Spontaneous self-assembly of pathogenic huntingtin exon 1 protein into amyloid structures

Essays in Biochemistry

Volumn 56, Issue 1, 2014, Pages 167-180

  Trepte, Philipp ^a   Strempel, Nadine ^a   Wanker, Erich E ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

( ) Epigallocatechin gallate (EGCG); Chaperone; Huntington's disease; Inclusion body; Nucleation dependent polymerization; Polyglutamine disease; Protein aggregation

Indexed keywords

AMYLOID; HTT PROTEIN, HUMAN; NERVE PROTEIN; PEPTIDE; POLYGLUTAMINE;

ANIMAL; CHEMISTRY; EXON; GENETICS; HUMAN; HUNTINGTON CHOREA; METABOLISM; MUTATION; PATHOLOGY; PROTEIN FOLDING; PROTEIN MULTIMERIZATION; PROTEINOSIS; ULTRASTRUCTURE;

AMYLOID; ANIMALS; EXONS; HUMANS; HUNTINGTON DISEASE; MUTATION; NERVE TISSUE PROTEINS; PEPTIDES; PROTEIN AGGREGATION, PATHOLOGICAL; PROTEIN FOLDING; PROTEIN MULTIMERIZATION;

EID: 84906255971     PISSN: 00711365     EISSN: None     Source Type: Journal    
DOI: 10.1042/BSE0560167     Document Type: Article

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