메뉴 건너뛰기




Volumn 352, Issue 1, 2014, Pages 126-136

Omics-based nanomedicine: The future of personalized oncology

Author keywords

Nanomedicine; Omics; Personalized medicine; RNAi; Theranostics

Indexed keywords

ANTINEOPLASTIC AGENT; BRCA1 PROTEIN; BRCA2 PROTEIN; CARBOPLATIN; CETUXIMAB; CHIMERIC ANTIGEN RECEPTOR; CRIZOTINIB; DAUNORUBICIN; DOCETAXEL; DOXORUBICIN; FERUCARBOTRAN; GADOLINIUM; GEMCITABINE; INIPARIB; LIPOSOME; MANGANESE; NANOCARRIER; PACLITAXEL; PANITUMUMAB; PEMETREXED; SGT 53; SMALL INTERFERING RNA; SUPERPARAMAGNETIC IRON OXIDE; TRASTUZUMAB; UNCLASSIFIED DRUG;

EID: 84906064921     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2013.07.029     Document Type: Review
Times cited : (66)

References (105)
  • 3
    • 84869792625 scopus 로고    scopus 로고
    • Targeted nanotheranostics for personalized cancer therapy
    • Diou O., Tsapis N., Fattal E. Targeted nanotheranostics for personalized cancer therapy. Exp. Opin. Drug Deliv. 2012, 9:1475-1487.
    • (2012) Exp. Opin. Drug Deliv. , vol.9 , pp. 1475-1487
    • Diou, O.1    Tsapis, N.2    Fattal, E.3
  • 4
    • 28544446695 scopus 로고    scopus 로고
    • Biomarkers in cancer staging, prognosis and treatment selection
    • Ludwig J.A., Weinstein J.N. Biomarkers in cancer staging, prognosis and treatment selection. Nat. Rev. Cancer 2005, 5:845-856.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 845-856
    • Ludwig, J.A.1    Weinstein, J.N.2
  • 7
    • 84867642276 scopus 로고    scopus 로고
    • RNAi-based nanomedicines for targeted personalized therapy
    • Daka A., Peer D. RNAi-based nanomedicines for targeted personalized therapy. Adv. Drug Deliv. Rev. 2012, 64:1508-1521.
    • (2012) Adv. Drug Deliv. Rev. , vol.64 , pp. 1508-1521
    • Daka, A.1    Peer, D.2
  • 8
    • 84876582076 scopus 로고    scopus 로고
    • Harnessing nanomedicine for mucosal theranostics - a silver bullet at last?
    • Elinav E., Peer D. Harnessing nanomedicine for mucosal theranostics - a silver bullet at last?. ACS Nano 2013, 7:2883-2890.
    • (2013) ACS Nano , vol.7 , pp. 2883-2890
    • Elinav, E.1    Peer, D.2
  • 9
    • 84873275186 scopus 로고    scopus 로고
    • Cancer nanomedicines: so many papers and so few drugs!
    • Venditto V.J., Szoka F.C. Cancer nanomedicines: so many papers and so few drugs!. Adv. Drug Deliv. Rev. 2013, 65:80-88.
    • (2013) Adv. Drug Deliv. Rev. , vol.65 , pp. 80-88
    • Venditto, V.J.1    Szoka, F.C.2
  • 13
    • 84867627449 scopus 로고    scopus 로고
    • Nanotheranostics for personalized medicine
    • Mura S., Couvreur P. Nanotheranostics for personalized medicine. Adv. Drug Deliv. Rev. 2012, 64:1394-1416.
    • (2012) Adv. Drug Deliv. Rev. , vol.64 , pp. 1394-1416
    • Mura, S.1    Couvreur, P.2
  • 14
    • 77954827460 scopus 로고    scopus 로고
    • The path to personalized medicine
    • Hamburg M.A., Collins F.S. The path to personalized medicine. New Engl. J. Med. 2010, 363:301-304.
