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Volumn 343, Issue 1, 2012, Pages 2-12

Mechanisms of cadmium-induced proximal tubule injury: new insights with implications for biomonitoring and therapeutic interventions

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ALPHA CATENIN; APC PROTEIN; BETA CATENIN; CADMIUM; CHELATING AGENT; CYCLIC AMP; CYCLIN D1; FIBRONECTIN; GLUTATHIONE; GLUTATHIONE TRANSFERASE; GLYCOGEN SYNTHASE KINASE 3BETA; HEME OXYGENASE; MATRILYSIN; METALLOTHIONEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MYC PROTEIN; NERVE CELL ADHESION MOLECULE; NITRIC OXIDE; OROSOMUCOID; PROTEIN C JUN; PROTEIN KINASE C; PROTEIN P53; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE DISMUTASE; UNINDEXED DRUG; UVOMORULIN; VASCULAR ENDOTHELIAL CADHERIN;

EID: 84866309713     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.110.166769     Document Type: Review
Times cited : (216)

References (63)
  • 2
    • 0038121454 scopus 로고    scopus 로고
    • Cadmium nephrotoxicity and evacuation from the body in a rat modeled subchronic intoxication
    • DOI 10.1046/j.1442-2042.2003.00627.x
    • Aoyagi T, Hayakawa K, Miyaji K, Ishikawa H, and Hata M (2003) Cadmium nephrotoxicity and evacuation from the body in a rat modeled subchronic intoxication. Int J Urol 10:332-338. (Pubitemid 36776077)
    • (2003) International Journal of Urology , vol.10 , Issue.6 , pp. 332-338
    • Aoyagi, T.1    Hayakawa, K.2    Miyaji, K.3    Ishikawa, H.4    Hata, M.5
  • 3
    • 17944382034 scopus 로고    scopus 로고
    • Renal dysfunction induced by cadmium: Biomarkers of critical effects
    • Bernard A (2004) Renal dysfunction induced by cadmium: biomarkers of critical effects. Biometals 17:519-523.
    • (2004) Biometals , vol.17 , pp. 519-523
    • Bernard, A.1
  • 4
    • 17444405238 scopus 로고    scopus 로고
    • Molecular and ionic mimicry and the transport of toxic metals
    • DOI 10.1016/j.taap.2004.09.007, Membrane Transporters in Toxicology
    • Bridges CC and Zalups RK (2005) Molecular and ionic mimicry and the transport of toxic metals. Toxicol Appl Pharmacol 204:274-308. (Pubitemid 40545232)
    • (2005) Toxicology and Applied Pharmacology , vol.204 , Issue.3 , pp. 274-308
    • Bridges, C.C.1    Zalups, R.K.2
  • 6
    • 77955573840 scopus 로고    scopus 로고
    • Chronic cadmium exposure induces transcriptional activation of the Wnt pathway and upregulation of epithelial-to-mesenchymal transition markers in mouse kidney
    • Chakraborty PK, Scharner B, Jurasovic J, Messner B, Bernhard D, and Thévenod F (2010) Chronic cadmium exposure induces transcriptional activation of the Wnt pathway and upregulation of epithelial-to-mesenchymal transition markers in mouse kidney. Toxicol Lett 198:69-76.
    • (2010) Toxicol Lett , vol.198 , pp. 69-76
    • Chakraborty, P.K.1    Scharner, B.2    Jurasovic, J.3    Messner, B.4    Bernhard, D.5    Thévenod, F.6
  • 8
    • 84866331376 scopus 로고    scopus 로고
    • Identification of cadmium regulated miRNAs in rat renal proximal tubule epithelial NRK52E cells
    • De La Fuente A, Alt AC, Fay MJ, and Prozialeck WC (2011) Identification of cadmium regulated miRNAs in rat renal proximal tubule epithelial NRK52E cells. In Vitro Cell Dev Biol Anim 47:S31-S32.
    • (2011) In Vitro Cell Dev Biol Anim , vol.47
    • De La Fuente, A.1    Alt, A.C.2    Fay, M.J.3    Prozialeck, W.C.4
  • 10
    • 77955578875 scopus 로고    scopus 로고
    • Mitochondria, reactive oxygen species and cadmium toxicity in the kidney
    • Gobe G and Crane D (2010) Mitochondria, reactive oxygen species and cadmium toxicity in the kidney. Toxicol Lett 198:49-55.
