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Volumn 29, Issue 4, 2012, Pages 2824-2830

PDGFRβ expression in tumor stroma of pancreatic adenocarcinoma as a reliable prognostic marker

Author keywords

Pancreatic adenocarcinoma; PDGFR ; Prognosis; SMA; Tumor stroma

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CD31 ANTIGEN; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; TUMOR MARKER;

EID: 84867979311     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-012-0193-0     Document Type: Article
Times cited : (58)

References (30)
  • 1
    • 8244254377 scopus 로고    scopus 로고
    • Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial
    • 9196156 1:CAS:528:DyaK2sXlsFKksLY%3D
    • Burris HA, Moore MJ, Andersen J, et al. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol. 1997;15:2403-13.
    • (1997) J Clin Oncol , vol.15 , pp. 2403-2413
    • Burris, H.A.1    Moore, M.J.2    Andersen, J.3
  • 2
    • 42049114228 scopus 로고    scopus 로고
    • Tumor-node-metastasis staging of pancreatic adenocarcinoma
    • 18272835 10.3322/CA.2007.0012
    • Katz MHG, Hwang R, Fleming JB, et al. Tumor-node-metastasis staging of pancreatic adenocarcinoma. CA Cancer J Clin. 2008;58:111-25.
    • (2008) CA Cancer J Clin , vol.58 , pp. 111-125
    • Katz, M.H.G.1    Hwang, R.2    Fleming, J.B.3
  • 3
    • 79955472083 scopus 로고    scopus 로고
    • Meta-analysis of immunohistochemical prognostic markers in resected pancreatic cancer
    • 21448172 10.1038/bjc.2011.110 1:CAS:528:DC%2BC3MXlt1GktLs%3D
    • Smith RA, Tang J, Tudur-Smith C, et al. Meta-analysis of immunohistochemical prognostic markers in resected pancreatic cancer. Br J Cancer. 2011;104:1440-51.
    • (2011) Br J Cancer , vol.104 , pp. 1440-1451
    • Smith, R.A.1    Tang, J.2    Tudur-Smith, C.3
  • 4
    • 79959837073 scopus 로고    scopus 로고
    • Major molecular markers in pancreatic ductal adenocarcinoma and their roles in screening, diagnosis, prognosis, and treatment
    • 21673535 10.1097/MPA.0b013e31821ff741
    • Singh P, Srinivasan R, Wig JD. Major molecular markers in pancreatic ductal adenocarcinoma and their roles in screening, diagnosis, prognosis, and treatment. Pancreas. 2011;40:644-52.
    • (2011) Pancreas , vol.40 , pp. 644-652
    • Singh, P.1    Srinivasan, R.2    Wig, J.D.3
  • 5
    • 30344461873 scopus 로고    scopus 로고
    • Important prognostic histological parameters for patients with invasive ductal carcinoma of the pancreas
    • 16367904 10.1111/j.1349-7006.2005.00128.x 1:CAS:528: DC%2BD28XotFWitA%3D%3D
    • Mitsunaga S, Hasebe T, Iwasaki M, et al. Important prognostic histological parameters for patients with invasive ductal carcinoma of the pancreas. Cancer Sci. 2005;96:858-65.
    • (2005) Cancer Sci , vol.96 , pp. 858-865
    • Mitsunaga, S.1    Hasebe, T.2    Iwasaki, M.3
  • 6
    • 51049105755 scopus 로고    scopus 로고
    • The role of the tumor microenvironment in the progression of pancreatic cancer
    • 18639248 10.1016/j.jss.2007.12.757
    • Farrow B, Albo D, Berger DH. The role of the tumor microenvironment in the progression of pancreatic cancer. J Surg Res. 2008;149:319-28.
    • (2008) J Surg Res , vol.149 , pp. 319-328
    • Farrow, B.1    Albo, D.2    Berger, D.H.3
  • 7
    • 77957726424 scopus 로고    scopus 로고
    • Tumor microenvironment and progression of pancreatic cancer
    • 21403605 1:STN:280:DC%2BC3M3ms1yitg%3D%3D
    • Erkan M, Reiser-Erkan C, Michalski CW, et al. Tumor microenvironment and progression of pancreatic cancer. Exp Oncol. 2010;32:128-31.