    • (2010) New Engl. J. Med. , vol.363 , pp. 301-304
    • Hamburg, M.A.1    Collins, F.S.2
  • 16
    • 84874144193 scopus 로고    scopus 로고
    • Personalized cancer medicine: molecular diagnostics, predictive biomarkers, and drug resistance
    • Gonzalez de Castro D., Clarke P.A., Al-Lazikani B., Workman P. Personalized cancer medicine: molecular diagnostics, predictive biomarkers, and drug resistance. Clin. Pharmacol. Ther. 2013, 93:252-259.
    • (2013) Clin. Pharmacol. Ther. , vol.93 , pp. 252-259
    • Gonzalez de Castro, D.1    Clarke, P.A.2    Al-Lazikani, B.3    Workman, P.4
  • 19
    • 84906045256 scopus 로고    scopus 로고
    • National Cancer Institute. Bethesda, SEER Cancer Statistics Review, 1975-2005.
    • National Cancer Institute. Bethesda, SEER Cancer Statistics Review, 1975-2005. , 2008. http://seer.cancer.gov/csr/1975_2005/.
    • (2008)
  • 23
    • 78751614476 scopus 로고    scopus 로고
    • PARP and cancer-if it is broke, do not fix it
    • Carey L.A., Sharpless N.E. PARP and cancer-if it is broke, do not fix it. New Engl. J. Med. 2011, 364:277-279.
    • (2011) New Engl. J. Med. , vol.364 , pp. 277-279
    • Carey, L.A.1    Sharpless, N.E.2
  • 24
    • 84869492811 scopus 로고    scopus 로고
    • Molecular-targeted therapies for ovarian cancer: prospects for the future
    • Sudo T. Molecular-targeted therapies for ovarian cancer: prospects for the future. Int. J. Clin. Oncol. 2012, 17:424-429.
    • (2012) Int. J. Clin. Oncol. , vol.17 , pp. 424-429
    • Sudo, T.1
  • 27
    • 80655126743 scopus 로고    scopus 로고
    • ALK and NSCLC targeted therapy with ALK inhibitors
    • Hallberg B., Palmer R.H. ALK and NSCLC targeted therapy with ALK inhibitors. F1000 Med. Rep. 2011, 3:21.
    • (2011) F1000 Med. Rep. , vol.3 , pp. 21
    • Hallberg, B.1    Palmer, R.H.2
  • 30
    • 65249101637 scopus 로고    scopus 로고
    • The promise and potential pitfalls of chimeric antigen receptors
    • Sadelain M., Brentjens R., Riviere I. The promise and potential pitfalls of chimeric antigen receptors. Curr. Opin. Immunol. 2009, 21:215-223.
    • (2009) Curr. Opin. Immunol. , vol.21 , pp. 215-223
    • Sadelain, M.1    Brentjens, R.2    Riviere, I.3
  • 33
    • 84877666359 scopus 로고    scopus 로고
    • How do CARs work? Early insights from recent clinical studies targeting CD19
    • Davila M.L., Brentjens R., Wang X.Y., Riviere I., Sadelain M. How do CARs work? Early insights from recent clinical studies targeting CD19. Oncoimmunology 2012, 1:1577-1583.
    • (2012) Oncoimmunology , vol.1 , pp. 1577-1583
    • Davila, M.L.1    Brentjens, R.2    Wang, X.Y.3    Riviere, I.4    Sadelain, M.5
  • 35
    • 77956535599 scopus 로고    scopus 로고
    • Redirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptor
    • Jena B., Dotti G., Cooper L.J. Redirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptor. Blood 2010, 116:1035-1044.
    • (2010) Blood , vol.116 , pp. 1035-1044
    • Jena, B.1    Dotti, G.2    Cooper, L.J.3
  • 37
    • 80053628299 scopus 로고    scopus 로고
    • Sequencing technologies and genome sequencing
    • Pareek C.S., Smoczynski R., Tretyn A. Sequencing technologies and genome sequencing. J. Appl. Gen. 2011, 52:413-435.