    • (2010) Toxicol Lett , vol.198 , pp. 49-55
    • Gobe, G.1    Crane, D.2
  • 11
    • 0024378832 scopus 로고
    • Non-metallothionein-bound cadmium in the pathogenesis of cadmium nephrotoxicity in the rat
    • DOI 10.1016/0041-008X(89)90272-X
    • Goyer RA, Miller CR, Zhu SY, and Victery W (1989) Non-metallothionein- bound cadmium in the pathogenesis of cadmium nephrotoxicity in the rat. Toxicol Appl Pharmacol 101:232-244. (Pubitemid 20004518)
    • (1989) Toxicology and Applied Pharmacology , vol.101 , Issue.2 , pp. 232-244
    • Goyer, R.A.1    Miller, C.R.2    Zhu, S.-Y.3    Victery, W.4
  • 12
  • 13
    • 39749106821 scopus 로고    scopus 로고
    • Striking association between urinary cadmium level and albuminuria among Torres Strait Islander people with diabetes
    • DOI 10.1016/j.envres.2007.10.004, PII S0013935107002228
    • Haswell-Elkins M, Satarug S, O'Rourke P, Moore M, Ng J, McGrath V, and Walmby M (2008) Striking association between urinary cadmium level and albuminuria among Torres Strait Islander people with diabetes. Environ Res 106:379-383. (Pubitemid 351296206)
    • (2008) Environmental Research , vol.106 , Issue.3 , pp. 379-383
    • Haswell-Elkins, M.1    Satarug, S.2    O'Rourke, P.3    Moore, M.4    Ng, J.5    McGrath, V.6    Walmby, M.7
  • 14
    • 67649663950 scopus 로고    scopus 로고
    • Discovery of ZIP transporters that participate in cadmium damage to testis and kidney
    • He L, Wang B, Hay EB, and Nebert DW (2009) Discovery of ZIP transporters that participate in cadmium damage to testis and kidney. Toxicol Appl Pharmacol 238:250-257.
    • (2009) Toxicol Appl Pharmacol , vol.238 , pp. 250-257
    • He, L.1    Wang, B.2    Hay, E.B.3    Nebert, D.W.4
  • 16
    • 0003633755 scopus 로고    scopus 로고
    • Institute of Laboratory Animal Resources 7th ed, Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council, Washington DC
    • Institute of Laboratory Animal Resources (1996) Guide for the Care and Use of Laboratory Animals, 7th ed, Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council, Washington DC.
    • (1996) Guide for the Care and Use of Laboratory Animals
  • 17
    • 0036225268 scopus 로고    scopus 로고
    • Cadmium overload and toxicity
    • Järup L (2002) Cadmium overload and toxicity. Nephrol Dial Transplant 17 (Suppl 2):35-39.
    • (2002) Nephrol Dial Transplant , vol.17 , Issue.SUPPL. 2 , pp. 35-39
    • Järup, L.1
  • 18
    • 67649654113 scopus 로고    scopus 로고
    • Current status of cadmium as an environmental health problem
    • Järup L and Akesson A (2009) Current status of cadmium as an environmental health problem. Toxicol Appl Pharmacol 238:201-208.
    • (2009) Toxicol Appl Pharmacol , vol.238 , pp. 201-208
    • Järup, L.1    Akesson, A.2
  • 20
    • 0031690143 scopus 로고    scopus 로고
    • Toxicokinetics and biochemistry of cadmium with special emphasis on the role of metallothionein
    • Jin T, Lu J, and Nordberg M (1998) Toxicokinetics and biochemistry of cadmium with special emphasis on the role of metallothionein. Neurotoxicology 19:529-535.
    • (1998) Neurotoxicology , vol.19 , pp. 529-535
    • Jin, T.1    Lu, J.2    Nordberg, M.3
  • 21
    • 67649649748 scopus 로고    scopus 로고
    • Mechanisms of cadmium carcinogenesis
    • Joseph P (2009) Mechanisms of cadmium carcinogenesis. Toxicol Appl Pharmacol 238:272-279.
