-
1
-
-
84892378119
-
Therapeutic targeting of platelet-derived growth factor receptors in solid tumors
-
Ehnman M, Ostman A. Therapeutic targeting of platelet-derived growth factor receptors in solid tumors. Expert Opin. Investig. Drugs 23(2), 211-226 (2013
-
(2013)
Expert Opin. Investig. Drugs
, vol.23
, Issue.2
, pp. 211-226
-
-
Ehnman, M.1
Ostman, A.2
-
2
-
-
84881023665
-
Multifarious functions of PDGFs and PDGFRs in tumor growth and metastasis
-
Cao Y. Multifarious functions of PDGFs and PDGFRs in tumor growth and metastasis. Trends Mol. Med. 19(8), 460-473 (2013
-
(2013)
Trends Mol. Med
, vol.19
, Issue.8
, pp. 460-473
-
-
Cao, Y.1
-
3
-
-
84890467312
-
Targeting the PDGF signaling pathway in tumor treatment
-
Heldin CH. Targeting the PDGF signaling pathway in tumor treatment. Cell Commun. Signal. 11, 97 (2013
-
(2013)
Cell Commun. Signal
, vol.11
, pp. 97
-
-
Heldin, C.H.1
-
4
-
-
26444481568
-
Sequence survey of receptor tyrosine kinases reveals mutations in glioblastomas
-
Rand V, Huang J, Stockwell T et al. Sequence survey of receptor tyrosine kinases reveals mutations in glioblastomas. Proc. Natl Acad. Sci. USA 102(40), 14344-14349 (2005
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, Issue.40
, pp. 14344-14349
-
-
Rand, V.1
Huang, J.2
Stockwell, T.3
-
5
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
-
Verhaak RG, Hoadley KA, Purdom E et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 17(1), 98-110 (2010
-
(2010)
Cancer Cell
, vol.17
, Issue.1
, pp. 98-110
-
-
Verhaak, R.G.1
Hoadley, K.A.2
Purdom, E.3
-
6
-
-
23944476156
-
PDGFRA mutations in gastrointestinal stromal tumors: Frequency, spectrum and in vitro sensitivity to imatinib
-
Corless CL, Schroeder A, Griffith D et al. PDGFRA mutations in gastrointestinal stromal tumors: frequency, spectrum and in vitro sensitivity to imatinib. J. Clin. Oncol. 23(23), 5357-5364 (2005
-
(2005)
J. Clin. Oncol
, vol.23
, Issue.23
, pp. 5357-5364
-
-
Corless, C.L.1
Schroeder, A.2
Griffith, D.3
-
7
-
-
0642368571
-
Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor
-
Heinrich MC, Corless CL, Demetri GD et al. Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor. J. Clin. Oncol. 21(23), 4342-4349 (2003
-
(2003)
J. Clin. Oncol
, vol.21
, Issue.23
, pp. 4342-4349
-
-
Heinrich, M.C.1
Corless, C.L.2
Demetri, G.D.3
-
8
-
-
0033178762
-
The dermatofibrosarcoma protuberans-associated collagen type Ialpha1/platelet-derived growth factor (PDGF) B-chain fusion gene generates a transforming protein that is processed to functional PDGF-BB
-
Shimizu A, O'brien KP, Sjoblom T et al. The dermatofibrosarcoma protuberans-associated collagen type Ialpha1/platelet-derived growth factor (PDGF) B-chain fusion gene generates a transforming protein that is processed to functional PDGF-BB. Cancer Res. 59(15), 3719-3723 (1999
-
(1999)
Cancer Res
, vol.59
, Issue.15
, pp. 3719-3723
-
-
Shimizu, A.1
O'brien, K.P.2
Sjoblom, T.3
-
9
-
-
0031012850
-
Deregulation of the platelet-derived growth factor B-chain gene via fusion with collagen gene COL1A1 in dermatofibrosarcoma protuberans and giant-cell fibroblastoma
-
Simon MP, Pedeutour F, Sirvent N et al. Deregulation of the platelet-derived growth factor B-chain gene via fusion with collagen gene COL1A1 in dermatofibrosarcoma protuberans and giant-cell fibroblastoma. Nat. Genet. 15(1), 95-98 (1997
-
(1997)
Nat. Genet
, vol.15
, Issue.1
, pp. 95-98
-
-
Simon, M.P.1
Pedeutour, F.2
Sirvent, N.3
-
10
-
-
0027365546
-
Expression and prognostic significance of platelet-derived growth factor and its receptors in epithelial ovarian neoplasms
-
Henriksen R, Funa K, Wilander E, Backstrom T, Ridderheim M, Oberg K. Expression and prognostic significance of platelet-derived growth factor and its receptors in epithelial ovarian neoplasms. Cancer Res. 53(19), 4550-4554 (1993
-
(1993)
Cancer Res
, vol.53
, Issue.19
, pp. 4550-4554
-
-
Henriksen, R.1
Funa, K.2
Wilander, E.3
Backstrom, T.4
Ridderheim, M.5
Oberg, K.6
-
11
-
-
83055181566
-
Clinically relevant biomarkers to select patients for targeted inhibitor therapy after resection of hepatocellular carcinoma
-
Patel SH, Kneuertz PJ, Delgado M et al. Clinically relevant biomarkers to select patients for targeted inhibitor therapy after resection of hepatocellular carcinoma. Ann. Surg. Oncol. 18(12), 3384-3390 (2011
-
(2011)
Ann. Surg. Oncol
, vol.18
, Issue.12
, pp. 3384-3390
-
-
Patel, S.H.1
Kneuertz, P.J.2
Delgado, M.3
-
12
-
-
84857527038
-
Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas
-
Puget S, Philippe C, Bax DA et al. Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas. PLoS ONE 7(2), e30313 (2012
-
(2012)
PLoS ONE
, vol.7
, Issue.2
-
-
Puget, S.1
Philippe, C.2
Bax, D.A.3
-
13
-
-
84886028950
-
Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas
-
Paugh BS, Zhu X, Qu C et al. Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas. Cancer Res. 73(20), 6219-6229 (2013
-
(2013)
Cancer Res
, vol.73
, Issue.20
, pp. 6219-6229
-
-
Paugh, B.S.1
Zhu, X.2
Qu, C.3
-
14
-
-
0028224348
-
Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation
-
Golub TR, Barker GF, Lovett M, Gilliland DG. Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation. Cell 77(2), 307-316 (1994
-
(1994)
Cell
, vol.77
, Issue.2
, pp. 307-316
-
-
Golub, T.R.1
Barker, G.F.2
Lovett, M.3