    • (2011) J. Appl. Gen. , vol.52 , pp. 413-435
    • Pareek, C.S.1    Smoczynski, R.2    Tretyn, A.3
  • 38
    • 84874865318 scopus 로고    scopus 로고
    • Next generation sequencing in cancer research and clinical application
    • Shyr D., Liu Q. Next generation sequencing in cancer research and clinical application. Biol. Proced. Online 2013, 15:4.
    • (2013) Biol. Proced. Online , vol.15 , pp. 4
    • Shyr, D.1    Liu, Q.2
  • 39
    • 84877028141 scopus 로고    scopus 로고
    • Comprehensive molecular portraits of human breast tumors
    • N.Cancer Genome Atlas
    • N.Cancer Genome Atlas Comprehensive molecular portraits of human breast tumors. Nature 2012, 490:61-70.
    • (2012) Nature , vol.490 , pp. 61-70
  • 40
    • 79959838081 scopus 로고    scopus 로고
    • Integrated genomic analyses of ovarian carcinoma
    • N.Cancer Genome Atlas Research
    • N.Cancer Genome Atlas Research Integrated genomic analyses of ovarian carcinoma. Nature 2011, 474:609-615.
    • (2011) Nature , vol.474 , pp. 609-615
  • 41
    • 84863922124 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of human colon and rectal cancer
    • N.Cancer Genome Atlas
    • N.Cancer Genome Atlas Comprehensive molecular characterization of human colon and rectal cancer. Nature 2012, 487:330-337.
    • (2012) Nature , vol.487 , pp. 330-337
  • 42
    • 84866894408 scopus 로고    scopus 로고
    • Comprehensive genomic characterization of squamous cell lung cancers
    • N.Cancer Genome Atlas Research
    • N.Cancer Genome Atlas Research Comprehensive genomic characterization of squamous cell lung cancers. Nature 2012, 489:519-525.
    • (2012) Nature , vol.489 , pp. 519-525
  • 44
    • 79955768389 scopus 로고    scopus 로고
    • Pharmacogenetics, pharmacogenomics, and individualized medicine
    • Ma Q., Lu A.Y. Pharmacogenetics, pharmacogenomics, and individualized medicine. Pharmacol. Rev. 2011, 63:437-459.
    • (2011) Pharmacol. Rev. , vol.63 , pp. 437-459
    • Ma, Q.1    Lu, A.Y.2
  • 45
    • 33847120804 scopus 로고    scopus 로고
    • Identification of potential markers for the detection of pancreatic cancer through comparative serum protein expression profiling
    • Ehmann M., Felix K., Hartmann D., Schnolzer M., Nees M., Vorderwulbecke S., Bogumil R., Buchler M.W., Friess H. Identification of potential markers for the detection of pancreatic cancer through comparative serum protein expression profiling. Pancreas 2007, 34:205-214.
    • (2007) Pancreas , vol.34 , pp. 205-214
    • Ehmann, M.1    Felix, K.2    Hartmann, D.3    Schnolzer, M.4    Nees, M.5    Vorderwulbecke, S.6    Bogumil, R.7    Buchler, M.W.8    Friess, H.9
  • 47
    • 84873463640 scopus 로고    scopus 로고
    • Proteomic approaches to the discovery of cancer biomarkers for early detection and personalized medicine
    • Honda K., Ono M., Shitashige M., Masuda M., Kamita M., Miura N., Yamada T. Proteomic approaches to the discovery of cancer biomarkers for early detection and personalized medicine. Jpn. J. Clin. Oncol. 2013, 43:103-109.
    • (2013) Jpn. J. Clin. Oncol. , vol.43 , pp. 103-109
    • Honda, K.1    Ono, M.2    Shitashige, M.3    Masuda, M.4    Kamita, M.5    Miura, N.6    Yamada, T.7
  • 51
    • 82555195566 scopus 로고    scopus 로고
    • Single-cell analysis: the deepest differences
    • Schubert C. Single-cell analysis: the deepest differences. Nature 2011, 480:133-137.