    • (2009) Toxicol Appl Pharmacol , vol.238 , pp. 272-279
    • Joseph, P.1
  • 22
    • 0030848109 scopus 로고    scopus 로고
    • Role of metallothionein in cadmium-induced hepatotoxicity and nephrotoxicity
    • Klaassen CD and Liu J (1997) Role of metallothionein in cadmium-induced hepatotoxicity and nephrotoxicity. Drug Metab Rev 29:79-102. (Pubitemid 27293603)
    • (1997) Drug Metabolism Reviews , vol.29 , Issue.1-2 , pp. 79-102
    • Klaassen, C.D.1    Liu, J.2
  • 23
  • 24
    • 0032425077 scopus 로고    scopus 로고
    • 2-induced nephrotoxicity indicated that renal injury is not mediated by the CdMT complex
    • DOI 10.1006/toxs.1998.2541
    • Liu J, Liu Y, Habeebu SS, and Klaassen CD (1998) Susceptibility of MT-null mice to chronic CdCl2-induced nephrotoxicity indicates that renal injury is not mediated by the CdMT complex. Toxicol Sci 46:197-203. (Pubitemid 29014098)
    • (1998) Toxicological Sciences , vol.46 , Issue.1 , pp. 197-203
    • Liu, J.1    Liu, Y.2    Habeebu, S.S.3    Klaassen, C.D.4
  • 25
    • 67649641505 scopus 로고    scopus 로고
    • Role of oxidative stress in cadmium toxicity and carcinogenesis
    • Liu J, Qu W, and Kadiiska MB (2009) Role of oxidative stress in cadmium toxicity and carcinogenesis. Toxicol Appl Pharmacol 238:209-214.
    • (2009) Toxicol Appl Pharmacol , vol.238 , pp. 209-214
    • Liu, J.1    Qu, W.2    Kadiiska, M.B.3
  • 27
    • 0033135667 scopus 로고    scopus 로고
    • The role of cell adhesion molecules in ischemic acute renal failure
    • DOI 10.1016/S0002-9343(99)00061-3, PII S0002934399000613
    • Molitoris BA and Marrs J (1999) The role of cell adhesion molecules in ischemic acute renal failure. Am J Med 106:583-592. (Pubitemid 29231111)
    • (1999) American Journal of Medicine , vol.106 , Issue.5 , pp. 583-592
    • Molitoris, B.A.1    Marrs, J.2
  • 28
    • 0027193349 scopus 로고
    • Detecting the renal effects of cadmium toxicity
    • Mueller PW (1993) Detecting the renal effects of cadmium toxicity. Clin Chem 39:743-745.
    • (1993) Clin Chem , vol.39 , pp. 743-745
    • Mueller, P.W.1
  • 29
    • 0031846115 scopus 로고    scopus 로고
    • New approaches for detecting thresholds of human nephrotoxicity using cadmium as an example
    • Mueller PW, Price RG, and Finn WF (1998) New approaches for detecting thresholds of human nephrotoxicity using cadmium as an example. Environ Health Perspect 106:227-230. (Pubitemid 28282500)
    • (1998) Environmental Health Perspectives , vol.106 , Issue.5 , pp. 227-230
    • Mueller, P.W.1    Price, R.G.2    Finn, W.F.3
  • 32
    • 17944365226 scopus 로고    scopus 로고
    • Cadmium and health in the 21st century - Historical remarks and trends for the future
    • Nordberg GF (2004) Cadmium and health in the 21st century - historical remarks and trends for the future. Biometals 17:485-489.
    • (2004) Biometals , vol.17 , pp. 485-489
    • Nordberg, G.F.1
  • 33
    • 84866342199 scopus 로고    scopus 로고
    • Metals and cell adhesion molecules
    • J. Koropatkick and R.K. Zalups eds Taylor and Francis, Oxford, UK
    • Parrish AR and Prozialeck WC (2010) Metals and cell adhesion molecules, in Cellular and Molecular Biology of Metals (J. Koropatkick and R.K. Zalups eds) pp 327-350, Taylor and Francis, Oxford, UK.
    • (2010) Cellular and Molecular Biology of Metals , pp. 327-350
    • Parrish, A.R.1    Prozialeck, W.C.2
  • 34
    • 0034186162 scopus 로고    scopus 로고
    • Evidence that E-cadherin may be a target for cadmium toxicity in epithelial cells
    • Prozialeck WC (2000) Evidence that E-cadherin may be a target for cadmium toxicity in epithelial cells. Toxicol Appl Pharmacol 164:231-249.