Gilliland, D.G.4
-
15
-
-
0344987881
-
A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome
-
Cools J, Deangelo DJ, Gotlib J et al. A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome. N. Engl. J. Med. 348(13), 1201-1214 (2003
-
(2003)
N. Engl. J. Med
, vol.348
, Issue.13
, pp. 1201-1214
-
-
Cools, J.1
Deangelo, D.J.2
Gotlib, J.3
-
16
-
-
47949114797
-
Fibroblast growth factor receptor and platelet-derived growth factor receptor abnormalities in eosinophilic myeloproliferative disorders
-
Cross NC, Reiter A. Fibroblast growth factor receptor and platelet-derived growth factor receptor abnormalities in eosinophilic myeloproliferative disorders. Acta Haematol. 119(4), 199-206 (2008
-
(2008)
Acta Haematol
, vol.119
, Issue.4
, pp. 199-206
-
-
Cross, N.C.1
Reiter, A.2
-
17
-
-
84877028141
-
Comprehensive molecular portraits of human breast tumours
-
Cancer Genome Atlas Network
-
Cancer Genome Atlas Network. Comprehensive molecular portraits of human breast tumours. Nature 490(7418), 61-70 (2012
-
(2012)
Nature
, vol.490
, Issue.7418
, pp. 61-70
-
-
-
18
-
-
84866894408
-
Comprehensive genomic characterization of squamous cell lung cancers
-
Cancer Genome Atlas Research Network
-
Cancer Genome Atlas Research Network. Comprehensive genomic characterization of squamous cell lung cancers. Nature 489(7417), 519-525 (2012
-
(2012)
Nature
, vol.489
, Issue.7417
, pp. 519-525
-
-
-
19
-
-
78650303507
-
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
-
Nazarian R, Shi H, Wang Q et al. Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation. Nature 468(7326), 973-977 (2010
-
(2010)
Nature
, vol.468
, Issue.7326
, pp. 973-977
-
-
Nazarian, R.1
Shi, H.2
Wang, Q.3
-
20
-
-
84859765844
-
Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer
-
Duncan JS, Whittle MC, Nakamura K et al. Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer. Cell 149(2), 307-321 (2012
-
(2012)
Cell
, vol.149
, Issue.2
, pp. 307-321
-
-
Duncan, J.S.1
Whittle, M.C.2
Nakamura, K.3
-
21
-
-
0026772431
-
Platelet-derived growth factor and its receptors in human glioma tissue: Expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops
-
Hermanson M, Funa K, Hartman M et al. Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops. Cancer Res. 52(11), 3213-3219 (1992
-
(1992)
Cancer Res
, vol.52
, Issue.11
, pp. 3213-3219
-
-
Hermanson, M.1
Funa, K.2
Hartman, M.3
-
22
-
-
84859893643
-
PDGF and PDGF receptors in glioma
-
Nazarenko I, Hede SM, He X et al. PDGF and PDGF receptors in glioma. Ups J. Med. Sci. 117(2), 99-112 (2012
-
(2012)
Ups J. Med. Sci
, vol.117
, Issue.2
, pp. 99-112
-
-
Nazarenko, I.1
Hede, S.M.2
He, X.3
-
23
-
-
26044467362
-
Amplification of genes encoding KIT PDGFRalpha and VEGFR2 receptor tyrosine kinases is frequent in glioblastoma multiforme
-
Joensuu H, Puputti M, Sihto H, Tynninen O, Nupponen NN. Amplification of genes encoding KIT, PDGFRalpha and VEGFR2 receptor tyrosine kinases is frequent in glioblastoma multiforme. J. Pathol. 207(2), 224-231 (2005
-
(2005)
J. Pathol
, vol.207
, Issue.2
, pp. 224-231
-
-
Joensuu, H.1
Puputti, M.2
Sihto, H.3
Tynninen, O.4
Nupponen, N.N.5
-
24
-
-
84855913314
-
Diffuse intrinsic pontine gliomas: A systematic update on clinical trials and biology
-
Jansen MH, Van Vuurden DG, Vandertop WP, Kaspers GJ. Diffuse intrinsic pontine gliomas: a systematic update on clinical trials and biology. Cancer Treat. Rev. 38(1), 27-35 (2012
-
(2012)
Cancer Treat. Rev
, vol.38
, Issue.1
, pp. 27-35
-
-
Jansen, M.H.1
Van Vuurden, D.G.2
Vandertop, W.P.3
Kaspers, G.J.4
-
25
-
-
77954596239
-
Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease
-
Paugh BS, Qu C, Jones C et al. Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease. J. Clin. Oncol. 28(18), 3061-3068 (2010
-
(2010)
J. Clin. Oncol
, vol.28
, Issue.18
, pp. 3061-3068
-
-
Paugh, B.S.1
Qu, C.2
Jones, C.3
-
26
-
-
0035421175
-
Growth inhibition of dermatofibrosarcoma protuberans tumors by the platelet-derived growth factor receptor antagonist STI571 through induction of apoptosis
-
Sjoblom T, Shimizu A, O'brien KP et al. Growth inhibition of dermatofibrosarcoma protuberans tumors by the platelet-derived growth factor receptor antagonist STI571 through induction of apoptosis. Cancer Res. 61(15), 5778-5783 (2001
-
(2001)
Cancer Res
, vol.61
, Issue.15
, pp. 5778-5783
-
-
Sjoblom, T.1
Shimizu, A.2
O'brien, K.P.3
-
27
-
-
84862117864
-
Dermatofibrosarcoma protruberans treatment with platelet-derived growth factor receptor inhibitor: A review of clinical trial results
-
Malhotra B, Schuetze SM. Dermatofibrosarcoma protruberans treatment with platelet-derived growth factor receptor inhibitor: a review of clinical trial results. Curr. Opin. Oncol. 24(4), 419-424 (2012
-
(2012)
Curr. Opin. Oncol
, vol.24
, Issue.4
, pp. 419-424
-
-
Malhotra, B.1
Schuetze, S.M.2
-
28
-
-
53249152139
-
Activity of dasatinib a dual SRC/ABL kinase inhibitor and IPI-504 a heat shock protein inhibitor, against gastrointestinal stromal tumor-associated PDGFRAD842V mutation
-
Dewaele B, Wasag B, Cools J et al. Activity of dasatinib, a dual SRC/ABL kinase inhibitor, and IPI-504, a heat shock protein inhibitor, against gastrointestinal stromal tumor-associated PDGFRAD842V mutation. Clin. Cancer Res. 14(18), 5749-5758 (2008
-
(2008)
Clin. Cancer Res.