    • (2011) Nature , vol.480 , pp. 133-137
    • Schubert, C.1
  • 52
    • 72849144434 scopus 로고    scopus 로고
    • Applications of next-generation sequencing sequencing technologies - the next generation
    • Metzker M.L. Applications of next-generation sequencing sequencing technologies - the next generation. Nat. Rev. Genet 2010, 11:31-46.
    • (2010) Nat. Rev. Genet , vol.11 , pp. 31-46
    • Metzker, M.L.1
  • 53
    • 75549083303 scopus 로고
    • Tumor heterogeneity: causes and consequences
    • Marusyk A., Polyak K. Tumor heterogeneity: causes and consequences. Bba - Rev. Cancer 1805, 2010:105-117.
    • (1805) Bba - Rev. Cancer , vol.2010 , pp. 105-117
    • Marusyk, A.1    Polyak, K.2
  • 54
    • 77953121190 scopus 로고    scopus 로고
    • Single cell analysis: the new frontier in 'omics'
    • Wang D., Bodovitz S. Single cell analysis: the new frontier in 'omics'. Trends Biotechnol. 2010, 28:281-290.
    • (2010) Trends Biotechnol. , vol.28 , pp. 281-290
    • Wang, D.1    Bodovitz, S.2
  • 58
    • 77957916296 scopus 로고    scopus 로고
    • Rapid isolation and detection of cancer cells by utilizing integrated microfluidic systems
    • Lien K.Y., Chuang Y.H., Hung L.Y., Hsu K.F., Lai W.W., Ho C.L., Chou C.Y., Lee G.B. Rapid isolation and detection of cancer cells by utilizing integrated microfluidic systems. Lab Chip 2010, 10:2875-2886.
    • (2010) Lab Chip , vol.10 , pp. 2875-2886
    • Lien, K.Y.1    Chuang, Y.H.2    Hung, L.Y.3    Hsu, K.F.4    Lai, W.W.5    Ho, C.L.6    Chou, C.Y.7    Lee, G.B.8
  • 60
    • 84860708527 scopus 로고    scopus 로고
    • Liposomes, lipid biophysics, and sphingolipid research: from basic to translation research
    • Barenholz Y.C., Peer D. Liposomes, lipid biophysics, and sphingolipid research: from basic to translation research. Chem. Phys. Lipids 2012, 165:363-364.
    • (2012) Chem. Phys. Lipids , vol.165 , pp. 363-364
    • Barenholz, Y.C.1    Peer, D.2
  • 61
    • 84861697192 scopus 로고    scopus 로고
    • Liposomes and other assemblies as drugs and nano-drugs: from basic and translational research to the clinics
    • Barenholz Y., Peer D. Liposomes and other assemblies as drugs and nano-drugs: from basic and translational research to the clinics. J. Controlled Release: Official J. Controlled Release Soc. 2012, 160:115-116.
    • (2012) J. Controlled Release: Official J. Controlled Release Soc. , vol.160 , pp. 115-116
    • Barenholz, Y.1    Peer, D.2
  • 62
    • 84875801524 scopus 로고    scopus 로고
    • A daunting task: manipulating leukocyte function with RNAi
    • Peer D. A daunting task: manipulating leukocyte function with RNAi. Immunol. Rev. 2013, 253:185-197.
    • (2013) Immunol. Rev. , vol.253 , pp. 185-197
    • Peer, D.1
  • 63
    • 84875873258 scopus 로고    scopus 로고
    • Marqibo(R) (vincristine sulfate liposome injection) improves the pharmacokinetics and pharmacodynamics of vincristine
    • Silverman J.A., Deitcher S.R. Marqibo(R) (vincristine sulfate liposome injection) improves the pharmacokinetics and pharmacodynamics of vincristine. Cancer Chemother. Pharmacol. 2013, 71:555-564.