    • (2010) Exp Oncol , vol.32 , pp. 128-131
    • Erkan, M.1    Reiser-Erkan, C.2    Michalski, C.W.3
  • 8
    • 33646384428 scopus 로고    scopus 로고
    • Fibroblasts in cancer
    • 16572188 10.1038/nrc1877 1:CAS:528:DC%2BD28XjslGitLw%3D
    • Kalluri R, Zeisberg M. Fibroblasts in cancer. Nat Rev Cancer. 2006;6:392-401.
    • (2006) Nat Rev Cancer , vol.6 , pp. 392-401
    • Kalluri, R.1    Zeisberg, M.2
  • 9
    • 77957913899 scopus 로고    scopus 로고
    • New insights into the mechanism of fibroblast to myofibroblast transformation and associated pathologies
    • 20630469 10.1016/S1937-6448(10)82004-0 1:CAS:528:DC%2BC3MXitlWjtw%3D%3D
    • Watsky MA, Weber KT, Sun Y, et al. New insights into the mechanism of fibroblast to myofibroblast transformation and associated pathologies. Int Rev Cell Mol Biol. 2010;282:165-92.
    • (2010) Int Rev Cell Mol Biol , vol.282 , pp. 165-192
    • Watsky, M.A.1    Weber, K.T.2    Sun, Y.3
  • 10
    • 0029869237 scopus 로고    scopus 로고
    • Platelet-derived growth factor-BB induces renal tubulointerstitial myofibroblast formation and tubulointerstitial fibrosis
    • 8644858 1:CAS:528:DyaK28XivFaiu7o%3D
    • Tang WW, Ulich TR, Lacey DL, et al. Platelet-derived growth factor-BB induces renal tubulointerstitial myofibroblast formation and tubulointerstitial fibrosis. Am J Pathol. 1996;148:1169-80.
    • (1996) Am J Pathol , vol.148 , pp. 1169-1180
    • Tang, W.W.1    Ulich, T.R.2    Lacey, D.L.3
  • 11
    • 64849109182 scopus 로고    scopus 로고
    • Corneal stroma PDGF blockade and myofibroblast development
    • 19133260 10.1016/j.exer.2008.12.006 1:CAS:528:DC%2BD1MXltVymsLs%3D
    • Kaur H, Chaurasia SS, de Medeiros FW, et al. Corneal stroma PDGF blockade and myofibroblast development. Exp Eye Res. 2009;88:960-5.
    • (2009) Exp Eye Res , vol.88 , pp. 960-965
    • Kaur, H.1    Chaurasia, S.S.2    De Medeiros, F.W.3
  • 12
    • 67649975270 scopus 로고    scopus 로고
    • Prognostic significance of stromal platelet-derived growth factor beta-receptor expression in human breast cancer
    • 19498003 10.2353/ajpath.2009.081030
    • Paulsson J, Sjöblom T, Micke P, et al. Prognostic significance of stromal platelet-derived growth factor beta-receptor expression in human breast cancer. Am J Pathol. 2009;175:334-41.
    • (2009) Am J Pathol , vol.175 , pp. 334-341
    • Paulsson, J.1    Sjöblom, T.2    Micke, P.3
  • 13
    • 2942682933 scopus 로고    scopus 로고
    • Insight into the physiological functions of PDGF through genetic studies in mice
    • 15207813 10.1016/j.cytogfr.2004.03.005 1:CAS:528:DC%2BD2cXltVKht7Y%3D
    • Betsholtz C. Insight into the physiological functions of PDGF through genetic studies in mice. Cytokine Growth Factor Rev. 2004;15:215-28.
    • (2004) Cytokine Growth Factor Rev , vol.15 , pp. 215-228
    • Betsholtz, C.1
  • 14
    • 34047127376 scopus 로고    scopus 로고
    • PDGF receptors as targets in tumor treatment
    • 17419949 10.1016/S0065-230X(06)97011-0
    • Ostman A, Heldin C-H. PDGF receptors as targets in tumor treatment. Adv Cancer Res. 2007;97:247-74.