, vol.14
, Issue.18
, pp. 5749-5758
-
-
Dewaele, B.1
Wasag, B.2
Cools, J.3
-
29
-
-
84906557982
-
-
Phase II Study of Crenolanib (CP-868 596), for the Treatment of Patients With Advanced Gastrointestinal Stromal Tumors With the D842-related Mutations and Deletions in the PDGFRA Gene
-
Phase II Study of Crenolanib (CP-868,596), for the Treatment of Patients With Advanced Gastrointestinal Stromal Tumors With the D842-related Mutations and Deletions in the PDGFRA Gene. www.clinicaltrials.gov/ct2/show/NCT01243346
-
-
-
-
30
-
-
84906557975
-
-
ClinicalTrials.gov
-
ClinicalTrials.gov www.clinicaltrials.gov/ct2/results?term= dasatinib+AND+GIST&Search=Search
-
-
-
-
31
-
-
0035242001
-
PDGF-C is an EWS/FLI induced transforming growth factor in Ewing family tumors
-
Zwerner JP, May WA. PDGF-C is an EWS/FLI induced transforming growth factor in Ewing family tumors. Oncogene 20(5), 626-633 (2001
-
(2001)
Oncogene
, vol.20
, Issue.5
, pp. 626-633
-
-
Zwerner, J.P.1
May, W.A.2
-
32
-
-
84863748866
-
PAX3/FOXO1 fusion gene status is the key prognostic molecular marker in rhabdomyosarcoma and significantly improves current risk stratification
-
Missiaglia E, Williamson D, Chisholm J et al. PAX3/FOXO1 fusion gene status is the key prognostic molecular marker in rhabdomyosarcoma and significantly improves current risk stratification. J. Clin. Oncol. 30(14), 1670-1677 (2012
-
(2012)
J. Clin. Oncol
, vol.30
, Issue.14
, pp. 1670-1677
-
-
Missiaglia, E.1
Williamson, D.2
Chisholm, J.3
-
33
-
-
55249083566
-
PDGFR-A is a therapeutic target in alveolar rhabdomyosarcoma
-
Taniguchi E, Nishijo K, Mccleish AT et al. PDGFR-A is a therapeutic target in alveolar rhabdomyosarcoma. Oncogene 27(51), 6550-6560 (2008
-
(2008)
Oncogene
, vol.27
, Issue.51
, pp. 6550-6560
-
-
Taniguchi, E.1
Nishijo, K.2
Mc Cleish, A.T.3
-
34
-
-
0037198637
-
Dominant negative PDGF-C inhibits growth of Ewing family tumor cell lines
-
Zwerner JP, May WA. Dominant negative PDGF-C inhibits growth of Ewing family tumor cell lines. Oncogene 21(24), 3847-3854 (2002
-
(2002)
Oncogene
, vol.21
, Issue.24
, pp. 3847-3854
-
-
Zwerner, J.P.1
May, W.A.2
-
35
-
-
0037994344
-
Beta-platelet-derived growth factor receptor mediates motility and growth of Ewing's sarcoma cells
-
Uren A, Merchant MS, Sun CJ et al. Beta-platelet-derived growth factor receptor mediates motility and growth of Ewing's sarcoma cells. Oncogene 22(15), 2334-2342 (2003
-
(2003)
Oncogene
, vol.22
, Issue.15
, pp. 2334-2342
-
-
Uren, A.1
Merchant, M.S.2
Sun, C.J.3
-
36
-
-
47049107160
-
Stromal cell-derived factor-1 stimulates vasculogenesis and enhances Ewing's sarcoma tumor growth in the absence of vascular endothelial growth factor
-
Reddy K, Zhou Z, Jia SF et al. Stromal cell-derived factor-1 stimulates vasculogenesis and enhances Ewing's sarcoma tumor growth in the absence of vascular endothelial growth factor. Int. J. Cancer 123(4), 831-837 (2008
-
(2008)
Int. J. Cancer
, vol.123
, Issue.4
, pp. 831-837
-
-
Reddy, K.1
Zhou, Z.2
Jia, S.F.3
-
37
-
-
79961230399
-
Pericytes: Developmental, physiological, and pathological perspectives, problems, and promises
-
Armulik A, Genove G, Betsholtz C. Pericytes: developmental, physiological, and pathological perspectives, problems, and promises. Dev. Cell 21(2), 193-215 (2011
-
(2011)
Dev. Cell
, vol.21
, Issue.2
, pp. 193-215
-
-
Armulik, A.1
Genove, G.2
Betsholtz, C.3
-
38
-
-
0027744498
-
Microvascular pericytes express platelet-derived growth factor-beta receptors in human healing wounds and colorectal adenocarcinoma
-
Sundberg C, Ljungstrom M, Lindmark G, Gerdin B, Rubin K. Microvascular pericytes express platelet-derived growth factor-beta receptors in human healing wounds and colorectal adenocarcinoma. Am. J. Pathol. 143(5), 1377-1388 (1993
-
(1993)
Am. J. Pathol
, vol.143
, Issue.5
, pp. 1377-1388
-
-
Sundberg, C.1
Ljungstrom, M.2
Lindmark, G.3
Gerdin, B.4
Rubin, K.5
-
39
-
-
0345798150
-
Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors
-
Abramsson A, Lindblom P, Betsholtz C. Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors. J. Clin. Invest. 112(8), 1142-1151 (2003
-
(2003)
J. Clin. Invest
, vol.112
, Issue.8
, pp. 1142-1151
-
-
Abramsson, A.1
Lindblom, P.2
Betsholtz, C.3
-
40
-
-
16544382996
-
Platelet-derived growth factor production by B16 melanoma cells leads to increased pericyte abundance in tumors and an associated increase in tumor growth rate
-
Furuhashi M, Sjoblom T, Abramsson A et al. Platelet-derived growth factor production by B16 melanoma cells leads to increased pericyte abundance in tumors and an associated increase in tumor growth rate. Cancer Res. 64(8), 2725-2733 (2004
-
(2004)
Cancer Res
, vol.64
, Issue.8
, pp. 2725-2733
-
-
Furuhashi, M.1
Sjoblom, T.2
Abramsson, A.3
-
41
-
-
0038476608
-
Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors
-
Bergers G, Song S, Meyer-Morse N, Bergsland E, Hanahan D. Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors. J. Clin. Invest. 111(9), 1287-1295 (2003
-
(2003)
J. Clin. Invest
, vol.111
, Issue.9
, pp. 1287-1295
-
-
Bergers, G.1
Song, S.2
Meyer-Morse, N.3
Bergsland, E.4
Hanahan, D.5
-
42
-
-
34547662268
-
Overexpression of PDGF-BB decreases colorectal and pancreatic cancer growth by increasing tumor pericyte content
-
Mccarty MF, Somcio RJ, Stoeltzing O et al. Overexpression of PDGF-BB decreases colorectal and pancreatic cancer growth by increasing tumor pericyte content. J. Clin. Invest. 117(8), 2114-2122 (2007
-
(2007)
J. Clin. Invest
, vol.117
, Issue.8
, pp. 2114-2122
-
-
McCarty, M.F.1
Somcio, R.J.2
Stoeltzing, O.3
-
43
-
-
77953802129
-
The absence of pericytes does not increase the sensitivity of tumor vasculature to vascular endothelial growth factor-A blockade
-
Nisancioglu MH, Betsholtz C, Genove G. The absence of pericytes does not increase the sensitivity of tumor vasculature to vascular endothelial growth factor-A blockade. Cancer Res. 70(12), 5109-5115 (2010
-
(2010)
Cancer Res
, vol.70
, Issue.12
, pp. 5109-5115
-
-
Nisancioglu, M.H.1
Betsholtz, C.2
Genove, G.3
-
44
-
-
84880287596
-
Tumour PDGF-BB expression levels determine dual effects of anti-PDGF drugs on vascular remodelling and metastasis
-
