-
2
-
-
24944444760
-
Notch promotes survival of pre-t cells at the beta-selection checkpoint by regulating cellular metabolism
-
Ciofani M., Zuniga-Pflucker J.C. Notch promotes survival of pre-t cells at the beta-selection checkpoint by regulating cellular metabolism. Nat. Immunol. 2005, 6:881-888.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 881-888
-
-
Ciofani, M.1
Zuniga-Pflucker, J.C.2
-
3
-
-
43249091361
-
Rbp-j, the transcription factor downstream of notch receptors, is essential for the maintenance of vascular homeostasis in adult mice
-
Dou G.R., Wang Y.C., Hu X.B., Hou L.H., Wang C.M., Xu J.F., Wang Y.S., Liang Y.M., Yao L.B., Yang A.G., Han H. Rbp-j, the transcription factor downstream of notch receptors, is essential for the maintenance of vascular homeostasis in adult mice. FASEB J. 2008, 22:1606-1617.
-
(2008)
FASEB J.
, vol.22
, pp. 1606-1617
-
-
Dou, G.R.1
Wang, Y.C.2
Hu, X.B.3
Hou, L.H.4
Wang, C.M.5
Xu, J.F.6
Wang, Y.S.7
Liang, Y.M.8
Yao, L.B.9
Yang, A.G.10
Han, H.11
-
4
-
-
0030696785
-
Fibroblast growth factor-2 inhibits endothelial cell apoptosis by bcl-2-dependent and independent mechanisms
-
Karsan A., Yee E., Poirier G.G., Zhou P., Craig R., Harlan J.M. Fibroblast growth factor-2 inhibits endothelial cell apoptosis by bcl-2-dependent and independent mechanisms. Am. J. Pathol. 1997, 151:1775-1784.
-
(1997)
Am. J. Pathol.
, vol.151
, pp. 1775-1784
-
-
Karsan, A.1
Yee, E.2
Poirier, G.G.3
Zhou, P.4
Craig, R.5
Harlan, J.M.6
-
5
-
-
79955915582
-
A novel tumour-suppressor function for the notch pathway in myeloid leukaemia
-
Klinakis A., Lobry C., Abdel-Wahab O., Oh P., Haeno H., Buonamici S., van De Walle I., Cathelin S., Trimarchi T., Araldi E., Liu C., Ibrahim S., Beran M., Zavadil J., Efstratiadis A., Taghon T., Michor F., Levine R.L., Aifantis I. A novel tumour-suppressor function for the notch pathway in myeloid leukaemia. Nature 2011, 473:230-233.
-
(2011)
Nature
, vol.473
, pp. 230-233
-
-
Klinakis, A.1
Lobry, C.2
Abdel-Wahab, O.3
Oh, P.4
Haeno, H.5
Buonamici, S.6
van De Walle, I.7
Cathelin, S.8
Trimarchi, T.9
Araldi, E.10
Liu, C.11
Ibrahim, S.12
Beran, M.13
Zavadil, J.14
Efstratiadis, A.15
Taghon, T.16
Michor, F.17
Levine, R.L.18
Aifantis, I.19
-
6
-
-
70349859809
-
Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells
-
Kurrey N.K., Jalgaonkar S.P., Joglekar A.V., Ghanate A.D., Chaskar P.D., Doiphode R.Y., Bapat S.A. Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells. Stem Cells 2009, 27:2059-2068.
-
(2009)
Stem Cells
, vol.27
, pp. 2059-2068
-
-
Kurrey, N.K.1
Jalgaonkar, S.P.2
Joglekar, A.V.3
Ghanate, A.D.4
Chaskar, P.D.5
Doiphode, R.Y.6
Bapat, S.A.7
-
7
-
-
1642523576
-
Notch4 inhibits endothelial apoptosis via rbp-jkappa-dependent and -independent pathways
-
MacKenzie F., Duriez P., Wong F., Noseda M., Karsan A. Notch4 inhibits endothelial apoptosis via rbp-jkappa-dependent and -independent pathways. J. Biol. Chem. 2004, 279:11657-11663.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 11657-11663
-
-
MacKenzie, F.1
Duriez, P.2
Wong, F.3
Noseda, M.4
Karsan, A.5
-
8
-
-
33646415906
-
Survival signaling by notch1: mammalian target of rapamycin (mtor)-dependent inhibition of p53
-
Mungamuri S.K., Yang X., Thor A.D., Somasundaram K. Survival signaling by notch1: mammalian target of rapamycin (mtor)-dependent inhibition of p53. Cancer Res. 2006, 66:4715-4724.
