Cadmium toxicity is caused by accumulation of p53 through the down-regulation of Ube2d family genes in vitro and in vivo

Journal of Toxicological Sciences

Volumn 36, Issue 2, 2011, Pages 191-200

  Tokumoto, Maki ^a,b   Fujiwara, Yasuyuki ^b   Shimada, Akinori ^c   Hasegawa, Tatsuya ^d   Seko, Yoshiyuki ^d   Nagase, Hisamitsu ^a   Satoh, Masahiko ^b  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^b AICHI GAKUIN UNIVERSITY   (Japan)

^c TOTTORI UNIVERSITY   (Japan)

^d YAMANASHI INSTITUTE OF ENVIRONMENTAL SCIENCES   (Japan)

Author keywords

Apoptosis; Cadmium; NRK 52E cells; Renal toxicity; Ube2d

Indexed keywords

BETA ACTIN; CADMIUM; PROTEIN P53; UBIQUITIN CONJUGATING ENZYME; UBIQUITIN CONJUGATING ENZYME E2D1; UBIQUITIN CONJUGATING ENZYME E2D2; UBIQUITIN CONJUGATING ENZYME E2D3; UBIQUITIN CONJUGATING ENZYME E2D4; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL CULTURE; CELL LINE; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; DOWN REGULATION; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; GENE SEQUENCE; IN VITRO STUDY; IN VIVO STUDY; KIDNEY TUBULE CELL; MOUSE; NEPHROTOXICITY; NONHUMAN; PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL; RAT; RNA EXTRACTION; UREA NITROGEN BLOOD LEVEL; WESTERN BLOTTING;

MUS; RATTUS;

EID: 79955403347     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.36.191     Document Type: Article

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