    • (2013) Cancer Chemother. Pharmacol. , vol.71 , pp. 555-564
    • Silverman, J.A.1    Deitcher, S.R.2
  • 65
    • 84885483584 scopus 로고    scopus 로고
    • Recent trends in multifunctional liposomal nanocarriers for enhanced tumor targeting
    • Perche F., Torchilin V.P. Recent trends in multifunctional liposomal nanocarriers for enhanced tumor targeting. J. Drug Deliv. 2013, 2013:705265.
    • (2013) J. Drug Deliv. , vol.2013 , pp. 705265
    • Perche, F.1    Torchilin, V.P.2
  • 68
    • 78649529391 scopus 로고    scopus 로고
    • Induction of therapeutic gene silencing in leukocyte-implicated diseases by targeted and stabilized nanoparticles: a mini-review
    • Peer D. Induction of therapeutic gene silencing in leukocyte-implicated diseases by targeted and stabilized nanoparticles: a mini-review. J. Controlled Release: Official J. Controlled Release Soc. 2010, 148:63-68.
    • (2010) J. Controlled Release: Official J. Controlled Release Soc. , vol.148 , pp. 63-68
    • Peer, D.1
  • 69
    • 77952365921 scopus 로고    scopus 로고
    • Efficacy, biodistribution, and pharmacokinetics of CD22-targeted pegylated liposomal doxorubicin in a B-cell non-Hodgkin's lymphoma xenograft mouse model
    • Tuscano J.M., Martin S.M., Ma Y., Zamboni W., O'Donnell R.T. Efficacy, biodistribution, and pharmacokinetics of CD22-targeted pegylated liposomal doxorubicin in a B-cell non-Hodgkin's lymphoma xenograft mouse model. Clin. Cancer Res.: Official J. Am. Assoc. Cancer Res. 2010, 16:2760-2768.
    • (2010) Clin. Cancer Res.: Official J. Am. Assoc. Cancer Res. , vol.16 , pp. 2760-2768
    • Tuscano, J.M.1    Martin, S.M.2    Ma, Y.3    Zamboni, W.4    O'Donnell, R.T.5
  • 71
    • 35848961893 scopus 로고    scopus 로고
    • Antitumor effect of paclitaxel-loaded PEGylated immunoliposomes against human breast cancer cells
    • Yang T., Choi M.K., Cui F.D., Lee S.J., Chung S.J., Shim C.K., Kim D.D. Antitumor effect of paclitaxel-loaded PEGylated immunoliposomes against human breast cancer cells. Pharm. Res. 2007, 24:2402-2411.
    • (2007) Pharm. Res. , vol.24 , pp. 2402-2411
    • Yang, T.1    Choi, M.K.2    Cui, F.D.3    Lee, S.J.4    Chung, S.J.5    Shim, C.K.6    Kim, D.D.7
  • 72
    • 84868353843 scopus 로고    scopus 로고
    • Engineering imaging probes and molecular machines for nanomedicine
    • Tong S., Cradick T.J., Ma Y., Dai Z., Bao G. Engineering imaging probes and molecular machines for nanomedicine. Sci. China Life Sci. 2012, 55:843-861.
    • (2012) Sci. China Life Sci. , vol.55 , pp. 843-861
    • Tong, S.1    Cradick, T.J.2    Ma, Y.3    Dai, Z.4    Bao, G.5
  • 73
    • 79551704757 scopus 로고    scopus 로고
    • Nanoparticles as magnetic resonance imaging contrast agents for vascular and cardiac diseases
    • Chen W., Cormode D.P., Fayad Z.A., Mulder W.J.M. Nanoparticles as magnetic resonance imaging contrast agents for vascular and cardiac diseases. Wires Nanomed. Nanobi. 2011, 3:146-161.
