UVB radiation illuminates the role of TLR3 in the epidermis

Journal of Investigative Dermatology

Volumn 134, Issue 9, 2014, Pages 2315-2320

  Borkowski, Andrew W ^a   Gallo, Richard L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TLR3 PROTEIN, HUMAN; DOUBLE STRANDED RNA;

ANTIGEN RECOGNITION; CELL DAMAGE; CELL DEATH; COMMENSAL; DERMATITIS; EPIDERMIS; GENE EXPRESSION; HUMAN; INNATE IMMUNITY; KERATINOCYTE; PRIORITY JOURNAL; RADIATION EXPOSURE; RADIATION INDUCED NEOPLASM; RADIATION INJURY; REVIEW; SKIN CANCER; SKIN DEFECT; SKIN FLORA; SKIN TUMOR; SUNBURN; ULTRAVIOLET B RADIATION; DNA DAMAGE; GENETICS; PATHOLOGY; RADIATION RESPONSE; SKIN DISEASE; ULTRAVIOLET RADIATION; INFLAMMATION; PROTEIN FUNCTION;

DNA DAMAGE; EPIDERMIS; HUMANS; SKIN DISEASES; TOLL-LIKE RECEPTOR 3; ULTRAVIOLET RAYS;

EID: 84906313580     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2014.167     Document Type: Review

References (62)