Hosaka K, Yang Y, Seki T et al. Tumour PDGF-BB expression levels determine dual effects of anti-PDGF drugs on vascular remodelling and metastasis. Nat. Commun. 4, 2129 (2013
-
(2013)
Nat. Commun
, vol.4
, pp. 2129
-
-
Hosaka, K.1
Yang, Y.2
Seki, T.3
-
45
-
-
1042301958
-
Targeting the platelet-derived growth factor receptor in antivascular therapy for human ovarian carcinoma
-
Apte SM, Fan D, Killion JJ, Fidler IJ. Targeting the platelet-derived growth factor receptor in antivascular therapy for human ovarian carcinoma. Clin. Cancer Res. 10(3), 897-908 (2004
-
(2004)
Clin. Cancer Res
, vol.10
, Issue.3
, pp. 897-908
-
-
Apte, S.M.1
Fan, D.2
Killion, J.J.3
Fidler, I.J.4
-
46
-
-
0346333243
-
Inhibition of platelet-derived growth factor receptor phosphorylation by STI571 (Gleevec) reduces growth and metastasis of human pancreatic carcinoma in an orthotopic nude mouse model
-
Hwang RF, Yokoi K, Bucana CD et al. Inhibition of platelet-derived growth factor receptor phosphorylation by STI571 (Gleevec) reduces growth and metastasis of human pancreatic carcinoma in an orthotopic nude mouse model. Clin. Cancer Res. 9(17), 6534-6544 (2003
-
(2003)
Clin. Cancer Res
, vol.9
, Issue.17
, pp. 6534-6544
-
-
Hwang, R.F.1
Yokoi, K.2
Bucana, C.D.3
-
47
-
-
11344264600
-
Inhibition of platelet-derived growth factor receptor signaling restricts the growth of human breast cancer in the bone of nude mice
-
Lev DC, Kim SJ, Onn A et al. Inhibition of platelet-derived growth factor receptor signaling restricts the growth of human breast cancer in the bone of nude mice. Clin. Cancer Res. 11(1), 306-314 (2005
-
(2005)
Clin. Cancer Res
, vol.11
, Issue.1
, pp. 306-314
-
-
Lev, D.C.1
Kim, S.J.2
Onn, A.3
-
48
-
-
10744227995
-
Effects of blocking platelet-derived growth factor-receptor signaling in a mouse model of experimental prostate cancer bone metastases
-
Uehara H, Kim SJ, Karashima T et al. Effects of blocking platelet-derived growth factor-receptor signaling in a mouse model of experimental prostate cancer bone metastases. J. Natl Cancer Inst. 95(6), 458-470 (2003
-
(2003)
J. Natl Cancer Inst
, vol.95
, Issue.6
, pp. 458-470
-
-
Uehara, H.1
Kim, S.J.2
Karashima, T.3
-
49
-
-
5444266254
-
PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis
-
Cao R, Bjorndahl MA, Religa P et al. PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis. Cancer Cell 6(4), 333-345 (2004
-
(2004)
Cancer Cell
, vol.6
, Issue.4
, pp. 333-345
-
-
Cao, R.1
Bjorndahl, M.A.2
Religa, P.3
-
50
-
-
57649135172
-
A role for VEGF as a negative regulator of pericyte function and vessel maturation
-
Greenberg JI, Shields DJ, Barillas SG et al. A role for VEGF as a negative regulator of pericyte function and vessel maturation. Nature 456(7223), 809-813 (2008
-
(2008)
Nature
, vol.456
, Issue.7223
, pp. 809-813
-
-
Greenberg, J.I.1
Shields, D.J.2
Barillas, S.G.3
-
51
-
-
44149090296
-
Role of platelet-derived growth factors in physiology and medicine
-
Andrae J, Gallini R, Betsholtz C. Role of platelet-derived growth factors in physiology and medicine. Genes Dev. 22(10), 1276-1312 (2008
-
(2008)
Genes Dev
, vol.22
, Issue.10
, pp. 1276-1312
-
-
Andrae, J.1
Gallini, R.2
Betsholtz, C.3
-
52
-
-
77952568396
-
Hallmarks of cancer: Interactions with the tumor stroma
-
Pietras K, Ostman A. Hallmarks of cancer: interactions with the tumor stroma. Exp Cell Res 316(8), 1324-1331 (2010
-
(2010)
Exp Cell Res
, vol.316
, Issue.8
, pp. 1324-1331
-
-
Pietras, K.1
Ostman, A.2
-
53
-
-
0032477806
-
Tumorigenic conversion of immortal human keratinocytes through stromal cell activation
-
Skobe M, Fusenig NE. Tumorigenic conversion of immortal human keratinocytes through stromal cell activation. Proc. Natl Acad. Sci. USA 95(3), 1050-1055 (1998
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, Issue.3
, pp. 1050-1055
-
-
Skobe, M.1
Fusenig, N.E.2
-
54
-
-
58249095931
-
Paracrine signaling by platelet-derived growth factor-CC promotes tumor growth by recruitment of cancer-associated fibroblasts
-
Anderberg C, Li H, Fredriksson L et al. Paracrine signaling by platelet-derived growth factor-CC promotes tumor growth by recruitment of cancer-associated fibroblasts. Cancer Res. 69(1), 369-378 (2009
-
(2009)
Cancer Res
, vol.69
, Issue.1
, pp. 369-378
-
-
Anderberg, C.1
Li, H.2
Fredriksson, L.3
-
55
-
-
0027397240
-
Platelet-derived growth factor (PDGF) in oncogenesis: Development of a vascular connective tissue stroma in xenotransplanted human melanoma producing PDGF-BB
-
Forsberg K, Valyi-Nagy I, Heldin CH, Herlyn M, Westermark B. Platelet-derived growth factor (PDGF) in oncogenesis: development of a vascular connective tissue stroma in xenotransplanted human melanoma producing PDGF-BB. Proc. Natl Acad. Sci. USA 90(2), 393-397 (1993
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, Issue.2
, pp. 393-397
-
-
Forsberg, K.1
Valyi-Nagy, I.2
Heldin, C.H.3
Herlyn, M.4
Westermark, B.5
-
56
-
-
38849202330
-
Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting
-
Pietras K, Pahler J, Bergers G, Hanahan D. Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting. PLoS Med. 5(1), e19 (2008
-
(2008)
PLoS Med
, vol.5
, Issue.1
-
-
Pietras, K.1
Pahler, J.2
Bergers, G.3
Hanahan, D.4
-
57
-
-
34547643983
-
Targeting the expression of platelet-derived growth factor receptor by reactive stroma inhibits growth and metastasis of human colon carcinoma
-
Kitadai Y, Sasaki T, Kuwai T, Nakamura T, Bucana CD, Fidler IJ. Targeting the expression of platelet-derived growth factor receptor by reactive stroma inhibits growth and metastasis of human colon carcinoma. Am. J. Pathol. 169(6), 2054-2065 (2006
-
(2006)
Am. J. Pathol
, vol.169
, Issue.6
, pp. 2054-2065
-
-
Kitadai, Y.1
Sasaki, T.2
Kuwai, T.3
Nakamura, T.4
Bucana, C.D.5
Fidler, I.J.6
-
58
-
-
0035291243
-
Delivery of molecular and cellular medicine to solid tumors
-
Jain RK. Delivery of molecular and cellular medicine to solid tumors. Adv. Drug Deliv. Rev. 46(1-3), 149-168 (2001
-
(2001)
Adv. Drug Deliv. Rev
, vol.46
, Issue.1-3
, pp. 149-168
-
-
Jain, R.K.1
-
59
-
-
4944266313
-
High interstitial fluid pressure-an obstacle in cancer therapy
-
Heldin CH, Rubin K, Pietras K, Ostman A. High interstitial fluid pressure-an obstacle in cancer therapy. Nat. Rev. Cancer 4(10), 806-813 (2004