    • (2011) Wires Nanomed. Nanobi. , vol.3 , pp. 146-161
    • Chen, W.1    Cormode, D.P.2    Fayad, Z.A.3    Mulder, W.J.M.4
  • 74
    • 79955619426 scopus 로고    scopus 로고
    • Superparamagnetic nanosystems based on iron oxide nanoparticles for biomedical imaging
    • Liu F.J., Laurent S., Fattahi H., Elst L.V., Muller R.N. Superparamagnetic nanosystems based on iron oxide nanoparticles for biomedical imaging. Nanomed. UK 2011, 6:519-528.
    • (2011) Nanomed. UK , vol.6 , pp. 519-528
    • Liu, F.J.1    Laurent, S.2    Fattahi, H.3    Elst, L.V.4    Muller, R.N.5
  • 75
    • 79451473831 scopus 로고    scopus 로고
    • Nanoparticles as contrast agents for in-vivo bioimaging: current status and future perspectives
    • Hahn M.A., Singh A.K., Sharma P., Brown S.C., Moudgil B.M. Nanoparticles as contrast agents for in-vivo bioimaging: current status and future perspectives. Anal. Bioanal. Chem. 2011, 399:3-27.
    • (2011) Anal. Bioanal. Chem. , vol.399 , pp. 3-27
    • Hahn, M.A.1    Singh, A.K.2    Sharma, P.3    Brown, S.C.4    Moudgil, B.M.5
  • 76
    • 36048993546 scopus 로고    scopus 로고
    • Nanoplatforms for targeted molecular imaging in living subjects
    • Cai W.B., Chen X.Y. Nanoplatforms for targeted molecular imaging in living subjects. Small 2007, 3:1840-1854.
    • (2007) Small , vol.3 , pp. 1840-1854
    • Cai, W.B.1    Chen, X.Y.2
  • 77
    • 58149083378 scopus 로고    scopus 로고
    • Synergistically integrated nanoparticles as multimodal probes for nanobiotechnology
    • Cheon J., Lee J.H. Synergistically integrated nanoparticles as multimodal probes for nanobiotechnology. Acc. Chem. Res. 2008, 41:1630-1640.
    • (2008) Acc. Chem. Res. , vol.41 , pp. 1630-1640
    • Cheon, J.1    Lee, J.H.2
  • 78
    • 33748616254 scopus 로고    scopus 로고
    • Anti-angiogenic cancer therapy based on integrin alphavbeta3 antagonism
    • Cai W., Chen X. Anti-angiogenic cancer therapy based on integrin alphavbeta3 antagonism. Anti-cancer Agents Med. Chem. 2006, 6:407-428.
    • (2006) Anti-cancer Agents Med. Chem. , vol.6 , pp. 407-428
    • Cai, W.1    Chen, X.2
  • 81
    • 79953752997 scopus 로고    scopus 로고
    • Non-invasive tumor detection in small animals using novel functional Pluronic nanomicelles conjugated with anti-mesothelin antibody
    • Ding H., Yong K.T., Law W.C., Roy I., Hu R., Wu F., Zhao W., Huang K., Erogbogbo F., Bergey E.J., Prasad P.N. Non-invasive tumor detection in small animals using novel functional Pluronic nanomicelles conjugated with anti-mesothelin antibody. Nanoscale 2011, 3:1813-1822.
    • (2011) Nanoscale , vol.3 , pp. 1813-1822
    • Ding, H.1    Yong, K.T.2    Law, W.C.3    Roy, I.4    Hu, R.5    Wu, F.6    Zhao, W.7    Huang, K.8    Erogbogbo, F.9    Bergey, E.J.10    Prasad, P.N.11
  • 83
    • 78649844305 scopus 로고    scopus 로고
    • Magnetic resonance and fluorescence imaging of doxorubicin-loaded nanoparticles using a novel in vivo model
    • Erten A., Wrasidlo W., Scadeng M., Esener S., Hoffman R.M., Bouvet M., Makale M. Magnetic resonance and fluorescence imaging of doxorubicin-loaded nanoparticles using a novel in vivo model. Nanomed. UK 2010, 6:797-807.
