-
2
-
-
78651101592
-
Diabetic neuropathies: Update on definitions diagnostic criteria estimation of severity and treatments
-
Toronto Diabetic Neuropathy Expert Group
-
Tesfaye S, Boulton AJ, Dyck PJ, et al.; Toronto Diabetic Neuropathy Expert Group. Diabetic neuropathies: Update on definitions, diagnostic criteria, estimation of severity, and treatments. Diabetes Care 2010;33:2285-2293
-
(2010)
Diabetes Care
, vol.33
, pp. 2285-2293
-
-
Tesfaye, S.1
Boulton, A.J.2
Dyck, P.J.3
-
3
-
-
33750597534
-
Diabetic retinopathy: Seeing beyond glucose-induced microvascular disease
-
JDRF Diabetic Retinopathy Center Group
-
Antonetti DA, Barber AJ, Bronson SK, et al.; JDRF Diabetic Retinopathy Center Group. Diabetic retinopathy: Seeing beyond glucose-induced microvascular disease. Diabetes 2006;55:2401-2411
-
(2006)
Diabetes
, vol.55
, pp. 2401-2411
-
-
Antonetti, D.A.1
Barber, A.J.2
Bronson, S.K.3
-
7
-
-
0016237093
-
Effect of streptozotocin diabetes and insulin treatment on the rate of protein synthesis in tissues of the rat in vivo
-
Pain VM, Garlick PJ. Effect of streptozotocin diabetes and insulin treatment on the rate of protein synthesis in tissues of the rat in vivo. J Biol Chem 1974; 249:4510-4514
-
(1974)
J Biol Chem
, vol.249
, pp. 4510-4514
-
-
Pain, V.M.1
Garlick, P.J.2
-
8
-
-
70349624471
-
Differential effects of insulin deprivation and systemic insulin treatment on plasma protein synthesis in type 1 diabetic people
-
Jaleel A, Klaus KA, Morse DM, et al. Differential effects of insulin deprivation and systemic insulin treatment on plasma protein synthesis in type 1 diabetic people. Am J Physiol Endocrinol Metab 2009;297:E889-E897
-
(2009)
Am J Physiol Endocrinol Metab
, vol.297
-
-
Jaleel, A.1
Klaus, K.A.2
Morse, D.M.3
-
9
-
-
0026563291
-
Renal hypertrophy in streptozotocin diabetic rats: Role of proteolytic lysosomal enzymes
-
Olbricht CJ, Geissinger B. Renal hypertrophy in streptozotocin diabetic rats: Role of proteolytic lysosomal enzymes. Kidney Int 1992;41:966-972
-
(1992)
Kidney Int
, vol.41
, pp. 966-972
-
-
Olbricht, C.J.1
Geissinger, B.2
-
10
-
-
0015929482
-
Relationship between protein synthesis and RNA content in skeletal muscle
-
Millward DJ, Garlick PJ, James WP, Nnanyelugo DO, Ryatt JS. Relationship between protein synthesis and RNA content in skeletal muscle. Nature 1973;241: 204-205
-
(1973)
Nature
, vol.241
, pp. 204-205
-
-
Millward, D.J.1
Garlick, P.J.2
James, W.P.3
Nnanyelugo, D.O.4
Ryatt, J.S.5
-
11
-
-
0020692026
-
Diabetesinduced alterations in liver protein synthesis. Changes in the relative abundance of mRNAs for albumin and other plasma proteins
-
Jefferson LS, Liao WS, Peavy DE, Miller TB, Appel MC, Taylor JM. Diabetesinduced alterations in liver protein synthesis. Changes in the relative abundance of mRNAs for albumin and other plasma proteins. J Biol Chem 1983;258:1369-1375
-
(1983)
J Biol Chem
, vol.258
, pp. 1369-1375
-
-
Jefferson, L.S.1
Liao, W.S.2
Peavy, D.E.3
Miller, T.B.4
Appel, M.C.5
Taylor, J.M.6
-
12
-
-
0019615048
-
Protein synthesis in liver and small intestine in protein deprivation and diabetes