-
(2006)
Cancer Res.
, vol.66
, pp. 4715-4724
-
-
Mungamuri, S.K.1
Yang, X.2
Thor, A.D.3
Somasundaram, K.4
-
9
-
-
0036604133
-
Lipopolysaccharide-induced apoptosis of endothelial cells and its inhibition by vascular endothelial growth factor
-
Munshi N., Fernandis A.Z., Cherla R.P., Park I.W., Ganju R.K. Lipopolysaccharide-induced apoptosis of endothelial cells and its inhibition by vascular endothelial growth factor. J. Immunol. 2002, 168:5860-5866.
-
(2002)
J. Immunol.
, vol.168
, pp. 5860-5866
-
-
Munshi, N.1
Fernandis, A.Z.2
Cherla, R.P.3
Park, I.W.4
Ganju, R.K.5
-
10
-
-
48249103470
-
Slug is a direct notch target required for initiation of cardiac cushion cellularization
-
Niessen K., Fu Y., Chang L., Hoodless P.A., McFadden D., Karsan A. Slug is a direct notch target required for initiation of cardiac cushion cellularization. J. Cell Biol. 2008, 182:315-325.
-
(2008)
J. Cell Biol.
, vol.182
, pp. 315-325
-
-
Niessen, K.1
Fu, Y.2
Chang, L.3
Hoodless, P.A.4
McFadden, D.5
Karsan, A.6
-
11
-
-
4744358492
-
Notch activation induces endothelial cell cycle arrest and participates in contact inhibition: role of p21cip1 repression
-
Noseda M., Chang L., McLean G., Grim J.E., Clurman B.E., Smith L.L., Karsan A. Notch activation induces endothelial cell cycle arrest and participates in contact inhibition: role of p21cip1 repression. Mol. Cell Biol. 2004, 24:8813-8822.
-
(2004)
Mol. Cell Biol.
, vol.24
, pp. 8813-8822
-
-
Noseda, M.1
Chang, L.2
McLean, G.3
Grim, J.E.4
Clurman, B.E.5
Smith, L.L.6
Karsan, A.7
-
12
-
-
25444506836
-
Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function
-
Patel N.S., Li J.L., Generali D., Poulsom R., Cranston D.W., Harris A.L. Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function. Cancer Res. 2005, 65:8690-8697.
-
(2005)
Cancer Res.
, vol.65
, pp. 8690-8697
-
-
Patel, N.S.1
Li, J.L.2
Generali, D.3
Poulsom, R.4
Cranston, D.W.5
Harris, A.L.6
-
13
-
-
0029942842
-
Exclusive development of t cell neoplasms in mice transplanted with bone marrow expressing activated notch alleles
-
Pear W.S., Aster J.C., Scott M.L., Hasserjian R.P., Soffer B., Sklar J., Baltimore D. Exclusive development of t cell neoplasms in mice transplanted with bone marrow expressing activated notch alleles. J. Exp. Med. 1996, 183:2283-2291.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2283-2291
-
-
Pear, W.S.1
Aster, J.C.2
Scott, M.L.3
Hasserjian, R.P.4
Soffer, B.5
Sklar, J.6
Baltimore, D.7
-
14
-
-
0038713805
-
The radioresistance biological function of the scf/kit signaling pathway is mediated by the zinc-finger transcription factor slug
-
Perez-Losada J., Sanchez-Martin M., Perez-Caro M., Perez-Mancera P.A., Sanchez-Garcia I. The radioresistance biological function of the scf/kit signaling pathway is mediated by the zinc-finger transcription factor slug. Oncogene 2003, 22:4205-4211.