1. Ahmad I, Simanyi E, Guroji P, et al. (2014). Toll-like receptor-4 deficiency enhances repair of UVR-induced cutaneous dna damage by nucleotide excision repair mechanism. J Invest Dermatol; advance online publication 2 January 2014 (doi:10.1038/jid.2013.530
2. Basu S, Binder RJ, Suto R, et al. (2000). Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathway. Int Immunol 12:1539-46
3. Berghe TV, Vanlangenakker N, Parthoens E, et al. (2010). Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features. Cell Death Differ 17:922-30
4. Bernard JJ, Cowing-Zitron C, Nakatsuji T, et al. (2012). Ultraviolet radiation damages self noncoding RNA and is detected by TLR3. Nat Med 18:1286-90
5. Black AT, Gray JP, Shakarjian MP, et al. (2008). UVB light upregulates prostaglandin synthases and prostaglandin receptors in mouse keratinocytes. Toxicol Appl Pharmacol 232:14-24
6. Borkowski AW, Park K, Uchida Y, et al. (2013). Activation of TLR3 in keratinocytes increases expression of genes involved in formation of the epidermis, lipid accumulation, and epidermal organelles. J Invest Dermatol 133:2031-40
7. Bours MJL, Swennen ELR, Di Virgilio F, et al. (2006). Adenosine 50-Triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation. Pharmacol Ther 112:358-404
8. Candi E, Schmidt R, Melino G. (2005). The cornified envelope: A model of cell death in the skin. Nat Rev Mol Cell Biol 6:328-40
9. Caricchio R, McPhie L, Cohen PL. (2003). Ultraviolet B radiation-induced cell death: Critical role of ultraviolet dose in inflammation and lupus autoantigen redistribution. J Immunol 171:5778-86
10. Cataisson C, Salcedo R, Hakim S, et al. (2012). IL-1R-MyD88 signaling in keratinocyte transformation and carcinogenesis. J Exp Med 209:1689-702
11. Cavassani KA, Ishii M, Wen H, et al. (2008). TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events. J Exp Med 205: 2609-21
12. Cho YS, Challa S, Moquin D, et al. (2009). Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 137:1112-23
13. Feldmeyer L, Keller M, Niklaus G, et al. (2007). The inflammasome mediates UVB-induced activation and secretion of interleukin-1beta by keratinocytes. Curr Biol 17:1140-5
14. Fernandes-Alnemri T, Wu J, Yu J-W, et al. (2007). The pyroptosome: A supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation. Cell Death Differ 14:1590-604
15. Freire-de-Lima CG, Xiao YQ, Gardai SJ, et al. (2006). Apoptotic cells, through transforming growth factor-beta, coordinately induce anti-inflammatory and suppress pro-inflammatory eicosanoid and NO synthesis in murine macrophages. J Biol Chem 281:38376-84
16. Galluzzi L, Vitale I, Abrams JM, et al. (2012). Molecular definitions of cell death subroutines: Recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death Differ 19:107-20
17. Gao M, Ha T, Zhang X, et al. (2012). Toll-like receptor 3 plays a central role in cardiac dysfunction during polymicrobial sepsis. Crit Care Med 40: 2390-9
18. Gruber JV, Holtz R. (2013). Examining communication between ultraviolet (UV)-damaged cutaneous nerve cells and epidermal keratinocytes in vitro. Toxicol Ind Health 25:225-30
19. Grundmann SA, Beissert S. (2012). Modern aspects of phototherapy for atopic dermatitis. J Allergy 2012:1-8
20. Harberts E, Fishelevich R, Liu J, et al. (2014). MyD88 mediates the decision to die by apoptosis or necroptosis after UV irradiation. Innate Immun; advance online publication, 18 September 2013 (doi:10.1177/ 1753425913501706
21. He S, Liang Y, Shao F, et al. (2011). Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway. Proc Natl Acad Sci USA 108:20054-9
22. Hong SP, Kim MJ, Jung M-Y, et al. (2008). Biopositive effects of low-dose UVB on epidermis: Coordinate upregulation of antimicrobial peptides and permeability barrier reinforcement. J Invest Dermatol 128:2880-7
23. Ichihashi M, Ueda M, Budiyanto A, et al. (2003). UV-induced skin damage. Toxicology 189:21-39
24. Institute of Medicine. (2011). Dietary reference intakes for calcium and vitamin D. Natl Acadamies Press: Washington DC, USA, 1116pp
25. Ishii KJ, Suzuki K, Coban C, et al. (2001). Genomic DNA released by dying cells induces the maturation of APCs. J Immunol 167:2602-7
26. Jekler J, Larkö O. (1988). UVB phototherapy of atopic dermatitis. Br J Dermatol 119:697-705
27. Johnson KE, Wulff BC, Oberyszyn TM, et al. (2013). Ultraviolet light exposure stimulates HMGB1 release by keratinocytes. Arch Dermatol Res 305: 805-15
28. Kaczmarek A, Vandenabeele P, Krysko DV. (2013). Necroptosis: The release of damage-Associated molecular patterns and its physiological relevance. Immunity 38:209-23
29. Karikó K, Ni H, Capodici J, et al. (2004). mRNA is an endogenous ligand for Toll-like receptor 3. J Biol Chem 279:12542-50
30. Kono H, Rock KL. (2008). How dying cells alert the immune system to danger. Nat Rev Immunol 8:279-89
31. Krysko DV, Vanden Berghe T, D'HerDe K, et al. (2008). Apoptosis and necrosis: Detection, discrimination and phagocytosis. Methods 44:205-21