-
McNurlan MA, Garlick PJ. Protein synthesis in liver and small intestine in protein deprivation and diabetes. Am J Physiol 1981;241:E238-E245
-
(1981)
Am J Physiol
, vol.241
-
-
McNurlan, M.A.1
Garlick, P.J.2
-
13
-
-
80055073635
-
The mechanism of insulinstimulated 4E-BP protein binding to mammalian target of rapamycin (mTOR)complex 1 and its contribution to mTOR complex 1 signaling
-
Rapley J, Oshiro N, Ortiz-Vega S, Avruch J. The mechanism of insulinstimulated 4E-BP protein binding to mammalian target of rapamycin (mTOR)complex 1 and its contribution to mTOR complex 1 signaling. J Biol Chem 2011; 286:38043-38053
-
(2011)
J Biol Chem
, vol.286
, pp. 38043-38053
-
-
Rapley, J.1
Oshiro, N.2
Ortiz-Vega, S.3
Avruch, J.4
-
15
-
-
33745298554
-
Diabetes reduces basal retinal insulin receptor signaling: Reversal with systemic and local insulin
-
Reiter CE, Wu X, Sandirasegarane L, et al. Diabetes reduces basal retinal insulin receptor signaling: Reversal with systemic and local insulin. Diabetes 2006;55:1148-1156
-
(2006)
Diabetes
, vol.55
, pp. 1148-1156
-
-
Reiter, C.E.1
Wu, X.2
Sandirasegarane, L.3
-
16
-
-
80055062104
-
Differential roles of hyperglycemia and hypoinsulinemia in diabetes induced retinal cell death: Evidence for retinal insulin resistance
-
Fort PE, Losiewicz MK, Reiter CE, et al. Differential roles of hyperglycemia and hypoinsulinemia in diabetes induced retinal cell death: Evidence for retinal insulin resistance. PLoS One 2011;6:e26498
-
(2011)
PLoS One
, vol.6
-
-
Fort, P.E.1
Losiewicz, M.K.2
Reiter, C.E.3
-
17
-
-
0142084679
-
Akt promotes increased mammalian cell size by stimulating protein synthesis and inhibiting protein degradation
-
Faridi J, Fawcett J, Wang L, Roth RA. Akt promotes increased mammalian cell size by stimulating protein synthesis and inhibiting protein degradation. Am J Physiol Endocrinol Metab 2003;285:E964-E972
-
(2003)
Am J Physiol Endocrinol Metab
, vol.285
-
-
Faridi, J.1
Fawcett, J.2
Wang, L.3
Roth, R.A.4
-
18
-
-
25644447454
-
Up-regulation of PI3K/Akt signaling by 17beta-estradiol through activation of estrogen receptor-Alpha, but not estrogen receptor-beta, and stimulates cell growth in breast cancer cells
-
Lee YR, Park J, Yu HN, Kim JS, Youn HJ, Jung SH. Up-regulation of PI3K/Akt signaling by 17beta-estradiol through activation of estrogen receptor-Alpha, but not estrogen receptor-beta, and stimulates cell growth in breast cancer cells. Biochem Biophys Res Commun 2005;336:1221-1226
-
(2005)
Biochem Biophys Res Commun
, vol.336
, pp. 1221-1226
-
-
Lee, Y.R.1
Park, J.2
Yu, H.N.3
Kim, J.S.4
Youn, H.J.5
Jung, S.H.6
-
19
-
-
0032529103
-
Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin
-
Barber AJ, Lieth E, Khin SA, Antonetti DA, Buchanan AG, Gardner TW. Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin. J Clin Invest 1998;102:783-791
-
(1998)
J Clin Invest
, vol.102
, pp. 783-791
-
-
Barber, A.J.1
Lieth, E.2
Khin, S.A.3
Antonetti, D.A.4
Buchanan, A.G.5
Gardner, T.W.6
-
20
-
-
0031737671
-