-
(2004)
Nat. Rev. Cancer
, vol.4
, Issue.10
, pp. 806-813
-
-
Heldin, C.H.1
Rubin, K.2
Pietras, K.3
Ostman, A.4
-
60
-
-
24744462115
-
Effect of platelet-derived growth factor receptor-beta inhibition with STI571 on radioimmunotherapy
-
Baranowska-Kortylewicz J, Abe M, Pietras K et al. Effect of platelet-derived growth factor receptor-beta inhibition with STI571 on radioimmunotherapy. Cancer Res. 65(17), 7824-7831 (2005
-
(2005)
Cancer Res
, vol.65
, Issue.17
, pp. 7824-7831
-
-
Baranowska-Kortylewicz, J.1
Abe, M.2
Pietras, K.3
-
61
-
-
0035297541
-
Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors
-
Pietras K, Ostman A, Sjoquist M et al. Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors. Cancer Res. 61(7), 2929-2934 (2001
-
(2001)
Cancer Res
, vol.61
, Issue.7
, pp. 2929-2934
-
-
Pietras, K.1
Ostman, A.2
Sjoquist, M.3
-
62
-
-
0036790060
-
Inhibition of PDGF receptor signaling in tumor stroma enhances antitumor effect of chemotherapy
-
Pietras K, Rubin K, Sjoblom T et al. Inhibition of PDGF receptor signaling in tumor stroma enhances antitumor effect of chemotherapy. Cancer Res. 62(19), 5476-5484 (2002
-
(2002)
Cancer Res
, vol.62
, Issue.19
, pp. 5476-5484
-
-
Pietras, K.1
Rubin, K.2
Sjoblom, T.3
-
63
-
-
0141567995
-
STI571 enhances the therapeutic index of epothilone B by a tumor-selective increase of drug uptake
-
Pietras K, Stumm M, Hubert M et al. STI571 enhances the therapeutic index of epothilone B by a tumor-selective increase of drug uptake. Clin. Cancer Res. 9(10 Pt 1), 3779-3787 (2003
-
(2003)
Clin. Cancer Res
, vol.9
, Issue.10 PART 1
, pp. 3779-3787
-
-
Pietras, K.1
Stumm, M.2
Hubert, M.3
-
64
-
-
33745107179
-
A crucial function of PDGF in TGF-beta-mediated cancer progression of hepatocytes
-
Gotzmann J, Fischer AN, Zojer M et al. A crucial function of PDGF in TGF-beta-mediated cancer progression of hepatocytes. Oncogene 25(22), 3170-3185 (2006
-
(2006)
Oncogene
, vol.25
, Issue.22
, pp. 3170-3185
-
-
Gotzmann, J.1
Fischer, A.N.2
Zojer, M.3
-
65
-
-
33745192635
-
Autocrine PDGFR signaling promotes mammary cancer metastasis
-
Jechlinger M, Sommer A, Moriggl R et al. Autocrine PDGFR signaling promotes mammary cancer metastasis. J. Clin. Invest. 116(6), 1561-1570 (2006
-
(2006)
J. Clin. Invest
, vol.116
, Issue.6
, pp. 1561-1570
-
-
Jechlinger, M.1
Sommer, A.2
Moriggl, R.3
-
66
-
-
84878983107
-
Sox4 is a master regulator of epithelial-mesenchymal transition by controlling Ezh2 expression and epigenetic reprogramming
-
Tiwari N, Tiwari VK, Waldmeier L et al. Sox4 is a master regulator of epithelial-mesenchymal transition by controlling Ezh2 expression and epigenetic reprogramming. Cancer Cell 23(6), 768-783 (2013
-
(2013)
Cancer Cell
, vol.23
, Issue.6
, pp. 768-783
-
-
Tiwari, N.1
Tiwari, V.K.2
Waldmeier, L.3
-
67
-
-
84864287278
-
Cediranib inhibits both the intraosseous growth of PDGF D-positive prostate cancer cells and the associated bone reaction
-
Najy AJ, Jung YS, Won JJ et al. Cediranib inhibits both the intraosseous growth of PDGF D-positive prostate cancer cells and the associated bone reaction. Prostate 72(12), 1328-1338 (2012
-
(2012)
Prostate
, vol.72
, Issue.12
, pp. 1328-1338
-
-
Najy, A.J.1
Jung, Y.S.2
Won, J.J.3
-
68
-
-
33644643376
-
Pericytes limit tumor cell metastasis
-
Xian X, Hakansson J, Stahlberg A et al. Pericytes limit tumor cell metastasis. J. Clin. Invest. 116(3), 642-651 (2006
-
(2006)
J. Clin. Invest
, vol.116
, Issue.3
, pp. 642-651
-
-
Xian, X.1
Hakansson, J.2
Stahlberg, A.3
-
69
-
-
84855912001
-
Pericyte depletion results in hypoxia-associated epithelial-to- mesenchymal transition and metastasis mediated by met signaling pathway
-
Cooke VG, Lebleu VS, Keskin D et al. Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway. Cancer Cell 21(1), 66-81 (2012
-
(2012)
Cancer Cell
, vol.21
, Issue.1
, pp. 66-81
-
-
Cooke, V.G.1
Lebleu, V.S.2
Keskin, D.3
-
70
-
-
84874336387
-
STC1 expression by cancer-associated fibroblasts drives metastasis of colorectal cancer
-
Pena C, Cespedes MV, Lindh MB et al. STC1 expression by cancer-associated fibroblasts drives metastasis of colorectal cancer. Cancer Res. 73(4), 1287-1297 (2013
-
(2013)
Cancer Res
, vol.73
, Issue.4
, pp. 1287-1297
-
-
Pena, C.1
Cespedes, M.V.2
Lindh, M.B.3
-
71
-
-
84871365780
-
Stroma-directed imatinib therapy impairs the tumor-promoting effect of bone marrow-derived mesenchymal stem cells in an orthotopic transplantation model of colon cancer
-
Shinagawa K, Kitadai Y, Tanaka M et al. Stroma-directed imatinib therapy impairs the tumor-promoting effect of bone marrow-derived mesenchymal stem cells in an orthotopic transplantation model of colon cancer. Int. J. Cancer 132(4), 813-823 (2013
-
(2013)
Int. J. Cancer
, vol.132
, Issue.4
, pp. 813-823
-
-
Shinagawa, K.1
Kitadai, Y.2
Tanaka, M.3
-
72
-
-
34848917292
-
In situ detection of phosphorylated platelet-derived growth factor receptor beta using a generalized proximity ligation method
-
Jarvius M, Paulsson J, Weibrecht I et al. In situ detection of phosphorylated platelet-derived growth factor receptor beta using a generalized proximity ligation method. Mol. Cell Proteomics 6(9), 1500-1509 (2007
-
(2007)
Mol. Cell Proteomics
, vol.6
, Issue.9
, pp. 1500-1509
-
-
Jarvius, M.1
Paulsson, J.2
Weibrecht, I.3
-
73
-
-
84878238535
-
Prognostic significance in breast cancer of a gene signature capturing stromal PDGF signaling
-
Frings O, Augsten M, Tobin NP et al. Prognostic significance in breast cancer of a gene signature capturing stromal PDGF signaling. Am. J. Pathol. 182(6), 2037-2047 (2013
-
(2013)
Am. J. Pathol
, vol.182
, Issue.6
, pp. 2037-2047
-
-
Frings, O.1
Augsten, M.2
Tobin, N.P.3
-
74
-
-
1842863097
-
EGF-R and PDGF-R, but not bcl-2, overexpression predict overall survival in patients with low-grade astrocytomas
-
Varela M, Ranuncolo SM, Morand A et al. EGF-R and PDGF-R, but not bcl-2, overexpression predict overall survival in patients with low-grade astrocytomas. J. Surg. Oncol. 86(1), 34-40 (2004
-
(2004)
J. Surg. Oncol
, vol.86
, Issue.1
, pp. 34-40
-
-
Varela, M.1
Ranuncolo, S.M.2
Morand, A.3
-
75
-
-
0036266235
-
Prognostic value of platelet derived growth factor alpha receptor expression in grade 2 astrocytomas and oligoastrocytomas