-
(2003)
Oncogene
, vol.22
, pp. 4205-4211
-
-
Perez-Losada, J.1
Sanchez-Martin, M.2
Perez-Caro, M.3
Perez-Mancera, P.A.4
Sanchez-Garcia, I.5
-
15
-
-
57549098228
-
Impaired notch4 activity elicits endothelial cell activation and apoptosis: implication for transplant arteriosclerosis
-
Quillard T., Coupel S., Coulon F., Fitau J., Chatelais M., Cuturi M.C., Chiffoleau E., Charreau B. Impaired notch4 activity elicits endothelial cell activation and apoptosis: implication for transplant arteriosclerosis. Arterioscler. Thromb. Vasc. Biol. 2008, 28:2258-2265.
-
(2008)
Arterioscler. Thromb. Vasc. Biol.
, vol.28
, pp. 2258-2265
-
-
Quillard, T.1
Coupel, S.2
Coulon, F.3
Fitau, J.4
Chatelais, M.5
Cuturi, M.C.6
Chiffoleau, E.7
Charreau, B.8
-
16
-
-
77949517864
-
Notch2 signaling sensitizes endothelial cells to apoptosis by negatively regulating the key protective molecule survivin
-
Quillard T., Devalliere J., Chatelais M., Coulon F., Seveno C., Romagnoli M., Barille Nion S., Charreau B. Notch2 signaling sensitizes endothelial cells to apoptosis by negatively regulating the key protective molecule survivin. PLoS One 2009, 4:e8244.
-
(2009)
PLoS One
, vol.4
-
-
Quillard, T.1
Devalliere, J.2
Chatelais, M.3
Coulon, F.4
Seveno, C.5
Romagnoli, M.6
Barille Nion, S.7
Charreau, B.8
-
17
-
-
0142259346
-
The role of notch in tumorigenesis: oncogene or tumour suppressor?
-
Radtke F., Raj K. The role of notch in tumorigenesis: oncogene or tumour suppressor?. Nat. Rev. Cancer 2003, 3:756-767.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 756-767
-
-
Radtke, F.1
Raj, K.2
-
18
-
-
2542582293
-
Homocysteine enhances endothelial apoptosis via upregulation of fas-mediated pathways
-
Suhara T., Fukuo K., Yasuda O., Tsubakimoto M., Takemura Y., Kawamoto H., Yokoi T., Mogi M., Kaimoto T., Ogihara T. Homocysteine enhances endothelial apoptosis via upregulation of fas-mediated pathways. Hypertension 2004, 43:1208-1213.
-
(2004)
Hypertension
, vol.43
, pp. 1208-1213
-
-
Suhara, T.1
Fukuo, K.2
Yasuda, O.3
Tsubakimoto, M.4
Takemura, Y.5
Kawamoto, H.6
Yokoi, T.7
Mogi, M.8
Kaimoto, T.9
Ogihara, T.10
-
19
-
-
33846040204
-
Critical role of endothelial notch1 signaling in postnatal angiogenesis
-
Takeshita K., Satoh M., Ii M., Silver M., Limbourg F.P., Mukai Y., Rikitake Y., Radtke F., Gridley T., Losordo D.W., Liao J.K. Critical role of endothelial notch1 signaling in postnatal angiogenesis. Circ. Res. 2007, 100:70-78.
-
(2007)
Circ. Res.
, vol.100
, pp. 70-78
-
-
Takeshita, K.1
Satoh, M.2
Ii, M.3
Silver, M.4
Limbourg, F.P.5
Mukai, Y.6
Rikitake, Y.7
Radtke, F.8
Gridley, T.9
Losordo, D.W.10
Liao, J.K.11
-
20
-
-
0034737984
-
Relation between endothelial cell apoptosis and blood flow direction in human atherosclerotic plaques
-
Tricot O., Mallat Z., Heymes C., Belmin J., Leseche G., Tedgui A. Relation between endothelial cell apoptosis and blood flow direction in human atherosclerotic plaques. Circulation 2000, 101:2450-2453.