Vascular permeability in experimental diabetes is associated with reduced endothelial occludin content: Vascular endothelial growth factor decreases occludin in retinal endothelial cells
-
Penn State Retina Research Group
-
Antonetti DA, Barber AJ, Khin S, Lieth E, Tarbell JM, Gardner TW; Penn State Retina Research Group. Vascular permeability in experimental diabetes is associated with reduced endothelial occludin content: vascular endothelial growth factor decreases occludin in retinal endothelial cells. Diabetes 1998;47:1953-1959
-
(1998)
Diabetes
, vol.47
, pp. 1953-1959
-
-
Antonetti, D.A.1
Barber, A.J.2
Khin, S.3
Lieth, E.4
Tarbell, J.M.5
Gardner, T.W.6
-
21
-
-
4344573553
-
Death of retinal neurons in streptozotocin-induced diabetic mice
-
Martin PM, Roon P, Van Ells TK, Ganapathy V, Smith SB. Death of retinal neurons in streptozotocin-induced diabetic mice. Invest Ophthalmol Vis Sci 2004; 45:3330-3336
-
(2004)
Invest Ophthalmol Vis Sci
, vol.45
, pp. 3330-3336
-
-
Martin, P.M.1
Roon, P.2
Van Ells, T.K.3
Ganapathy, V.4
Smith, S.B.5
-
22
-
-
0141594635
-
Apoptotic death of photoreceptors in the streptozotocin-induced diabetic rat retina
-
Park SH, Park JW, Park SJ, et al. Apoptotic death of photoreceptors in the streptozotocin-induced diabetic rat retina. Diabetologia 2003;46:1260-1268
-
(2003)
Diabetologia
, vol.46
, pp. 1260-1268
-
-
Park, S.H.1
Park, J.W.2
Park, S.J.3
-
23
-
-
0038555740
-
Functions of insulin and insulin receptor signaling in retina: Possible implications for diabetic retinopathy
-
Reiter CE, Gardner TW. Functions of insulin and insulin receptor signaling in retina: Possible implications for diabetic retinopathy. Prog Retin Eye Res 2003;22:545-562
-
(2003)
Prog Retin Eye Res
, vol.22
, pp. 545-562
-
-
Reiter, C.E.1
Gardner, T.W.2
-
24
-
-
0032953155
-
Regulation of protein synthesis after acute resistance exercise in diabetic rats
-
Farrell PA, Fedele MJ, Vary TC, Kimball SR, Lang CH, Jefferson LS. Regulation of protein synthesis after acute resistance exercise in diabetic rats. Am J Physiol 1999;276:E721-E727
-
(1999)
Am J Physiol
, vol.276
-
-
Farrell, P.A.1
Fedele, M.J.2
Vary, T.C.3
Kimball, S.R.4
Lang, C.H.5
Jefferson, L.S.6
-
25
-
-
0019214262
-
3H]phenylalanine
-
Garlick PJ, McNurlan MA, Preedy VR. A rapid and convenient technique for measuring the rate of protein synthesis in tissues by injection of [3H]phenylalanine. Biochem J 1980;192:719-723
-
(1980)
Biochem J
, vol.192
, pp. 719-723
-
-
Garlick, P.J.1
McNurlan, M.A.2
Preedy, V.R.3
-
26
-
-
80054788049
-
Diabetes impairs the neuroprotective properties of retinal alpha-crystallins
-
Losiewicz MK, Fort PE. Diabetes impairs the neuroprotective properties of retinal alpha-crystallins. Invest Ophthalmol Vis Sci 2011;52:5034-5042
-
(2011)
Invest Ophthalmol Vis Sci
, vol.52
, pp. 5034-5042
-
-
Losiewicz, M.K.1
Fort, P.E.2
-
27
-
-
21244458013
-
Structure of S6 kinase 1 determines whether raptormTOR or rictor-mTOR phosphorylates its hydrophobic motif site
-
Ali SM, Sabatini DM. Structure of S6 kinase 1 determines whether raptormTOR or rictor-mTOR phosphorylates its hydrophobic motif site. J Biol Chem 2005; 280:19445-19448
-
(2005)
J Biol Chem