    • (2000) Toxicol Appl Pharmacol , vol.164 , pp. 231-249
    • Prozialeck, W.C.1
  • 35
    • 33947673334 scopus 로고    scopus 로고
    • Cell adhesion molecules in chemically-induced renal injury
    • DOI 10.1016/j.pharmthera.2007.01.001, PII S0163725807000149
    • Prozialeck WC and Edwards JR (2007) Cell adhesion molecules in chemically-induced renal injury. Pharmacol Ther 114:74-93. (Pubitemid 46498159)
    • (2007) Pharmacology and Therapeutics , vol.114 , Issue.1 , pp. 74-93
    • Prozialeck, W.C.1    Edwards, J.R.2
  • 36
    • 78349307170 scopus 로고    scopus 로고
    • Early biomarkers of cadmium exposure and nephrotoxicity
    • Prozialeck WC and Edwards JR (2010) Early biomarkers of cadmium exposure and nephrotoxicity. Biometals 23:793-809.
    • (2010) Biometals , vol.23 , pp. 793-809
    • Prozialeck, W.C.1    Edwards, J.R.2
  • 37
    • 67649639427 scopus 로고    scopus 로고
    • Expression of kidney injury molecule-1 (Kim-1) in relation to necrosis and apoptosis during the early stages of Cd-induced proximal tubule injury
    • Prozialeck WC, Edwards JR, Lamar PC, Liu J, Vaidya VS, and Bonventre JV (2009a) Expression of kidney injury molecule-1 (Kim-1) in relation to necrosis and apoptosis during the early stages of Cd-induced proximal tubule injury. Toxicol Appl Pharmacol 238:306-314.
    • (2009) Toxicol Appl Pharmacol , vol.238 , pp. 306-314
    • Prozialeck, W.C.1    Edwards, J.R.2    Lamar, P.C.3    Liu, J.4    Vaidya, V.S.5    Bonventre, J.V.6
  • 40
    • 2942593691 scopus 로고    scopus 로고
    • Differential expression of E-cadherin, N-cadherin and β-catenin in proximal and distal segments of the rat nephron
    • Prozialeck WC, Lamar PC, and Appelt DM (2004) Differential expression of E-cadherin, N-cadherin and β-catenin in proximal and distal segments of the rat nephron. BMC Physiol 4:10.
    • (2004) BMC Physiol , vol.4 , pp. 10
    • Prozialeck, W.C.1    Lamar, P.C.2    Appelt, D.M.3
  • 41
    • 0037603262 scopus 로고    scopus 로고
    • Cadmium alters the localization of N-cadherin, E-cadherin, and β-catenin in the proximal tubule epithelium
    • DOI 10.1016/S0041-008X(03)00130-3
    • Prozialeck WC, Lamar PC, and Lynch SM (2003) Cadmium alters the localization of N-cadherin, E-cadherin, and β-catenin in the proximal tubule epithelium. Toxicol Appl Pharmacol 189:180-195. (Pubitemid 36677530)
    • (2003) Toxicology and Applied Pharmacology , vol.189 , Issue.3 , pp. 180-195
    • Prozialeck, W.C.1    Lamar, P.C.2    Lynch, S.M.3
  • 42
    • 0026357430 scopus 로고
    • 2+-dependent cell-cell junctions and alters the pattern of E-cadherin immunofluorescence in LLC-PK1 cells
    • 2+-dependent cell-cell junctions and alters the pattern of E-cadherin immunofluorescence in LLC-PK1 cells. Biochem Biophys Res Commun 181:1118-1124.
