Effects of cadmium on the sub-cellular localization of β-catenin and β-catenin-regulated gene expression in NRK-52E cells

BioMetals

Volumn 26, Issue 1, 2013, Pages 33-42

  Edwards, Joshua R ^a   Kolman, Kevin ^b   Lamar, Peter C ^a   Chandar, Nalini ^b   Fay, Michael J ^a   Prozialeck, Walter C ^a  

^a MIDWESTERN UNIVERSITY   (United States)

^b MIDWESTERN UNIVERSITY   (United States)

Author keywords

catenin; Cadmium; E cadherin; N cadherin; NRK 52E cells

Indexed keywords

BETA CATENIN; CADHERIN; CADMIUM; CYCLIN D1; MATRILYSIN; MYC PROTEIN; PROTEIN C JUN;

ANIMAL CELL; ARTICLE; BETA CATENIN GENE; CELL COMMUNICATION; CELL CONTACT; CELL FRACTIONATION; CELL GROWTH; CELL SURFACE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GENE ACTIVATION; GENE CONSTRUCT; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; KIDNEY PROXIMAL TUBULE; NONHUMAN; RAT; UPREGULATION;

ANIMALS; BETA CATENIN; CADHERINS; CADMIUM CHLORIDE; CELL ADHESION; CELL LINE; CELL NUCLEUS; CELL SURVIVAL; ENVIRONMENTAL POLLUTANTS; KIDNEY; LITHIUM; PROTEIN TRANSPORT; RATS; TRANSCRIPTIONAL ACTIVATION; TRANSCRIPTOME;

RATTUS;

EID: 84873404635     PISSN: 09660844     EISSN: 15728773     Source Type: Journal    
DOI: 10.1007/s10534-012-9592-0     Document Type: Article

References (36)