, vol.280
, pp. 19445-19448
-
-
Ali, S.M.1
Sabatini, D.M.2
-
28
-
-
0032081552
-
Protein turnover in skeletal muscle of the diabetic rat: Activation of ubiquitin-dependent proteolysis
-
Rodríguez T, Busquets S, Alvarez B, et al. Protein turnover in skeletal muscle of the diabetic rat: Activation of ubiquitin-dependent proteolysis. Int J Mol Med 1998;1:971-977
-
(1998)
Int J Mol Med
, vol.1
, pp. 971-977
-
-
Rodríguez, T.1
Busquets, S.2
Alvarez, B.3
-
29
-
-
0025903616
-
Effect of diabetes and insulin treatment of diabetic rats on total RNA, poly(A)+ RNA, and mRNA in skeletal muscle
-
Kent JD, Kimball SR, Jefferson LS. Effect of diabetes and insulin treatment of diabetic rats on total RNA, poly(A)+ RNA, and mRNA in skeletal muscle. Am J Physiol 1991;260:C409-C416
-
(1991)
Am J Physiol
, vol.260
-
-
Kent, J.D.1
Kimball, S.R.2
Jefferson, L.S.3
-
30
-
-
66149122699
-
The retinal proteome in experimental diabetic retinopathy: Up-regulation of crystallins and reversal by systemic and periocular insulin
-
Fort PE, Freeman WM, Losiewicz MK, Singh RS, Gardner TW. The retinal proteome in experimental diabetic retinopathy: Up-regulation of crystallins and reversal by systemic and periocular insulin. Mol Cell Proteomics 2009;8:767-779
-
(2009)
Mol Cell Proteomics
, vol.8
, pp. 767-779
-
-
Fort, P.E.1
Freeman, W.M.2
Losiewicz, M.K.3
Singh, R.S.4
Gardner, T.W.5
-
31
-
-
54049107380
-
Diabetes downregulates presynaptic proteins and reduces basal synapsin i phosphorylation in rat retina
-
VanGuilder HD, Brucklacher RM, Patel K, Ellis RW, Freeman WM, Barber AJ. Diabetes downregulates presynaptic proteins and reduces basal synapsin I phosphorylation in rat retina. Eur J Neurosci 2008;28:1-11
-
(2008)
Eur J Neurosci
, vol.28
, pp. 1-11
-
-
Vanguilder, H.D.1
Brucklacher, R.M.2
Patel, K.3
Ellis, R.W.4
Freeman, W.M.5
Barber, A.J.6
-
32
-
-
0036230645
-
Orally administered leucine enhances protein synthesis in skeletal muscle of diabetic rats in the absence of increases in 4E-BP1 or S6K1 phosphorylation
-
Anthony JC, Reiter AK, Anthony TG, et al. Orally administered leucine enhances protein synthesis in skeletal muscle of diabetic rats in the absence of increases in 4E-BP1 or S6K1 phosphorylation. Diabetes 2002;51:928-936
-
(2002)
Diabetes
, vol.51
, pp. 928-936
-
-
Anthony, J.C.1
Reiter, A.K.2
Anthony, T.G.3
-
33
-
-
48349096394
-
Activation of the mammalian target of rapamycin complex 1 is both necessary and sufficient to stimulate eukaryotic initiation factor 2Bvarepsilon mRNA translation and protein synthesis
-
Kubica N, Crispino JL, Gallagher JW, Kimball SR, Jefferson LS. Activation of the mammalian target of rapamycin complex 1 is both necessary and sufficient to stimulate eukaryotic initiation factor 2Bvarepsilon mRNA translation and protein synthesis. Int J Biochem Cell Biol 2008;40:2522-2533
-
(2008)
Int J Biochem Cell Biol
, vol.40
, pp. 2522-2533
-
-
Kubica, N.1
Crispino, J.L.2
Gallagher, J.W.3
Kimball, S.R.4
Jefferson, L.S.5
-
34
-
-
84871194183
-
Deletion of rictor in neural progenitor cells reveals contributions of mTORC2 signaling to tuberous sclerosis complex