-
Ribom D, Andrae J, Frielingsdorf M, Hartman M, Nister M, Smits A. Prognostic value of platelet derived growth factor alpha receptor expression in grade 2 astrocytomas and oligoastrocytomas. J. Neurol. Neurosurg. Psychiatry 72(6), 782-787 (2002
-
(2002)
J. Neurol. Neurosurg. Psychiatry
, vol.72
, Issue.6
, pp. 782-787
-
-
Ribom, D.1
Andrae, J.2
Frielingsdorf, M.3
Hartman, M.4
Nister, M.5
Smits, A.6
-
76
-
-
70249091030
-
Expression, mutation and copy number analysis of platelet-derived growth factor receptor A (PDGFRA) and its ligand PDGFA in gliomas
-
Martinho O, Longatto-Filho A, Lambros MB et al. Expression, mutation and copy number analysis of platelet-derived growth factor receptor A (PDGFRA) and its ligand PDGFA in gliomas. Br. J. Cancer 101(6), 973-982 (2009
-
(2009)
Br. J. Cancer
, vol.101
, Issue.6
, pp. 973-982
-
-
Martinho, O.1
Longatto-Filho, A.2
Lambros, M.B.3
-
77
-
-
79951966257
-
Prognostic but not predictive role of platelet-derived growth factor receptors in patients with recurrent glioblastoma
-
Paulsson J, Lindh MB, Jarvius M et al. Prognostic but not predictive role of platelet-derived growth factor receptors in patients with recurrent glioblastoma. Int. J. Cancer 128(8), 1981-1988 (2011
-
(2011)
Int. J. Cancer
, vol.128
, Issue.8
, pp. 1981-1988
-
-
Paulsson, J.1
Lindh, M.B.2
Jarvius, M.3
-
78
-
-
84879301451
-
Role of platelet derived growth factor receptor (PDGFR) over-expression and angiogenesis in ependymoma
-
Moreno L, Popov S, Jury A, Al Sarraj S, Jones C, Zacharoulis S. Role of platelet derived growth factor receptor (PDGFR) over-expression and angiogenesis in ependymoma. J. Neurooncol. 111(2), 169-176 (2013
-
(2013)
J. Neurooncol
, vol.111
, Issue.2
, pp. 169-176
-
-
Moreno, L.1
Popov, S.2
Jury, A.3
Al Sarraj, S.4
Jones, C.5
Zacharoulis, S.6
-
79
-
-
37549052922
-
Expression of KIT and PDGFR is associated with a good prognosis in neuroblastoma
-
Shimada A, Hirato J, Kuroiwa M et al. Expression of KIT and PDGFR is associated with a good prognosis in neuroblastoma. Pediatr. Blood Cancer 50(2), 213-217 (2008
-
(2008)
Pediatr. Blood Cancer
, vol.50
, Issue.2
, pp. 213-217
-
-
Shimada, A.1
Hirato, J.2
Kuroiwa, M.3
-
80
-
-
77950427275
-
Expression and prognostic value of platelet-derived growth factor-AA and its receptor alpha in nephroblastoma
-
Ghanem M, Nijman R, Safan M, Van Der Kwast T, Vansteenbrugge G. Expression and prognostic value of platelet-derived growth factor-AA and its receptor alpha in nephroblastoma. BJU Int. 106(9), 1389-1393 (2010
-
(2010)
BJU Int
, vol.106
, Issue.9
, pp. 1389-1393
-
-
Ghanem, M.1
Nijman, R.2
Safan, M.3
Van Der Kwast, T.4
Vansteenbrugge, G.5
-
81
-
-
77956281456
-
Stromal PDGFRbeta expression in prostate tumors and non-malignant prostate tissue predicts prostate cancer survival
-
Hagglof C, Hammarsten P, Josefsson A et al. Stromal PDGFRbeta expression in prostate tumors and non-malignant prostate tissue predicts prostate cancer survival. PLoS ONE 5(5), e10747 (2010
-
(2010)
PLoS ONE
, vol.5
, Issue.5
-
-
Hagglof, C.1
Hammarsten, P.2
Josefsson, A.3
-
82
-
-
0026341829
-
Platelet-derived growth factor (PDGF) in plasma of breast cancer patients: Correlation with stage and rate of progression
-
Ariad S, Seymour L, Bezwoda WR. Platelet-derived growth factor (PDGF) in plasma of breast cancer patients: correlation with stage and rate of progression. Breast Cancer Res. Treat 20(1), 11-17 (1991
-
(1991)
Breast Cancer Res. Treat
, vol.20
, Issue.1
, pp. 11-17
-
-
Ariad, S.1
Seymour, L.2
Bezwoda, W.R.3
-
83
-
-
0027997909
-
Positive immunostaining for platelet derived growth factor (PDGF) is an adverse prognostic factor in patients with advanced breast cancer
-
Seymour L, Bezwoda WR. Positive immunostaining for platelet derived growth factor (PDGF) is an adverse prognostic factor in patients with advanced breast cancer. Breast Cancer Res. Treat 32(2), 229-233 (1994
-
(1994)
Breast Cancer Res. Treat
, vol.32
, Issue.2
, pp. 229-233
-
-
Seymour, L.1
Bezwoda, W.R.2
-
84
-
-
33644873490
-
Overexpression of platelet-derived growth factor receptor alpha in breast cancer is associated with tumour progression
-
Carvalho I, Milanezi F, Martins A, Reis RM, Schmitt F. Overexpression of platelet-derived growth factor receptor alpha in breast cancer is associated with tumour progression. Breast Cancer Res. 7(5), R788-795 (2005
-
(2005)
Breast Cancer Res
, vol.7
, Issue.5
-
-
Carvalho, I.1
Milanezi, F.2
Martins, A.3
Reis, R.M.4
Schmitt, F.5
-
85
-
-
67649975270
-
Prognostic significance of stromal platelet-derived growth factor beta-receptor expression in human breast cancer
-
Paulsson J, Sjoblom T, Micke P et al. Prognostic significance of stromal platelet-derived growth factor beta-receptor expression in human breast cancer. Am. J. Pathol. 175(1), 334-341 (2009
-
(2009)
Am. J. Pathol
, vol.175
, Issue.1
, pp. 334-341
-
-
Paulsson, J.1
Sjoblom, T.2
Micke, P.3
-
86
-
-
58149106094
-
Prognostic impact of platelet-derived growth factors in non-small cell lung cancer tumor and stromal cells
-
Donnem T, Al-Saad S, Al-Shibli K, Andersen S, Busund LT, Bremnes RM. Prognostic impact of platelet-derived growth factors in non-small cell lung cancer tumor and stromal cells. J. Thorac. Oncol. 3(9), 963-970 (2008
-
(2008)
J. Thorac. Oncol
, vol.3
, Issue.9
, pp. 963-970
-
-
Donnem, T.1
Al-Saad, S.2
Al-Shibli, K.3
Andersen, S.4
Busund, L.T.5
Bremnes, R.M.6
-
87
-
-
77950402591
-
Co-expression of PDGF-B and VEGFR-3 strongly correlates with lymph node metastasis and poor survival in non-small-cell lung cancer
-
Donnem T, Al-Saad S, Al-Shibli K, Busund LT, Bremnes RM. Co-expression of PDGF-B and VEGFR-3 strongly correlates with lymph node metastasis and poor survival in non-small-cell lung cancer. Ann. Oncol. 21(2), 223-231 (2010
-
(2010)
Ann. Oncol
, vol.21
, Issue.2
, pp. 223-231
-
-
Donnem, T.1
Al-Saad, S.2
Al-Shibli, K.3
Busund, L.T.4
Bremnes, R.M.5
-
88
-
-
79959348456
-
Prognostic impact of angiogenic markers in non-small-cell lung cancer is related to tumor size
-
Donnem T, Andersen S, Al-Saad S, Al-Shibli K, Busund LT, Bremnes RM. Prognostic impact of angiogenic markers in non-small-cell lung cancer is related to tumor size. Clin. Lung Cancer 12(2), 106-115 (2011