32. Lai Y, Di Nardo A, Nakatsuji T, et al. (2009). Commensal bacteria regulate Toll-like receptor 3-dependent inflammation after skin injury. Nat Med 15:1377-82
33. Lebre MC, Van Der Aar AMG, Van Baarsen L, et al. (2007). Human keratinocytes express functional Toll-like receptor 3, 4, 5, and 9. J Invest Dermatol 127:331-41
34. Lehmann P, Hölzle E, Melnik B, et al. (1991). Effects of ultraviolet A and B on the skin barrier: A functional, electron microscopic and lipid biochemical study. Photodermatol Photoimmunol Photomed 8:129-34
35. Lewis W, Simanyi E, Li H, et al. (2011). Regulation of ultraviolet radiation induced cutaneous photoimmunosuppression by toll-like receptor-4. Arch Biochem Biophys 508:171-7
36. Li G, Tron V, Ho V. (1998). Induction of squamous cell carcinoma in p53-deficient mice after ultraviolet irradiation. J Invest Dermatol 110:72-5
37. Lian L-H, Milora Ka, Manupipatpong KK, et al. (2012). The double-stranded RNA analogue polyinosinic-polycytidylic acid induces keratinocyte pyroptosis and release of IL-36g. J Invest Dermatol 132:1346-53
38. Lin Q, Fang D, Fang J, et al. (2011). Impaired wound healing with defective expression of chemokines and recruitment of myeloid cells in TLR3-deficient mice. J Immunol 186:3710-7
39. Lin Q, Wang L, Lin Y, et al. (2012). Toll-like receptor 3 ligand polyinosinic: Polycytidylic acid promotes wound healing in human and murine skin. J Invest Dermatol 132:2085-92
40. Liu L, Botos I, Wang Y, et al. (2008). Structural basis of toll-like receptor 3 signaling with double-stranded RNA. Science 320:379-81
41. Loser K, Apelt J, Voskort M, et al. (2007). IL-10 controls ultraviolet-induced carcinogenesis in mice. J Immunol 179:365-71
42. Lu B, Nakamura T, Inouye K, et al. (2012). Novel role of PKR in inflammasome activation and HMGB1 release. Nature 488:670-4
43. Lucas R, McMichael T, Smith W, et al. (2006). Solar ultraviolet radiation: Global burden of disease from solar ultraviolet radiation. In: Environ. Burd. Dis. Ser. No. 13. Prüss-Üstün A, Zeeb H, Mathers C, et al. (eds). WHO Document Production Services: Geneva, 87 p.p.
44. Mammone T, Gan D, Collins D, et al. (2000). Successful separation of apoptosis and necrosis pathways in HaCaT keratinocyte cells induced by UVB irradiation. Cell Biol Toxicol 16:293-302
45. Martin P, Leibovich SJ. (2005). Inflammatory cells during wound repair: The good, the bad and the ugly. Trends Cell Biol 15:599-607
46. Mittal D, Saccheri F, Vénéreau E, et al. (2010). TLR4-mediated skin carcinogenesis is dependent on immune and radioresistant cells. EMBO J 29:2242-52
47. Muto J, Morioka Y, Yamasaki K. (2014). Hyaluronan digestion controls DC migration from the skin. J Clin Invest 124:1309-19
48. Picot E, Meunier L, Picot-Debeze MC, et al. (1992). Treatment of psoriasis with a 311-nm UVB lamp. Br J Dermatol 127:509-12
49. Rass K, Reichrath J. (2008). UV damage and DNA repair in malignant melanoma and nonmelanoma skin cancer. Adv Exp Med Biol 624:162-78
50. Rehemtulla A, Hamilton C. (1997). Ultraviolet radiation-induced apoptosis is mediated by activation of CD-95 (Fas/APO-1). J Biol Chem 272: 25783-6
51. Ross AC, Manson JE, Abrams SA, et al. (2011). The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: What clinicians need to know. J Clin Endocrinol Metab 96:53-8
52. Ryckman C, Vandal K, Rouleau P, et al. (2003). Proinflammatory activities of S100: Proteins S100A8, S100A9, and S100A8/A9 induce neutrophil chemotaxis and adhesion. J Immunol 170:3233-42
53. Scaffidi P, Misteli T, Bianchi ME. (2002). Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 418:191-5
54. Scheibner Ka, Lutz Ma, Boodoo S, et al. (2006). Hyaluronan fragments act as an endogenous danger signal by engaging TLR2. J Immunol 177: 1272-81
55. Semino C, Angelini G, Poggi A, et al. (2005). NK/iDC interaction results in IL-18 secretion by DCs at the synaptic cleft followed by NK cell activation and release of the DC maturation factor HMGB1. Blood 106: 609-16
56. Shi Y, Evans JE, Rock KL. (2003). Molecular identification of a danger signal that alerts the immune system to dying cells. Nature 425:516-21
57. Tabas I. (2010). Macrophage death and defective inflammation resolution in atherosclerosis. Nat Rev Immunol 10:36-46
58. Taylor KR, Trowbridge JM, Rudisill JA, et al. (2004). Hyaluronan fragments stimulate endothelial recognition of injury through TLR4. J Biol Chem 279:17079-84
59. Voll R, Herrmann M, Roth E, et al. (1997). Immunosuppressive effects of apoptotic cells. Nature 534:350-1
60. Wang H, Bloom O, Zhang M, et al. (1999). HMG-1 as a late mediator of endotoxin lethality in mice. Science 285:248-51
61. Weber F, Wagner V, Rasmussen SB, et al. (2006). Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA Viruses. J Virol 80:5059-64
62. Young AR. (1987). The sunburn cell. Photodermatol 4:127-34.