    • (1991) Biochem Biophys Res Commun , vol.181 , pp. 1118-1124
    • Prozialeck, W.C.1    Niewenhuis, R.J.2
  • 45
    • 29244491956 scopus 로고    scopus 로고
    • Loss of basolateral invaginations in proximal tubules of cadmium-intoxicated rats is independent of microtubules and clathrin
    • DOI 10.1016/j.tox.2005.10.009, PII S0300483X0500507X
    • Sabolic I, Herak-Kramberger CM, Antolovic R, Breton S, and Brown D (2006) Loss of basolateral invaginations in proximal tubules of cadmium-intoxicated rats is independent of microtubules and clathrin. Toxicology 218:149-163. (Pubitemid 41821346)
    • (2006) Toxicology , vol.218 , Issue.2-3 , pp. 149-163
    • Sabolic, I.1    Herak-Kramberger, C.M.2    Antolovic, R.3    Breton, S.4    Brown, D.5
  • 46
    • 0035964436 scopus 로고    scopus 로고
    • Subchronic cadmium treatment affects the abundance and arrangement of cytoskeletal proteins in rat renal proximal tubule cells
    • DOI 10.1016/S0300-483X(01)00450-4, PII S0300483X01004504
    • Sabolić I, Herak-Kramberger CM, and Brown D (2001) Subchronic cadmium treatment affects the abundance and arrangement of cytoskeletal proteins in rat renal proximal tubule cells. Toxicology 165:205-216. (Pubitemid 32778313)
    • (2001) Toxicology , vol.165 , Issue.2-3 , pp. 205-216
    • Saboli, I.1    Herak-Kramberger, C.M.2    Brown, D.3
  • 47
    • 12244295161 scopus 로고    scopus 로고
    • A global perspective on cadmium pollution and toxicity in non-occupationally exposed population
    • DOI 10.1016/S0378-4274(02)00381-8, PII S0378427402003818
    • Satarug S, Baker JR, Urbenjapol S, Haswell-Elkins M, Reilly PE, Williams DJ, and Moore MR (2003) A global perspective on cadmium pollution and toxicity in non-occupationally exposed population. Toxicol Lett 137:65-83. (Pubitemid 36050084)
    • (2003) Toxicology Letters , vol.137 , Issue.1-2 , pp. 65-83
    • Satarug, S.1    Baker, J.R.2    Urbenjapol, S.3    Haswell-Elkins, M.4    Reilly, P.E.B.5    Williams, D.J.6    Moore, M.R.7
  • 49
    • 3543105592 scopus 로고    scopus 로고
    • Adverse health effects of chronic exposure to low-level cadmium in foodstuffs and cigarette smoke
    • Satarug S and Moore MR (2004) Adverse health effects of chronic exposure to low-level cadmium in foodstuffs and cigarette smoke. Environ Health Perspect 112:1099-1103. (Pubitemid 39029166)
    • (2004) Environmental Health Perspectives , vol.112 , Issue.10 , pp. 1099-1103
    • Satarug, S.1    Moore, M.R.2
  • 50
    • 0021287994 scopus 로고
    • Intracellular metabolism and effects of circulating cadmium- metallothionein in the kidney
    • Squibb KS and Fowler BA (1984) Intracellular metabolism and effects of circulating cadmium-metallothionein in the kidney. Environ Health Perspect 54:31-35. (Pubitemid 14094102)
    • (1984) Environmental Health Perspectives , vol.VOL. 54 , pp. 31-35
    • Squibb, K.S.1    Fowler, B.A.2
  • 51
    • 77955582755 scopus 로고    scopus 로고
    • Recent applications of benchmark dose method for estimation of reference cadmium exposure for renal effects in man
    • Suwazono Y, Uetani M, Akesson A, and Vahter M (2010) Recent applications of benchmark dose method for estimation of reference cadmium exposure for renal effects in man. Toxicol Lett 198:40-43.
    • (2010) Toxicol Lett , vol.198 , pp. 40-43
    • Suwazono, Y.1    Uetani, M.2    Akesson, A.3    Vahter, M.4
  • 52
    • 0033419263 scopus 로고    scopus 로고
    • 2-exposed rat kidney: Relationship with apoptosis and regeneration
    • DOI 10.1046/j.1440-1827.1999.00833.x
    • Tanimoto A, Hamada T, Higashi K, and Sasaguri Y (1999) Distribution of cadmium and metallothionein in CdCl2-exposed rat kidney: relationship with apoptosis and regeneration. Pathol Int 49:125-132. (Pubitemid 29133471)
    • (1999) Pathology International , vol.49 , Issue.2 , pp. 125-132
    • Tanimoto, A.1    Hamada, T.2    Higashi, K.3    Sasaguri, Y.4
  • 53
    • 0027375432 scopus 로고
    • Cell death and regeneration of renal proximal tubular cells in rats with subchronic cadmium intoxication
    • Tanimoto A, Hamada T, and Koide O (1993) Cell death and regeneration of renal proximal tubular cells in rats with subchronic cadmium intoxication. Toxicol Pathol 21:341-352. (Pubitemid 23326509)
    • (1993) Toxicologic Pathology , vol.21 , Issue.4 , pp. 341-352
    • Tanimoto, A.1    Hamada, T.2    Koide, O.3
  • 54
    • 33947245385 scopus 로고    scopus 로고
    • Monitoring of cadmium toxicity in a Thai population with high-level environmental exposure
    • DOI 10.1016/j.toxlet.2007.01.004, PII S0378427407000318
    • Teeyakasem W, Nishijo M, Honda R, Satarug S, Swaddiwudhipong W, and Ruangyuttikarn W (2007) Monitoring of cadmium toxicity in a Thai population with high-level environmental exposure. Toxicol Lett 169:185-195. (Pubitemid 46436368)
    • (2007) Toxicology Letters , vol.169 , Issue.3 , pp. 185-195
    • Teeyakasem, W.1    Nishijo, M.2    Honda, R.3    Satarug, S.4    Swaddiwudhipong, W.5    Ruangyuttikarn, W.6
  • 55
    • 63049091896 scopus 로고    scopus 로고
    • Cadmium and cellular signaling cascades: To be or not to be?