-
(2011)
Clin. Lung Cancer
, vol.12
, Issue.2
, pp. 106-115
-
-
Donnem, T.1
Andersen, S.2
Al-Saad, S.3
Al-Shibli, K.4
Busund, L.T.5
Bremnes, R.M.6
-
89
-
-
79959836604
-
Expression and prognostic value of circulating angiogenic cytokines in pancreatic cancer
-
Rahbari NN, Schmidt T, Falk CS et al. Expression and prognostic value of circulating angiogenic cytokines in pancreatic cancer. BMC Cancer 11, 286 (2011
-
(2011)
BMC Cancer
, vol.11
, pp. 286
-
-
Rahbari, N.N.1
Schmidt, T.2
Falk, C.S.3
-
90
-
-
84867979311
-
PDGFRbeta expression in tumor stroma of pancreatic adenocarcinoma as a reliable prognostic marker
-
Yuzawa S, Kano MR, Einama T, Nishihara H. PDGFRbeta expression in tumor stroma of pancreatic adenocarcinoma as a reliable prognostic marker. Med. Oncol. 29(4), 2824-2830 (2012
-
(2012)
Med. Oncol
, vol.29
, Issue.4
, pp. 2824-2830
-
-
Yuzawa, S.1
Kano, M.R.2
Einama, T.3
Nishihara, H.4
-
91
-
-
84859699041
-
High KIT and PDGFRA are associated with shorter patients survival in gastroenteropancreatic neuroendocrine tumors, but mutations are a rare event
-
Knosel T, Chen Y, Altendorf-Hofmann A et al. High KIT and PDGFRA are associated with shorter patients survival in gastroenteropancreatic neuroendocrine tumors, but mutations are a rare event. J. Cancer Res. Clin. Oncol. 138(3), 397-403 (2012
-
(2012)
J. Cancer Res. Clin. Oncol
, vol.138
, Issue.3
, pp. 397-403
-
-
Knosel, T.1
Chen, Y.2
Altendorf-Hofmann, A.3
-
92
-
-
77955950139
-
Expression of platelet-derived growth factor (PDGF)-B and PDGF-receptor beta is associated with lymphatic metastasis in human gastric carcinoma
-
Kodama M, Kitadai Y, Sumida T et al. Expression of platelet-derived growth factor (PDGF)-B and PDGF-receptor beta is associated with lymphatic metastasis in human gastric carcinoma. Cancer Sci. 101(9), 1984-1989 (2010
-
(2010)
Cancer Sci
, vol.101
, Issue.9
, pp. 1984-1989
-
-
Kodama, M.1
Kitadai, Y.2
Sumida, T.3
-
93
-
-
84877759241
-
Clinicopathological significance of platelet-derived growth factor B, platelet-derived growth factor receptor-beta, and E-cadherin expression in gastric carcinoma
-
Guo Y, Yin J, Zha L, Wang Z. Clinicopathological significance of platelet-derived growth factor B, platelet-derived growth factor receptor-beta, and E-cadherin expression in gastric carcinoma. Contemp Oncol (Pozn) 17(2), 150-155 (2013
-
(2013)
Contemp Oncol (Pozn
, vol.17
, Issue.2
, pp. 150-155
-
-
Guo, Y.1
Yin, J.2
Zha, L.3
Wang, Z.4
-
94
-
-
78649460917
-
Clinicopathological significance of platelet-derived growth factor (PDGF)-B and vascular endothelial growth factor-A expression PDGF receptor-beta phosphorylation, and microvessel density in gastric cancer
-
Suzuki S, Dobashi Y, Hatakeyama Y et al. Clinicopathological significance of platelet-derived growth factor (PDGF)-B and vascular endothelial growth factor-A expression, PDGF receptor-beta phosphorylation, and microvessel density in gastric cancer. BMC Cancer 10, 659 (2010
-
(2010)
BMC Cancer
, vol.10
, pp. 659
-
-
Suzuki, S.1
Dobashi, Y.2
Hatakeyama, Y.3
-
95
-
-
0031887846
-
Prognostic value of platelet-derived growth factor-A (PDGF-A) in gastric carcinoma
-
Katano M, Nakamura M, Fujimoto K, Miyazaki K, Morisaki T. Prognostic value of platelet-derived growth factor-A (PDGF-A) in gastric carcinoma. Ann. Surg. 227(3), 365-371 (1998
-
(1998)
Ann. Surg
, vol.227
, Issue.3
, pp. 365-371
-
-
Katano, M.1
Nakamura, M.2
Fujimoto, K.3
Miyazaki, K.4
Morisaki, T.5
-
96
-
-
34547766599
-
Prognostic significance of platelet-derived growth factor-BB expression in human esophageal squamous cell carcinomas
-
Matsumoto S, Yamada Y, Narikiyo M et al. Prognostic significance of platelet-derived growth factor-BB expression in human esophageal squamous cell carcinomas. Anticancer Res. 27(4B), 2409-2414 (2007
-
(2007)
Anticancer Res
, vol.27
, Issue.4 B
, pp. 2409-2414
-
-
Matsumoto, S.1
Yamada, Y.2
Narikiyo, M.3
-
97
-
-
48149096720
-
PDGF-BB is a novel prognostic factor in colorectal cancer
-
Nakamura Y, Tanaka F, Yoshikawa Y et al. PDGF-BB is a novel prognostic factor in colorectal cancer. Ann. Surg. Oncol. 15(8), 2129-2136 (2008
-
(2008)
Ann. Surg. Oncol
, vol.15
, Issue.8
, pp. 2129-2136
-
-
Nakamura, Y.1
Tanaka, F.2
Yoshikawa, Y.3
-
98
-
-
84868116667
-
Platelet-derived growth factor may be a potential diagnostic and prognostic marker for cholangiocarcinoma
-
Boonjaraspinyo S, Boonmars T, Wu Z et al. Platelet-derived growth factor may be a potential diagnostic and prognostic marker for cholangiocarcinoma. Tumour Biol. 33(5), 1785-1802 (2012
-
(2012)
Tumour Biol
, vol.33
, Issue.5
, pp. 1785-1802
-
-
Boonjaraspinyo, S.1
Boonmars, T.2
Wu, Z.3
-
99
-
-
12344312294
-
Genetic alterations and protein expression of KIT and PDGFRA in serous ovarian carcinoma
-
Lassus H, Sihto H, Leminen A et al. Genetic alterations and protein expression of KIT and PDGFRA in serous ovarian carcinoma. Br. J. Cancer 91(12), 2048-2055 (2004
-
(2004)
Br. J. Cancer
, vol.91
, Issue.12
, pp. 2048-2055
-
-
Lassus, H.1
Sihto, H.2
Leminen, A.3
-
100
-
-
0031785456
-
The effects of platelet-derived growth factor and receptor on normal and neoplastic human ovarian surface epithelium
-
Dabrow MB, Francesco MR, Mcbrearty FX, Caradonna S. The effects of platelet-derived growth factor and receptor on normal and neoplastic human ovarian surface epithelium. Gynecol. Oncol. 71(1), 29-37 (1998
-
(1998)
Gynecol. Oncol
, vol.71
, Issue.1
, pp. 29-37
-
-
Dabrow, M.B.1
Francesco, M.R.2
McBrearty, F.X.3
Caradonna, S.4
-
101
-
-
85047688292
-
Expression of platelet-derived growth factor-alpha alpha receptor is associated with tumor progression in clear cell renal cell carcinoma
-
Sulzbacher I, Birner P, Traxler M, Marberger M, Haitel A. Expression of platelet-derived growth factor-alpha alpha receptor is associated with tumor progression in clear cell renal cell carcinoma. Am. J. Clin. Pathol. 120(1), 107-112 (2003
-
(2003)
Am. J. Clin. Pathol
, vol.120
, Issue.1
, pp. 107-112
-
-
Sulzbacher, I.1
Birner, P.2
Traxler, M.3
Marberger, M.4
Haitel, A.5
-
102
-
-
84873986377
-
Prognostic prediction in patients with metastatic renal cell carcinoma treated with sorafenib based on expression levels of potential molecular markers in radical nephrectomy specimens