1. Chakraborty PK, Lee WK, Molitor M, Wolff NA, Thevenod F (2010a) Cadmium induces Wnt signaling to upregulate proliferation and survival genes in sub-confluent kidney proximal tubule cells. Mol Cancer 102
2. Chakraborty PK, Scharner B, Jurasovic J, Messner B, Bernhard D, Thevenod F (2010b) Chronic cadmium exposure induces transcriptional activation of the Wnt pathway and upregulation of epithelial-to-mesenchymal transition markers in mouse kidney. Toxicol Lett 1:69-76
3. Elghany NA, Schumacher MC, Slattery ML, West DW, Lee JS (1990) Occupation, cadmium exposure, and prostate cancer. Epidemiology 2:107-115
4. Fagotto F, Gluck U, Gumbiner BM (1998) Nuclear localization signal-independent and importin/karyopherin-independent nuclear import of beta-catenin. Curr Biol 4:181-190
5. Hechtenberg S, Schafer T, Benters J, Beyersmann D (1996) Effects of cadmium on cellular calcium and proto-oncogene expression. Ann Clin Lab Sci 6:512-521
6. Howe LR, Subbaramaiah K, Chung WJ, Dannenberg AJ, Brown AM(1999) Transcriptional activation of cyclooxygenase-2 in Wnt-1-transformed mouse mammary epithelial cells. Cancer Res 7:1572-1577
7. Hu J, Mao Y, White K (2002) Renal cell carcinoma and occupational exposure to chemicals in Canada. Occup Med (Lond) 3:157-164
8. Jain R, Lammert E (2009) Cell-cell interactions in the endocrine pancreas. Diabetes Obes Metab 159-167
9. Jarup L, Akesson A (2009) Current status of cadmium as an environmental health problem. Toxicol Appl Pharmacol 3:201-208
10. Jiang G, Xu L, Song S, Zhu C, Wu Q, Zhang L, Wu L (2008) Effects of long-term low-dose cadmium exposure on genomic DNA methylation in human embryo lung fibroblast cells. Toxicology 1:49-55
11. Lei LJ, Jin TY, Zhou YF (2007) Insulin expression in rats exposed to cadmium. Biomed Environ Sci 4:295-301
12. Lopez E, Arce C, Oset-Gasque MJ, Canadas S, Gonzalez MP (2006) Cadmium induces reactive oxygen species generation and lipid peroxidation in cortical neurons in culture. Free Radic Biol Med 6:940-951
13. MacDonald BT, Tamai K, He X (2009) Wnt/beta-catenin signaling: Components, mechanisms, and diseases. Dev Cell 1:9-26
14. Matsuoka M, Call KM (1995) Cadmium-induced expression of immediate early genes in LLC-PK1 cells. Kidney Int 2:383-389
15. Nelson WJ, Nusse R (2004) Convergence of Wnt, beta-catenin, and cadherin pathways. Science 5663:1483-1487
16. Niewenhuis RJ, Dimitriu C, Prozialeck WC (1997) Ultrastructural characterization of the early changes in intercellular junctions in response to cadmium (Cd2 ?) exposure in LLC-PK1 cells. Toxicol Appl Pharmacol 1:1-12
17. Pearson CA, Prozialeck WC (2001) E-Cadherin, beta-Catenin and cadmium carcinogenesis. Med Hypotheses 5:573-581
18. Pearson CA, Lamar PC, Prozialeck WC (2003) Effects of cadmium on E-cadherin and VE-cadherin in mouse lung. Life Sci 11:1303-1320
19. Prozialeck WC (2000) Evidence that E-cadherin may be a target for cadmium toxicity in epithelial cells. Toxicol Appl Pharmacol 3:231-249
20. Prozialeck WC, Edwards JR (2007) Cell adhesion molecules in chemically-induced renal injury. Pharmacol Ther 1:74-93
21. Prozialeck WC, Edwards JR (2012) Mechanisms of Cadmium-Induced proximal tubule injury: New Insights with Implications for biomonitoring and therapeutic interventions. J Pharmacol Exp Ther
22. Prozialeck WC, Lamar PC (1997) Cadmium (Cd2 ?) disrupts E-cadherin-dependent cell-cell junctions in MDCK cells. In Vitro Cell Dev Biol Anim 7:516-526
23. Prozialeck WC, Niewenhuis RJ (1991a) Cadmium (Cd2 ?) disrupts Ca(2 ?)-dependent cell-cell junctions and alters the pattern of E-cadherin immunofluorescence in LLCPK1 cells. Biochem Biophys Res Commun 3:1118-1124
24. Prozialeck WC, Niewenhuis RJ (1991b) Cadmium (Cd2 ?) disrupts intercellular junctions and actin filaments in LLCPK1 cells. Toxicol Appl Pharmacol 1:81-97
25. Prozialeck WC, Grunwald GB, Dey PM, Reuhl KR, Parrish AR (2002) Cadherins and NCAM as potential targets in metal toxicity. Toxicol Appl Pharmacol 3:255-265
26. Prozialeck WC, Lamar PC, Lynch SM (2003) Cadmium alters the localization of N-cadherin, E-cadherin, and beta-catenin in the proximal tubule epithelium. Toxicol Appl Pharmacol 3:180-195
27. Prozialeck WC, Edwards JR, Woods JM (2006) The vascular endothelium as a target of cadmium toxicity. Life Sci 16:1493-1506
28. Prozialeck WC, Vaidya VS, Liu J, Waalkes MP, Edwards JR, Lamar PC, Bernard AM, Dumont X, Bonventre JV (2007) Kidney injury molecule-1 is an early biomarker of cadmium nephrotoxicity. Kidney Int 8:985-993
29. Shaikh ZA, Vu TT, Zaman K (1999) Oxidative stress as a mechanism of chronic cadmium-induced hepatotoxicity and renal toxicity and protection by antioxidants. Toxicol Appl Pharmacol 3:256-263
30. Sinha D, Wang Z, Ruchalski KL, Levine JS, Krishnan S, Lieberthal W, Schwartz JH, Borkan SC (2005) Lithium activates the Wnt and phosphatidylinositol 3-kinase Akt signaling pathways to promote cell survival in the absence of soluble survival factors.AmJ PhysiolRenal Physiol 4:F703-F713
31. Stayner L, Smith R, Thun M, Schnorr T, Lemen R (1992) A dose-response analysis and quantitative assessment of lung cancer risk and occupational cadmium exposure. Ann Epidemiol 3:177-194
32. Takiguchi M, Achanzar WE, Qu W, Li G, Waalkes MP (2003) Effects of cadmium on DNA-(Cytosine-5) methyltransferase activity and DNA methylation status during cadmium-induced cellular transformation. Exp Cell Res 2:355-365
33. Thevenod F, Wolff NA, Bork U, Lee WK, Abouhamed M (2007) Cadmium induces nuclear translocation of betacatenin and increases expression of c-myc and Abcb1a in kidney proximal tubule cells. Biometals 5:807-820
34. Thompson J, Wong L, Lau PS, Bannigan J (2008) Adherens junction breakdown in the periderm following cadmium administration in the chick embryo: Distribution of cadherins and associated molecules. Reprod Toxicol 1:39-46
35. Tsanou E, Peschos D, Batistatou A, Charalabopoulos A, Charalabopoulos K (2008) The E-cadherin adhesion molecule and colorectal cancer. A global literature approach. Anticancer Res 6A:3815-3826
36. Waalkes MP (2003) Cadmium carcinogenesis. Mutat Res 1-2:107-120