    • (2007) Adv Cancer Res , vol.97 , pp. 247-274
    • Ostman, A.1    Heldin, C.-H.2
  • 15
    • 0037103624 scopus 로고    scopus 로고
    • Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta
    • 12181402 10.1056/NEJMoa020150 1:CAS:528:DC%2BD38XmtV2nt7g%3D
    • Apperley JF, Gardembas M, Melo JV, et al. Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta. N Engl J Med. 2002;347:481-7.
    • (2002) N Engl J Med , vol.347 , pp. 481-487
    • Apperley, J.F.1    Gardembas, M.2    Melo, J.V.3
  • 16
    • 0003638614 scopus 로고    scopus 로고
    • Japan Panceas Society 3 Kanehara Co. Tokyo
    • Japan Panceas Society. Classification of pancreatic carcinoma. 3rd ed. Tokyo: Kanehara Co.; 2011.
    • (2011) Classification of Pancreatic Carcinoma
  • 18
    • 33845998896 scopus 로고    scopus 로고
    • The pancreatic stellate cell: A star on the rise in pancreatic diseases
    • 17200706 10.1172/JCI30082 1:CAS:528:DC%2BD2sXmvV2rtg%3D%3D
    • Omary MB, Lugea A, Lowe AW, et al. The pancreatic stellate cell: a star on the rise in pancreatic diseases. J Clin Invest. 2007;117:50-9.
    • (2007) J Clin Invest , vol.117 , pp. 50-59
    • Omary, M.B.1    Lugea, A.2    Lowe, A.W.3
  • 19
    • 52149094275 scopus 로고    scopus 로고
    • The activated stroma index is a novel and independent prognostic marker in pancreatic ductal adenocarcinoma
    • 18639493 10.1016/j.cgh.2008.05.006
    • Erkan M, Michalski CW, Rieder S, et al. The activated stroma index is a novel and independent prognostic marker in pancreatic ductal adenocarcinoma. Clin Gastroenterol Hepatol. 2008;6:1155-61.
    • (2008) Clin Gastroenterol Hepatol , vol.6 , pp. 1155-1161
    • Erkan, M.1    Michalski, C.W.2    Rieder, S.3
  • 20
    • 0031842971 scopus 로고    scopus 로고
    • Periacinar stellate shaped cells in rat pancreas: Identification, isolation, and culture
    • 9771417 10.1136/gut.43.1.128 1:STN:280:DyaK1cvksVemtA%3D%3D
    • Apte MV, Haber PS, Applegate TL, et al. Periacinar stellate shaped cells in rat pancreas: identification, isolation, and culture. Gut. 1998;43:128-33.
    • (1998) Gut , vol.43 , pp. 128-133
    • Apte, M.V.1    Haber, P.S.2    Applegate, T.L.3
  • 21
    • 71849097007 scopus 로고    scopus 로고
    • Roles of pancreatic stellate cells in pancreatic inflammation and fibrosis
    • 19896099 10.1016/j.cgh.2009.07.038 1:CAS:528:DC%2BC3cXlsFOjtA%3D%3D
    • Masamune A, Watanabe T, Kikuta K, et al. Roles of pancreatic stellate cells in pancreatic inflammation and fibrosis. Clin Gastroenterol Hepatol. 2009;7:S48-54.
    • (2009) Clin Gastroenterol Hepatol , vol.7
    • Masamune, A.1    Watanabe, T.2    Kikuta, K.3
  • 22
    • 4644317795 scopus 로고    scopus 로고
    • Desmoplastic reaction in pancreatic cancer: Role of pancreatic stellate cells
    • 15367883 10.1097/00006676-200410000-00002 1:STN:280: DC%2BD2cvlvF2ntQ%3D%3D
    • Apte MV, Park S, Phillips PA, et al. Desmoplastic reaction in pancreatic cancer: role of pancreatic stellate cells. Pancreas. 2004;29:179-87.
    • (2004) Pancreas , vol.29 , pp. 179-187
    • Apte, M.V.1    Park, S.2    Phillips, P.A.3
  • 23
    • 17144404527 scopus 로고    scopus 로고
    • Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells
    • 15825074 10.1053/j.gastro.2004.12.036 1:CAS:528:DC%2BD2MXjvV2qt7w%3D
    • Bachem MG, Schünemann M, Ramadani M, et al. Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells. Gastroenterology. 2005;128:907-21.
