-
-
84875190140
-
Notch pathway is involved in high glucose-induced apoptosis in podocytes via Bcl-2 and p53 pathways
-
Gao F, Yao M, Shi Y, Hao J, Ren Y, Liu Q et al. Notch pathway is involved in high glucose-induced apoptosis in podocytes via Bcl-2 and p53 pathways. J Cell Biochem 2013; 114: 1029-1038.
-
(2013)
J Cell Biochem
, vol.114
, pp. 1029-1038
-
-
Gao, F.1
Yao, M.2
Shi, Y.3
Hao, J.4
Ren, Y.5
Liu, Q.6
-
43
-
-
79960815940
-
Notch-1 activation-dependent p53 restoration contributes to resveratrol-induced apoptosis in glioblastoma cells
-
Lin H, Xiong W, Zhang X, Liu B, Zhang W, Zhang Y et al. Notch-1 activation-dependent p53 restoration contributes to resveratrol-induced apoptosis in glioblastoma cells. Oncol Rep 2011; 26: 925-930.
-
(2011)
Oncol Rep
, vol.26
, pp. 925-930
-
-
Lin, H.1
Xiong, W.2
Zhang, X.3
Liu, B.4
Zhang, W.5
Zhang, Y.6
-
44
-
-
56649100788
-
Presenilin 1/γ-secretase is associated with cadmium-induced E-cadherin cleavage and COX-2 gene expression in T47D breast cancer cells
-
Park CS, Kim OS, Yun S-M, Jo SA, Jo I, Koh YH. Presenilin 1/γ-secretase is associated with cadmium-induced E-cadherin cleavage and COX-2 gene expression in T47D breast cancer cells. Toxicol Sci 2008; 106: 413-422.
-
(2008)
Toxicol Sci
, vol.106
, pp. 413-422
-
-
Park, C.S.1
Kim, O.S.2
Yun, S.-M.3
Jo, S.A.4
Jo, I.5
Koh, Y.H.6
-
45
-
-
0036014932
-
Transforming growth factor-β induces renal epithelial jagged-1 expression in fibrotic disease
-
Morrissey J, Guo G, Moridaira K, Fitzgerald M, McCracken R, Tolley T et al. Transforming growth factor-β induces renal epithelial jagged-1 expression in fibrotic disease. J Am Soc Nephrol 2002; 13: 1499-1508.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 1499-1508
-
-
Morrissey, J.1
Guo, G.2
Moridaira, K.3
Fitzgerald, M.4
McCracken, R.5
Tolley, T.6
-
46
-
-
43749117539
-
Expression and function of the Delta-1/Notch-2/Hes-1 pathway during experimental acute kidney injury
-
Kobayashi T, Terada Y, Kuwana H, Tanaka H, Okado T, Kuwahara M et al. Expression and function of the Delta-1/Notch-2/Hes-1 pathway during experimental acute kidney injury. Kidney Int 2008; 73: 1240-1250.
-
(2008)
Kidney Int
, vol.73
, pp. 1240-1250
-
-
Kobayashi, T.1
Terada, Y.2
Kuwana, H.3
Tanaka, H.4
Okado, T.5
Kuwahara, M.6
-
47
-
-
42949165654
-
Neuralized-like 1 (Neurl1) targeted to the plasma membrane by N-myristoylation regulates the Notch ligand Jagged1
-
Koutelou E, Sato S, Tomomori-Sato C, Florens L, Swanson SK, Washburn MP et al. Neuralized-like 1 (Neurl1) targeted to the plasma membrane by N-myristoylation regulates the Notch ligand Jagged1. J Biol Chem 2008; 283: 3846-3853.
-
(2008)
J Biol Chem
, vol.283
, pp. 3846-3853
-
-
Koutelou, E.1
Sato, S.2
Tomomori-Sato, C.3
Florens, L.4
Swanson, S.K.5
Washburn, M.P.6
-
48
-
-
67649641505
-
Role of oxidative stress in cadmium toxicity and carcinogenesis
-
Liu J, Qu W, Kadiiska MB. Role of oxidative stress in cadmium toxicity and carcinogenesis. Toxicol Appl Pharmacol 2009; 238: 209-214.
-
(2009)
Toxicol Appl Pharmacol
, vol.238
, pp. 209-214
-
-
Liu, J.1
Qu, W.2
Kadiiska, M.B.3
-
49
-
-
79955403347
-
Cadmium toxicity is caused by accumulation of p53 through the down-regulation of Ube2d family genes in vitro and in vivo
-
Tokumoto M, Fujiwara Y, Shimada A, Hasegawa T, Seko Y, Nagase H et al. Cadmium toxicity is caused by accumulation of p53 through the down-regulation of Ube2d family genes in vitro and in vivo. J Toxicol Sci 2011; 36: 191-200.