    • (2010) Nanomed. UK , vol.6 , pp. 797-807
    • Erten, A.1    Wrasidlo, W.2    Scadeng, M.3    Esener, S.4    Hoffman, R.M.5    Bouvet, M.6    Makale, M.7
  • 84
    • 65149101001 scopus 로고    scopus 로고
    • Thermosensitive liposomes entrapping iron oxide nanoparticles for controllable drug release
    • Tai L.A., Tsai P.J., Wang Y.C., Wang Y.J., Lo L.W., Yang C.S. Thermosensitive liposomes entrapping iron oxide nanoparticles for controllable drug release. Nanotechnology 2009, 20:135101.
    • (2009) Nanotechnology , vol.20 , pp. 135101
    • Tai, L.A.1    Tsai, P.J.2    Wang, Y.C.3    Wang, Y.J.4    Lo, L.W.5    Yang, C.S.6
  • 85
    • 77950273997 scopus 로고    scopus 로고
    • Combined delivery and magnetic resonance imaging of neural cell adhesion molecule-targeted doxorubicin-containing liposomes in experimentally induced Kaposi's sarcoma
    • Grange C., Geninatti-Crich S., Esposito G., Alberti D., Tei L., Bussolati B., Aime S., Camussi G. Combined delivery and magnetic resonance imaging of neural cell adhesion molecule-targeted doxorubicin-containing liposomes in experimentally induced Kaposi's sarcoma. Cancer Res. 2010, 70:2180-2190.
    • (2010) Cancer Res. , vol.70 , pp. 2180-2190
    • Grange, C.1    Geninatti-Crich, S.2    Esposito, G.3    Alberti, D.4    Tei, L.5    Bussolati, B.6    Aime, S.7    Camussi, G.8
  • 87
    • 77952585292 scopus 로고    scopus 로고
    • Targeted near-IR QDs-loaded micelles for cancer therapy and imaging
    • Nurunnabi M., Cho K.J., Choi J.S., Huh K.M., Lee Y.K. Targeted near-IR QDs-loaded micelles for cancer therapy and imaging. Biomaterials 2010, 31:5436-5444.
    • (2010) Biomaterials , vol.31 , pp. 5436-5444
    • Nurunnabi, M.1    Cho, K.J.2    Choi, J.S.3    Huh, K.M.4    Lee, Y.K.5
  • 88
    • 83255185737 scopus 로고    scopus 로고
    • Special delivery: targeted therapy with small RNAs
    • Peer D., Lieberman J. Special delivery: targeted therapy with small RNAs. Gene Ther. 2011, 18:1127-1133.
    • (2011) Gene Ther. , vol.18 , pp. 1127-1133
    • Peer, D.1    Lieberman, J.2
  • 89
    • 26944498261 scopus 로고    scopus 로고
    • Approaches for chemically synthesized siRNA and vector-mediated RNAi
    • Amarzguioui M., Rossi J.J., Kim D. Approaches for chemically synthesized siRNA and vector-mediated RNAi. FEBS Lett. 2005, 579:5974-5981.
    • (2005) FEBS Lett. , vol.579 , pp. 5974-5981
    • Amarzguioui, M.1    Rossi, J.J.2    Kim, D.3
  • 90
    • 38849166053 scopus 로고    scopus 로고
    • Systemic leukocyte-directed siRNA delivery revealing cyclin D1 as an anti-inflammatory target
    • Peer D., Park E.J., Morishita Y., Carman C.V., Shimaoka M. Systemic leukocyte-directed siRNA delivery revealing cyclin D1 as an anti-inflammatory target. Science 2008, 319:627-630.
    • (2008) Science , vol.319 , pp. 627-630
    • Peer, D.1    Park, E.J.2    Morishita, Y.3    Carman, C.V.4    Shimaoka, M.5
  • 91
    • 31544456413 scopus 로고    scopus 로고
    • Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging
    • Bartlett D.W., Davis M.E. Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging. Nucl. Acids Res. 2006, 34:322-333.