-
(2000)
Circulation
, vol.101
, pp. 2450-2453
-
-
Tricot, O.1
Mallat, Z.2
Heymes, C.3
Belmin, J.4
Leseche, G.5
Tedgui, A.6
-
21
-
-
34247596041
-
Ciglitazone ameliorates homocysteine-mediated mitochondrial translocation and matrix metalloproteinase-9 activation in endothelial cells by inducing peroxisome proliferator activated receptor-gamma activity
-
Tyagi N., Moshal K.S., Sen U., Lominadze D., Ovechkin A.V., Tyagi S.C. Ciglitazone ameliorates homocysteine-mediated mitochondrial translocation and matrix metalloproteinase-9 activation in endothelial cells by inducing peroxisome proliferator activated receptor-gamma activity. Cell. Mol. Biol. (Noisy-le-Grand) 2006, 52:21-27.
-
(2006)
Cell. Mol. Biol. (Noisy-le-Grand)
, vol.52
, pp. 21-27
-
-
Tyagi, N.1
Moshal, K.S.2
Sen, U.3
Lominadze, D.4
Ovechkin, A.V.5
Tyagi, S.C.6
-
22
-
-
67650236862
-
Notch1 signaling sensitizes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human hepatocellular carcinoma cells by inhibiting akt/hdm2-mediated p53 degradation and up-regulating p53-dependent dr5 expression
-
Wang C., Qi R., Li N., Wang Z., An H., Zhang Q., Yu Y., Cao X. Notch1 signaling sensitizes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human hepatocellular carcinoma cells by inhibiting akt/hdm2-mediated p53 degradation and up-regulating p53-dependent dr5 expression. J. Biol. Chem. 2009, 284:16183-16190.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 16183-16190
-
-
Wang, C.1
Qi, R.2
Li, N.3
Wang, Z.4
An, H.5
Zhang, Q.6
Yu, Y.7
Cao, X.8
-
23
-
-
77749321234
-
Down-regulation of notch-1 and jagged-1 inhibits prostate cancer cell growth, migration and invasion, and induces apoptosis via inactivation of akt, mtor, and nf-kappab signaling pathways
-
Wang Z., Li Y., Banerjee S., Kong D., Ahmad A., Nogueira V., Hay N., Sarkar F.H. Down-regulation of notch-1 and jagged-1 inhibits prostate cancer cell growth, migration and invasion, and induces apoptosis via inactivation of akt, mtor, and nf-kappab signaling pathways. J. Cell. Biochem. 2010, 109:726-736.
-
(2010)
J. Cell. Biochem.
, vol.109
, pp. 726-736
-
-
Wang, Z.1
Li, Y.2
Banerjee, S.3
Kong, D.4
Ahmad, A.5
Nogueira, V.6
Hay, N.7
Sarkar, F.H.8
-
24
-
-
2942537700
-
Lipopolysaccharide initiates a traf6-mediated endothelial survival signal
-
Wong F., Hull C., Zhande R., Law J., Karsan A. Lipopolysaccharide initiates a traf6-mediated endothelial survival signal. Blood 2004, 103:4520-4526.
-
(2004)
Blood
, vol.103
, pp. 4520-4526
-
-
Wong, F.1
Hull, C.2
Zhande, R.3
Law, J.4
Karsan, A.5
-
25
-
-
27744547091
-
Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma
-
Wu W.S., Heinrichs S., Xu D., Garrison S.P., Zambetti G.P., Adams J.M., Look A.T. Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma. Cell 2005, 123:641-653.
-
(2005)
Cell
, vol.123
, pp. 641-653
-
-
Wu, W.S.1
Heinrichs, S.2
Xu, D.3
Garrison, S.P.4
Zambetti, G.P.5
Adams, J.M.6
Look, A.T.7
-
26
-
-
0035929641
-
Homocysteine induces programmed cell death in human vascular endothelial cells through activation of the unfolded protein response
-
Zhang C., Cai Y., Adachi M.T., Oshiro S., Aso T., Kaufman R.J., Kitajima S. Homocysteine induces programmed cell death in human vascular endothelial cells through activation of the unfolded protein response. J. Biol. Chem. 2001, 276:35867-35874.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 35867-35874
-
-
Zhang, C.1
Cai, Y.2
Adachi, M.T.3
Oshiro, S.4
Aso, T.5
Kaufman, R.J.6
Kitajima, S.7
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