-
Carson RP, Fu C, Winzenburger P, Ess KC. Deletion of rictor in neural progenitor cells reveals contributions of mTORC2 signaling to tuberous sclerosis complex. Hum Mol Genet 2013;22:140-152
-
(2013)
Hum Mol Genet
, vol.22
, pp. 140-152
-
-
Carson, R.P.1
Fu, C.2
Winzenburger, P.3
Ess, K.C.4
-
35
-
-
84865761062
-
Mammalian target of rapamycin complex 1 (mTORC1) and 2 (mTORC2) control the dendritic arbor morphology of hippocampal neurons
-
Urbanska M, Gozdz A, Swiech LJ, Jaworski J. Mammalian target of rapamycin complex 1 (mTORC1) and 2 (mTORC2) control the dendritic arbor morphology of hippocampal neurons. J Biol Chem 2012;287:30240-30256
-
(2012)
J Biol Chem
, vol.287
, pp. 30240-30256
-
-
Urbanska, M.1
Gozdz, A.2
Swiech, L.J.3
Jaworski, J.4
-
36
-
-
0019720766
-
Impairment of protein synthesis in the retinal tissue in diabetic rabbits: Secondary reduction of fast axonal transport
-
Chihara E. Impairment of protein synthesis in the retinal tissue in diabetic rabbits: Secondary reduction of fast axonal transport. J Neurochem 1981;37: 247-250
-
(1981)
J Neurochem
, vol.37
, pp. 247-250
-
-
Chihara, E.1
-
37
-
-
0019934627
-
Reduced protein synthesis in diabetic retina and secondary reduction of slow axonal transport
-
Chihara E, Sakugawa M, Entani S. Reduced protein synthesis in diabetic retina and secondary reduction of slow axonal transport. Brain Res 1982;250: 363-366
-
(1982)
Brain Res
, vol.250
, pp. 363-366
-
-
Chihara, E.1
Sakugawa, M.2
Entani, S.3
-
38
-
-
0035941260
-
Excessive hexosamines block the neuroprotective effect of insulin and induce apoptosis in retinal neurons
-
Nakamura M, Barber AJ, Antonetti DA, et al. Excessive hexosamines block the neuroprotective effect of insulin and induce apoptosis in retinal neurons. J Biol Chem 2001;276:43748-43755
-
(2001)
J Biol Chem
, vol.276
, pp. 43748-43755
-
-
Nakamura, M.1
Barber, A.J.2
Antonetti, D.A.3
-
39
-
-
33748596068
-
A multifocal electroretinogram model predicting the development of diabetic retinopathy
-
Bearse MA Jr, Adams AJ, Han Y, et al. A multifocal electroretinogram model predicting the development of diabetic retinopathy. Prog Retin Eye Res 2006;25: 425-448
-
(2006)
Prog Retin Eye Res
, vol.25
, pp. 425-448
-
-
Bearse, Jr.M.A.1
Adams, A.J.2
Han, Y.3
-
40
-
-
84860221553
-
Inner retinal visual dysfunction is a sensitive marker of non-proliferative diabetic retinopathy
-
Jackson GR, Scott IU, Quillen DA, Walter LE, Gardner TW. Inner retinal visual dysfunction is a sensitive marker of non-proliferative diabetic retinopathy. Br J Ophthalmol 2012;96:699-703
-
(2012)
Br J Ophthalmol
, vol.96
, pp. 699-703
-
-
Jackson, G.R.1
Scott, I.U.2
Quillen, D.A.3
Walter, L.E.4
Gardner, T.W.5
-
41
-
-
0027293830
-
Retinal nerve fiber layer defect as an early manifestation of diabetic retinopathy
-
Chihara E, Matsuoka T, Ogura Y, Matsumura M. Retinal nerve fiber layer defect as an early manifestation of diabetic retinopathy. Ophthalmology 1993; 100:1147-1151
-
(1993)
Ophthalmology
, vol.100
, pp. 1147-1151
-
-
Chihara, E.1
Matsuoka, T.2
Ogura, Y.3
Matsumura, M.4
-
42
-
-