    • Thévenod F (2009) Cadmium and cellular signaling cascades: to be or not to be? Toxicol Appl Pharmacol 238:221-239.
    • (2009) Toxicol Appl Pharmacol , vol.238 , pp. 221-239
    • Thévenod, F.1
  • 56
    • 77953498502 scopus 로고    scopus 로고
    • The role of Wnt/β-catenin signaling in renal carcinogenesis: Lessons from cadmium toxicity studies
    • Thévenod F and Chakraborty PK (2010) The role of Wnt/β-catenin signaling in renal carcinogenesis: lessons from cadmium toxicity studies. Curr Mol Med 10:387-404.
    • (2010) Curr Mol Med , vol.10 , pp. 387-404
    • Thévenod, F.1    Chakraborty, P.K.2
  • 57
    • 34548329097 scopus 로고    scopus 로고
    • Cadmium induces nuclear translocation of β-catenin and increases expression of c-myc and Abcb1a in kidney proximal tubule cells
    • DOI 10.1007/s10534-006-9044-9
    • Thévenod F, Wolff NA, Bork U, Lee WK, and Abouhamed M (2007) Cadmium induces nuclear translocation of β-catenin and increases expression of c-myc and Abcb1a in kidney proximal tubule cells. Biometals 20:807-820. (Pubitemid 47338486)
    • (2007) BioMetals , vol.20 , Issue.5 , pp. 807-820
    • Thevenod, F.1    Wolff, N.A.2    Bork, U.3    Lee, W.-K.4    Abouhamed, M.5
  • 58
    • 60749102735 scopus 로고    scopus 로고
    • Early kidney damage in a population exposed to cadmium and other heavy metals
    • Thomas LD, Hodgson S, Nieuwenhuijsen M, and Jarup L (2009) Early kidney damage in a population exposed to cadmium and other heavy metals. Environ Health Perspect 117:181-184.
    • (2009) Environ Health Perspect , vol.117 , pp. 181-184
    • Thomas, L.D.1    Hodgson, S.2    Nieuwenhuijsen, M.3    Jarup, L.4
  • 59
    • 2442557303 scopus 로고    scopus 로고
    • The effects of environmental cadmium exposure on kidney function: The possible influence of age
    • DOI 10.1016/j.envres.2003.10.003, PII S0013935103001932
    • Trzcinka-Ochocka M, Jakubowski M, Razniewska G, Halatek T, and Gazewski A (2004) The effects of environmental cadmium exposure on kidney function: the possible influence of age. Environ Res 95:143-150. (Pubitemid 38625890)
    • (2004) Environmental Research , vol.95 , Issue.2 , pp. 143-150
    • Trzcinka-Ochocka, M.1    Jakubowski, M.2    Razniewska, G.3    Halatek, T.4    Gazewski, A.5
  • 61
    • 0345708255 scopus 로고    scopus 로고
    • Cadmium carcinogenesis
    • Waalkes MP (2003) Cadmium carcinogenesis. Mutat Res 533:107-120.
    • (2003) Mutat Res , vol.533 , pp. 107-120
    • Waalkes, M.P.1
  • 62
    • 67649683947 scopus 로고    scopus 로고
    • Pleiotropic effects of cadmium in mesangial cells
    • Xiao W, Liu Y, and Templeton DM (2009) Pleiotropic effects of cadmium in mesangial cells. Toxicol Appl Pharmacol 238:315-326.
    • (2009) Toxicol Appl Pharmacol , vol.238 , pp. 315-326
    • Xiao, W.1    Liu, Y.2    Templeton, D.M.3


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