    • (2006) Nucl. Acids Res. , vol.34 , pp. 322-333
    • Bartlett, D.W.1    Davis, M.E.2
  • 97
    • 81855218204 scopus 로고    scopus 로고
    • Reshaping the future of nanopharmaceuticals: Ad iudicium
    • Moghimi S.M., Peer D., Langer R. Reshaping the future of nanopharmaceuticals: Ad iudicium. ACS Nano 2011, 5:8454-8458.
    • (2011) ACS Nano , vol.5 , pp. 8454-8458
    • Moghimi, S.M.1    Peer, D.2    Langer, R.3
  • 98
    • 80053977936 scopus 로고    scopus 로고
    • Resistance to chemotherapy and molecularly targeted therapies: rationale for combination therapy in malignant melanoma
    • Wu S., Singh R.K. Resistance to chemotherapy and molecularly targeted therapies: rationale for combination therapy in malignant melanoma. Curr. Mol. Med. 2011, 11:553-563.
    • (2011) Curr. Mol. Med. , vol.11 , pp. 553-563
    • Wu, S.1    Singh, R.K.2
  • 99
    • 77956269093 scopus 로고    scopus 로고
    • Nanoparticles modified with tumor-targeting scFv deliver siRNA and miRNA for cancer therapy
    • Chen Y.C., Zhu X.D., Zhang X.J., Liu B., Huang L. Nanoparticles modified with tumor-targeting scFv deliver siRNA and miRNA for cancer therapy. Mol. Ther. 2010, 18:1650-1656.
    • (2010) Mol. Ther. , vol.18 , pp. 1650-1656
    • Chen, Y.C.1    Zhu, X.D.2    Zhang, X.J.3    Liu, B.4    Huang, L.5
  • 101
    • 84863164382 scopus 로고    scopus 로고
    • Two-in-one: combined targeted chemo and gene therapy for tumor suppression and prevention of metastases
    • Zhang M., Garbuzenko O.B., Reuhl K.R., Rodriguez-Rodriguez L., Minko T. Two-in-one: combined targeted chemo and gene therapy for tumor suppression and prevention of metastases. Nanomedicine (Lond) 2012, 7:185-197.
    • (2012) Nanomedicine (Lond) , vol.7 , pp. 185-197
    • Zhang, M.1    Garbuzenko, O.B.2    Reuhl, K.R.3    Rodriguez-Rodriguez, L.4    Minko, T.5
  • 103
    • 84873406290 scopus 로고    scopus 로고
    • Systemic delivery of modified mRNA encoding herpes simplex virus 1 thymidine kinase for targeted cancer gene therapy
    • Wang Y., Su H.H., Yang Y., Hu Y., Zhang L., Blancafort P., Huang L. Systemic delivery of modified mRNA encoding herpes simplex virus 1 thymidine kinase for targeted cancer gene therapy. Mol. Ther.: J. Am. Soc. Gene Ther. 2013, 21:358-367.
    • (2013) Mol. Ther.: J. Am. Soc. Gene Ther. , vol.21 , pp. 358-367
    • Wang, Y.1    Su, H.H.2    Yang, Y.3    Hu, Y.4    Zhang, L.5    Blancafort, P.6    Huang, L.7
  • 104
    • 84869200994 scopus 로고    scopus 로고
    • Immunotoxicity derived from manipulating leukocytes with lipid-based nanoparticles
    • Peer D. Immunotoxicity derived from manipulating leukocytes with lipid-based nanoparticles. Adv. Drug Deliv. Rev. 2012, 64:1738-1748.
    • (2012) Adv. Drug Deliv. Rev. , vol.64 , pp. 1738-1748
    • Peer, D.1
  • 105
    • 79955645459 scopus 로고    scopus 로고
    • Pfizer reaches out to academia-again
    • Ratner M. Pfizer reaches out to academia-again. Nat. Biotechnol. 2011, 29:3-4.
    • (2011) Nat. Biotechnol. , vol.29 , pp. 3-4
    • Ratner, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.