    • (2005) Gastroenterology , vol.128 , pp. 907-921
    • Bachem, M.G.1    Schünemann, M.2    Ramadani, M.3
  • 24
    • 38849141696 scopus 로고    scopus 로고
    • Cancer-associated stromal fibroblasts promote pancreatic tumor progression
    • 18245495 10.1158/0008-5472.CAN-07-5714 1:CAS:528:DC%2BD1cXhtlygtbs%3D
    • Hwang RF, Moore T, Arumugam T, et al. Cancer-associated stromal fibroblasts promote pancreatic tumor progression. Cancer Res. 2008;68:918-26.
    • (2008) Cancer Res , vol.68 , pp. 918-926
    • Hwang, R.F.1    Moore, T.2    Arumugam, T.3
  • 25
    • 42049097658 scopus 로고    scopus 로고
    • Pancreatic stellate cells: Partners in crime with pancreatic cancer cells
    • 18381413 10.1158/0008-5472.CAN-07-2477 1:CAS:528:DC%2BD1cXktVyqtbs%3D
    • Vonlaufen A, Joshi S, Qu C, et al. Pancreatic stellate cells: partners in crime with pancreatic cancer cells. Cancer Res. 2008;68:2085-93.
    • (2008) Cancer Res , vol.68 , pp. 2085-2093
    • Vonlaufen, A.1    Joshi, S.2    Qu, C.3
  • 26
    • 77956281456 scopus 로고    scopus 로고
    • Stromal PDGFRbeta expression in prostate tumors and non-malignant prostate tissue predicts prostate cancer survival
    • 20505768 10.1371/journal.pone.0010747
    • Hägglöf C, Hammarsten P, Josefsson A, et al. Stromal PDGFRbeta expression in prostate tumors and non-malignant prostate tissue predicts prostate cancer survival. PLoS ONE. 2010;5:e10747.
    • (2010) PLoS ONE , vol.5 , pp. 10747
    • Hägglöf, C.1    Hammarsten, P.2    Josefsson, A.3
  • 27
    • 0027397240 scopus 로고
    • Platelet-derived growth factor (PDGF) in oncogenesis: Development of a vascular connective tissue stroma in xenotransplanted human melanoma producing PDGF-BB
    • 8380638 10.1073/pnas.90.2.393 1:CAS:528:DyaK3sXht1Wqu7w%3D
    • Forsberg K, Valyi-Nagy I, Heldin CH, et al. Platelet-derived growth factor (PDGF) in oncogenesis: development of a vascular connective tissue stroma in xenotransplanted human melanoma producing PDGF-BB. Proc Natl Acad Sci USA. 1993;90:393-7.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 393-397
    • Forsberg, K.1    Valyi-Nagy, I.2    Heldin, C.H.3
  • 28
    • 0034618408 scopus 로고    scopus 로고
    • Human breast carcinoma desmoplasia is PDGF initiated
    • 10980609 10.1038/sj.onc.1203785 1:CAS:528:DC%2BD3cXmvVyqs70%3D
    • Shao ZM, Nguyen M, Barsky SH. Human breast carcinoma desmoplasia is PDGF initiated. Oncogene. 2000;19:4337-45.
    • (2000) Oncogene , vol.19 , pp. 4337-4345
    • Shao, Z.M.1    Nguyen, M.2    Barsky, S.H.3
  • 29
    • 0034323610 scopus 로고    scopus 로고
    • Role of fibroblast activation in inducing interstitial fibrosis
    • 11132027
    • Zeisberg M, Strutz F, Müller GA. Role of fibroblast activation in inducing interstitial fibrosis. J Nephrol. 2000;13:S111-20.
    • (2000) J Nephrol , vol.13
    • Zeisberg, M.1    Strutz, F.2    Müller, G.A.3
  • 30
    • 0005945560 scopus 로고
    • Synthesis and secretion of platelet-derived growth factor by human breast cancer cell lines
    • 3039506 10.1073/pnas.84.16.5763 1:CAS:528:DyaL2sXlslems7g%3D
    • Bronzert DA, Pantazis P, Antoniades HN, et al. Synthesis and secretion of platelet-derived growth factor by human breast cancer cell lines. Proc Natl Acad Sci USA. 1987;84:5763-7.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 5763-5767
    • Bronzert, D.A.1    Pantazis, P.2    Antoniades, H.N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.