12944326259
-
Why cotton wool spots should not be regarded as retinal nerve fibre layer infarcts
-
McLeod D. Why cotton wool spots should not be regarded as retinal nerve fibre layer infarcts. Br J Ophthalmol 2005;89:229-237
-
(2005)
Br J Ophthalmol
, vol.89
, pp. 229-237
-
-
McLeod, D.1
-
43
-
-
0032486268
-
Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism
-
Hara K, Yonezawa K, Weng QP, Kozlowski MT, Belham C, Avruch J. Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism. J Biol Chem 1998;273:14484-14494
-
(1998)
J Biol Chem
, vol.273
, pp. 14484-14494
-
-
Hara, K.1
Yonezawa, K.2
Weng, Q.P.3
Kozlowski, M.T.4
Belham, C.5
Avruch, J.6
-
44
-
-
84875586101
-
Advances in our understanding of diabetic retinopathy
-
Stitt AW, Lois N, Medina RJ, Adamson P, Curtis TM. Advances in our understanding of diabetic retinopathy. Clin Sci (Lond) 2013;125:1-17
-
(2013)
Clin Sci (Lond)
, vol.125
, pp. 1-17
-
-
Stitt, A.W.1
Lois, N.2
Medina, R.J.3
Adamson, P.4
Curtis, T.M.5
-
45
-
-
0035651021
-
Tissue-specific regulation of mitochondrial and cytoplasmic protein synthesis rates by insulin
-
Boirie Y, Short KR, Ahlman B, Charlton M, Nair KS. Tissue-specific regulation of mitochondrial and cytoplasmic protein synthesis rates by insulin. Diabetes 2001;50:2652-2658
-
(2001)
Diabetes
, vol.50
, pp. 2652-2658
-
-
Boirie, Y.1
Short, K.R.2
Ahlman, B.3
Charlton, M.4
Nair, K.S.5
-
46
-
-
58149141478
-
Stimulation of the insulin/mTOR pathway delays cone death in a mouse model of retinitis pigmentosa
-
Punzo C, Kornacker K, Cepko CL. Stimulation of the insulin/mTOR pathway delays cone death in a mouse model of retinitis pigmentosa. Nat Neurosci 2009; 12:44-52
-
(2009)
Nat Neurosci
, vol.12
, pp. 44-52
-
-
Punzo, C.1
Kornacker, K.2
Cepko, C.L.3
-
47
-
-
61349141302
-
Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2
-
Feldman ME, Apsel B, Uotila A, et al. Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2. PLoS Biol 2009; 7:e38
-
(2009)
PLoS Biol
, vol.7
-
-
Feldman, M.E.1
Apsel, B.2
Uotila, A.3
-
48
-
-
84879694703
-
Stabilization of HIF-2a through redox regulation of mTORC2 activation and initiation of mRNA translation
-
Nayak BK, Feliers D, Sudarshan S, et al. Stabilization of HIF-2a through redox regulation of mTORC2 activation and initiation of mRNA translation. Oncogene 2013;32:3147-3155
-
(2013)
Oncogene
, vol.32
, pp. 3147-3155
-
-
Nayak, B.K.1
Feliers, D.2
Sudarshan, S.3
-
49
-
-
20044382806
-
Role for Akt3/protein kinase Bgamma in attainment of normal brain size
-
Easton RM, Cho H, Roovers K, et al. Role for Akt3/protein kinase Bgamma in attainment of normal brain size. Mol Cell Biol 2005;25:1869-1878
-
(2005)
Mol Cell Biol
, vol.25
, pp. 1869-1878
-
-
Easton, R.M.1
Cho, H.2
Roovers, K.3
-
50
-
-
12144254738
-
Axonal protein synthesis and degradation are necessary for efficient growth cone regeneration
-
Verma P, Chierzi S, Codd A, et al. Axonal protein synthesis and degradation are necessary for efficient growth cone regeneration. J Neurosci 2005;25:331-342
-
(2005)
J Neurosci
, vol.25
, pp. 331-342
-
-
Verma, P.1
Chierzi, S.2
Codd, A.3
|