-
(2011)
J Toxicol Sci
, vol.36
, pp. 191-200
-
-
Tokumoto, M.1
Fujiwara, Y.2
Shimada, A.3
Hasegawa, T.4
Seko, Y.5
Nagase, H.6
-
50
-
-
66449118214
-
Switching Akt: From survival signaling to deadly response
-
Los M, Maddika S, Erb B, Schulze-Osthoff K. Switching Akt: from survival signaling to deadly response. Bioessays 2009; 31: 492-495.
-
(2009)
Bioessays
, vol.31
, pp. 492-495
-
-
Los, M.1
Maddika, S.2
Erb, B.3
Schulze-Osthoff, K.4
-
51
-
-
84884149973
-
Interference with Akt signaling protects against myocardial infarction and death by limiting the consequences of oxidative stress
-
Kerr BA, Ma L, West XZ, Ding L, Malinin NL, Weber ME et al. Interference with Akt signaling protects against myocardial infarction and death by limiting the consequences of oxidative stress. Sci Signal 2013; 6: ra67.
-
(2013)
Sci Signal
, vol.6
-
-
Kerr, B.A.1
Ma, L.2
West, X.Z.3
Ding, L.4
Malinin, N.L.5
Weber, M.E.6
-
52
-
-
79551488995
-
Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death
-
Chen L, Xu B, Liu L, Luo Y, Zhou H, Chen W et al. Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death. Free Radic Biol Med 2011; 50: 624-632.
-
(2011)
Free Radic Biol Med
, vol.50
, pp. 624-632
-
-
Chen, L.1
Xu, B.2
Liu, L.3
Luo, Y.4
Zhou, H.5
Chen, W.6
-
53
-
-
77951880179
-
Notch-1 stimulates survival of lung adenocarcinoma cells during hypoxia by activating the IGF-1R pathway
-
Eliasz S, Liang S, Chen Y, De Marco MA, Machek O, Skucha S et al. Notch-1 stimulates survival of lung adenocarcinoma cells during hypoxia by activating the IGF-1R pathway. Oncogene 2010; 29: 2488-2498.
-
(2010)
Oncogene
, vol.29
, pp. 2488-2498
-
-
Eliasz, S.1
Liang, S.2
Chen, Y.3
De Marco, M.A.4
Machek, O.5
Skucha, S.6
-
54
-
-
34948908663
-
Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia
-
Palomero T, Sulis ML, Cortina M, Real PJ, Barnes K, Ciofani M et al. Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia. Nat Med 2007; 13: 1203-1210.
-
(2007)
Nat Med
, vol.13
, pp. 1203-1210
-
-
Palomero, T.1
Sulis, M.L.2
Cortina, M.3
Real, P.J.4
Barnes, K.5
Ciofani, M.6
-
55
-
-
77957790485
-
Jagged/Notch signalling is required for a subset of TGFb1 responses in human kidney epithelial cells
-
Nyhan KC, Faherty N, Murray G, Cooey LB, Godson C, Crean JK et al. Jagged/Notch signalling is required for a subset of TGFb1 responses in human kidney epithelial cells. Biochim Biophys Acta 2010; 1803: 1386-1395.
-
(2010)
Biochim Biophys Acta
, vol.1803
, pp. 1386-1395
-
-
Nyhan, K.C.1
Faherty, N.2
Murray, G.3
Cooey, L.B.4
Godson, C.5
Crean, J.K.6
-
56
-
-
84857147817
-
Hypoxia-induced down-regulation of microRNA-34a promotes EMT by targeting the Notch signaling pathway in tubular epithelial cells
-
Du R, Sun W, Xia L, Zhao A, Yu Y, Zhao L et al. Hypoxia-induced down-regulation of microRNA-34a promotes EMT by targeting the Notch signaling pathway in tubular epithelial cells. PLoS One 2012; 7: e30771.
-
(2012)
PLoS One
, vol.7
-
-
Du, R.1
Sun, W.2
Xia, L.3
Zhao, A.4
Yu, Y.5
Zhao, L.6
-
57
-
-
77951957445
-
Cadmium induces Wnt signaling to upregulate proliferation and survival genes in sub-confluent kidney proximal tubule cells
-
Chakraborty PK, Lee W-K, Molitor M, Wolff NA, Thévenod F. Cadmium induces Wnt signaling to upregulate proliferation and survival genes in sub-confluent kidney proximal tubule cells. Mol Cancer 2010; 9: 102.
-
(2010)
Mol Cancer
, vol.9
, pp. 102
-
-
Chakraborty, P.K.1
Lee, W.-K.2
Molitor, M.3
Wolff, N.A.4
Thévenod, F.5
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