-
Kusuda Y, Miyake H, Behnsawy HM, Fukuhara T, Inoue TA, Fujisawa M. Prognostic prediction in patients with metastatic renal cell carcinoma treated with sorafenib based on expression levels of potential molecular markers in radical nephrectomy specimens. Urol. Oncol. 31(1), 42-50 (2013
-
(2013)
Urol. Oncol
, vol.31
, Issue.1
, pp. 42-50
-
-
Kusuda, Y.1
Miyake, H.2
Behnsawy, H.M.3
Fukuhara, T.4
Inoue, T.A.5
Fujisawa, M.6
-
103
-
-
84875657918
-
Expression and prognostic value of VEGFR-2 PDGFR-beta, and c-Met in advanced hepatocellular carcinoma
-
Chu JS, Ge FJ, Zhang B et al. Expression and prognostic value of VEGFR-2, PDGFR-beta, and c-Met in advanced hepatocellular carcinoma. J. Exp. Clin. Cancer Res. 32, 16 (2013
-
(2013)
J. Exp. Clin. Cancer Res
, vol.32
, pp. 16
-
-
Chu, J.S.1
Ge, F.J.2
Zhang, B.3
-
104
-
-
39749105871
-
Platelet-derived growth factor receptor expression and amplification in choroid plexus carcinomas
-
Nupponen NN, Paulsson J, Jeibmann A et al. Platelet-derived growth factor receptor expression and amplification in choroid plexus carcinomas. Mod. Pathol. 21(3), 265-270 (2008
-
(2008)
Mod. Pathol
, vol.21
, Issue.3
, pp. 265-270
-
-
Nupponen, N.N.1
Paulsson, J.2
Jeibmann, A.3
-
105
-
-
73549091707
-
Platelet-derived growth factor receptor expression and activation in choroid plexus tumors
-
Koos B, Paulsson J, Jarvius M et al. Platelet-derived growth factor receptor expression and activation in choroid plexus tumors. Am. J. Pathol. 175(4), 1631-1637 (2009
-
(2009)
Am. J. Pathol
, vol.175
, Issue.4
, pp. 1631-1637
-
-
Koos, B.1
Paulsson, J.2
Jarvius, M.3
-
106
-
-
32044469857
-
Rhabdomyosarcomas utilize developmental, myogenic growth factors for disease advantage: A report from the Children's Oncology Group
-
Blandford MC, Barr FG, Lynch JC, Randall RL, Qualman SJ, Keller C. Rhabdomyosarcomas utilize developmental, myogenic growth factors for disease advantage: a report from the Children's Oncology Group. Pediatr. Blood Cancer 46(3), 329-338 (2006
-
(2006)
Pediatr. Blood Cancer
, vol.46
, Issue.3
, pp. 329-338
-
-
Blandford, M.C.1
Barr, F.G.2
Lynch, J.C.3
Randall, R.L.4
Qualman, S.J.5
Keller, C.6
-
107
-
-
40849114332
-
Microarray analysis of Ewing's sarcoma family of tumours reveals characteristic gene expression signatures associated with metastasis and resistance to chemotherapy
-
Schaefer KL, Eisenacher M, Braun Y et al. Microarray analysis of Ewing's sarcoma family of tumours reveals characteristic gene expression signatures associated with metastasis and resistance to chemotherapy. Eur. J. Cancer 44(5), 699-709 (2008
-
(2008)
Eur. J. Cancer
, vol.44
, Issue.5
, pp. 699-709
-
-
Schaefer, K.L.1
Eisenacher, M.2
Braun, Y.3
-
108
-
-
84876010686
-
Distinct effects of ligand-induced PDGFRalpha and PDGFRbeta signaling in the human rhabdomyosarcoma tumor cell and stroma cell compartments
-
Ehnman M, Missiaglia E, Folestad E et al. Distinct effects of ligand-induced PDGFRalpha and PDGFRbeta signaling in the human rhabdomyosarcoma tumor cell and stroma cell compartments. Cancer Res. 73(7), 2139-2149 (2013
-
(2013)
Cancer Res
, vol.73
, Issue.7
, pp. 2139-2149
-
-
Ehnman, M.1
Missiaglia, E.2
Folestad, E.3
-
109
-
-
84884680394
-
Analyses of potential predictive markers and survival data for a response to sunitinib in patients with metastatic renal cell carcinoma
-
Dornbusch J, Zacharis A, Meinhardt M et al. Analyses of potential predictive markers and survival data for a response to sunitinib in patients with metastatic renal cell carcinoma. PLoS ONE 8(9), e76386 (2013
-
(2013)
PLoS ONE
, vol.8
, Issue.9
-
-
Dornbusch, J.1
Zacharis, A.2
Meinhardt, M.3
-
110
-
-
84906557976
-
Tumor perivascular PDGFBR as an independent prognostic factor in metastatic colorectal cancer
-
Chigago, IL, USA, 31 May-4 June
-
Bradic Lindh M, Mezheyeuski A, Glimelius B et al. Tumor perivascular PDGFBR as an independent prognostic factor in metastatic colorectal cancer. Presented at: 2013 ASCO Annual Meeting, Chigago, IL, USA, 31 May-4 June 2013
-
(2013)
Presented At: 2013 ASCO Annual Meeting
-
-
Bradic Lindh, M.1
Mezheyeuski, A.2
Glimelius, B.3
-
111
-
-
84868640245
-
The tumor microenvironment controls drug sensitivity
-
Ostman A. The tumor microenvironment controls drug sensitivity. Nat. Med. 18(9), 1332-1334 (2012
-
(2012)
Nat. Med
, vol.18
, Issue.9
, pp. 1332-1334
-
-
Ostman, A.1
-
112
-
-
14644446018
-
"chemo-switch" regimen is antiangiogenic, producing objective responses and survival benefit in a mouse model of cancer
-
Pietras K, Hanahan D. A multitargeted, metronomic, and maximum-tolerated dose "chemo-switch" regimen is antiangiogenic, producing objective responses and survival benefit in a mouse model of cancer. J. Clin. Oncol. 23(5), 939-952 (2005
-
(2005)
J. Clin. Oncol
, vol.23
, Issue.5
, pp. 939-952
-
-
Pietras, K.1
Hanahan, D.2
-
113
-
-
84864085607
-
Clinically used breast cancer markers such as estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 are unstable throughout tumor progression
-
Lindstrom LS, Karlsson E, Wilking UM et al. Clinically used breast cancer markers such as estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 are unstable throughout tumor progression. J. Clin. Oncol. 30(21), 2601-2608 (2012
-
(2012)
J. Clin. Oncol
, vol.30
, Issue.21
, pp. 2601-2608
-
-
Lindstrom, L.S.1
Karlsson, E.2
Wilking, U.M.3
-
114
-
-
79952313111
-
Engineered high-affinity affibody molecules targeting platelet-derived growth factor receptor beta in vivo
-
Lindborg M, Cortez E, Hoiden-Guthenberg I et al. Engineered high-affinity affibody molecules targeting platelet-derived growth factor receptor beta in vivo. J. Mol. Biol. 407(2), 298-315 (2011
-
(2011)
J. Mol. Biol.
, vol.407
, Issue.2
, pp. 298-315
-
-
Lindborg, M.1
Cortez, E.2
Hoiden-Guthenberg, I.3
-
115
-
-
77951768789
-
Design of an optimized scaffold for affibody molecules
-
Feldwisch J, Tolmachev V, Lendel C et al. Design of an optimized scaffold for affibody molecules. J. Mol. Biol. 398(2), 232-247 (2010).
-
(2010)
J. Mol. Biol
, vol.398
, Issue.2
, pp. 232-247
-
-
Feldwisch, J.1
Tolmachev, V.2
Lendel, C.3
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